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List of works by Joana Dias Amaral

A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation

scientific article published on 31 January 2019

Ablation of RIP3 protects from dopaminergic neurodegeneration in experimental Parkinson's disease

scientific article published on 05 November 2019

Activation of necroptosis in human and experimental cholestasis.

scientific article published on 29 September 2016

Adaptation to carbon starvation: RNase III ensures normal expression levels of bolA1p mRNA and sigma(S).

scientific article published on 10 October 2005

Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset.

scientific article published on 28 September 2014

Bile acids: regulation of apoptosis by ursodeoxycholic acid

scientific article

Circulating Inflammatory miRNAs Associated with Parkinson's Disease Pathophysiology

scientific article published on 23 June 2020

Copper complex nanoformulations featuring highly promising therapeutic potential in murine melanoma models

scientific article published on 15 March 2019

Corrigendum: A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation

scientific article published on 24 April 2019

Development and Mechanistic Insight into the Enhanced Cytotoxic Potential of Parvifloron D Albumin Nanoparticles in EGFR-Overexpressing Pancreatic Cancer Cells

scientific article published on 05 November 2019

Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes

scientific article published on 12 April 2007

Discovery of a Necroptosis Inhibitor Improving Dopaminergic Neuronal Loss after MPTP Exposure in Mice

journal article from 'International Journal of Molecular Sciences' published in 2021

Efficient recovery of proteins from multiple source samples after TRIzol(®) or TRIzol(®)LS RNA extraction and long-term storage.

scientific article

Function of nuclear steroid receptors in apoptosis: role of ursodeoxycholic acid

scientific article published on 01 July 2007

Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid beta-peptide-induced apoptosis.

scientific article published on 25 May 2006

Impaired cytoprotective function of muscle in human gallbladders with cholesterol stones

scientific article published on 14 October 2004

In vitro targeting of colon cancer cells using spiropyrazoline oxindoles.

scientific article

Live-cell imaging of p53 interactions using a novel Venus-based bimolecular fluorescence complementation system

scientific article

Loss of Microglial Parkin Inhibits Necroptosis and Contributes to Neuroinflammation

scientific article published on 03 August 2018

Mechanism and disease implications of necroptosis and neuronal inflammation

scientific article published on 05 September 2018

Modulation of hepatocyte apoptosis: cross-talk between bile acids and nuclear steroid receptors.

scientific article published on January 2006

Molecular mechanisms of necroptosis and relevance for neurodegenerative diseases

scientific article published on 13 February 2020

N-acetylcysteine treatment attenuates the cognitive impairment and synaptic plasticity loss induced by streptozotocin.

scientific article published on 9 May 2017

No evidence of direct binding between ursodeoxycholic acid and the p53 DNA-binding domain

scientific article published on 3 June 2010

Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta1-induced apoptosis in rat hepatocytes

scientific journal article

Phenotypic screening identifies a new oxazolone inhibitor of necroptosis and neuroinflammation

scientific article published on 10 July 2018

Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus: Seasonal changes

scientific article published on 06 March 2006

Role of nuclear steroid receptors in apoptosis.

scientific article published on January 2009

Spirooxadiazoline oxindoles with promising in vitro antitumor activities

Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties

scientific article published on 21 September 2017

Synthesis and evaluation of spiroisoxazoline oxindoles as anticancer agents

scientific article published on 7 November 2013

TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice.

scientific article published on 23 March 2012

Targeting the p53 pathway of apoptosis.

scientific article published on January 2010

Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice.

scientific article published on 22 May 2012

Ursodeoxycholic acid modulates the ubiquitin-proteasome degradation pathway of p53.

scientific article published on 31 August 2010

p53 and the regulation of hepatocyte apoptosis: implications for disease pathogenesis.

scientific article published on 12 October 2009

p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis

scientific journal article