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List of works by Rithwik Ramachandran

Activities enjoyed by patients with dementia together with their spouses and psychological morbidity in carers.

scientific article published in March 2008

Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways.

scientific article published on 15 July 2009

Biased signalling and proteinase-activated receptors (PARs): targeting inflammatory disease.

scientific article published on March 2014

Characterization of a novel protein from Proatheris superciliaris venom: proatherocytin, a 34-kDa platelet receptor PAR1 agonist

scientific article published on October 2005

Cockroach allergen serine proteinases: Isolation, sequencing and signalling via proteinase-activated receptor-2.

scientific article published on 27 April 2017

Derivatized 2-furoyl-LIGRLO-amide, a versatile and selective probe for proteinase-activated receptor 2: binding and visualization

scientific article

GPCR-mediated EGF receptor transactivation regulates TRPV4 action in the vasculature

scientific article

Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors

scientific article

Implantation serine proteinase 2 is a monomeric enzyme with mixed serine proteolytic activity and can silence signalling via proteinase activated receptors.

scientific article

Inflammatory mediators modulate thrombin and cathepsin-G signaling in human bronchial fibroblasts by inducing expression of proteinase-activated receptor-4.

scientific article

Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts

scientific article published on 13 January 2012

Insulin modulates protease-activated receptor 2 signaling: implications for the innate immune response.

scientific article published on 29 January 2010

Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer

scientific article published on June 2008

Met receptor tyrosine kinase transactivation is involved in proteinase-activated receptor-2-mediated hepatocellular carcinoma cell invasion.

scientific article

MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase-6 regulates astrocyte survival

scientific article published on 22 January 2010

Molecular basis for activation and biased signaling at the thrombin-activated GPCR proteinase activated receptor-4 (PAR4)

scientific article published on 31 December 2019

Myopia-Inhibiting Concentrations of Muscarinic Receptor Antagonists Block Activation of Alpha2A-Adrenoceptors In Vitro

scientific article published on 01 June 2018

Natural-Product-Derived Transient Receptor Potential Melastatin 8 (TRPM8) Channel Modulators.

scientific article

Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder

scientific article

Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2)

scientific article

Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1).

scientific article published on 19 September 2013

Proteinase-Activated Receptor 4 (PAR4) Activation Triggers Cell Membrane Blebbing through RhoA and β-arrestin

scientific article published on 31 March 2020

Proteinase-activated receptor 2 (PAR2) decreases apoptosis in colonic epithelial cells.

scientific article

Proteinase-activated receptor-2 activating peptides: distinct canine coronary artery receptor systems.

scientific article published on 31 August 2007

Proteinase-activated receptor-2 transactivation of epidermal growth factor receptor and transforming growth factor-β receptor signaling pathways contributes to renal fibrosis.

scientific article

Proteinase-activated receptors (PARs): differential signalling by kallikrein-related peptidases KLK8 and KLK14.

scientific article

Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways

scientific article published on May 2014

Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.

scientific article published on 03 December 2007

Proteinases as hormones: targets and mechanisms for proteolytic signaling

scientific article published on August 2008

Proteinases, Their Extracellular Targets, and Inflammatory Signaling.

scientific article published on October 2016

Shear stress sensitizes TRPV4 in endothelium-dependent vasodilatation

scientific article published on 19 May 2018

Single Amino Acid Replacement in G-7039 Leads to a 70-fold Increase in Binding toward GHS-R1a

scientific article published on 30 September 2019

Structure, function and pathophysiology of protease activated receptors.

scientific article published on 26 January 2011

TRPM8 activation attenuates inflammatory responses in mouse models of colitis

scientific article published on 17 April 2013

Targeting a Proteinase-Activated Receptor 4 (PAR4) Carboxyl Terminal Motif to Regulate Platelet Function.

scientific article published on 26 January 2017

Targeting proteinase-activated receptors: therapeutic potential and challenges.

scientific article published on 03 January 2012

The active Zot domain (aa 288–293) increases ZO‐1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO‐1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation ⬇️

scientific article published on September 17, 2010

Thrombin-Mediated Direct Activation of Proteinase-Activated Receptor-2: Another Target for Thrombin Signaling.

scientific article published on 08 March 2016

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