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List of works by Manal F Abdelmalek

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of GS-9450 in Subjects With Nonalcoholic Steatohepatitis ⬇️

scientific article published on December 14, 2011

A Randomized, Placebo-Controlled Trial of Cenicriviroc for Treatment of Nonalcoholic Steatohepatitis with Fibrosis.

scientific article published on 17 August 2017

A longer duration of estrogen deficiency increases fibrosis risk among postmenopausal women with nonalcoholic fatty liver disease

scientific article published on 26 February 2016

Analyzing the Impact of Increasing Mechanical Index and Energy Deposition on Shear Wave Speed Reconstruction in Human Liver

scientific article

Association Between Magnetic Resonance Imaging-Proton Density Fat Fraction and Liver Histology Features in Patients With Nonalcoholic Fatty Liver Disease or Nonalcoholic Steatohepatitis

scientific article published on 19 July 2018

Association Between Puberty and Features of Nonalcoholic Fatty Liver Disease ⬇️

scientific article published on February 14, 2012

Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study

scientific article published in PLoS ONE

Case definitions for inclusion and analysis of endpoints in clinical trials for nonalcoholic steatohepatitis through the lens of regulatory science.

scientific article published on 23 October 2017

Cenicriviroc for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis: AURORA Phase 3 study design

scientific article published on 24 December 2019

Current and Future Therapeutic Regimens for Non-alcoholic Fatty Liver Disease (NAFLD) and Non-alcoholic Steatohepatitis (NASH).

scientific article

De Novo and Recurrence of Nonalcoholic Steatohepatitis After Liver Transplantation

scientific article

Derivation and analysis of viscoelastic properties in human liver: impact of frequency on fibrosis and steatosis staging.

scientific article

Diagnostic Modalities for Non-alcoholic Fatty Liver Disease (NAFLD), Non-alcoholic Steatohepatitis (NASH) and Associated Fibrosis.

scientific article published on 9 December 2017

Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

scientific article

Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury

scientific article published on 01 December 2019

Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis

scientific article published on 15 September 2018

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.

scientific article published on 31 January 2018

Gender and menopause impact severity of fibrosis among patients with nonalcoholic steatohepatitis.

scientific article published on 18 February 2014

Genetic signatures in choline and 1‐carbon metabolism are associated with the severity of hepatic steatosis ⬇️

scientific article published on January 4, 2013

Hedgehog pathway and pediatric nonalcoholic fatty liver disease ⬇️

scientific article published on April 1, 2013

Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.

scientific article published on 13 December 2013

Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes ⬇️

scientific article published on July 12, 2012

Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels

scientific article published on 01 October 2019

IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients.

scientific article published on 11 October 2012

Increased production of sonic hedgehog by ballooned hepatocytes ⬇️

scientific article published on May 5, 2011

Liver Transplantation for Nonalcoholic Steatohepatitis: Pathophysiology of Recurrence and Clinical Challenges

scientific article published on 16 July 2019

Longitudinal Correlations Between MRE, MRI-PDFF, and Liver Histology in Patients with Nonalcoholic Steatohepatitis: Analysis of Data from a Phase 2 Trial of Selonsertib

article

NAFLD: The clinical and economic burden of NAFLD: time to turn the tide.

scientific article published on 9 November 2016

NGM282 for treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

scientific article published on 5 March 2018

NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease ⬇️

scientific article published on March 17, 2012

Nonalcoholic Fatty Liver Disease

scientific article published on 01 May 2016

Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis

scientific article published on 16 July 2018

PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease

scientific article published on 28 August 2019

Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial

scientific article published on 13 December 2018

Performance characteristics of vibration-controlled transient elastography for evaluation of nonalcoholic fatty liver disease

scientific article published on 31 August 2017

Posttransplant Outcome of Lean Compared With Obese Nonalcoholic Steatohepatitis in the United States: The Obesity Paradox

scientific article published on 01 January 2020

Randomized placebo-controlled trial of emricasan for non-alcoholic steatohepatitis-related cirrhosis with severe portal hypertension

scientific article published on 21 December 2019

Rectal Bleeding from a Mucous Fistula Secondary to a Dieulafoy's Lesion ⬇️

scientific article published on 01 June 1997

Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease

scientific article published on 31 July 2013

Relationship between three commonly used non-invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non-alcoholic steatohepatitis

scientific article published on 21 February 2019

Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism.

scientific article

Reply

Reply to Kim et al.

scientific article published in May 2017

Rosuvastatin improves the FGF19 analogue NGM282-associated lipid changes in patients with non-alcoholic steatohepatitis

scientific article published on 08 December 2018

Sex Differences in Nonalcoholic Fatty Liver Disease: State of the Art and Identification of Research Gaps

scientific article published on 23 September 2019

Simtuzumab Is Ineffective for Patients with Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis

article

Sirolimus Conversion Regimen Versus Continued Calcineurin Inhibitors in Liver Allograft Recipients: A Randomized Trial ⬇️

scientific article published on January 10, 2012

Systematic transcriptome analysis reveals elevated expression of alcohol-metabolizing genes in NAFLD livers

scientific article published on 28 September 2015

The Conundrum of Cryptogenic Cirrhosis: Adverse Outcomes without Treatment Options

scientific article published on 23 August 2018

The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials

scientific article published on 28 May 2019

Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity

scientific article

Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis

scientific article published on 15 November 2018

Vibration-Controlled Transient Elastography to Assess Fibrosis and Steatosis in Patients With Nonalcoholic Fatty Liver Disease

scientific article published on 26 April 2018

Vitamin D is Not Associated With Severity in NAFLD: Results of a Paired Clinical and Gene Expression Profile Analysis.

scientific article published on 20 September 2016

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