List of works - Jacques Elion

Highly Variable Mutation Rates in Commensal and Pathogenic Escherichia coli

scientific article published in Science

Evolutionary implications of the frequent horizontal transfer of mismatch repair genes

scientific article

Phylogenetic analysis of Escherichia coli strains causing neonatal meningitis suggests horizontal gene transfer from a predominant pool of highly virulent B2 group strains

scientific article published on 01 March 1998

Commensal Escherichia coli isolates are phylogenetically distributed among geographically distinct human populations

scientific article published on 01 June 2001

Restriction pattern of the major outer-membrane protein gene provides evidence for a homogeneous invasive group among ruminant isolates of Chlamydia psittaci

scientific article published on November 1, 1991

Sex in Escherichia coli does not disrupt the clonal structure of the population: evidence from random amplified polymorphic DNA and restriction-fragment-length polymorphism

scientific article published on 01 October 1995

Molecular basis of methylmalonyl-CoA mutase apoenzyme defect in 40 European patients affected by mut(o) and mut- forms of methylmalonic acidemia: identification of 29 novel mutations in the MUT gene.

scientific article published in February 2005

Prothrombin

scientific article published on 01 January 1981

Analysis of DNA restriction fragment length polymorphism extends the evidence for breast milk transmission in Streptococcus agalactiae late-onset neonatal infection

scientific article published on March 1, 1992

Modulation of erythroid adhesion receptor expression by hydroxyurea in children with sickle cell disease

scientific article

Three-year follow-up of hydroxyurea treatment in severely ill children with sickle cell disease. The French Study Group on Sickle Cell Disease.

scientific article published on July 1997

Use of ribotyping in epidemiological surveillance of nosocomial outbreaks

scientific article published on July 1994

Mutation of SFTPC in infantile pulmonary alveolar proteinosis with or without fibrosing lung disease

scientific article published on 01 April 2004

Evidence for the genetic unrelatedness of nosocomial vancomycin-resistant Enterococcus faecium strains in a pediatric hospital.

scientific article published on September 1991

Molecular epidemiology of plasmid spread among extended broad-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates in a pediatric hospital.

scientific article published on February 1993

Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells.

scientific article published in January 2003

Left heart opacification with peripheral venous injection of a new saccharide echo contrast agent in dogs.

scientific article

Identification of a clone of Escherichia coli O103:H2 as a potential agent of hemolytic-uremic syndrome in France

scientific article

Cross-species characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene reveals multiple levels of regulation.

scientific article published on November 1997

Genotype–phenotype correlations in fetuses and neonates with autosomal recessive polycystic kidney disease

scientific article published on 25 November 2009

Usefulness of omp1 restriction mapping for avian Chlamydia psittaci isolate differentiation

scientific article published on February 1, 1995

DNA restriction fragment length polymorphism differentiates crossed from independent infections in nosocomial Xanthomonas maltophilia bacteremia

scientific article published on July 1, 1991

Rapid genotyping of the Chlamydia trachomatis major outer membrane protein by the polymerase chain reaction

scientific article published on September 15, 1991

Fetal hemoglobin and hydroxycarbamide moduate both plasma concentration and cellular origin of circulating microparticles in sickle cell anemia children

scientific article published on February 12, 2013

Neonatal screening for sickle cell disease in France.

scientific article

Mother-to-child transmitted WT1 splice-site mutation is responsible for distinct glomerular diseases

scientific article published on 01 October 1999

Virulence patterns of Escherichia coli K1 strains associated with neonatal meningitis.

scientific article published on November 1997

Chromosome 22q13.3 deletion syndrome with a de novo interstitial 22q13.3 cryptic deletion disrupting SHANK3.

scientific article

Analysis of the 677 C-->T mutation of the methylenetetrahydrofolate reductase gene in different ethnic groups

scientific article published on 01 January 1998

Strong association between a new marker of hemolysis and glomerulopathy in sickle cell anemia.

