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List of works by Jesús San Miguel

1,25-dihydroxyvitamin D3 inhibits proliferation of human promyelocytic leukaemia (HL60) cells and induces monocyte-macrophage differentiation in HL60 and normal human bone marrow cells

scientific article published on 01 January 1983

11C-Methionine-PET in Multiple Myeloma: A Combined Study from Two Different Institutions

scientific article published on 23 July 2017

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

6q deletion in Waldenström macroglobulinemia is associated with features of adverse prognosis

scientific article published on 01 January 2007

A Next-Generation Sequencing Strategy for Evaluating the Most Common Genetic Abnormalities in Multiple Myeloma.

scientific article published on 15 November 2016

A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemia.

scientific article published on March 2009

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

scientific article published in January 2019

A monoclonal antibody GR2110 reactive with a P24 antigen present in a subgroup of acute lymphoid leukemias

scientific article published on 01 January 1985

A new method for the analysis of plasma cell DNA content in multiple myeloma samples using a CD38/propidium iodide double staining technique

scientific article published on 01 December 1994

A phase I/II dose-escalation study investigating all-oral ixazomib-melphalan-prednisone induction followed by single-agent ixazomib maintenance in transplant-ineligible newly diagnosed multiple myeloma

scientific article published on 28 June 2018

A phase II trial of lenalidomide, dexamethasone and cyclophosphamide for newly diagnosed patients with systemic immunoglobulin light chain amyloidosis.

scientific article published on 14 May 2015

A prospective PETHEMA study of tandem autologous transplantation versus autograft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma

scientific article published on 08 July 2008

A randomized multicentric study comparing alternating combination chemotherapy (VCMP/VBAP) and melphalan-prednisone in multiple myeloma

scientific article published on 01 June 1990

A randomized phase III study of carfilzomib vs low-dose corticosteroids with optional cyclophosphamide in relapsed and refractory multiple myeloma (FOCUS).

scientific article

A randomized study comparing the effect of GM-CSF and G-CSF on immune reconstitution after autologous bone marrow transplantation

scientific article published on 01 July 1996

A retrospective analysis of 3954 patients in phase 2/3 trials of bortezomib for the treatment of multiple myeloma: towards providing a benchmark for the cardiac safety profile of proteasome inhibition in multiple myeloma.

scientific article published on 3 May 2017

Abnormalities of peripheral blood T lymphocytes and natural killer cells in alcoholic hepatitis persist after a 3-month withdrawal period

scientific article published on 01 June 1997

Abnormalities on 1q and 7q are associated with poor outcome in sporadic Burkitt's lymphoma. A cytogenetic and comparative genomic hybridization study

scientific article published on 01 October 2003

Acute leukemia of hybrid phenotype: T lymphoid and myelomonocytic markers

scientific article published on 01 May 1985

Acute lymphoblastic leukemia (ALL): detection of minimal residual disease (MRD) at flow cytometry

scientific article published on 01 January 1994

Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial

Adult precursor B-ALL with BCR/ABL gene rearrangements displays a unique immunophenotype based on the pattern of CD10, CD34, CD13 and CD38 expresssion

scientific article published on 01 March 2001

Adverse event management in patients with relapsed and refractory multiple myeloma taking pomalidomide plus low-dose dexamethasone: A pooled analysis.

scientific article

Age and organ damage correlate with poor survival in myeloma patients: meta-analysis of 1435 individual patient data from 4 randomized trials

scientific article

Allogeneic Transplant with Reduced Intensity Conditioning Regimens may Overcome the Poor Prognosis of B-Cell Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Variable Heavy-Chain Gene and Chromosomal Abnormalities (11q- and 17p-)

article

Allogeneic peripheral blood cell transplantation for hypereosinophilic syndrome with myelofibrosis

scientific article published on 01 January 2000

Allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning: results of a prospective multicentre study.

scientific article published in December 2001

Allogeneic peripheral stem cell transplantation in a case of hereditary sideroblastic anaemia

scientific article published on 01 June 2000

Alpha interferon in the management of essential thrombocythaemia ⬇️

scientific article published on January 1, 1991

Alpha-interferon maintenance treatment is associated with improved survival after high-dose treatment and autologous stem cell transplantation in patients with multiple myeloma: a retrospective registry study from the European Group for Blood and Ma

scientific article published on 01 March 2001

Alternating mini-BEAM/ESHAP as salvage therapy for refractory non-Hodgkin's lymphomas

scientific article published on 01 February 1997

An abnormal CD34+ myeloid/CD34+ lymphoid ratio at the end of chemotherapy predicts relapse in patients with acute myeloid leukemia

scientific article published on 01 April 1999

Analysis of hematopoietic progenitor cells in patients with myelodysplastic syndromes according to their cytogenetic abnormalities

scientific article published on 01 November 2004

Analysis of incidence, risk factors and clinical outcome of thromboembolic and bleeding events in 431 allogeneic hematopoietic stem cell transplantation recipients

scientific article published on 16 August 2012

Analysis of renal impairment in MM-003, a phase III study of pomalidomide + low - dose dexamethasone versus high - dose dexamethasone in refractory or relapsed and refractory multiple myeloma

scientific article published on 14 April 2016

Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry.

scientific article

Analytical and clinical validation of a novel in-house deep-sequencing method for minimal residual disease monitoring in a phase II trial for multiple myeloma

scientific article published on 17 February 2017

Anti-PD1 associated fulminant myocarditis after a single pembrolizumab dose: the role of occult pre-existing autoimmunity.

scientific article published on 12 April 2018

Aortoduodenal fistula: gastrointestinal bleeding and polymicrobial sepsis

scientific article published on 01 December 1982

Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivo

scientific article

Application of self-quenched JH consensus primers for real-time quantitative PCR of IGH gene to minimal residual disease evaluation in multiple myeloma.

scientific article

Association between trisomy 8 and the immunophenotype of blast cells from acute leukemias secondary to a myelodysplastic syndrome or chronic myeloproliferative disorders

scientific article published on 01 May 1997

Authors' Response

scientific article published on 01 August 2015

Autologous peripheral blood stem cell transplantation for multiple myeloma: a report of 259 cases from the Spanish Registry. Spanish Registry for Transplant in MM (Grupo Español de Trasplante Hematopoyético-GETH) and PETHEMA.

scientific article

B-cell chronic lymphocytic leukaemia: prognostic value of the immunophenotype and the clinico-haematological features

scientific article published on 01 May 1989

BAALC is an important predictor of refractoriness to chemotherapy and poor survival in intermediate-risk acute myeloid leukemia (AML).

scientific article published on 27 November 2009

BEAM chemotherapy followed by autologous stem cell support in lymphoma patients: analysis of efficacy, toxicity and prognostic factors

scientific article published on 01 September 1997

BIOMED-1 Concerted Action report: Flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis and follow-up of T cell acute lymphoblastic leukemia (T-ALL)

scientific article published on 28 April 2000

BIOMED-1 concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings

scientific article published on 26 July 2001

Bendamustine, bortezomib and prednisone for the treatment of patients with newly diagnosed multiple myeloma: results of a prospective phase 2 Spanish/PETHEMA trial.

