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List of works by Bruce C Verchere

Advances and challenges in islet transplantation: islet procurement rates and lessons learned from suboptimal islet transplantation.

scientific article published on 22 December 2011

Altered glutathione homeostasis in heart augments cardiac lipotoxicity associated with diet-induced obesity in mice.

scientific article published on 23 October 2011

Amyloid formation in human islets is enhanced by heparin and inhibited by heparinase

scientific article published on 01 April 2015

B7-H4 Induces Donor-Specific Tolerance in Mouse Islet Allografts ⬇️

scientific article published on September 16, 2011

CCL22 Prevents Rejection of Mouse Islet Allografts and Induces Donor-Specific Tolerance.

scientific article published in January 2015

Cellular mechanisms of CCL22-mediated attenuation of autoimmune diabetes

scientific article published on 04 March 2015

Cholesterol in beta-cell dysfunction: the emerging connection between HDL cholesterol and type 2 diabetes.

scientific article published on February 2010

Correction to: PAM haploinsufficiency does not accelerate the development of diet and human IAPP-induced diabetes in mice

scientific article published on 01 May 2020

Death and dysfunction of transplanted β-cells: lessons learned from type 2 diabetes?

scientific article

Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates

scientific article published on 19 January 2016

Elevated islet prohormone ratios as indicators of insulin dependency in auto‐islet transplant recipients

scientific article published in 2022

Endogenous expression of B7-H4 improves long-term murine islet allograft survival.

scientific article

Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?

scientific article published on 6 May 2016

HDL and LDL cholesterol significantly influence beta-cell function in type 2 diabetes mellitus.

scientific article published on June 2010

IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

scientific article

IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice

scientific article published on 10 December 2014

IL-33 Reverses an Obesity-Induced Deficit in Visceral Adipose Tissue ST2+ T Regulatory Cells and Ameliorates Adipose Tissue Inflammation and Insulin Resistance.

scientific article

Islet prohormone processing in health and disease

scientific article published on 01 September 2018

Islet remodeling in female mice with spontaneous autoimmune and streptozotocin-induced diabetes

scientific article

Kinetics and genomic profiling of adult human and mouse β-cell maturation ⬇️

scientific article published on July 1, 2011

Loss of Cyp8b1 improves glucose homeostasis by increasing GLP-1.

scientific article published on 22 October 2014

Myt3 suppression sensitizes islet cells to high glucose-induced cell death via Bim induction.

scientific article published on 19 May 2016

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice

scientific article published on 27 January 2020

Reawakening the Duct Cell Progenitor?

scientific article published in January 2016

Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction.

scientific article

Reverse engineering an amyloid aggregation pathway with dimensional analysis and scaling.

scientific article

Role of the TLR signaling molecule TRIF in β-cell function and glucose homeostasis.

scientific article published on March 2010

Selecting exercise regimens and strains to modify obesity and diabetes in rodents: an overview

scientific article published on 20 April 2010

T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression ⬇️

scientific article published on 8 February 2016

TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells ⬇️

scientific article published on July 6, 2012

The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.

scientific article

Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.

scientific article published on 13 March 2014

Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.

scientific article published on 23 May 2016

Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?

scientific article published on 25 February 2010

XIAP inhibition of β-cell apoptosis reduces the number of islets required to restore euglycemia in a syngeneic islet transplantation model.

scientific article published on January 2010

miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets.

scientific article published on 7 February 2012

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