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List of works by Michael Levin

4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease

scientific article published in The Lancet

A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis

scientific article

A Rare Mutation in SPLUNC1 Affects Bacterial Adherence and Invasion in Meningococcal Disease

scientific article published on 01 July 2019

A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease

scientific article published on May 2016

A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease

scientific article published on 11 October 2011

A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease

scientific article

A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection

scientific article

A myocardial cytotoxic process is involved in the cardiac dysfunction of meningococcal septic shock

scientific article published on 01 August 2000

A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national Delphi process

scientific article published on 18 September 2020

A new scoring system derived from base excess and platelet count at presentation predicts mortality in paediatric meningococcal sepsis

scientific article published on 11 April 2013

A nucleic acid strand displacement system for the multiplexed detection of tuberculosis-specific mRNA using quantum dots

scientific article published on 18 April 2016

A proteomics-based method for identifying antigens within immune complexes

scientific article published on 23 December 2020

Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-gamma

scientific article published on 25 August 2005

Age dependence of in vitro survival of meningococci in whole blood during childhood

scientific article published in October 2003

Albumin: saint or sinner?

scientific article published on November 1998

Alteration in glycosaminoglycan metabolism and surface charge on human umbilical vein endothelial cells induced by cytokines, endotoxin and neutrophils

scientific article published on August 1, 1992

An improved endothelial barrier model to investigate dengue haemorrhagic fever

scientific article published on July 2002

Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness

scientific article

Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo.

scientific article published in September 2002

Anti-interferon auto-antibodies in autoimmune polyendocrinopathy syndrome type 1.

scientific article published in July 2006

Antibiotic choices for meningitis beyond the neonatal period ⬇️

scientific article published on February 1, 1992

Antibiotic treatment of suspected neonatal meningitis.

scientific article published on January 1991

Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility

scientific article

Assessment of the effect of candidate anti-inflammatory treatments on the interaction between meningococci and inflammatory cells in vitro in a whole blood model

scientific article published on 01 January 1996

Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series

scientific article

Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease

scientific article published in The Lancet

Authors' reply

scientific article published on 13 January 1996

Avoidable deficiencies in the delivery of health care to children with meningococcal disease.

scientific article

Bacterial meningitis and brain abscess

article

Biliary cirrhosis in a child with inherited interleukin-12 deficiency

scientific article published on 19 January 2008

Biomarker discovery in infectious diseases using SELDI.

scientific article

Biomarkers for the Discrimination of Acute Kawasaki Disease From Infections in Childhood

scientific article published on 22 July 2020

Biosynthetic homeostasis and resilience of the complement system in health and infectious disease

scientific article published on 29 June 2019

Cardiovascular status after Kawasaki disease in the UK.

scientific article

Changes in the interleukin-6/soluble interleukin-6 receptor axis in meningococcal septic shock

scientific article published on 01 August 2005

Characterization of a myocardial depressant factor in meningococcal septicemia

scientific article published in October 2002

Childhood Multisystem Inflammatory Syndrome - A New Challenge in the Pandemic

scientific article published on 29 June 2020

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function.

scientific article

Circulating aldosterone levels are unexpectedly low in children with acute meningococcal disease

scientific article published in March 2004

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

scientific article published on 08 June 2020

Clinical features of dominant and recessive interferon γ receptor 1 deficiencies

scientific article published in The Lancet

Coagulation abnormalities in dengue hemorrhagic Fever: serial investigations in 167 Vietnamese children with Dengue shock syndrome

scientific article published on 11 July 2002

Coagulation in severe sepsis: a central role for thrombomodulin and activated protein C.

scientific article

Cohort profile of the Biomarkers of Acute Serious Illness in Children (BASIC) study: a prospective multicentre cohort study in critically ill children

scientific article published on 8 November 2018

Common Genetic Variations Associated with the Persistence of Immunity following Childhood Immunization

scientific article published on 01 June 2019

Comparison of pandemic and seasonal influenza reveals higher mortality and increased prevalence of shock in children with severe h1n1/09 infection.

scientific article

Complement Factor H Levels Associate With Malaria Susceptibility and Severity

scholarly article by Anna E van Beek et al published July 2018 in Open Forum Infectious Diseases

Critical illness and amputation in meningococcal septicemia: is life worth saving?