scientific article published on 24 April 2015

Benefit from autologous stem cell transplantation in primary refractory myeloma? Different outcomes in progressive versus stable disease

scientific article

Biphenotypic leukemia in treated Hodgkin's disease

scientific article

Bone marrow biopsy in myelodysplastic syndromes: morphological characteristics and contribution to the study of prognostic factors

scientific article published on 01 May 1990

Bone marrow mesenchymal stem cells chimerism after allogeneic hematopoietic transplantation

scientific article published on 01 January 2006

Bone marrow mesenchymal stem cells for improving hematopoietic function: an in vitro and in vivo model. Part 2: Effect on bone marrow microenvironment.

scientific article

Bone remodelation markers are useful in the management of monoclonal gammopathies

scientific article published on 01 January 2004

Bortezomib and thalidomide maintenance after stem cell transplantation for multiple myeloma: a PETHEMA/GEM trial

scientific article published on 23 January 2017

Bortezomib cumulative dose, efficacy, and tolerability with three different bortezomib-melphalan-prednisone regimens in previously untreated myeloma patients ineligible for high-dose therapy

scientific article

Bortezomib in multiple myeloma.

scientific article published on December 2007

Bortezomib just for induction or also for maintenance in myeloma patients with renal impairment?

scientific article published on January 2014

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

scientific article published in June 2005

Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study

scientific article published on 13 June 2006

Bortezomib, lenalidomide, and dexamethasone as induction therapy prior to autologous transplant in multiple myeloma

scientific article published on 01 October 2019

Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple m

scientific article published on 23 August 2010

Bortezomib, melphalan, prednisone (VMP) versus melphalan, prednisone, thalidomide (MPT) in elderly newly diagnosed multiple myeloma patients: A retrospective case-matched study

scientific article published on 05 February 2014

Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q- syndrome

scientific article published on 08 January 2009

C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma

scientific article published on 07 April 2014

CD117 expression in gammopathies is associated with an altered maturation of the myeloid and lymphoid hematopoietic cell compartments and favorable disease features

scientific article

CD34 + cell dose and outcome of patients undergoing reduced-intensity-conditioning allogeneic peripheral blood stem cell transplantation.

scientific article

Can CRd be a standard for refractory myeloma?

scientific article published in October 2013

Can multiple myeloma become a curable disease?

scientific article published in September 2011

Carfilzomib and pomalidomide in patients with relapsed and/or refractory multiple myeloma with baseline risk factors

scientific article

Carfilzomib in relapsed or refractory multiple myeloma patients with early or late relapse following prior therapy: A subgroup analysis of the randomized phase 3 ASPIRE and ENDEAVOR trials.

scientific article published on 15 February 2018

Carfilzomib or bortezomib with melphalan-prednisone for transplant-ineligible patients with newly diagnosed multiple myeloma

scientific article published on 28 February 2019

Carfilzomib, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma

article

Carfilzomib, lenalidomide, and dexamethasone in patients with relapsed multiple myeloma categorised by age: secondary analysis from the phase 3 ASPIRE study

scientific article

Carfilzomib-lenalidomide-dexamethasone vs lenalidomide-dexamethasone in relapsed multiple myeloma by previous treatment

scientific article

Cell cycle analysis of Waldenstrom's macroglobulinemia

scientific article published on 01 March 2005

Characterization of blast cells in chronic granulocytic leukaemia in transformation, acute myelofibrosis and undifferentiated leukaemia. I. Ultrastructural morphology and cytochemistry

scientific article published on 01 February 1985

Characterization of bone marrow T cells in monoclonal gammopathy of undetermined significance, multiple myeloma, and plasma cell leukemia demonstrates increased infiltration by cytotoxic/Th1 T cells demonstrating a squed TCR-Vbeta repertoire

scientific article published on 01 March 2006

Chimeric antigen receptor T-cell therapy for multiple myeloma: a consensus statement from The European Myeloma Network

scientific article published on 22 August 2019

Chimerism analysis following allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning.

scientific article published in March 2003

Chronic T cell lymphocytosis: a review of 21 cases.

scientific article

Cidofovir treatment of human polyomavirus-associated acute haemorrhagic cystitis.

scientific article published in March 2001

Circulating tumor cells for comprehensive and multiregional non-invasive genetic characterization of multiple myeloma

scientific article published on 01 June 2020

Clinical and immunological findings in large B-cell chronic lymphocytic leukemia

scientific article published on 01 February 1988

Clinical and prognostic value of discrepancies in microsatellite DNA regions between recipient and donor in human leukocyte antigen-identical allogeneic transplantation setting

scientific article published on 01 October 2008

Clinical applicability and prognostic significance of molecular response assessed by fluorescent-PCR of immunoglobulin genes in multiple myeloma. Results from a GEM/PETHEMA study.

scientific article

Clinicobiological, immunophenotypic, and molecular characteristics of monoclonal CD56-/+dim chronic natural killer cell large granular lymphocytosis

scientific article

Clinicopathological definition of Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia

scientific article

Clonal myelodysplastic cells present in apheresis product before transplantation

scientific article published on 01 September 1998

Clonal plasma cells from monoclonal gammopathy of undetermined significance, multiple myeloma and plasma cell leukemia show different expression profiles of molecules involved in the interaction with the immunological bone marrow microenvironment

scientific article published on 01 March 2005

Clonality analysis for antigen receptor genes: preliminary results from the Biomed-2 concerted action PL 96-3936.

scientific article

Combination of international scoring system 3, high lactate dehydrogenase, and t(4;14) and/or del(17p) identifies patients with multiple myeloma (MM) treated with front-line autologous stem-cell transplantation at high risk of early MM progression-r

scientific article

Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation

scientific article published on 01 January 2006

Comparison between a lyse-and-then-wash method and a lyse-non-wash technique for the enumeration of CD34+ hematopoietic progenitor cells

scientific article published on 01 December 1998

Comparison of immunofixation, serum free light chain, and immunophenotyping for response evaluation and prognostication in multiple myeloma

scientific article published on 14 March 2011

Comparison of next-generation sequencing (NGS) and next-generation flow (NGF) for minimal residual disease (MRD) assessment in multiple myeloma

scientific article published on 30 October 2020

Competition between clonal plasma cells and normal cells for potentially overlapping bone marrow niches is associated with a progressively altered cellular distribution in MGUS vs myeloma

article

Concluding remarks and future directions.

scientific article

Consensus Conference on Salvage Hematopoietic Cell Transplantation in Patients with Relapsed Multiple Myeloma (short title)

scientific article

Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2.

scientific article published on 03 February 2011

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3.

scientific article published on 03 February 2011

Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1.

scientific article published on 03 February 2011

Consolidation therapy in myeloma: a consolidated approach? ⬇️

scientific article published on 01 July 2012

Correlation of rhodamine 123 efflux by neoplastic plasma cells with clinical and biological characteristics of multiple myeloma

scientific article published on 01 February 1999

Current multiple myeloma treatment strategies with novel agents: a European perspective

scientific article published on 19 January 2010

Cytogenetic profiles in multiple myeloma and monoclonal gammopathy of undetermined significance: a study in highly purified aberrant plasma cells

scientific article published on 28 August 2012

Cytogenetics and long-term survival of patients with refractory or relapsed and refractory multiple myeloma treated with pomalidomide and low-dose dexamethasone.

scientific article

Cytokine therapy in multiple myeloma.

