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List of works by Gary S Coombs

Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer

scientific article

Binding of nonphysiological protein and peptide substrates to proteases: differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis.

scientific article published in May 2003

Carteriosulfonic acids A-C, GSK-3beta inhibitors from a Carteriospongia sp. ⬇️

scientific article published in September 2009

Catalytic Domain Structures of MT-SP1/Matriptase, a Matrix-degrading Transmembrane Serine Proteinase ⬇️

scientific article published on November 5, 2001

Directing sequence-specific proteolysis to new targets. The influence of loop size and target sequence on selective proteolysis by tissue-type plasminogen activator and urokinase-type plasminogen activator.

scientific article

Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator

scientific article published on 01 February 1996

Distinguishing the specificities of closely related proteases. Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase.

scientific article published on June 1997

Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.

scientific article published on 13 June 2011

Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation.

scientific article published on 2 March 2006

Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates

scientific article published on 01 June 2000

Optimal Subsite Occupancy and Design of a Selective Inhibitor of Urokinase ⬇️

scientific article published on August 15, 1997

Origins of the specificity of tissue-type plasminogen activator

scientific article

Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex

scientific article

Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives

scientific article

Substrate specificity of tissue type plasminogen activator. Characterization of the fibrin independent specificity of t-PA for plasminogen

scientific article published on 01 March 1995

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

scientific article

Wnt signaling in development, disease and translational medicine.

scientific article published on July 2008

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