scientific article published in September 2008

Defective antigen processing associated with familial disseminated mycobacteriosis

scientific article

Deficiency of prostacyclin production in meningococcal shock

scientific article published on November 1991

Degradation of glycosaminoglycans and fibronectin on endotoxin-stimulated endothelium by adherent neutrophils: relationship to CD11b/CD18 and L-selectin expression

scientific article published in April 1993

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

scientific article (publication date: October 2013)

Development and validation of a prediction model for invasive bacterial infections in febrile children at European Emergency Departments: MOFICHE, a prospective observational study

scientific article published on 18 November 2020

Diagnosis of Bacterial Infection Using a 2-Transcript Host RNA Signature in Febrile Infants 60 Days or Younger

scientific article published on April 2017

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature

article

Diagnosis of childhood tuberculosis and host RNA expression in Africa

scientific article published in May 2014

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children

scientific article published on August 2016

Disruption of vascular homeostasis in patients with Kawasaki disease: involvement of vascular endothelial growth factor and angiopoietins

scientific article published on January 2012

Dissecting Kawasaki disease: a state-of-the-art review

scientific article published on 27 June 2017

Dissecting interferon-induced transcriptional programs in human peripheral blood cells

scientific article

Disseminated intravascular coagulation and purpura fulminans secondary to infection

article

Diversity in the emergency care for febrile children in Europe: a questionnaire study

scientific article published on 27 June 2019

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

article

Effect of dispersion of vessel diameters and lengths in stochastic networks. II. Modeling of microvascular hematocrit distribution

scientific article published in March 1986

Effect of the Factor V Leiden mutation on the severity of meningococcal disease

scientific article (publication date: October 1999)

Effects of saline or albumin fluid bolus in resuscitation: evidence from re-analysis of the FEAST trial

scientific article published on 10 June 2019

Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids

scientific article

Emergency management of meningococcal disease

scientific article

Emergency management of meningococcal disease: eight years on.

scientific article published on April 2007

Enhanced anti-mycobacterial immunity in children with erythema nodosum and a positive tuberculin skin test

scientific article

Estimating parasite load dynamics to reveal novel resistance mechanisms to human malaria

article

Evaluation of Human Antimycobacterial Immunity Using Recombinant Reporter Mycobacteria

scientific article published on 15 August 2000

Evaluation of temperature-pulse centile charts in identifying serious bacterial illness: observational cohort study

scientific article

Evidence for a superantigen mediated process in Kawasaki disease

scientific article published on April 1995

Evidence for exclusion of a mutation in NRAMP as the cause of familial disseminated atypical mycobacterial infection in a Maltese kindred

scientific article

Experimental treatments of meningococcal sepsis

scientific article published on 01 June 1998

Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial

scientific article

Extensive Ethnic Variation and Linkage Disequilibrium at the Locus: Different Genetic Associations Revealed in Kawasaki Disease

scientific article published on 21 March 2019

Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients

scientific article published in January 2006

Familial disseminated atypical mycobacterial disease

scientific article published on 01 December 1994

Gamma interferon-based immunodiagnosis of tuberculosis: comparison between whole-blood and enzyme-linked immunospot methods

scientific article

Gastrointestinal perforation complicating meningococcal disease

scientific article published on 01 May 1995

Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated With Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities

scientific article

Genetic influence on cytokine production in meningococcal disease

scientific article published in The Lancet

Genetic polymorphisms in host response to meningococcal infection: the role of susceptibility and severity genes

scientific article published on 28 May 2009

Genetic susceptibility to infectious diseases

scientific article

Genetic susceptibility to tuberculosis

scientific article published on 01 September 1999

Genome-wide Association Studies in Infectious Diseases

scientific article published on 19 April 2016

Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease

scientific article

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease

article by Sonia Davila et al published 8 August 2010 in Nature Genetics

Genome-wide host RNA signatures of infectious diseases: discovery and clinical translation.

scientific article published on 16 September 2017

Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease

scientific article

Genomewide analysis of the host response to malaria in Kenyan children

scientific article published on 14 April 2005

Global gene expression profiling identifies new therapeutic targets in acute Kawasaki disease

scientific article published on 20 November 2014

HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease

scientific article published on 20 May 2019

Haplotypic diversity in human CEACAM genes: effects on susceptibility to meningococcal disease

scientific article published on 25 October 2007

Host Genetics and Susceptibility to Infection

article

Host RNA signatures for diagnostics: an example from paediatric tuberculosis in Africa

scientific article published on 26 September 2014

Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity.

