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List of works by Dan Larhammar

A molecular genetic approach to the identification of genes expressed predominantly in the neuroendocrine and immune systems

scientific article

A neuropeptide Y receptor Y1-subfamily gene from an agnathan, the European river lamprey. A potential ancestral gene

scientific article published on December 2001

A proposed bovine neuropeptide Y (NPY) receptor cDNA clone, or its human homologue, confers neither NPY binding sites nor NPY responsiveness on transfected cells

scientific article

Actions of goldfish neuropeptide Y on the secretion of growth hormone and gonadotropin-II in female goldfish

scientific article published in June 1993

Agonists for neuropeptide Y receptors Y1 and Y5 stimulate different phases of feeding in guinea pigs

scientific article

Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins

scientific article

Amino acid sequence homologies between rabbit, rat, and human serum retinol-binding proteins

scientific article published in May 1985

Ancestral vertebrate complexity of the opioid system

scientific article

Ancient Grandeur of the Vertebrate Neuropeptide Y System Shown by the Coelacanth Latimeria chalumnae

scientific article published on 8 March 2013

Binding mode of the peptide YY carboxyterminus to the human Y2 receptor

scientific article published on 24 January 2018

Binding of chimeric NPY/galanin peptides M32 and M242 to cloned neuropeptide Y receptor subtypes Y1, Y2, Y4, and Y5.

scientific article published on June 2001

Binding properties of three neuropeptide Y receptor subtypes from zebrafish: comparison with mammalian Y1 receptors

scientific article published on 01 December 2000

Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.

scientific article published on February 1984

Bradykinin receptors in the zebrafish (Danio rerio).

scientific article

Characterization of NPY receptor subtypes Y2 and Y7 in rainbow trout Oncorhynchus mykiss

scientific article

Characterization of an HLA DR beta pseudogene

scientific article published on March 1985

Characterization of antibodies to synthetic nerve growth factor (NGF) and proNGF peptides

scientific article

Characterization of peptide QRFP (26RFa) and its receptor from amphioxus, Branchiostoma floridae

scientific article published on 25 October 2014

Characterization of the peptide binding requirements for the cloned human pancreatic polypeptide-preferring receptor

scientific article published on 01 July 1996

Characterization of three separated exons in the HLA class II DR region of the human major histocompatibility complex

scientific article published on March 1995

Chicken neuropeptide Y receptor Y2: structural and pharmacological differences to mammalian Y2(1).

scientific article

Chicken neuropeptide Y-family receptor Y4: a receptor with equal affinity for pancreatic polypeptide, neuropeptide Y and peptide YY.

scientific article

Circadian regulation of phosphodiesterase 6 genes in zebrafish differs between cones and rods: Implications for photopic and scotopic vision

scientific article published on 16 December 2019

Class II genes of the human major histocompatibility complex. Comparisons of the DQ and DX alpha and beta genes

scientific article

Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes.

scientific article published in June 1987

Class II genes of the human major histocompatibility complex. Organization and evolutionary relationship of the DR beta genes.

scientific article

Cloning and characterization of a novel neuropeptide Y receptor subtype in the zebrafish

scientific article published in November 1997

Cloning and characterization of the guinea pig neuropeptide Y receptor Y5.

scientific article

Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type ⬇️

scientific article published on June 5, 1992

Cloning and functional expression of the guinea pig neuropeptide Y Y2 receptor

scientific article published in September 1998

Cloning and pharmacological characterization of the neuropeptide Y receptor Y5 in the sea lamprey, Petromyzon marinus

scientific article published on 23 November 2012

Cloning and sequence analysis of the neuropeptide Y receptors Y5 and Y6 in the coelacanth Latimeria chalumnae

scientific article published on 27 October 2006

Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY

scientific article

Cloning of neuropeptide Y, peptide YY, and peptide Y from sea bass (Dicentrarchus labrax), a marine teleost.

scientific article published in May 1998

Cloning of two loci for synapse protein Snap25 in zebrafish: comparison of paralogous linkage groups suggests loss of one locus in the mammalian lineage

scientific article published in December 1998

Cloning, pharmacology, and distribution of the neuropeptide Y-receptor Yb in rainbow trout

scientific article published on March 2003

Cloning, structural characterization and functional expression of a zebrafish bradykinin B2-related receptor.

scientific article

Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes

scientific article

Cocaine-induced reduction of brain neuropeptide Y synthesis dependent on medial prefrontal cortex

scientific article published on March 1991

Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens

scientific article

Complex gene organization of synaptic protein SNAP-25 in Drosophila melanogaster.

scientific article published in July 1997

Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates

scientific article (publication date: 6 May 2010)

Copy number determination of the gene for the human pancreatic polypeptide receptor NPY4R using read depth analysis and droplet digital PCR.

