List of works - Luciano Ottonello

A novel role of the CX3CR1/CX3CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment.

scientific article

A review of the emerging profile of the anti-inflammatory drug oxaprozin

scientific article

Acipimox reduces circulating levels of insulin and associated neutrophilic inflammation in metabolic syndrome.

scientific article published on 25 January 2011

Activation of neutrophil respiratory burst by cytokines and chemoattractants. Regulatory role of extracellular matrix glycoproteins

scientific article published on 01 August 1998

Antiproliferative and proapoptotic activities of a new class of pyrazole derivatives in HL-60 cells.

scientific article published on October 2009

CCL19 and CXCL12 trigger in vitro chemotaxis of human mantle cell lymphoma B cells

scientific article (publication date: February 2004)

CCL3 (MIP-1α) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2

CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes

scientific article

Chemoattractant-induced release of elastase by tumor necrosis factor-primed human neutrophils: auto-regulation by endogenous adenosine

scientific article published on 01 December 1999

Chemokine receptor expression and function in childhood acute lymphoblastic leukemia of B-lineage

scientific article published on 22 August 2005

Chimaeric Lym-1 monoclonal antibody-mediated cytolysis by neutrophils from G-CSF-treated patients: stimulation by GM-CSF and role of Fc gamma -receptors.

scientific article published on August 2001

Coronary artery calcification and cardiovascular risk: the role of RANKL/OPG signalling

scientific article published on 23 May 2010

Delayed apoptosis of human monocytes exposed to immune complexes is reversed by oxaprozin: role of the Akt/IkappaB kinase/nuclear factor kappaB pathway

scientific article published on 26 March 2009

Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: possible relevance to the assays for the detection of micrometastatic breast cancer.

scientific article published in May 2005

Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation.

scientific article

FMLP- and TNF-stimulated monoclonal Lym-1 antibody-dependent lysis of B lymphoblastoid tumour targets by neutrophils.

scientific article published on May 1999

Human mesenchymal stem cells inhibit neutrophil apoptosis: a model for neutrophil preservation in the bone marrow niche

scientific article published on 11 October 2007

Immune complex stimulation of neutrophil apoptosis: investigating the involvement of oxidative and nonoxidative pathways

scientific article

Immune complexes induce monocyte survival through defined intracellular pathways.

scientific article published in January 2007

Induction of Neutrophil Chemotaxis by Leptin: Crucial Role for p38 and Src Kinases

scientific article published on 01 June 2006

Insulin Primes Human Neutrophils for CCL3-Induced Migration: Crucial Role for JNK 1/2

scientific article published on 01 December 2006

Intestinal radiation-induced stricture favours small bowel obstruction by phytobezoar: report of a case

scientific article published on 30 June 2009

Leptin as a uremic toxin interferes with neutrophil chemotaxis.

scientific article

Lymphoproliferative disorders and chemokines.

scientific article

Nephrotic syndrome in a patient with IgM myeloma with associated neutrophilia

Neutrophil dysfunction and increased susceptibility to infection

scientific article published on 01 September 1995

Neutrophil migration towards C5a and CXCL8 is prevented by non-steroidal anti-inflammatory drugs via inhibition of different pathways

scientific article

Nonleukoreduced red blood cell transfusion induces a sustained inhibition of neutrophil chemotaxis by stimulating in vivo production of transforming growth factor-beta1 by neutrophils: role of the immunoglobulinlike transcript 1, sFasL, and sHLA-I.

scientific article published in August 2007

Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways

scientific article published on 10 August 2009

Proteolytic inactivation of alpha-1-antitrypsin by human neutrophils: involvement of multiple and interlinked cell responses to phagocytosable targets

scientific article published on 01 January 1994

Stromal cell-derived factor-1 as a chemoattractant for follicular center lymphoma B cells

scientific article published on 01 April 2000

Sulphasalazine accelerates apoptosis in neutrophils exposed to immune complex: Role of caspase pathway.

scientific article published on 19 May 2009

Sulphonamides as anti-inflammatory agents: old drugs for new therapeutic strategies in neutrophilic inflammation?

scientific article published on 01 March 1995

Synthesis and Biological Evaluation ofN-Pyrazolyl-N‘-alkyl/benzyl/phenylureas: a New Class of Potent Inhibitors of Interleukin 8-Induced Neutrophil Chemotaxis

Synthesis and biological evaluation of neutrophilic inflammation inhibitors.

scientific article published in March 2004

Synthesis and biological evaluation of novel heterocyclic ionone-like derivatives as anti-inflammatory agents

scientific article published on 08 May 2006

Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke

scientific article

The anti-inflammatory drug nimesulide inhibits neutrophil adherence to and migration across monolayers of cytokine-activated endothelial cells

scientific article published on 01 January 1994

The chemokine network as therapeutic target in human diseases

scientific article published on 01 January 2006

The drug 5-aminosalicylic acid rescues alpha 1-proteinase inhibitor from the neutrophil oxidative inactivation. A possible contribution to its therapeutic action in ulcerative colitis

scientific article published on 01 January 1992

Transient inhibition of neutrophil migration following plasma or plasma-platelet apheresis donation procedures.

scientific article published on 25 November 2014

Triggering of respiratory burst by tumor necrosis factor in neutrophils adherent to fibronectin. Evidence for a crucial role of CD18 glycoproteins

scientific article published on 01 March 1994

Tumor cell lysis by activated human neutrophils: analysis of neutrophil-delivered oxidative attack and role of leukocyte function-associated antigen 1

scientific article published on 01 February 1991

Tumor necrosis factor (TNF) enhances the locomotion of low-density human tonsillar B lymphocytes through the selective triggering of type II receptor

scientific article published on 01 April 1997

Tumor necrosis factor-alpha (TNF-α) induces integrin CD11b/CD18 (Mac-1) up-regulation and migration to the CC chemokine CCL3 (MIP-1α) on human neutrophils through defined signalling pathways

article

Tumour necrosis factor alpha-induced oxidative burst in neutrophils adherent to fibronectin: effects of cyclic AMP-elevating agents

scientific article published on 01 November 1995

Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards

scientific article published on 12 April 2018

sHLA-I contaminating molecules as novel mechanism of ex vivo/in vitro transcriptional and posttranscriptional modulation of transforming growth factor-beta in CD8+ T lymphocytes and neutrophils after intravenous immunoglobulin treatment.

scientific article published on 9 November 2009

List of works by Luciano Ottonello

A novel role of the CX3CR1/CX3CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment.

