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List of works by Olivier Kosmider

A G polymorphism in the CRBN gene acts as a biomarker of response to treatment with lenalidomide in low/int-1 risk MDS without del(5q).

scientific article published on 26 February 2013

A common alternative splicing signature is associated with SF3B1 mutations in malignancies from different cell lineages.

scientific article

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

scientific article published on 01 July 2019

APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

scientific article published on 18 February 2016

ASXL1 and SETBP1 mutations and their prognostic contribution in chronic myelomonocytic leukemia: a two-center study of 466 patients.

scientific article published on 3 April 2014

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

scientific article published on 28 October 2009

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

scientific article

Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid leukemias

scientific article published on 27 August 2009

Architectural and functional heterogeneity of hematopoietic stem/progenitor cells in non-del(5q) myelodysplastic syndromes.

scientific article published on 16 November 2016

Are somatic mutations predictive of response to erythropoiesis stimulating agents in lower risk myelodysplastic syndromes?

scientific article published on 7 April 2016

Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study.

scientific article published on 30 July 2018

BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders.

scientific article

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia

scientific article published on 20 March 2019

Chronic myelomonocytic leukemia in younger patients: molecular and cytogenetic predictors of survival and treatment outcome

scientific article

Chronic myelomonocytic leukemia in younger patients: molecular and cytogenetic predictors of survival and treatment outcome

scientific article published on 13 February 2015

Clonal architecture of chronic myelomonocytic leukemias

scientific article published on 14 January 2013

Cotargeting signaling pathways driving survival and cell cycle circumvents resistance to Kit inhibitors in leukemia ⬇️

scientific article published on March 20, 2012

Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes.

scientific article published on 12 December 2011

Dyserythropoiesis of myelodysplastic syndromes

scientific article published on 7 January 2017

Effect of lenalidomide treatment on clonal architecture of myelodysplastic syndromes without 5q deletion

scientific article published on December 2015

Efficacy of 5-Azacytidine in aTET2mutated angioimmunoblastic T cell lymphoma

scientific article published on 14 October 2014

Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinase

scientific article

Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine.

scientific article

Flow cytometric detection of dyserythropoiesis: a sensitive and powerful diagnostic tool for myelodysplastic syndromes.

scientific article

From mice to human: the "two-hit model" of leukemogenesis

scientific article

Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia

scientific article published on 19 October 2010

Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias

scientific article published on 15 April 2011

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

scientific article published on 03 August 2020

Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission.

scientific article published on 20 May 2010

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

scientific article published on 06 September 2013

Kit-activating mutations cooperate with Spi-1/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice.

scientific article published on December 2005

Lenalidomide with or without erythropoietin in transfusion-dependent erythropoiesis-stimulating agent-refractory lower-risk MDS without 5q deletion.

scientific article published on 26 October 2015

Leukemic phase of follicular lymphomas: an atypical presentation.

scientific article published on 17 May 2011

Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

scientific article published on 12 November 2012

Molecular and prognostic correlates of cytogenetic abnormalities in chronic myelomonocytic leukemia: a Mayo Clinic-French Consortium Study.

scientific article published on 26 September 2014

Mutation of the colony-stimulating factor-3 receptor gene is a rare event with poor prognosis in chronic myelomonocytic leukemia.

scientific article published on 18 June 2013

Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes.

scientific article

Mutations des gènes impliqués dans l’épissage dans les hémopathies malignes humaines

article

Mutations of ETNK1 in aCML and CMML.

scientific article

Optical genome mapping refines cytogenetic diagnostics, prognostic stratification and provides new molecular insights in adult MDS/AML patients

scientific article published in 2022

Phosphatidylinositol 4-phosphatase type II is an erythropoietin-responsive gene.

scientific article

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

scientific article

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents.

scientific article published on 25 April 2018

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

scientific article

RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.

scientific article

Response to 5-azacytidine in a patient with TET2-mutated angioimmunoblastic T-cell lymphoma and chronic myelomonocytic leukaemia preceded by an EBV-positive large B-cell lymphoma.

scientific article published on 29 June 2016

SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias.

scientific article published on 5 February 2013

SF3B1 mutations in myelodysplastic syndromes: clinical associations and prognostic implications

scientific article published on 08 November 2011

Semaxinib (SU5416) as a therapeutic agent targeting oncogenic Kit mutants resistant to imatinib mesylate

scientific article published on 18 December 2006

Somatic mutations and epigenetic abnormalities in myelodysplastic syndromes.

scientific article published on December 2013

Spi-1/PU.1 participates in erythroleukemogenesis by inhibiting apoptosis in cooperation with Epo signaling and by blocking erythroid differentiation

scientific article published on 01 April 2007

Spliceosome mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia.

scientific article published in November 2012

Sustained leukemia-free state and molecular response to sorafenib in a patient with chronic myelomonocytic leukemia in transformation driven by homozygous FLT3-ITD malignant hematopoiesis.

scientific article

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

scientific article published on October 2009

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

scientific article

TET2 mutations in secondary acute myeloid leukemias: a French retrospective study ⬇️

scientific article published on April 20, 2011

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

scientific article published on 11 January 2019

Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket

scientific article

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