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List of works by Antonella Naldini

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

scientific article published on 8 October 2010

A ribonuclease protection assay-based approach for analysis of angiogenic gene expression in archival tissues.

scientific article published on September 2007

Analysis of protease-activated receptor-1 and -2 in human scar formation.

scientific article

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

scientific article

Early response to bleomycin is characterized by different cytokine and cytokine receptor profiles in lungs.

scientific article published on 20 August 2004

Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma

scientific article published on 01 June 2005

Human alpha-thrombin stimulates proliferation of interferon-gamma differentiated, growth-arrested U937 cells, overcoming differentiation-related changes in expression of p21CIP1/WAF1 and cyclin D1

scientific article published on 01 June 2002

Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes

scientific article published on 30 January 2019

Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1α and lipopolysaccharide.

scientific article published in February 2012

Hypoxia influences the cellular cross-talk of human dermal fibroblasts. A proteomic approach

scientific article published on 22 August 2007

Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells

scientific article

Identification of thrombin-like activity in ovarian cancer associated ascites and modulation of multiple cytokine networks

scientific article published on 11 August 2011

In vitro cytokine production and T-cell proliferation in patients undergoing cardiopulmonary by-pass

scientific article published on 01 February 1995

Inducible nitric oxide synthase activity correlates with lymphangiogenesis and vascular endothelial growth factor-C expression in head and neck squamous cell carcinoma.

scientific article published on February 2006

Inhibition of Bcr-Abl phosphorylation and induction of apoptosis by pyrazolo[3,4-d]pyrimidines in human leukemia cells

scientific article published on March 2007

Inhibition of smoothened in breast cancer cells reduces CAXII expression and cell migration

scientific article published on 21 August 2018

Interleukin 10 production in patients undergoing cardiopulmonary bypass: evidence of inhibition of Th-1-type responses

scientific article published on 01 January 1999

Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.

scientific article published on 26 August 2010

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a scaffold for the synthesis of inhibitors of Bcr-Abl.

scientific article published on 30 August 2011

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation.

scientific article published on May 2004

Plasma levels of immunosuppressive mediators during cardiopulmonary bypass.

scientific article published in January 1996

Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism

scientific article

Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype

scientific article

Protease-activated receptor-2 downregulation is associated to vitiligo lesions

scientific article published on 6 March 2009

Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.

scientific article published on March 2006

Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.

scientific article published on March 2004

Regulation of angiogenesis by Th1- and Th2-type cytokines.

scientific article

Role of inflammatory mediators in angiogenesis.

scientific article

Role of the hypoxic microenvironment in the antitumor activity of tyrosine kinase inhibitors.

scientific article published on January 2011

Short-term hypoxia enhances the migratory capability of dendritic cell through HIF-1α and PI3K/Akt pathway

scientific article published in December 2014

Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines.

scientific article published on 8 February 2008

Studies on tumor necrosis factor (TNF)—I. Pharmacokinetics of human recombinant TNF in rabbits and monkeys after intravenous administration

scientific article published on 01 January 1987

The Shc protein RAI promotes an adaptive cell survival program in hypoxic neuroblastoma cells.

scientific article

The Shc protein Rai enhances T-cell survival under hypoxia

scientific article published on 15 January 2020

The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells

scientific article published on 04 November 2009

The effects of autologous platelet gel on inflammatory cytokine response in human peripheral blood mononuclear cells

scientific article published on 01 June 2008

The lymphatic route. 1) Albumin and hyaluronidase modify the normal distribution of interferon in lymph and plasma

scientific article published on 01 April 1986

The lymphatic route. VIII. Distribution and plasma clearance of recombinant human interleukin-2 after SC administration with albumin in patients

scientific article published on 01 January 1993

The lymphatic route—II. Pharmacokinetics of human recombinant interferon-α2 injected with albumin as a retarder in rabbits

scientific article published on 01 January 1986

The lymphatic route—III. Pharmacokinetics of human natural interferon-β injected with albumin as a retarder in rabbits

scientific article published on 01 January 1986

The thrombin peptide, TP508, enhances cytokine release and activates signaling events

scientific article published on 01 November 2004

Thrombin Enhances T Cell Proliferative Responses and Cytokine Production

article

Thrombin Inhibits IFN-γ Production in Human Peripheral Blood Mononuclear Cells by Promoting a Th2 Profile

scientific article published on 01 November 2006

Thrombin enhancement of interleukin-1 expression in mononuclear cells: involvement of proteinase-activated receptor-1

scientific article published on 01 December 2002

Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation

scientific article published on 01 October 1998

Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1

scientific article published on 01 November 2000

p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.

scientific article published on February 2004

p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells

scientific article published on 01 May 2007

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