scientific article published on 15 September 2010

Prevalence of the G20210A polymorphism in the 3'-untranslated region of the prothrombin gene in different human populations.

scientific article published in January 1998

Correlation of continuous wave Doppler velocities with cardiac catheterization gradients: an experimental model of aortic stenosis

scientific article published on 01 December 1985

Molecular analysis provides evidence for the endogenous origin of bacteremia and meningitis due to Enterobacter cloacae in an infant.

scientific article published in July 1992

Infectious complications in sickle cell disease are influenced by HLA class II alleles.

scientific article

Preliminary report on the use of desferrioxamine in the treatment ofPlasmodium falciparum malaria

scientific article published on July 1, 1991

Sickle cell anemia in Guadeloupean children: pattern and prevalence of acute clinical events

scientific article published on 01 March 2006

Atypical ?s haplotypes are generated by diverse genetic mechanisms

scientific article published in February 2000

DNA restriction fragment length polymorphism differentiates recurrence from relapse in treatment failures of Streptococcus pyogenes pharyngitis

scientific article published on 01 September 1992

Differentiation of Escherichia coli strains using randomly amplified polymorphic DNA analysis.

scientific article published in February 1994

Systematic correlation of continuous-wave Doppler and hemodynamic measurements in patients with aortic stenosis.

scientific article published in February 1986

Mechanisms of the spread of penicillin resistance in Streptococcus pneumoniae strains causing meningitis in children in France

scientific article published on 01 September 1996

Genetic heterogeneity of Pseudomonas aeruginosa clinical isolates revealed by esterase electrophoretic polymorphism and restriction fragment length polymorphism of the ribosomal RNA gene region.

scientific article published in May 1994

Pathophysiological insights in sickle cell disease.

scientific article published on October 2011

Increased protein binding to a -530 mutation of the human beta-globin gene associated with decreased beta-globin synthesis

scientific article published on 01 January 1991

Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation

scientific article

Genetic polymorphism of the mannose-binding protein gene in children with sickle cell disease: identification of three new variant alleles and relationship to infections.

scientific article

Rapid genotyping shows the absence of cross-contamination in Enterobacter cloacae nosocomial infections.

scientific article published in June 1992

Heterogeneous ethnic distribution of the 844ins68 in the cystathionine beta-synthase gene

scientific article published on 01 November 1998

Loss of heterozygosity in the chromosomal region 12p12-13 is very common in childhood acute lymphoblastic leukemia and permits the precise localization of a tumor-suppressor gene distinct from p27KIP1.

scientific article published in November 1995

Association of UGT1A1 polymorphism with prevalence and age at onset of cholelithiasis in sickle cell anemia

scientific article published on 01 February 2005

List of works by Jacques Elion

Highly Variable Mutation Rates in Commensal and Pathogenic Escherichia coli

Evolutionary implications of the frequent horizontal transfer of mismatch repair genes

Phylogenetic analysis of Escherichia coli strains causing neonatal meningitis suggests horizontal gene transfer from a predominant pool of highly virulent B2 group strains

Commensal Escherichia coli isolates are phylogenetically distributed among geographically distinct human populations

Restriction pattern of the major outer-membrane protein gene provides evidence for a homogeneous invasive group among ruminant isolates of Chlamydia psittaci

Sex in Escherichia coli does not disrupt the clonal structure of the population: evidence from random amplified polymorphic DNA and restriction-fragment-length polymorphism

Molecular basis of methylmalonyl-CoA mutase apoenzyme defect in 40 European patients affected by mut(o) and mut- forms of methylmalonic acidemia: identification of 29 novel mutations in the MUT gene.

Prothrombin

Analysis of DNA restriction fragment length polymorphism extends the evidence for breast milk transmission in Streptococcus agalactiae late-onset neonatal infection

Modulation of erythroid adhesion receptor expression by hydroxyurea in children with sickle cell disease

Three-year follow-up of hydroxyurea treatment in severely ill children with sickle cell disease. The French Study Group on Sickle Cell Disease.