scientific article published on February 2017

Human TBK1 is required for early autophagy induction upon HSV1 infection

article

Hypokalemia in children with severe falciparum malaria

scientific article published in January 2004

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease

scientific article published on 06 May 2019

Immunogenicity of a serogroup B meningococcal vaccine against multiple Neisseria meningitidis strains in infants.

scientific article

Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1.

scientific article

Increased excretion of urinary glycosaminoglycans in meningococcal septicemia and their relationship to proteinuria

scientific article published on 01 August 2000

Induction of human endothelial tissue factor expression by Neisseria meningitidis: the influence of bacterial killing and adherence to the endothelium.

scientific article

Infectious purpura fulminans: caution needed in the use of protein C.

scientific article published in July 1999

Inherited predisposition to mycobacterial infection: historical considerations

scientific article published in November 2000

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

scientific article published in June 2018

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

scholarly article published 25 September 2017

Interferon-gamma therapy in two patients with progressive chronic pulmonary aspergillosis

scientific article published in June 2006

Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease

scientific article published on 25 August 2011

Kawasaki Disease: The Role of Immune Complexes Revisited

scientific article published on 12 June 2019

Kawasaki disease

scientific article published on 01 February 1993

Kawasaki disease thirty years on ⬇️

scientific article published on February 1, 1998

Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research

scientific article (publication date: April 2002)

Kawasaki disease: recent advances

scientific article published on December 1991

Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study

scientific article published on 28 April 2018

Lifetime cardiovascular management of patients with previous Kawasaki disease

scientific article published on 16 December 2019

Lipocalin-2 is a Sensitive and Specific Marker of Bacterial Infection in Children

scientific article published on 01 May 2019

Management and prevention of meningococcal disease

scientific article published on 01 August 2000

Management of Children With Fever at Risk for Pediatric Sepsis: A Prospective Study in Pediatric Emergency Care

scientific article published on 17 September 2020

Management of Kawasaki disease

scientific article published on 25 October 2013

Management of severe malaria in children: proposed guidelines for the United Kingdom

scientific article

Matrix metalloproteinase haplotypes associated with coronary artery aneurysm formation in patients with Kawasaki disease

scientific article

Meningococcal disease due to W135: fresh public health concerns

scientific article published in January 2001

Meningococcal disease due to strain W135.

scientific article published in July 2001

Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions

scientific article published on 17 June 2019

Mortality after fluid bolus in African children with severe infection

scientific article published on 26 May 2011

Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS).

scientific article

Multisystem Inflammatory Syndrome in Children: An International Survey

scientific article published on 24 November 2020

Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival

scientific article

Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase

scientific article published in July 2011

Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies

scientific article

Novel human in vitro system for evaluating antimycobacterial vaccines

scientific article

Opa protein repertoires of disease-causing and carried meningococci

scientific article published on 28 May 2008

Parenteral penicillin for children with meningococcal disease before hospital admission: case-control study

scientific article

Pathophysiology of meningococcal meningitis and septicaemia

scientific article

Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases

scientific article

Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways

scientific journal article

Performance of the MGIT TBc Identification Test and Meta-Analysis of MPT64 Assays for Identification of the Mycobacterium tuberculosis Complex in Liquid Culture ⬇️

scientific article published on October 12, 2011

Phase III trials required to resolve clinical equipoise over optimal fluid management in children with severe malaria

scientific article published on 9 February 2007

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

scientific article published on 27 November 2019

Platelet and soluble CD40L in meningococcal sepsis.

scientific article

Polymorphic variation in TIRAP is not associated with susceptibility to childhood TB but may determine susceptibility to TBM in some ethnic groups

scientific article

Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations

scientific article

Potentially lethal bacterial infection associated with varicella zoster virus

scientific article published on August 1996

Pre-transfusion management of children with severe malarial anaemia: a randomised controlled trial of intravascular volume expansion

scientific article published in February 2005

Predicting IVIG resistance in UK Kawasaki disease

scientific article published on 10 February 2015

Predicting active tuberculosis progression by RNA analysis

scientific article published on 23 March 2016

Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score

scientific article published on 31 July 2015

Production of low-avidity antibody by infants after infection with serogroup B meningococci

scientific article published on 01 December 2000

Production of tissue factor by monocyte progenitor cells

scientific article published on 01 October 1994

Prospective Observational Study of Incidence and Preventable Burden of Childhood Tuberculosis, Kenya

scientific article published in March 2018

Psychiatric adjustment in adolescents with a history of chronic fatigue syndrome

scientific article published in December 1999

Putative vaccine antigens from Neisseria meningitidis recognized by serum antibodies of young children convalescing after meningococcal disease

scientific article published on 09 September 2004

Quantitative multiplex profiling of the complement system to diagnose complement-mediated diseases

scientific article published on 09 December 2020

Randomized trial of volume expansion with albumin or saline in children with severe malaria: preliminary evidence of albumin benefit

scientific article published on 25 January 2005

Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group

scientific article (publication date: 16 September 2000)