A review of the emerging profile of the anti-inflammatory drug oxaprozin

Acipimox reduces circulating levels of insulin and associated neutrophilic inflammation in metabolic syndrome.

Activation of neutrophil respiratory burst by cytokines and chemoattractants. Regulatory role of extracellular matrix glycoproteins

Antiproliferative and proapoptotic activities of a new class of pyrazole derivatives in HL-60 cells.

CCL19 and CXCL12 trigger in vitro chemotaxis of human mantle cell lymphoma B cells

CCL3 (MIP-1α) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2

CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes

Chemoattractant-induced release of elastase by tumor necrosis factor-primed human neutrophils: auto-regulation by endogenous adenosine

Chemokine receptor expression and function in childhood acute lymphoblastic leukemia of B-lineage

Chimaeric Lym-1 monoclonal antibody-mediated cytolysis by neutrophils from G-CSF-treated patients: stimulation by GM-CSF and role of Fc gamma -receptors.

Coronary artery calcification and cardiovascular risk: the role of RANKL/OPG signalling

Delayed apoptosis of human monocytes exposed to immune complexes is reversed by oxaprozin: role of the Akt/IkappaB kinase/nuclear factor kappaB pathway

Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: possible relevance to the assays for the detection of micrometastatic breast cancer.

Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation.

FMLP- and TNF-stimulated monoclonal Lym-1 antibody-dependent lysis of B lymphoblastoid tumour targets by neutrophils.

Human mesenchymal stem cells inhibit neutrophil apoptosis: a model for neutrophil preservation in the bone marrow niche

Immune complex stimulation of neutrophil apoptosis: investigating the involvement of oxidative and nonoxidative pathways

Immune complexes induce monocyte survival through defined intracellular pathways.

Induction of Neutrophil Chemotaxis by Leptin: Crucial Role for p38 and Src Kinases

Insulin Primes Human Neutrophils for CCL3-Induced Migration: Crucial Role for JNK 1/2

Intestinal radiation-induced stricture favours small bowel obstruction by phytobezoar: report of a case

Leptin as a uremic toxin interferes with neutrophil chemotaxis.

Lymphoproliferative disorders and chemokines.

Nephrotic syndrome in a patient with IgM myeloma with associated neutrophilia

Neutrophil dysfunction and increased susceptibility to infection

Neutrophil migration towards C5a and CXCL8 is prevented by non-steroidal anti-inflammatory drugs via inhibition of different pathways

Nonleukoreduced red blood cell transfusion induces a sustained inhibition of neutrophil chemotaxis by stimulating in vivo production of transforming growth factor-beta1 by neutrophils: role of the immunoglobulinlike transcript 1, sFasL, and sHLA-I.

Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways

Proteolytic inactivation of alpha-1-antitrypsin by human neutrophils: involvement of multiple and interlinked cell responses to phagocytosable targets

Stromal cell-derived factor-1 as a chemoattractant for follicular center lymphoma B cells

Sulphasalazine accelerates apoptosis in neutrophils exposed to immune complex: Role of caspase pathway.

Sulphonamides as anti-inflammatory agents: old drugs for new therapeutic strategies in neutrophilic inflammation?

Synthesis and Biological Evaluation ofN-Pyrazolyl-N‘-alkyl/benzyl/phenylureas: a New Class of Potent Inhibitors of Interleukin 8-Induced Neutrophil Chemotaxis

Synthesis and biological evaluation of neutrophilic inflammation inhibitors.

Synthesis and biological evaluation of novel heterocyclic ionone-like derivatives as anti-inflammatory agents

Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke

The anti-inflammatory drug nimesulide inhibits neutrophil adherence to and migration across monolayers of cytokine-activated endothelial cells

The chemokine network as therapeutic target in human diseases

The drug 5-aminosalicylic acid rescues alpha 1-proteinase inhibitor from the neutrophil oxidative inactivation. A possible contribution to its therapeutic action in ulcerative colitis

Transient inhibition of neutrophil migration following plasma or plasma-platelet apheresis donation procedures.

Triggering of respiratory burst by tumor necrosis factor in neutrophils adherent to fibronectin. Evidence for a crucial role of CD18 glycoproteins

Tumor cell lysis by activated human neutrophils: analysis of neutrophil-delivered oxidative attack and role of leukocyte function-associated antigen 1

Tumor necrosis factor (TNF) enhances the locomotion of low-density human tonsillar B lymphocytes through the selective triggering of type II receptor

Tumor necrosis factor-alpha (TNF-α) induces integrin CD11b/CD18 (Mac-1) up-regulation and migration to the CC chemokine CCL3 (MIP-1α) on human neutrophils through defined signalling pathways

Tumour necrosis factor alpha-induced oxidative burst in neutrophils adherent to fibronectin: effects of cyclic AMP-elevating agents

Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards

sHLA-I contaminating molecules as novel mechanism of ex vivo/in vitro transcriptional and posttranscriptional modulation of transforming growth factor-beta in CD8+ T lymphocytes and neutrophils after intravenous immunoglobulin treatment.