Use of ribotyping in epidemiological surveillance of nosocomial outbreaks

Mutation of SFTPC in infantile pulmonary alveolar proteinosis with or without fibrosing lung disease

Evidence for the genetic unrelatedness of nosocomial vancomycin-resistant Enterococcus faecium strains in a pediatric hospital.

Molecular epidemiology of plasmid spread among extended broad-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates in a pediatric hospital.

Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells.

Left heart opacification with peripheral venous injection of a new saccharide echo contrast agent in dogs.

Identification of a clone of Escherichia coli O103:H2 as a potential agent of hemolytic-uremic syndrome in France

Cross-species characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene reveals multiple levels of regulation.

Genotype–phenotype correlations in fetuses and neonates with autosomal recessive polycystic kidney disease

Usefulness of omp1 restriction mapping for avian Chlamydia psittaci isolate differentiation

DNA restriction fragment length polymorphism differentiates crossed from independent infections in nosocomial Xanthomonas maltophilia bacteremia

Rapid genotyping of the Chlamydia trachomatis major outer membrane protein by the polymerase chain reaction

Fetal hemoglobin and hydroxycarbamide moduate both plasma concentration and cellular origin of circulating microparticles in sickle cell anemia children

Neonatal screening for sickle cell disease in France.

Mother-to-child transmitted WT1 splice-site mutation is responsible for distinct glomerular diseases

Virulence patterns of Escherichia coli K1 strains associated with neonatal meningitis.

Chromosome 22q13.3 deletion syndrome with a de novo interstitial 22q13.3 cryptic deletion disrupting SHANK3.

Analysis of the 677 C-->T mutation of the methylenetetrahydrofolate reductase gene in different ethnic groups

Strong association between a new marker of hemolysis and glomerulopathy in sickle cell anemia.

Prevalence of the G20210A polymorphism in the 3'-untranslated region of the prothrombin gene in different human populations.

Correlation of continuous wave Doppler velocities with cardiac catheterization gradients: an experimental model of aortic stenosis

Molecular analysis provides evidence for the endogenous origin of bacteremia and meningitis due to Enterobacter cloacae in an infant.

Infectious complications in sickle cell disease are influenced by HLA class II alleles.

Preliminary report on the use of desferrioxamine in the treatment ofPlasmodium falciparum malaria

Sickle cell anemia in Guadeloupean children: pattern and prevalence of acute clinical events

Atypical ?s haplotypes are generated by diverse genetic mechanisms

DNA restriction fragment length polymorphism differentiates recurrence from relapse in treatment failures of Streptococcus pyogenes pharyngitis

Differentiation of Escherichia coli strains using randomly amplified polymorphic DNA analysis.

Systematic correlation of continuous-wave Doppler and hemodynamic measurements in patients with aortic stenosis.

Mechanisms of the spread of penicillin resistance in Streptococcus pneumoniae strains causing meningitis in children in France

Genetic heterogeneity of Pseudomonas aeruginosa clinical isolates revealed by esterase electrophoretic polymorphism and restriction fragment length polymorphism of the ribosomal RNA gene region.

Pathophysiological insights in sickle cell disease.

Increased protein binding to a -530 mutation of the human beta-globin gene associated with decreased beta-globin synthesis

Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation

Genetic polymorphism of the mannose-binding protein gene in children with sickle cell disease: identification of three new variant alleles and relationship to infections.

Rapid genotyping shows the absence of cross-contamination in Enterobacter cloacae nosocomial infections.

Heterogeneous ethnic distribution of the 844ins68 in the cystathionine beta-synthase gene

Loss of heterozygosity in the chromosomal region 12p12-13 is very common in childhood acute lymphoblastic leukemia and permits the precise localization of a tumor-suppressor gene distinct from p27KIP1.

Association of UGT1A1 polymorphism with prevalence and age at onset of cholelithiasis in sickle cell anemia