scientific article published on September 1996

DNA aneuploidy in acute myeloblastic leukemia is associated with a high expression of lymphoid markers

scientific article published on 01 March 1995

Daratumumab plus Bortezomib, Melphalan, and Prednisone for Untreated Myeloma

scientific article published on 12 December 2017

Daratumumab plus lenalidomide and dexamethasone in relapsed/refractory multiple myeloma: extended follow-up of POLLUX, a randomized, open-label, phase 3 study

scientific article published on 30 January 2020

Daratumumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX

scholarly article by Athanasios Dimopoulos et al published 20 September 2018 in Haematologica

Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma

scientific article

Daratumumab, lenalidomide, and dexamethasone in relapsed/refractory myeloma: a cytogenetic subgroup analysis of POLLUX

scientific article published on 03 November 2020

Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects

scientific article (publication date: 2012)

Debate round-table: comments concerning chimerism studies

scientific article published on 01 December 2001

Decreased natural killer cytotoxic activity in chronic alcoholism is associated with alcohol liver disease but not active ethanol consumption

scientific article published on 01 May 1997

Deficient spindle assembly checkpoint in multiple myeloma

scientific article

Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantation

scientific article published on 24 February 2004

Deletions and rearrangements of cyclin-dependent kinase 4 inhibitor gene p16 are associated with poor prognosis in B cell non-Hodgkin's lymphomas

scientific article published on 01 November 1997

Depth of Response in Multiple Myeloma: A Pooled Analysis of Three PETHEMA/GEM Clinical Trials

scientific article published on 12 May 2017

Deregulation of DNA double-strand break repair in multiple myeloma: implications for genome stability

scientific article

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.

scientific article

Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile

scientific article published on 26 September 2013

Detection of MYD88 L265P mutation by real-time allele-specific oligonucleotide polymerase chain reaction

scientific article published on 01 November 2014

Detection of abnormalities in B-cell differentiation pattern is a useful tool to predict relapse in precursor-B-ALL

scientific article published on 01 March 1999

Detection of monoclonality in bone marrow plasma cells by flow cytometry: limitations for minimal residual disease detection

scientific article published on 01 April 1996

Detection of the Mbcr/abl translocation in chronic myeloid leukemia by fluorescence in situ hybridization: comparison with conventional cytogenetics and implications for minimal residual disease detection

scientific article published on 01 February 1997

Development of acute leukaemia after idiopathic myelofibrosis ⬇️

scientific article published on May 1, 1992

Diagnosis of secondary myelodysplastic syndromes (MDS) following autologous transplantation should not be based only on morphological criteria used for diagnosis of de novo MDS

scientific article published on 01 May 1999

Differences in genetic changes between multiple myeloma and plasma cell leukemia demonstrated by comparative genomic hybridization

scientific article published on 01 May 2001

Differentiation stage of myeloma plasma cells: biological and clinical significance.

scientific article

Distribution of peripheral blood lymphoid subsets in alcoholic liver cirrhosis: influence of ethanol intake

scientific article published on 01 December 1996

Distribution of the CD45R antigen in the maturation of lymphoid and myeloid series: the CD45R negative phenotype is a constant finding in T CD4 positive lymphoproliferative disorders

scientific article published on 01 June 1988

Early immunophenotypical evaluation of minimal residual disease in acute myeloid leukemia identifies different patient risk groups and may contribute to postinduction treatment stratification

scientific article published on 01 September 2001

Early myeloma-related death in elderly patients: development of a clinical prognostic score and evaluation of response sustainability role

scientific article published on 23 February 2018

Early onset of chemotherapy can reduce the incidence of ATRA syndrome in newly diagnosed acute promyelocytic leukemia (APL) with low white blood cell counts: results from APL 93 trial

scientific article published on 01 February 2003

Effect of cumulative bortezomib dose on survival in multiple myeloma patients receiving bortezomib-melphalan-prednisone in the phase III VISTA study.

scientific article published on 27 February 2015

Effect of high altitude on protein metabolism in Bolivian children.

scientific article published in January 2002

Effect of vitamin D treatment in chronic GVHD

scientific article published on 17 January 2011

Effects of IL-8 Up-Regulation on Cell Survival and Osteoclastogenesis in Multiple Myeloma

scientific article published on 11 June 2016

Effects of Lenalidomide and Dexamethasone Treatment Duration on Survival in Patients With Relapsed or Refractory Multiple Myeloma Treated With Lenalidomide and Dexamethasone

article

Efficacy of bortezomib to intensify the conditioning regimen and the graft-versus-host disease prophylaxis for high-risk myeloma patients undergoing transplantation

scientific article published on 24 September 2019

Efficacy of darbepoetin alfa in alleviating fatigue and the effect of fatigue on quality of life in anemic patients with lymphoproliferative malignancies

scientific article published on 01 April 2006

Efficacy of rituximab in an aggressive form of multicentric Castleman disease associated with immune phenomena

scientific article published on 01 April 2005

Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma

scientific article published on 2 June 2015

Elotuzumab in combination with thalidomide and low-dose dexamethasone: a phase 2 single-arm safety study in patients with relapsed/refractory multiple myeloma

scientific article published on 19 July 2016

Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma

scientific article published on 01 November 2018

Elotuzumab plus lenalidomide/dexamethasone for relapsed or refractory multiple myeloma: ELOQUENT-2 follow-up and post-hoc analyses on progression-free survival and tumour growth

scientific article

Engineering Anti-myeloma Responses Using Affinity-Enhanced TCR-Engineered T Cells.

scientific article published on September 2015

Epigenetic regulation of PRAME in acute myeloid leukemia is different compared to CD34+ cells from healthy donors: Effect of 5-AZA treatment

scientific article published on 13 April 2012

Erratum to: Practical Considerations for the Use of Daratumumab, a Novel CD38 Monoclonal Antibody, in Myeloma

scientific article published on 20 May 2016

European perspective on multiple myeloma treatment strategies in 2014

scientific article

European perspective on multiple myeloma treatment strategies: update following recent congresses

scientific article

Evaluating gene expression profiling by quantitative polymerase chain reaction to develop a clinically feasible test for outcome prediction in multiple myeloma

scientific article

Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes.

scientific article published in September 2002

Evidence of long-term disease control with panobinostat maintenance in patients with relapsed multiple myeloma.

scientific article published on 20 March 2015

Expression of APO2.7, bcl-2 and bax apoptosis-associated proteins in CD34- bone marrow cell compartments from patients with myelodysplastic syndromes.

scientific article

Expression of Bcl-2 by human bone marrow mast cells and its overexpression in mast cell leukemia.

scientific article

Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity.

scientific article

Expression of lymphoid-associated antigens in mast cells: report of a case of systemic mast cell disease

scientific article published on 01 December 1995

Expression of the CD117 antigen (c-Kit) on normal and myelomatous plasma cells

scientific article published on 01 December 1996

Expression of the FMC7 antigen in cases of B-lymphoproliferative diseases

scientific article published on 01 September 1987

Expression of the c-kit (CD117) molecule in normal and malignant hematopoiesis

scientific article published on 01 August 1998

Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial

scientific article published on 09 August 2007

Factors that influence long-term hematopoietic function following autologous stem cell transplantation

scientific article published on 01 August 1999

Fewer bone disease events, improvement in bone remodeling, and evidence of bone healing with bortezomib plus melphalan-prednisone vs. melphalan-prednisone in the phase III VISTA trial in multiple myeloma

article

Filanesib in combination with pomalidomide and dexamethasone in refractory MM patients: safety and efficacy, and association with alpha 1-acid glycoprotein (AAG) levels. Phase Ib/II Pomdefil clinical trial conducted by the Spanish MM group

scientific article published on 05 June 2020

Final overall survival results of a randomized trial comparing bortezomib plus pegylated liposomal doxorubicin with bortezomib alone in patients with relapsed or refractory multiple myeloma.