scientific article published on 4 June 2019

Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist circumference.

scientific article published on 5 April 2018

Detection of neuropeptide Y and its mRNA in megakaryocytes: enhanced levels in certain autoimmune mice

scientific article

Developmental expression of NPY/PYY receptors zYb and zYc in zebrafish.

scientific article published in April 2005

Differential distribution of glutamic acid decarboxylase-65 and glutamic acid decarboxylase-67 messenger RNAs in the entopeduncular nucleus of the rat.

scientific article published on May 1997

Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes

scientific article

Differential expression of mRNAs for neuropeptide Y-related peptides in rat nervous tissues: possible evolutionary conservation ⬇️

scientific article published on September 1, 1992

Early duplications of opioid receptor and Peptide genes in vertebrate evolution

scientific article

Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions

scientific article

Effects of a teleost tetraploidization on neuropeptide Y receptor gene repertoire in ray-finned fishes

scientific article

Embryonic expression of the mRNA for the rat homologue of the fusin/CXCR-4 HIV-1 co-receptor

scientific article published on November 1997

Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity

scientific article

Evolution of neuropeptide Y and its related peptides

scientific article published on November 1993

Evolution of the Muscarinic Acetylcholine Receptors in Vertebrates

scientific article published on 01 September 2018

Evolution of the growth hormone, prolactin, prolactin 2 and somatolactin family

scientific article published on 12 January 2018

Evolution of the growth hormone-prolactin-somatolactin system in relation to vertebrate tetraploidizations

scientific article

Evolution of the insulin-like growth factor binding protein (IGFBP) family

scientific article published on 19 April 2011

Evolution of the neuropeptide Y family and its receptors

scientific article published in May 1998

Evolution of the neuropeptide Y family: New genes by chromosome duplications in early vertebrates and in teleost fishes

article

Evolution of the neuropeptide Y receptor family: gene and chromosome duplications deduced from the cloning and mapping of the five receptor subtype genes in pig.

scientific article

Evolution of the receptors for growth hormone, prolactin, erythropoietin and thrombopoietin in relation to the vertebrate tetraploidizations.

scientific article

Evolution of vertebrate nicotinic acetylcholine receptors

scientific article published in 2019

Evolution of vertebrate opioid receptors

scholarly article

Evolution of vertebrate rod and cone phototransduction genes

scientific article published on October 2009

Evolutionary conservation of synaptosome-associated protein 25 kDa (SNAP-25) shown by Drosophila and Torpedo cDNA clones.

scientific article published in November 1993

Evolutionary relationship between HLA-DR antigen beta-chains, HLA-A, B, C antigen subunits and immunoglobulin chains

scientific article published on 01 December 1981

Exon-intron organization and complete nucleotide sequence of a human major histocompatibility antigen DC beta gene ⬇️

scientific article published on December 1, 1983

Expression of a conserved cell-type-specific protein in nerve terminals coincides with synaptogenesis

scientific article

Expression of peptide YY and mRNA for the NPY/PYY receptor of the Y1 subtype in dorsal root ganglia during rat embryogenesis.

scientific article published in November 1993

Extensive duplications of phototransduction genes in early vertebrate evolution correlate with block (chromosome) duplications

scientific article published in May 2004

FISH mapping of the porcine NPY5 gene to chromosome 8p11

scientific article published on 01 March 1998

Family relationships of murine major histocompatibility complex class I genes. Sequence of the T2Aa pseudogene, a member of gene family 3.

scientific article published in May 1988

Functional characterization in vitro of twelve naturally occurring variants of the human pancreatic polypeptide receptor NPY4R

scientific article published on 15 May 2019

Generation of class II antigen polymorphism

scientific article

Globalization of Traditional Chinese Medicine: what are the issues for ensuring evidence-based diagnosis and therapy?

scientific article published on 07 November 2019

Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT(1B) receptor

scientific article

Identification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafish

scientific article (publication date: 2004)

Identification of positions in the human neuropeptide Y/peptide YY receptor Y2 that contribute to pharmacological differences between receptor subtypes.

scientific article

Inhibition of neurotransmitter release in the lamprey reticulospinal synapse by antibody-mediated disruption of SNAP-25 function.

scientific article published in November 1999

Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b.

scientific article published on 15 March 2013

Internalization studies of chimeric neuropeptide Y receptors Y1 and Y2 suggest complex interactions between cytoplasmic domains

scientific article published on 12 April 2011

Isolation and identification of a cDNA clone coding for an HLA-DR transplantation antigen alpha-chain

scientific article published on 01 October 1982

Isolation and identification of a cDNA clone corresponding to an HLA-DR antigen beta chain

scientific article

Localization of neuropeptide Y receptor Y5 mRNA in the guinea pig brain by in situ hybridization

scientific article published on January 2004

Major genomic events and their consequences for vertebrate evolution and endocrinology

scientific article published on April 2009

Major histocompatibility complex (MHC) class II region in humans

scientific article published on 01 January 1991

Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss).

