Search filters

List of works by James S Wilmott

A light shines on melanoma metastagenesis

scientific article published on 19 June 2014

BAP1 expression in cutaneous melanoma: a pilot study

scientific article published in October 2013

BRAF mutation, NRAS mutation, and the absence of an immune-related expressed gene profile predict poor outcome in patients with stage III melanoma.

scientific article published on 30 August 2012

CD103+ Tumor-Resident CD8+ T Cells Are Associated with Improved Survival in Immunotherapy-Naïve Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment

scientific article published on 29 March 2018

Clinicopathologic features associated with efficacy and long-term survival in metastatic melanoma patients treated with BRAF or combined BRAF and MEK inhibitors

scientific article published on 28 July 2015

Close proximity of immune and tumor cells underlies response to anti-PD-1 based therapies in metastatic melanoma patients

scientific article published on 16 October 2019

Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study

scientific article published on 27 March 2018

Combined targeted therapy and immunotherapy in the treatment of advanced melanoma ⬇️

scientific article published on September 1, 2012

Comparison of whole-exome sequencing of matched fresh and formalin fixed paraffin embedded melanoma tumours: implications for clinical decision making

scientific article

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Concordant BRAFV600E mutation status in primary melanomas and associated naevi: implications for mutation testing of primary melanomas.

scientific article published in April 2014

Distinct Molecular Profiles and Immunotherapy Treatment Outcomes of V600E and V600K BRAF-Mutant Melanoma

scientific article published on 10 January 2019

Dynamic Changes in PD-L1 Expression and Immune Infiltrates Early During Treatment Predict Response to PD-1 Blockade in Melanoma.

scientific article published on 16 May 2017

Dynamics of chemokine, cytokine, and growth factor serum levels in BRAF-mutant melanoma patients during BRAF inhibitor treatment.

scientific article

Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment, and on progression.

scientific article published on 3 May 2013

How anti-PD1 treatments are changing the management of melanoma.

scientific article published in November 2014

Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma.

scientific article

Integrated molecular and immunophenotypic analysis of NK cells in anti-PD-1 treated metastatic melanoma patients

scientific article published on 31 October 2018

Intrapatient homogeneity of BRAFV600E expression in melanoma.

scientific article

Intratumoral molecular heterogeneity in a BRAF-mutant, BRAF inhibitor-resistant melanoma: a case illustrating the challenges for personalized medicine.

scientific article

Lymphatic vessel density in primary melanomas predicts sentinel lymph node status and risk of metastasis

scientific article published on 01 October 2012

Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade

scientific article published on 21 October 2019

Mutation load in melanoma is affected by MC1R genotype

scientific article published on 26 December 2016

Negative immune checkpoint regulation by VISTA: a mechanism of acquired resistance to anti-PD-1 therapy in metastatic melanoma patients.

scientific article published on 4 August 2017

Neoadjuvant dabrafenib combined with trametinib for resectable, stage IIIB-C, BRAFV600 mutation-positive melanoma (NeoCombi): a single-arm, open-label, single-centre, phase 2 trial

scientific article published on 03 June 2019

Novel Immune Targets in Melanoma-Response

scientific article published on 01 September 2019

PD-L1 Expression and Immune Escape in Melanoma Resistance to MAPK Inhibitors

scientific article

PD-L1 Expression and Tumor-Infiltrating Lymphocytes Define Different Subsets of MAPK Inhibitor-Treated Melanoma Patients.

scientific article

PD-L1 Negative Status is Associated with Lower Mutation Burden, Differential Expression of Immune-Related Genes, and Worse Survival in Stage III Melanoma

scientific article published on 9 March 2016

PD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trials

article

PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma

scientific article published on January 2013

Prevalence and Cellular Distribution of Novel Immune Checkpoint Targets Across Longitudinal Specimens in Treatment-naïve Melanoma Patients: Implications for Clinical Trials

scientific article published on 18 February 2019

Recurrent inactivating RASA2 mutations in melanoma

scientific article published on 26 October 2015

Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma

scientific article published on 12 December 2011

Sentinel lymph node biopsy in pediatric and adolescent cutaneous melanoma patients.

scientific article published on 12 August 2009

Synergistic effects of MAPK and immune checkpoint inhibitors in melanoma: what is the best combination strategy?

scientific article published on 25 February 2015

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition

scientific article published on 20 April 2020

Tumor CD155 expression is associated with resistance to anti-PD1 immunotherapy in metastatic melanoma

scientific article published on 28 April 2020

Tumor mutation burden and structural chromosomal aberrations are not associated with T-cell density or patient survival in acral, mucosal, and cutaneous melanomas

scientific article published on 11 September 2020

Tumour procurement, DNA extraction, coverage analysis and optimisation of mutation-detection algorithms for human melanoma genomes.

scientific article published on 29 October 2015

Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours

scientific article published on 15 May 2020

Whole genome sequencing of melanomas in adolescent and young adults reveals distinct mutation landscapes and the potential role of germline variants in disease susceptibility

scientific article published on 21 November 2018

Whole-genome landscapes of major melanoma subtypes.

scientific article published on 3 May 2017

bcGST-an interactive bias-correction method to identify over-represented gene-sets in boutique arrays

scientific article published on 01 April 2019

Paulina is supported by:

About Paulina

Help