scientific article

First-in-Human Phase I Study of ABBV-838, an Antibody-Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma

scientific article published on 22 January 2020

Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL

scientific article published on 01 March 1999

Flow cytometry for fast screening and automated risk assessment in systemic light-chain amyloidosis

scientific article published on 12 December 2018

Flow cytometry in the diagnosis of cancer ⬇️

scientific article published on January 1, 1995

Fluorescence in situ hybridization analysis of aneuploidization patterns in monoclonal gammopathy of undetermined significance versus multiple myeloma and plasma cell leukemia

scientific article published on 01 February 2003

Frequency of HLA-A, -B and -DRB1 specificities and haplotypic associations in the population of Castilla y León (northwest-central Spain).

scientific article published in October 2011

Functional class switch recombination may occur 'in vivo' in Waldenström macroglobulinaemia.

scientific article

Functional expression of MDR-1 in acute myeloid leukemia: correlation with the clinical-biological, immunophenotypical, and prognostic disease characteristics

scientific article published on 01 September 1997

Future directions of next-generation novel therapies, combination approaches, and the development of personalized medicine in myeloma.

scientific article published on 11 April 2011

GEM2005 trial update comparing VMP/VTP as induction in elderly multiple myeloma patients: do we still need alkylators?

scientific article published on 01 September 2014

Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia.

scientific article

Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals

scientific article

Gene rearrangement in acute non-lymphoblastic leukaemia: correlation with morphological and immunophenotypic characteristics of blast cells

scientific article published on 01 January 1995

Gene scanning of VDJH-amplified segments is a clinically relevant technique to detect contaminating tumor cells in the apheresis products of multiple myeloma patients undergoing autologous peripheral blood stem cell transplantation

scientific article published on 01 October 2001

Genetic Abnormalities and Patterns of Antigenic Expression in Multiple Myeloma

scientific article published on 01 May 2005

Genetic heterogeneity of BCR/ABL+ adult B-cell precursor acute lymphoblastic leukemia: impact on the clinical, biological and immunophenotypical disease characteristics

scientific article published on 01 May 2005

Genomic analysis of high-risk smoldering multiple myeloma.

scientific article published on 13 February 2012

Genomic profiling for clinical decision making in lymphoid neoplasms

Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report

scientific article

Graft vs. host disease and graft vs. myeloma effect after non-myeloablative allogeneic transplantation.

scientific article published in September 2004

Guidelines for determination of the number of prior lines of therapy in multiple myeloma.

scientific article published in August 2015

HLA specificities are related to development and prognosis of diffuse large B-cell lymphoma.

scientific article published on 10 July 2013

Health-Related Quality of Life Results From the Open-Label, Randomized, Phase III ASPIRE Trial Evaluating Carfilzomib, Lenalidomide, and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With Relapsed Multiple Myeloma.

scientific article published on 6 September 2016

Health-related quality of life from the MM-003 trial of pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed and/or refractory multiple myeloma

scientific article published on 25 November 2014

Health-related quality of life in elderly, newly diagnosed multiple myeloma patients treated with VMP vs. MP: results from the VISTA trial.

scientific article published on 7 May 2012

Helper/suppressor T-cell subpopulations in benign paraproteinaemia

scientific article published on 01 June 1983

Hematological, immunophenotypic, and cytogenetic characteristics of acute myeloblastic leukemia with trisomy 11

scientific article published on 01 July 2005

Heterogeneity of T cell lymphoblastic leukaemias.

scientific article published on August 1991

Heterogeneity of structural abnormalities in the 7q31.3∼q34 region in myeloid malignancies

scientific article published on 01 April 2004

High FOXO3a expression is associated with a poorer prognosis in AML with normal cytogenetics.

scientific article

High-dose therapy in diffuse large cell lymphoma: results and prognostic factors in 452 patients from the GEL-TAMO Spanish Cooperative Group.

scientific article

High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA.

scientific article published on 16 August 2005

High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma

scientific article published on 29 November 2011

High-sensitive immunophenotyping and DNA ploidy studies for the investigation of minimal residual disease in multiple myeloma

scientific article published on 01 October 1999

How deep is the myeloma iceberg?

scientific article published on 01 December 2018

How should we treat newly diagnosed multiple myeloma patients?

scientific article published on January 2013

How to manage neutropenia in multiple myeloma

scientific article published on 16 December 2011

How to treat a newly diagnosed young patient with multiple myeloma.

scientific article published on January 2009

Human Bone Marrow Stromal Cells Differentiate Into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice.

scientific article published on 18 February 2015

Human bone marrow mast cells from indolent systemic mast cell disease constitutively express increased amounts of the CD63 protein on their surface

scientific article published on 01 October 1998

Hybrid acute leukaemia

scientific article published on 01 September 1987

Hyperhomocysteinemia is a risk factor of recurrent coronary event in young patients irrespective to the MTHFR C677T polymorphism

scientific article published on 26 September 2006

Hypertriglyceridemia in patients with typhoid fever

scientific article published on 01 March 1983

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

scientific article published on 08 June 2018

Imatinib mesylate elicits positive clinical response in atypical chronic myeloid leukemia involving the platelet-derived growth factor receptor beta

scientific article published in October 2003

Immune status of high-risk smoldering multiple myeloma patients and its therapeutic modulation under LenDex: a longitudinal analysis.

scientific article published on 14 December 2015

Immunogenetic characterization of clonal plasma cells in systemic light-chain amyloidosis

scientific article published on 19 March 2020

Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma.

scientific article published on 18 July 2007

Immunoglobulin lambda chain gene rearrangement in a case of acute nonlymphoblastic leukemia

scientific article published on 01 March 1999

Immunoglobulin lambda isotype gene rearrangements in B cell malignancies

scientific article published on 01 January 2001

Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.

scientific article published on 3 November 2009

Immunophenotype of c-kit cells in normal human bone marrow: implications for the detection of minimal residual disease in AML

scientific article published on 01 February 1995

Immunophenotypic alterations of bone marrow myeloid cell compartments in multiple myeloma patients predict for myelodysplasia-associated cytogenetic alterations

scientific article published on 14 March 2014

Immunophenotypic analysis of Waldenstrom's macroglobulinemia

scientific article (publication date: April 2003)

Immunophenotypic and Cytogenetic Comparison of Waldenström's Macroglobulinemia with Splenic Marginal Zone Lymphoma

scientific article published on 01 March 2005

Immunophenotypic characterisation of acute leukaemia after polycythemia vera

scientific article

Immunophenotypic evaluation of the plasma cell compartment in multiple myeloma: a tool for comparing the efficacy of different treatment strategies and predicting outcome.

scientific article published in March 2002

Immunophenotypic heterogeneity of multiple myeloma: influence on the biology and clinical course of the disease. Castellano-Leones (Spain) Cooperative Group for the Study of Monoclonal Gammopathies

scientific article published on 01 February 1991

Immunophenotypical detection of minimal residual disease in acute leukemia.

scientific article

Immunophenotyping of plasma cells in multiple myeloma.

scientific article published in January 2005

Impact of genetic abnormalities on survival after allogeneic hematopoietic stem cell transplantation in multiple myeloma.

scientific article published on 17 April 2008

Impact of immunophenotype on prognosis of patients with myelodysplastic syndromes. Its value in patients without karyotypic abnormalities.

