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List of works by Estela Castilla-Ortega

1-Oleoyl lysophosphatidic acid: a new mediator of emotional behavior in rats.

scientific article published on 7 January 2014

A place for the hippocampus in the cocaine addiction circuit: Potential roles for adult hippocampal neurogenesis

scientific article

Adult hippocampal neurogenesis as a target for cocaine addiction: a review of recent developments

scientific article published on 07 November 2019

Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice

scientific article

Alcohol-induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats

scientific article published on 12 September 2018

Behavioral phenotype of maLPA1-null mice: increased anxiety-like behavior and spatial memory deficits

scientific article

Both genetic deletion and pharmacological blockade of lysophosphatidic acid LPA1 receptor results in increased alcohol consumption.

scientific article published on 14 December 2015

Central administration of galanin N-terminal fragment 1-15 decreases the voluntary alcohol intake in rats.

scientific article published on 6 December 2017

Chronic immobilization in the malpar1 knockout mice increases oxidative stress in the hippocampus.

scientific article

Cocaine-conditioned place preference is predicted by previous anxiety-like behavior and is related to an increased number of neurons in the basolateral amygdala

scientific article

Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus

scientific article

Cocaine-induced changes in CX3CL1 and inflammatory signaling pathways in the hippocampus: Association with IL1β

scientific article published on 06 November 2019

Decreased plasma concentrations of BDNF and IGF-1 in abstinent patients with alcohol use disorders.

scientific article published on 6 November 2017

Effects of Intermittent Alcohol Exposure on Emotion and Cognition: A Potential Role for the Endogenous Cannabinoid System and Neuroinflammation.

scientific article

Effects of medial prefrontal cortex lesions on anxiety-like behaviour in restrained and non-restrained rats

scientific article published on 17 March 2009

Environmental enrichment as a therapeutic avenue for anxiety in aged Wistar rats: Effect on cat odor exposition and GABAergic interneurons.

scientific article published on 25 May 2016

Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor

scientific article published on 11 April 2010

Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors.

scientific article published on 18 June 2013

Higher Impulsivity As a Distinctive Trait of Severe Cocaine Addiction among Individuals Treated for Cocaine or Alcohol Use Disorders

scientific article published on 13 February 2018

Highlighting the Role of Cognitive and Brain Reserve in the Substance use Disorder Field

scientific article published on 01 January 2019

Hippocampal c-Fos activation in normal and LPA₁-null mice after two object recognition tasks with different memory demands.

scientific article published on 17 April 2012

How Healthy Is It to Fortify Cocoa-Based Products with Cocoa Flavanols? A Comprehensive Review

scientific article published in 2023

Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis

scientific article published on 30 January 2017

Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory.

scientific article published on 26 February 2018

Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation

scientific article published on 24 November 2018

Palmitoylethanolamide attenuates cocaine-induced behavioral sensitization and conditioned place preference in mice

scientific article published on 11 January 2018

Pharmacological blockade of either cannabinoid CB1 or CB2 receptors prevents both cocaine-induced conditioned locomotion and cocaine-induced reduction of cell proliferation in the hippocampus of adult male rat.

scientific article published on 08 January 2014

Pharmacological reduction of adult hippocampal neurogenesis modifies functional brain circuits in mice exposed to a cocaine conditioned place preference paradigm

scientific article

Plasma Chemokines in Patients with Alcohol Use Disorders: Association of CCL11 (Eotaxin-1) with Psychiatric Comorbidity

scientific article published on January 2016

Plasma concentrations of BDNF and IGF-1 in abstinent cocaine users with high prevalence of substance use disorders: relationship to psychiatric comorbidity

scientific article

Plasma concentrations of oleoylethanolamide and other acylethanolamides are altered in alcohol-dependent patients: effect of length of abstinence.

scientific article published on 22 May 2016

Reduced wheel running and blunted effects of voluntary exercise in LPA1-null mice: the importance of assessing the amount of running in transgenic mice studies

scientific article

Remote memory of drug experiences coexists with cognitive decline and abnormal adult neurogenesis in an animal model of cocaine-altered cognition

scientific article published on 23 February 2020

Serotonin is the main tryptophan metabolite associated with psychiatric comorbidity in abstinent cocaine-addicted patients

scientific article published on 14 November 2019

Sex differences in psychiatric comorbidity and plasma biomarkers for cocaine addiction in abstinent cocaine-addicted subjects in outpatient settings

scientific article

Stress, depression, resilience and ageing: A role for the LPA-LPA1 pathway.

scientific article

Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior.

scientific article published on 26 January 2018

The impact of cocaine on adult hippocampal neurogenesis: Potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction disorder

scientific article published on 05 May 2017

The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours

scientific article published on 31 January 2017

The presence of a social stimulus reduces cocaine-seeking in a place preference conditioning paradigm

scientific article published on 23 September 2019

Training memory without aversion: Appetitive hole-board spatial learning increases adult hippocampal neurogenesis

scientific article published on 31 March 2018

Voluntary exercise followed by chronic stress strikingly increases mature adult-born hippocampal neurons and prevents stress-induced deficits in 'what-when-where' memory

scientific article published on 11 December 2013

When is adult hippocampal neurogenesis necessary for learning? evidence from animal research.

scientific article published on 13 May 2011

Where to place the rewards? Exploration bias in mice influences performance in the classic hole-board spatial memory test

scientific article published on 09 March 2019

maLPA1-null mice as an endophenotype of anxious depression

scientific article

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