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List of works by Julian Pardo

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

scientific article published on 21 December 2017

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

scientific article published in August 2001

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

scientific article published on 14 June 2009

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells.

scientific article published on 27 October 2016

Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression.

scientific article

All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity

scientific article published on 15 January 2014

Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.

scientific article published on 9 May 2018

Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein.

scientific article

Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

scientific article

Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis.

scientific article

Bis(methyl)gliotoxin proves to be a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis

scientific article published on 04 April 2012

Blinking effect and the use of quantum dots in single molecule spectroscopy.

scientific article published on 15 November 2012

CD56+/CD16- Natural Killer cells expressing the inflammatory protease granzyme A are enriched in synovial fluid from patients with osteoarthritis.

scientific article

Cell death induced by cytotoxic CD8+ T cells is immunogenic and primes caspase-3-dependent spread immunity against endogenous tumor antigens

scientific article published on 01 April 2020

Clinical validity of bis(methylthio)gliotoxin for the diagnosis of invasive aspergillosis

scientific article published on 17 December 2015

Course of Infection with the Emergent Pathogen Brucella microti in Immunocompromised Mice ⬇️

scientific article published on August 8, 2011

Cytotoxicity of quinone drugs on highly proliferative human leukemia T cells: Reactive oxygen species generation and inactive shortened SOD1 isoform implications ⬇️

scientific article published on May 16, 2012

Development and characterization of a microfluidic model of the tumour microenvironment

scientific article

Dissecting the molecular mechanism of apoptosis during photothermal therapy using gold nanoprisms.

scientific article published on 17 December 2014

Disseminated aspergillosis in an immunocompetent patient with detectable bis(methylthio)gliotoxin and negative galactomannan.

scientific article published on 8 December 2016

Down-regulation of normal human T cell blast activation: roles of APO2L/TRAIL, FasL, and c- FLIP, Bim, or Bcl-x isoform expression.

scientific article published on 14 January 2005

EMBO workshop on cytotoxicity, cell death and the immune system

scientific article published on 01 May 2009

ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

scientific article

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

scientific article published on 2 August 2013

Effect of Surface Chemistry and Associated Protein Corona on the Long-Term Biodegradation of Iron Oxide Nanoparticles In Vivo.

scientific article published on 12 January 2018

Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis

scientific article published on 10 July 2014

Essential complicity of perforin-granzyme and FAS-L mechanisms to achieve tumor rejection following treatment with anti-CD137 mAb

scientific article published on 29 May 2013

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

scientific article published on 14 June 2018

FRET based quantification and screening technology platform for the interactions of leukocyte function-associated antigen-1 (LFA-1) with intercellular adhesion molecule-1 (ICAM-1).

scientific article

Granulysin induces apoptotic cell death and cleavage of the autophagy regulator Atg5 in human hematological tumors.

scientific article

Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis.

scientific article published on 6 September 2016

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

scientific article

Granzyme A Is Required for Regulatory T-Cell Mediated Prevention of Gastrointestinal Graft-versus-Host Disease

scientific article published on 30 April 2015

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

scientific article

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

scientific article

Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Herpesvirus saimiri-transformed CD8+ T cells as a tool to study Chediak-Higashi syndrome cytolytic lymphocytes.

scientific article published on 22 February 2005

How Do Cytotoxic Lymphocytes Kill Cancer Cells?

scientific article

Human CD8+ T cell blasts are more sensitive than CD4+ T cell blasts to regulation by APO2L/TRAIL

scientific article published on 01 June 2005

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

scientific article published on 9 January 2015

Human and mouse granzyme A induce a proinflammatory cytokine response.

scientific article published on 23 October 2008

Immunoproteomic identification and characterization of Ni2+-regulated proteins implicates Ni2+ in the induction of monocyte cell death.

scientific article

In memoriam: Prof Christopher J Froelich (1951-2015)

scientific article published on January 2016

In vitro fungicidal photodynamic effect of hypericin on Trichophyton spp

scientific article published on 17 August 2014

Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo

scientific article published on 24 August 2016

Intestinal Serotonin Transporter Inhibition by Toll-Like Receptor 2 Activation. A Feedback Modulation

scientific article

Liposomes Decorated with Apo2L/TRAIL Overcome Chemoresistance of Human Hematologic Tumor Cells ⬇️

scientific article published on February 6, 2013

Lung metastases share common immune features regardless of primary tumor origin

scientific article published on 01 June 2020

MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis

scientific article published on 20 January 2011

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

scientific article

Marine Mammal Brucella Reference Strains Are Attenuated in a BALB/c Mouse Model.

scientific article

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion

scientific article

Mouse granzyme K has pro-inflammatory potential.

scientific article published on 11 February 2011

Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo.

scientific article published on 26 October 2017

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

scientific article published on 20 August 2010

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.

scientific article

Perforin rapidly induces plasma membrane phospholipid flip-flop

scientific article

Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis.

scientific article

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity ⬇️

scientific article published on July 5, 2012

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

scientific article published in February 2009

Protein oligomerization mediated by the transmembrane carboxyl terminal domain of Bcl-XL

scientific article

Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus.

scientific article

Second meeting of the Spanish Immunotherapy Group GEIT (Grupo Español de Inmunoterapia), January 16, 2015, in Zaragoza, Spain

scientific article published on 16 June 2015

Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner

scientific article published on December 2013

Serine protease inhibition attenuates rIL-12-induced GZMA activity and proinflammatory events by modulating the Th2 profile from estrogen-treated mice.

scientific article

The Untold Story of Granzymes in Oncoimmunology: Novel Opportunities with Old Acquaintances.

scientific article

The effect of acidic pH on the inhibitory efficacy of peptides against the interaction ICAM-1/LFA-1 studied by surface plasmon resonance (SPR).

scientific article published on 16 January 2014

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

scientific journal article

The new strains Brucella inopinata BO1 and Brucella species 83-210 behave biologically like classic infectious Brucella species and cause death in murine models of infection.

scientific article published on 20 February 2014

Toll-Like Receptors 2 and 4 Cooperate in the Control of the Emerging Pathogen Brucella microti

scientific article (publication date: 2016)

Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors.

scientific article published on 10 June 2016

Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon.

scientific article

Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved.

scientific article published on 5 June 2015

Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis.

scientific article

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