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Impact of prior treatment and depth of response on survival in MM-003, a randomized phase 3 study comparing pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed/refractory multiple myeloma.

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Improvement in Overall Survival With Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

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Improving overall survival and overcoming adverse prognosis in the treatment of cytogenetically high-risk multiple myeloma.

scientific article published on 19 November 2012

In leukapheresis products from non-Hodgkin's lymphoma patients, the immature hematopoietic progenitors show higher CD90 and CD34 antigenic expression

scientific article published on 01 October 2007

In leukemic hematopoiesis CD34 antigen does not have the same significance as it does normal hematopoiesis ⬇️

scientific article published on July 1, 1997

In vitro autonomous proliferation in ANLL: clinical and biological significance

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In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone.

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Incidence and clinicobiologic characteristics of leukemic B-cell chronic lymphoproliferative disorders with more than one B-cell clone

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Incidence of phenotypic aberrations in a series of 467 patients with B chronic lymphoproliferative disorders: basis for the design of specific four-color stainings to be used for minimal residual disease investigation

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Incomplete DJH rearrangements as a novel tumor target for minimal residual disease quantitation in multiple myeloma using real-time PCR.

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Incomplete DJH rearrangements of the IgH gene are frequent in multiple myeloma patients: immunobiological characteristics and clinical implications.

scientific article published in July 2003

Increased expression of CD56 and HLA/DR antigens in CD2+ cells from multiple myeloma patients

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Increased expression of natural-killer-associated and activation antigens in multiple myeloma

scientific article published on 01 February 1992

Individualizing treatment of patients with myeloma in the era of novel agents.

scientific article published on 21 April 2008

Influence of the different CD34+ and CD34- cell subsets infused on clinical outcome after non-myeloablative allogeneic peripheral blood transplantation from human leucocyte antigen-identical sibling donors

scientific article published on 01 October 2002

Influence of the intensity of the conditioning regimen on the characteristics of acute and chronic graft-versus-host disease after allogeneic transplantation

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Insights into epigenetic regulation of microRNA-155 expression in multiple myeloma

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Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse.

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Interferon and dexamethasone in multiple myeloma patients refractory to chemotherapy

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International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation

scientific article published on 29 March 2011

International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma

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International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation

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International Myeloma Working Group risk stratification model for smoldering multiple myeloma (SMM)

scientific article published on 16 October 2020

International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma

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International harmonization in performing and reporting minimal residual disease assessment in multiple myeloma trials

scientific article published on 11 August 2020

International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders

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Interpreting clinical trial data in multiple myeloma: translating findings to the real-world setting

scientific article published on 09 November 2018

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

scientific article published on 02 July 2013

Intravenous busulfan and melphalan as a conditioning regimen for autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: a matched comparison to a melphalan-only approach.

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Introduction to a series of reviews on multiple myeloma

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Inverse Probability of Censoring Weighted Analysis to Adjust the Treatment Effect on Overall Survival for Subsequent Therapy: A Case Study in a Clinical Trial in Multiple Myeloma.

scientific article published on 26 October 2014

Is immunotherapy here to stay in multiple myeloma?

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Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study

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Isolation and characterization of mesenchymal stromal cells from human degenerated nucleus pulposus: comparison with bone marrow mesenchymal stromal cells from the same subjects

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Ixazomib maintenance therapy in newly diagnosed multiple myeloma: An integrated analysis of four phase I/II studies

scientific article published on 08 May 2019

Ixazomib significantly prolongs progression-free survival in high-risk relapsed/refractory myeloma patients.

scientific article published on 20 October 2017

Kappa deleting element as an alternative molecular target for minimal residual disease assessment by real-time quantitative PCR in patients with multiple myeloma.

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Laparoscopic diagnosis of tuberculous ascites

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Lenalidomide in combination with dexamethasone at first relapse in comparison with its use as later salvage therapy in relapsed or refractory multiple myeloma.

scientific article published on 19 March 2009

Lenalidomide in combination with dexamethasone for the treatment of relapsed or refractory multiple myeloma

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Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma

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Light scatter characteristics of blast cells in acute myeloid leukaemia: association with morphology and immunophenotype ⬇️

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Limbus damage in ocular graft-versus-host disease

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Liver function tests and absolute lymphocyte count at day +100 are predictive factors for extensive and severe chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplant

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Long-term follow-up in patients treated with Mini-BEAM as salvage therapy for relapsed or refractory Hodgkin's disease.

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Long-term immune recovery of patients undergoing allogeneic stem cell transplantation: a comparison with their respective sibling donors

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Long-term reversibility of renal dysfunction associated to light chain deposition disease with bortezomib and dexamethasone and high dose therapy and autologous stem cell transplantation

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Long-term treatment results for acute megakaryoblastic leukaemia patients: a multicentre study

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Lymphoid subsets in acute myeloid leukemias: increased number of cells with NK phenotype and normal T-cell distribution

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Maintenance Treatment and Survival in Patients With Myeloma: A Systematic Review and Network Meta-analysis

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Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial

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Maintenance treatment with interferon alpha-2b in multiple myeloma: a prospective randomized study from PETHEMA (Program for the Study and Treatment of Hematological Malignancies, Spanish Society of Hematology).

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Management of multiple myeloma in the newly diagnosed patient.

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Management of patients with multiple myeloma in the era of COVID-19 pandemic: a consensus paper from the European Myeloma Network (EMN)

scientific article published on 22 May 2020

Management of smoldering myeloma: Recommendations of the Spanish Myeloma Group

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Measurable residual disease in multiple myeloma: ready for clinical practice?

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Mesenchymal stem cells are functionally abnormal in patients with immune thrombocytopenic purpura.

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Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival

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Methylenetetrahydrofolate reductase genotype does not play a role in multiple myeloma pathogenesis.

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Minimal number of circulating CD34+ cells to ensure successful leukapheresis and engraftment in autologous peripheral blood progenitor cell transplantation

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Minimal residual disease evaluation by flow cytometry is a complementary tool to cytogenetics for treatment decisions in acute myeloid leukaemia.

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Minimal residual disease in adolescent (older than 14 years) and adult acute lymphoblastic leukemias: early immunophenotypic evaluation has high clinical value.

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Minimal residual disease monitoring after allogeneic transplantation may help to individualize post-transplant therapeutic strategies in acute myeloid malignancies

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Minimal residual disease monitoring and immune profiling in multiple myeloma in elderly patients

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Minimal residual disease monitoring in multiple myeloma: a comparison between allelic-specific oligonucleotide real-time quantitative polymerase chain reaction and flow cytometry.

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Mobilisation with G-CSF in healthy donors promotes a high but temporal deregulation of genes

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Mobilization in myeloma revisited: IMWG consensus perspectives on stem cell collection following initial therapy with thalidomide-, lenalidomide-, or bortezomib-containing regimens

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Molecular biology of myeloma.

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Molecular characterization of complete and incomplete immunoglobulin heavy chain gene rearrangements in hairy cell leukemia

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Molecular characterization of heavy chain immunoglobulin gene rearrangements in Waldenström's macroglobulinemia and IgM monoclonal gammopathy of undetermined significance

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Molecular characterization of immunoglobulin gene rearrangements in diffuse large B-cell lymphoma: antigen-driven origin and IGHV4-34 as a particular subgroup of the non-GCB subtype.

