List of works by Irene Cózar-Castellano

Central proliferation and neurogenesis is impaired in type 2 diabetes and prediabetes animal models

scientific article

Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease

scientific article

Chloro-Furanocembranolides from Leptogorgia sp. Improve Pancreatic Beta-Cell Proliferation.

scientific article

Cyclin C stimulates β-cell proliferation in rat and human pancreatic β-cells

scientific article

Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice.

scientific article published on 21 June 2013

Epoxypukalide induces proliferation and protects against cytokine-mediated apoptosis in primary cultures of pancreatic β-cells

scientific article

Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip

scientific article published on 01 January 2006

Genetic deficiency of apolipoprotein D in the mouse is associated with nonfasting hypertriglyceridemia and hyperinsulinemia.

scientific article published on 31 May 2011

Ghrelin's Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality.

scientific article published on 16 July 2015

Glucose and Fatty Acid Metabolism in Placental Explants From Pregnancies Complicated With Gestational Diabetes Mellitus

scientific article published on 9 December 2014

Growth factors and beta cell replication.

scientific article

Hepatocyte Growth Factor Gene Therapy for Pancreatic Islets in Diabetes: Reducing the Minimal Islet Transplant Mass Required in a Glucocorticoid-Free Rat Model of Allogeneic Portal Vein Islet Transplantation ⬇️

scientific article published on October 9, 2003

Hepatocyte growth factor gene therapy for islet transplantation

scientific article published on April 2004

Hepatocyte growth factor is elevated in amniotic fluid from obese women and regulates placental glucose and fatty acid metabolism.

scientific article

High glucose levels reduce fatty acid oxidation and increase triglyceride accumulation in human placenta.

scientific article published on 14 May 2013

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.

scientific article published on 13 March 2012

Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6

scientific article

Inhibition of fatty acid metabolism reduces human myeloma cells proliferation.

scientific article

Insulin degrading enzyme is up-regulated in pancreatic β cells by insulin treatment

scientific article published on 04 May 2018

Intestinal Fructose and Glucose Metabolism in Health and Disease

scientific article published on 29 December 2019

Leptolide Improves Insulin Resistance in Diet-Induced Obese Mice.

scientific article published on 15 September 2017

Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines

scientific article published on 23 July 2008

Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice

scientific article published on 08 August 2018

Low-density lipoprotein cholesterol suppresses apoptosis in human multiple myeloma cells.

scientific article published on 3 May 2011

Manipulation of Transmembrane Transport by Synthetic K+ Ionophore Depsipeptides and Its Implications in Glucose-Stimulated Insulin Secretion in β-Cells

scientific article published on 24 June 2019

Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance

scientific article published on 22 July 2020

Molecular engineering human hepatocytes into pancreatic beta cells for diabetes therapy.

scientific article

Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1.

scientific article

Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity

scientific article published on 03 September 2019

Protective effects of epoxypukalide on pancreatic β-cells and glucose metabolism in STZ-induced diabetic mice.

scientific article published on 25 September 2015

Targeted delivery of HGF to the skeletal muscle improves glucose homeostasis in diet-induced obese mice.

scientific article published on 27 October 2015

[The search for new autoantigens in Sjögren's syndrome]

scientific article published on 01 December 2005

Paulina is supported by:

About Paulina

Help