Reconstitution of antimycobacterial immune responses in HIV-infected children receiving HAART.

scientific article published in April 2006

Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery

scientific article

Reduction of chemokine secretion in response to mycobacteria in infliximab-treated patients

scientific article

Reduction of the anticoagulant activity of glycosaminoglycans on the surface of the vascular endothelium by endotoxin and neutrophils: evaluation by an amidolytic assay

scientific article published on September 15, 1992

Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility

scientific article

Respiratory Tract Infection Management and Antibiotic Prescription in Children: A Unique Study Comparing Three Levels of Healthcare in The Netherlands

scientific article published on 28 December 2020

Response to volume resuscitation in children with severe malaria

scientific article published in October 2003

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries

scientific article

Risk score to stratify children with suspected serious bacterial infection: observational cohort study

scientific article

Role of functional plasminogen-activator-inhibitor-1 4G/5G promoter polymorphism in susceptibility, severity, and outcome of meningococcal disease in Caucasian children*

scientific article published on 01 December 2003

Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock.

scientific article published on January 2004

Safety, pharmacokinetics, and pharmacodynamics of drotrecogin alfa (activated) in children with severe sepsis

scientific article published in January 2004

Secondary re-analysis of the FEAST trial - Authors' reply

scientific article published on 01 October 2019

Severe P. falciparum malaria in Kenyan children: evidence for hypovolaemia

scientific article

Size and charge characteristics of the protein leak in dengue shock syndrome

scientific article published on 19 July 2004

Steroids for Kawasaki disease: the devil is in the detail ⬇️

scientific article published on October 19, 2012

Streptococcus associated toxic shock

scientific article published on January 1992

Systemic complications associated with bacterial tracheitis

scientific article

The course of severe chronic fatigue syndrome in childhood

scientific article published in March 2000

The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule expression and endothelial injury by Neisseria meningitidis

scientific article published on 01 January 1996

The orthopaedic management of peripheral ischaemia in meningococcal septicaemia in children

scientific article

The role of healthcare delivery in the outcome of meningococcal disease in children: case-control study of fatal and non-fatal cases

scientific article

Transcriptomic Studies of Malaria: a Paradigm for Investigation of Systemic Host-Pathogen Interactions

scholarly article by Hyun Jae Lee et al published 1 June 2018 in Microbiology and Molecular Biology Reviews

Transcriptomic profiling in childhood H1N1/09 influenza reveals reduced expression of protein synthesis genes

scientific article published on 29 July 2013

Transforming growth factor-beta signaling pathway in patients with Kawasaki disease

scientific article

Translation of a Host Blood RNA Signature Distinguishing Bacterial From Viral Infection Into a Platform Suitable for Development as a Point-of-Care Test

scientific article published on 04 January 2021

Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing

scientific article published on 2 February 2006

Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity

scientific article published on 21 August 2019

Understanding immune protection against tuberculosis using RNA expression profiling

scientific article

Understanding the genetic basis of susceptibility to mycobacterial infection

scientific article

Unravelling the genetic basis of susceptibility to mycobacterial infection

scientific article published on January 1997

Unsuspected HIV infection presenting in first year of life

scientific article published on May 1995

Vaccines for prevention of meningococcal disease

scientific article

Variation in antibiotic prescription rates in febrile children presenting to emergency departments across Europe (MOFICHE): A multicentre observational study

scientific article published on 19 August 2020

Variation in hospital admission in febrile children evaluated at the Emergency Department (ED) in Europe: PERFORM, a multicentre prospective observational study

scientific article published on 07 January 2021

Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease

scientific article published in October 1996

Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial.

scientific article

WHO guidelines on fluid resuscitation in children: missing the FEAST data

scientific article

Whole-exome sequencing for the identification of rare variants in primary immunodeficiency genes in children with sepsis - a prospective population-based cohort study

scientific article published on 18 March 2020

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