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Monoclonal antibodies in the treatment of multiple myeloma: current status and future perspectives

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Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma

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Monoclonal gammopathy of undetermined significance: a consensus statement

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Monocyte counts: an early index of haemopoietic reconstitution after peripheral blood stem cell transplantation

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Multicolor fluorescence in situ hybridization studies in multiple myeloma and monoclonal gammopathy of undetermined significance.

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Multiparameter Flow Cytometry Evaluation of Plasma Cell DNA Content and Proliferation in 595 Transplant-Eligible Patients with Myeloma Included in the Spanish GEM2000 and GEM2005<65y Trials

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Multiparameter flow cytometry for staging of solitary bone plasmacytoma: new criteria for risk of progression to myeloma

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Multiparameter flow cytometry quantification of bone marrow plasma cells at diagnosis provides more prognostic information than morphological assessment in myeloma patients.

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Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality

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Multiple myeloma and chronic leukaemias in 2014: improved understanding of disease biology and treatment

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Multiple myeloma patients have a specific serum metabolomic profile that changes after achieving complete remission

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Multiple myeloma treatment strategies with novel agents in 2011: a European perspective

scientific article published on 26 March 2011

Multiple myeloma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

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Multiple myeloma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

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Multiple myeloma: a model for scientific and clinical progress

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Multiple myeloma: treatment evolution

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Multiple primary cutaneous plasmacytoma a decade after a nasal solitary extramedullary plasmacytoma: a puzzling case

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Myelodysplasia-associated immunophenotypic alterations of bone marrow cells in myeloma: are they present at diagnosis or are they induced by lenalidomide?

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Myelodysplastic syndrome evolving to a mixed myeloid-lymphoid leukaemia

scientific article published on 01 April 1986

Myelodysplastic syndromes

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MyelomA Genetics International Consortium

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Myeloma Cell Dynamics in Response to Treatment Supports a Model of Hierarchical Differentiation and Clonal Evolution.

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Myeloma in patients younger than age 50 years presents with more favorable features and shows better survival: an analysis of 10 549 patients from the International Myeloma Working Group

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New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings.

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Next Generation Flow for highly sensitive and standardized detection of minimal residual disease in multiple myeloma.

scientific article published on 20 January 2017

Novel agents derived from the currently approved treatments for MM: novel proteasome inhibitors and novel IMIDs.

scientific article published on 24 May 2012

Novel generation of agents with proven clinical activity in multiple myeloma.

scientific article published on October 2013

Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.

scientific article published in May 2001

Novel therapeutic agents for the management of patients with multiple myeloma and renal impairment.

scientific article published on 10 February 2012

Optimisation of mesenchymal stromal cells karyotyping analysis: implications for clinical use.

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Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification.

scientific article published on 12 May 2008

Oral beclomethasone dipropionate for the treatment of gastrointestinal acute graft-versus-host disease (GVHD).

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Origin of Waldenstrom's macroglobulinaemia

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Osteolytic lesion as the presenting feature of chronic granulocytic leukaemia

scientific article published on 01 January 1985

Outcome of childhood acute promyelocytic leukemia with all-trans-retinoic acid and chemotherapy.

scientific article published in April 2004

Overall survival of patients with relapsed multiple myeloma treated with panobinostat or placebo plus bortezomib and dexamethasone (the PANORAMA 1 trial): a randomised, placebo-controlled, phase 3 trial

scientific article published on 14 October 2016

Overall survival with daratumumab, bortezomib, melphalan, and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised, open-label, phase 3 trial

scientific article published on 10 December 2019

P53deletion may drive the clinical evolution and treatment response in multiple myeloma

scientific article published on 14 December 2009

PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma

scientific article published on 17 March 2015

Panobinostat as part of induction and maintenance for elderly patients with newly diagnosed acute myeloid leukemia: phase Ib/II panobidara study

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Panobinostat for the Treatment of Multiple Myeloma.

scientific article published on 11 September 2015

Panobinostat plus bortezomib and dexamethasone in previously treated multiple myeloma: outcomes by prior treatment

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Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial

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Panobinostat plus bortezomib and dexamethasone: impact of dose intensity and administration frequency on safety in the PANORAMA 1 trial.

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Panobinostat: a novel pan-deacetylase inhibitor for the treatment of relapsed or relapsed and refractory multiple myeloma

scientific article published on 07 June 2015

Pathologic rupture of the spleen during induction with ATRA in a patient with acute promyelocytic leukemia

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Patterns of BCR/ABL gene rearrangements by interphase fluorescence in situ hybridization (FISH) in BCR/ABL+ leukemias: incidence and underlying genetic abnormalities

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Peculiar cytogenetic finding in T-cell lymphoproliferative disorders

scientific article published on 01 June 1985

Pembrolizumab combined with lenalidomide and low-dose dexamethasone for relapsed or refractory multiple myeloma: phase I KEYNOTE-023 study

scientific article published on 15 May 2019

Pembrolizumab plus lenalidomide and dexamethasone for patients with treatment-naive multiple myeloma (KEYNOTE-185): a randomised, open-label, phase 3 trial

scientific article published on 18 July 2019

Pemetrexed acts as an antimyeloma agent by provoking cell cycle blockade and apoptosis.

scientific article published on 22 February 2007

Peripheral blood dendritic cell subsets from patients with monoclonal gammopathies show an abnormal distribution and are functionally impaired

scientific article published on 01 January 2008

Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN).

scientific article published on 12 August 2011

Perspectives on the Risk-Stratified Treatment of Multiple Myeloma

Phase 2 randomized study of bortezomib-melphalan-prednisone with or without siltuximab (anti-IL-6) in multiple myeloma

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Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia

scientific article published on 26 April 2011

Phase I/II study of weekly PM00104 (Zalypsis®) in patients with relapsed/refractory multiple myeloma.

scientific article

Phase II PETHEMA trial of alternating bortezomib and dexamethasone as induction regimen before autologous stem-cell transplantation in younger patients with multiple myeloma: efficacy and clinical implications of tumor response kinetics.

scientific article

Phase II clinical and pharmacokinetic study of plitidepsin 3-hour infusion every two weeks alone or with dexamethasone in relapsed and refractory multiple myeloma.

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Phase Ib study of panobinostat and bortezomib in relapsed or relapsed and refractory multiple myeloma.

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Phenotypic and genomic analysis of multiple myeloma minimal residual disease tumor cells: a new model to understand chemoresistance.

scientific article published on 11 January 2016

Phenotypic identification of subclones in multiple myeloma with different chemoresistant, cytogenetic and clonogenic potential

scientific article published on 12 November 2014

Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines

scientific article

Phenotypic, transcriptomic, and genomic features of clonal plasma cells in light-chain amyloidosis

scientific article published on 11 April 2016

Plasmablastic multiple myeloma: an immunologically different subtype

scientific article published on 01 June 1987

Pomalidomide and Low-Dose Dexamethasone Improves Health-Related Quality of Life and Prolongs Time to Worsening in Relapsed/Refractory Patients With Multiple Myeloma Enrolled in the MM-003 Randomized Phase III Trial

scientific article published on 6 June 2015

Pomalidomide plus low-dose dexamethasone in patients with relapsed/refractory multiple myeloma and moderate renal impairment: a pooled analysis of three clinical trials

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Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial

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Pomalidomide – An Appraisal of Its Clinical Development and Role in the Treatment of Relapsed/Refractory Multiple Myeloma

Pomalidomide, bortezomib, and dexamethasone for multiple myeloma previously treated with lenalidomide (OPTIMISMM): outcomes by prior treatment at first relapse

scientific article published on 07 September 2020

Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial

scientific article published on 13 May 2019

Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma

scientific article published on 4 September 2015

Post-treatment bone marrow residual disease > 5% by flow cytometry is highly predictive of short progression-free and overall survival in patients with Waldenström's macroglobulinemia

scientific article published on 01 February 2011

Posttransplant hematopoiesis in patients undergoing sibling allogeneic stem cell transplantation reflects that of their respective donors although with a lower functional capability.

scientific article published in August 2005

Practical Considerations for the Use of Daratumumab, a Novel CD38 Monoclonal Antibody, in Myeloma

scientific article published on 25 April 2016

Practical management of adverse events in multiple myeloma: can therapy be attenuated in older patients?