scientific article published on 8 November 2008

Molecular analysis of human class II transplantation antigens and their genes

scientific article published on 01 September 1983

Molecular cloning of a functional human thyrotropin-releasing hormone receptor

scientific article

Molecular evolution of GPCRs: Somatostatin/urotensin II receptors

scientific article

Molecular evolution of NPY receptor subtypes

scientific article

Molecular evolution of the neuropeptide Y (NPY) family of peptides: cloning of three NPY-related peptides from the sea bass (Dicentrarchus labrax)

scientific article published on 01 November 2000

Molecular map of the human HLA-SB (HLA-DP) region and sequence of an SB alpha (DP alpha) pseudogene

scientific article published on December 1984

Mouse MHC class II gene E beta 2 is closely related to E beta and to HLA-DR beta

scientific article published on 01 January 1985

Multiple loci for synapse protein SNAP-25 in the tetraploid goldfish

scientific article published on November 1993

Multiplicity of neuropeptide Y receptors: cloning of a third distinct subtype in the zebrafish

scientific article published in December 1997

Mutagenesis and computational modeling of human G-protein-coupled receptor Y2 for neuropeptide Y and peptide YY.

scientific article published on 31 October 2013

Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions

scientific article published on 13 May 2010

Mutational analysis of the Acropora millepora PaxD paired domain highlights the importance of the linker region for DNA binding

scientific article published in November 2003

Mutations and selection in the generation of class II histocompatibility antigen polymorphism

scientific article published on July 1984

Neuropeptide Y inhibits spontaneous alpha-melanocyte-stimulating hormone (alpha-MSH) release via a Y(5) receptor and suppresses thyrotropin-releasing hormone-induced alpha-MSH secretion via a Y(1) receptor in frog melanotrope cells

scientific article

Neuropeptide Y inhibits the biosynthesis of sulfated neurosteroids in the hypothalamus through activation of Y(1) receptors

scientific article published in May 2002

Neuropeptide Y receptor gene y6: multiple deaths or resurrections?

scientific article (publication date: 14 October 2000)

Neuropeptide Y receptor subtype with unique properties cloned in the zebrafish: the zYa receptor

scientific article published in July 1999

Neuropeptide Y-family peptides and receptors in the elephant shark, Callorhinchus milii confirm gene duplications before the gnathostome radiation

scientific article

Neuropeptide Y-family receptors Y6 and Y7 in chicken. Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region

scientific article published on May 2006

Neuropeptide Y/peptide YY receptor Y2 duplicate in zebrafish with unique introns displays distinct peptide binding properties

scientific article published on 10 August 2011

Neuropeptide role of both peptide YY and neuropeptide Y in vertebrates suggested by abundant expression of their mRNAs in a cyclostome brain

scientific article published in April 1994

Neuropeptide tyrosine in the rat adrenal gland--immunohistochemical and in situ hybridization studies

scientific article published on January 1988

Neuropeptide-Y gene expression in the goldfish brain: distribution and regulation by ovarian steroids

scientific article published on March 1994

New insights into the evolution of vertebrate CRH (corticotropin-releasing hormone) and invertebrate DH44 (diuretic hormone 44) receptors in metazoans

scientific article published on 16 September 2014

Novel neuropeptide Y Y2-like receptor subtype in zebrafish and frogs supports early vertebrate chromosome duplications

scientific article published in January 2004

One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology

scientific article

Origins of the many NPY-family receptors in mammals

scientific article published on 01 March 2001

Peptidergic neurons in the vertebrate spinal cord: evolutionary trends.

scientific article published on January 1995

Perturbation of the synaptic release machinery in hippocampal neurons by overexpression of SNAP-25 with the Semliki Forest virus vector

scientific article published in June 1999

Pharmacological characterization of cloned chicken neuropeptide Y receptors Y1 and Y5.

scientific article

Pharmacological characterization of ligand-receptor interactions at the zebrafish bradykinin receptor.

scientific article

Pharmacological comparison of rat and human melanocortin 3 and 4 receptors in vitro

scientific article

Phylogenetic and chromosomal analyses of multiple gene families syntenic with vertebrate Hox clusters

scientific article

Phylogenetic relationship of birds with crocodiles and mammals, as deduced from protein sequences

scientific article published on 01 November 1989

Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system

scientific article published on January 2003

Pufferfish and zebrafish have five distinct NPY receptor subtypes, but have lost appetite receptors Y1 and Y5.

