List of works - Mudra Hegde - Paulina

List of works by Mudra Hegde

Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2

scientific article published on 14 March 2022

Genetic screens in isogenic mammalian cell lines without single cell cloning

scientific article published on 06 February 2020

Optimization of AsCas12a for combinatorial genetic screens in human cells

scientific article published on 13 July 2020

Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities

scientific article published in Nature Communications

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

scientific article published on 18 January 2016

Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.

scientific article

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

scientific article

Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens.

scientific article published on 25 May 2018

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