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Preclinical activity of the oral proteasome inhibitor MLN9708 in Myeloma bone disease.

scientific article published on 31 January 2014

Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair

scientific article published on 20 June 2017

Predicting long-term disease control in transplant-ineligible patients with multiple myeloma: impact of an MGUS-like signature

scientific article published on 18 March 2019

Prediction of peripheral neuropathy in multiple myeloma patients receiving bortezomib and thalidomide: a genetic study based on a single nucleotide polymorphism array.

scientific article published on 8 September 2016

Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network.

scientific article published on 2 May 2018

Prognostic Value of Immunophenotyping in Multiple Myeloma: A Study by the PETHEMA/GEM Cooperative Study Groups on Patients Uniformly Treated With High-Dose Therapy

scientific article published on 28 April 2008

Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated

scientific article published on 05 October 2006

Prognostic factors for donor lymphocyte infusions following non-myeloablative allogeneic stem cell transplantation in multiple myeloma.

scientific article published in June 2006

Prognostic factors of chronic graft-versus-host disease following allogeneic peripheral blood stem cell transplantation: the national institutes health scale plus the type of onset can predict survival rates and the duration of immunosuppressive the

scientific article published on 01 October 2008

Prognostic impact of pretransplantation computed tomography and gallium scans in patients with Hodgkin lymphoma with poor prognosis undergoing hematopoietic stem cell transplantation

scientific article published on 01 November 2006

Prognostic utility of serum free light chain ratios and heavy-light chain ratios in multiple myeloma in three PETHEMA/GEM phase III clinical trials

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Prognostic value of antigen expression in multiple myeloma: a PETHEMA/GEM study on 1265 patients enrolled in four consecutive clinical trials.

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Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma

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Prognostic value of immunophenotypic detection of minimal residual disease in acute lymphoblastic leukemia

scientific article published on 01 December 1998

Proliferative activity of plasma cells is the most relevant prognostic factor in elderly multiple myeloma patients

scientific article published on 01 December 2004

Quantitative analysis of bcl-2 expression in normal and leukemic human B-cell differentiation

scientific article published on 01 March 2004

RAF265, a dual BRAF and VEGFR2 inhibitor, prevents osteoclast formation and resorption. Therapeutic implications.

scientific article published on 7 July 2012

Randomized comparison of dexamethasone combined with melphalan versus melphalan with prednisone in the treatment of elderly patients with multiple myeloma.

scientific article published in October 2004

Recommendations for vaccination in multiple myeloma: a consensus of the European Myeloma Network

scientific article published on 19 August 2020

Redefining myeloma

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Reduced-intensity conditioning allogeneic blood stem cell transplantation with fludarabine and oral busulfan with or without pharmacokinetically targeted busulfan dosing in patients with myeloid leukemia ineligible for conventional conditioning.

scientific article published in June 2005

Reduced-intensity conditioning allogeneic transplantation is associated with a high incidence of extramedullary relapses in multiple myeloma patients

scientific article published on 01 March 2006

Reduced-intensity conditioning reduces the risk of severe infections after allogeneic peripheral blood stem cell transplantation

scientific article published on 01 August 2001

Relapse to prior autograft and chronic graft-versus-host disease are the strongest prognostic factors for outcome of melphalan/fludarabine-based dose-reduced allogeneic stem cell transplantation in patients with multiple myeloma.

scientific article published in October 2004

Relapse/Refractory myeloma patient: potential treatment guidelines.

scientific article published on 28 September 2009

Relevance of renin expression by real-time PCR in acute myeloid leukemia.

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Remarkable activity of novel agents bortezomib and thalidomide in patients not responding to donor lymphocyte infusions following nonmyeloablative allogeneic stem cell transplantation in multiple myeloma

scientific article published on 01 April 2006

Remission status defined by immunofixation vs. electrophoresis after autologous transplantation has a major impact on the outcome of multiple myeloma patients

scientific article published on 01 May 2000

Renal impairment in patients with multiple myeloma: a consensus statement on behalf of the International Myeloma Working Group

scientific article published on 18 October 2010

Reply to nowak et al

scientific article published on 01 September 2000

Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders

scientific article published on 11 February 2008

Response to Novel Drugs before and after Allogeneic Stem Cell Transplantation in Patients with Relapsed Multiple Myeloma

scientific article published on 03 May 2019

Reversibility of symptomatic peripheral neuropathy with bortezomib in the phase III APEX trial in relapsed multiple myeloma: impact of a dose-modification guideline

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Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group

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Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukemia

scientific article published on 21 February 2018

Risk factors for, and reversibility of, peripheral neuropathy associated with bortezomib-melphalan-prednisone in newly diagnosed patients with multiple myeloma: subanalysis of the phase 3 VISTA study.

scientific article published on 15 November 2010

Risk of progression in smouldering myeloma and monoclonal gammopathies of unknown significance: comparative analysis of the evolution of monoclonal component and multiparameter flow cytometry of bone marrow plasma cells

scientific article published on 11 October 2009

Risk stratification in the era of novel therapies.

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Role of 18F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International Myeloma Working Group

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Role of urine immunofixation in the complete response assessment of MM patients other than light-chain-only disease

scientific article published on 22 April 2019

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

scientific article published on 08 May 2012

Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma

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Second Revision of the International Staging System (R2-ISS) for Overall Survival in Multiple Myeloma: A European Myeloma Network (EMN) Report Within the HARMONY Project

scientific article published in 2022

Second primary malignancies in multiple myeloma: an overview and IMWG consensus

scientific article published on 01 April 2018

Sequential immunophenotypic analysis of mast cells in a case of systemic mast cell disease evolving to a mast cell leukemia

scientific article published on 01 April 1997

Sequential intravenous-oral ciprofloxacin plus amoxycillin/clavulanic acid shortens hospital stay in infected non severe neutropenic patients

scientific article published on 01 October 1997

Sequential vs alternating administration of VMP and Rd in elderly patients with newly diagnosed MM

scientific article published on 23 October 2015

Serum lactate dehydrogenase level as a prognostic factor in Hodgkin's disease.

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Short-term endothelial progenitor cell colonies are composed of monocytes and do not acquire endothelial markers

scientific article published on 01 January 2007

Should prophylactic granulocyte-colony stimulating factor be used in multiple myeloma patients developing neutropenia under lenalidomide-based therapy?

scientific article published on 7 December 2007

Simultaneous analysis of the expression of 14 genes with individual prognostic value in myelodysplastic syndrome patients at diagnosis: WT1 detection in peripheral blood adversely affects survival

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Skin involvement in non-secretory myeloma

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Smoldering multiple myeloma: when to observe and when to treat?