scientific article

Rat beta-nerve growth factor sequence and site of synthesis in the adult hippocampus

scientific article

Ray-fin fish tetraploidization gave rise to pufferfish duplicates of NPY and PYY, but zebrafish NPY duplicate was lost

scientific article

Re-evaluation of receptor-ligand interactions of the human neuropeptide Y receptor Y1: a site-directed mutagenesis study

scientific article published on January 2006

Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig

scientific article published on April 2002

Reciprocal mutations of neuropeptide Y receptor Y2 in human and chicken identify amino acids important for antagonist binding

scientific article

Remarkable synteny conservation of melanocortin receptors in chicken, human, and other vertebrates ⬇️

scientific article published on May 1, 2003

Sequence of gene and cDNA encoding murine major histocompatibility complex class II gene A beta 2.

scientific article published in November 1985

Signal sequences distinguish class II histocompatibility antigen beta chains of different loci

scientific article published on 01 January 1984

Simplifying genetic locus assignment of HLA-DRB genes

scientific article published on February 1994

Site-directed mutagenesis of the 5-HT1B receptor increases the affinity of 5-HT for the agonist low-affinity conformation and reduces the intrinsic activity of 5-HT.

scientific article published in June 2001

Site-directed mutagenesis of the human 5-HT1B receptor

scientific article published in May 1998

Spontaneous insertions into cosmid vector: a warning

scientific article

Steroid biosynthesis within the frog brain: a model of neuroendocrine regulation

scientific article published on April 2009

Strong evolutionary conservation of neuropeptide Y: sequences of chicken, goldfish, and Torpedo marmorata DNA clones ⬇️

scientific article published on March 15, 1992

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.

scientific article published on 18 April 2018

Structure and expression of the rat neuropeptide Y gene

scientific article

Structure of C-terminal half of two H-2 antigens from cloned mRNA.

scientific article published in July 1981

Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes

scientific article

Structure of the murine immune response I-A beta locus: sequence of the I-A beta gene and an adjacent beta-chain second domain exon

scientific article published on August 1983

Studies of the human, rat, and guinea pig Y4 receptors using neuropeptide Y analogues and two distinct radioligands

scientific article published in March 2001

The cloned guinea pig neuropeptide Y receptor Y1 conforms to other mammalian Y1 receptors

scientific article

The cloned guinea pig pancreatic polypeptide receptor Y4 resembles more the human Y4 than does the rat Y4.

scientific article

The complete nucleotide sequence of the I-Eαdimmune response gene ⬇️

scientific article published on August 11, 1983

The evolution of neuroendocrine peptides

scientific article

The evolution of vertebrate somatostatin receptors and their gene regions involves extensive chromosomal rearrangements

scientific article

The gene encoding the human class II antigen-associated gamma chain is located on chromosome 5

scientific article published on 01 January 1984

The highly conserved synapse protein SNAP-25 displays sequence variability in the cockroach Leucophaea maderae

scientific article

The neuropeptide Y Y1 receptor selective radioligand, [125I][Leu31,Pro34]peptide YY, is also a high affinity radioligand for human pancreatic polypeptide 1 receptors

scientific article published on December 1996

The oxytocin/vasopressin receptor family has at least five members in the gnathostome lineage, inclucing two distinct V2 subtypes

scientific article

The receptor revolution--multiplicity of G-protein-coupled receptors.

scientific article published on January 1993

The vertebrate ancestral repertoire of visual opsins, transducin alpha subunits and oxytocin/vasopressin receptors was established by duplication of their shared genomic region in the two rounds of early vertebrate genome duplications

scientific article

Three neuropeptide Y receptor genes in the spiny dogfish, Squalus acanthias, support en bloc duplications in early vertebrate evolution

scientific article published on 30 May 2003

Transducin duplicates in the zebrafish retina and pineal complex: differential specialisation after the teleost tetraploidisation

scientific article published on 25 March 2015

Uneven evolutionary rates of bradykinin B1 and B2 receptors in vertebrate lineages

scientific article published on 10 March 2006

Unexpected multiplicity of QRFP receptors in early vertebrate evolution

scientific article published on 24 October 2014

Vertebrate genome evolution and the zebrafish gene map

scientific article published on 01 April 1998

XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors

scientific article

Y4 receptor in different species. Functional expression and binding

scientific article published in January 2000

Zebrafish genes for neuropeptide Y and peptide YY reveal origin by chromosome duplication from an ancestral gene linked to the homeobox cluster

scientific article published on 01 September 2000

[125I]Leu31, Pro34-PYY is a high affinity radioligand for rat PP1/Y4 and Y1 receptors: evidence for heterogeneity in pancreatic polypeptide receptors

scientific article published on January 1997

cDNA clone coding for part of a mouse H-2d major histocompatibility antigen

scientific article

cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure ⬇️

scientific article published on December 1, 1983

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