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Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple myeloma and their association with the characteristics of the disease

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Status of methylation of p16 gene in multiple myeloma: a comparative study of three methods for its detection

scientific article published on 01 July 2000

Subcutaneous delivery of daratumumab in relapsed or refractory multiple myeloma

scientific article published on 03 July 2019

Surface marker analysis in acute myeloid leukaemia and correlation with FAB classification.

scientific article published in November 1986

Survival of multiple myeloma patients who are potential candidates for early high-dose therapy intensification/ autotransplantation and who were conventionally treated

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Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone.

scientific article published on 18 August 2016

T cells subpopulations in untreated and treated patients with haemophilia A and B.

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T-cell subpopulations in patients with monoclonal gammopathies: essential monoclonal gammopathy, multiple myeloma, and Waldenstrom macroglobulinemia

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T-cell subsets and myeloma cell mass

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TCRalphabeta+/CD4+ large granular lymphocytosis: a new clonal T-cell lymphoproliferative disorder.

scientific article published on August 2003

Tandem transplants with different high-dose regimens improve the complete remission rates in multiple myeloma. Results of a Grupo Español de Síndromes Linfoproliferativos/Trasplante Autólogo de Médula Osea phase II trial.

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Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment.

scientific article published on 27 February 2017

Targeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development.

scientific article published on 20 October 2016

TdT activity in acute myeloid leukemias defined by monoclonal antibodies

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Thalidomide in combination with cyclophosphamide and dexamethasone (thacydex) is effective in soft-tissue plasmacytomas.

scientific article published in December 2002

The Andrés Laguna Master Lecture. Treatment of multiple myeloma

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The CD69 early activation molecule is overexpressed in human bone marrow mast cells from adults with indolent systemic mast cell disease

scientific article published on 01 August 1999

The DAC system and associations with multiple myeloma.

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The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee

The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma

scientific article published on 28 January 2019

The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.

scientific article published on April 2017

The Progression from MGUS to Smoldering Myeloma and Eventually to Multiple Myeloma Involves a Clonal Expansion of Genetically Abnormal Plasma Cells

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The Role of Panobinostat Plus Bortezomib and Dexamethasone in Treating Relapsed or Relapsed and Refractory Multiple Myeloma: A European Perspective

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The association of increased p14ARF/p16INK4a and p15INK4a gene expression with proliferative activity and the clinical course of multiple myeloma

scientific article published on 17 October 2006

The cellular origin and malignant transformation of Waldenström macroglobulinemia.

scientific article published on 5 February 2015

The clinical utility and prognostic value of multiparameter flow cytometry immunophenotyping in light-chain amyloidosis

scientific article published on 25 January 2011

The composition of leukapheresis products impacts on the hematopoietic recovery after autologous transplantation independently of the mobilization regimen

scientific article published on 01 September 2002

The detection of contaminating clonal cells in apheresis products is related to response and outcome in multiple myeloma undergoing autologous peripheral blood stem cell transplantation

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The effect of vitamin D3 metabolites on normal and leukemic bone marrow cells in vitro

scientific article published on 01 July 1984

The effects of different schedules of bortezomib, melphalan, and prednisone for patients with newly diagnosed multiple myeloma who are transplant ineligible: a matching-adjusted indirect comparison

scientific article published on 05 November 2019

The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects.

scientific article published on 05 July 2012

The histone deacetylase inhibitor LBH589 is a potent antimyeloma agent that overcomes drug resistance.

scientific article published on June 2006

The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells.

scientific article published on 12 March 2008

The investigational proteasome inhibitor ixazomib for the treatment of multiple myeloma.

scientific article published on January 2015

The nature of blast cells in myelodysplastic syndromes evolving to acute leukaemia

scientific article published on 01 June 1986

The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation.

scientific article

The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients

scientific article published on 15 September 2009

The phenotype of L-CFU and its correlation with the immunological characteristics of the blast cell population in AML

scientific article published on 01 May 1994

The predominant myeloma clone at diagnosis, CDR3 defined, is constantly detectable across all stages of disease evolution.

scientific article

The presence of DRB1*01 allele in multiple myeloma patients is associated with an indolent disease

scientific article published on 07 April 2008

The prognostic value of multiparameter flow cytometry minimal residual disease assessment in relapsed multiple myeloma.

scientific article published on 7 November 2014

The relationship between hyperthyroidism and the distribution of peripheral blood T, NK and B-lymphocytes in multinodular goiter

scientific article published on 01 February 1994

The research mission in myeloma

scientific article published on 07 August 2008

The role of immature platelet fraction in acute coronary syndrome

scientific article published on 13 November 2009

The use of CD138 positively selected marrow samples increases the applicability of minimal residual disease assessment by PCR in patients with multiple myeloma.

scientific article

Therapy-related acute promyelocytic leukemia.

scientific article published in June 2003

Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination

scientific article published on 08 October 2019

Transcriptome analysis reveals molecular profiles associated with evolving steps of monoclonal gammopathies.

scientific article

Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease

scientific article published on September 2014

Translocation (15;17)(q22;q21) in a patient with Klinefelter syndrome

scientific article published on 01 January 1996

Treatment for patients with newly diagnosed multiple myeloma in 2015.

scientific article published on 12 June 2015

Treatment of melphalan-resistant multiple myeloma with vincristine, BCNU, doxorubicin, and high-dose dexamethasone (VBAD)

scientific article published on January 1, 1992

Treatment of newly diagnosed myeloma in patients not eligible for transplantation.

scientific article published on June 2011

Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population.

scientific article published on 8 June 2009

Uptake and delivery of antigens by mesenchymal stromal cells.

scientific article published on 21 March 2013

Utility of flow cytometry studies in the management of patients with multiple myeloma.

scientific article published on 7 September 2016

V. Smoldering multiple myeloma

scientific article published on June 2015

VMP (Bortezomib, Melphalan, and Prednisone) is active and well tolerated in newly diagnosed patients with multiple myeloma with moderately impaired renal function, and results in reversal of renal impairment: cohort analysis of the phase III VISTA s

scientific article

Veno-occlusive disease of the liver after high-dose cytoreductive therapy with busulfan and melphalan for autologous blood stem cell transplantation in multiple myeloma patients.

scientific article published on December 2007

Vincristine is an effective therapeutic approach for transplantation-associated thrombotic microangiopathy

scientific article published on 01 February 2006

Weekly iron supplementation is as effective as 5 day per week iron supplementation in Bolivian school children living at high altitude

scientific article published on 01 June 1997

Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response.

scientific article published on 17 February 2011

Zoledronic acid as compared with observation in multiple myeloma patients at biochemical relapse: results of the randomized AZABACHE Spanish trial

scientific article published on 11 June 2015

[Guidelines for the use of bisphosphonates in multiple myeloma: Recommendations of the expert committee of the Spanish Myeloma Group from the PETHEMA group]

scientific article published on 28 October 2009

[Multiple myeloma]

scientific article published on 01 June 2007

[Value of serum free light chains assay in plasma cell disorders]

scientific article published on 03 July 2010

[Waldenström's disease with osteolytic lesions, renal failure and amyloidosis]

scientific article published on 01 April 2000

p16/INK4a gene inactivation by hypermethylation is associated with aggressive variants of monoclonal gammopathies

scientific article published on 01 January 2001

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