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List of works by Clyde W Hodge

A role for corticotropin releasing factor (CRF) in ethanol consumption, sensitivity, and reward as revealed by CRF-deficient mice.

scientific article published on 24 October 2002

Activation of group II metabotropic glutamate receptors inhibits the discriminative stimulus effects of alcohol via selective activity within the amygdala.

scientific article

Adolescent C57BL/6J mice show elevated alcohol intake, but reduced taste aversion, as compared to adult mice: a potential behavioral mechanism for binge drinking.

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Alcohol alters the activation of ERK1/2, a functional regulator of binge alcohol drinking in adult C57BL/6J mice

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Alcohol self-administration: further examination of the role of dopamine receptors in the nucleus accumbens.

scientific article published in September 1997

Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice.

scientific article published on 23 October 2009

CaMKII inhibition in the prefrontal cortex specifically increases the positive reinforcing effects of sweetened alcohol in C57BL/6J mice

scientific article published on 19 November 2015

CaMKIIα-GluA1 Activity Underlies Vulnerability to Adolescent Binge Alcohol Drinking

scientific article

Cannabinoid CB1 receptor inhibition blunts adolescent-typical increased binge alcohol and sucrose consumption in male C57BL/6J mice

scientific article published on 19 January 2016

Comparison of ethanol locomotor sensitization in adolescent and adult DBA/2J mice.

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Comparison of the adolescent and adult mouse prefrontal cortex proteome

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Comparison of the discriminative stimulus function of ethanol following intracranial and systemic administration: evidence of a central mechanism.

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Coregulation of ethanol discrimination by the nucleus accumbens and amygdala.

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Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP

scientific article published on 04 July 2008

Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.

scientific article

Delayed developmental changes in neonatal vocalizations correlates with variations in ventral medial hypothalamus and central amygdala development in the rodent infant: Effects of prenatal cocaine

scientific article published on August 4, 2012

Deletion of the 5-HT(3A)-receptor subunit blunts the induction of cocaine sensitization.

scientific article published on 7 June 2007

Effect of dopamine agonists and antagonists on ethanol-reinforced behavior: the involvement of the nucleus accumbens.

scientific article published in January 1993

Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release.

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Effects of intraaccumbens injections of dopamine agonists and antagonists on sucrose and sucrose-ethanol reinforced responding.

scientific article published in May 1994

Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats.

scientific article published on February 2008

Effects of ventral tegmental microinjections of the GABAA agonist muscimol on self-administration of ethanol and sucrose.

scientific article published in April 1996

Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake.

scientific article published in May 2002

Enhanced AMPA receptor activity increases operant alcohol self-administration and cue-induced reinstatement

scientific article published on 6 November 2012

Ethanol preexposure increases ethanol self-administration in C57BL/6J and DBA/2J mice.

scientific article published in December 2004

Ethanol-induced alterations of c-Fos immunoreactivity in specific limbic brain regions following ethanol discrimination training.

scientific article published on 26 July 2008

Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression.

scientific article published in December 2000

GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.

scientific article published in September 2002

GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice.

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GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon

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GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats.

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Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.

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Increased response to morphine in mice lacking protein kinase C epsilon

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Increased sensitivity to alcohol induced changes in ERK Map kinase phosphorylation and memory disruption in adolescent as compared to adult C57BL/6J mice.

scientific article published on 13 February 2012

Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens

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Intra-amygdala inhibition of ERK(1/2) potentiates the discriminative stimulus effects of alcohol.

scientific article published on 23 December 2011

MGluR5 activity is required for the induction of ethanol behavioral sensitization and associated changes in ERK MAP kinase phosphorylation in the nucleus accumbens shell and lateral habenula

scientific article published on 23 March 2019

Maternal oral intake mouse model for fetal alcohol spectrum disorders: ocular defects as a measure of effect.

scientific article published in October 2006

Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake

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Microdialysis in the mouse nucleus accumbens: a method for detection of monoamine and amino acid neurotransmitters with simultaneous assessment of locomotor activity.

scientific article published on February 2000

Microinjections of dopamine agonists in the nucleus accumbens increase ethanol-reinforced responding

scientific article published on September 1, 1992

Mining the nucleus accumbens proteome for novel targets of alcohol self-administration in male C57BL/6J mice

scientific article published on 3 March 2018

Moderate Alcohol Drinking and the Amygdala Proteome: Identification and Validation of Calcium/Calmodulin Dependent Kinase II and AMPA Receptor Activity as Novel Molecular Mechanisms of the Positive Reinforcing Effects of Alcohol

scientific article published on 31 October 2014

Modulation of extracellular neurotransmitter levels in the nucleus accumbens by a taurine uptake inhibitor

scientific article published on 01 December 2000

Morphine induced changes in ethanol-and water-intake are attenuated by the 5-HT3/4 antagonist tropisetron (ICS 205-930)

scientific article published on 01 May 1995

Neuropeptide-Y in the paraventricular nucleus increases ethanol self-administration

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Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082.

scientific article published on 14 June 2008

Norepinephrine and serotonin receptors in the paraventricular nucleus interactively modulate ethanol consumption

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Operant ethanol self-administration increases extracellular-signal regulated protein kinase (ERK) phosphorylation in reward-related brain regions: selective regulation of positive reinforcement in the prefrontal cortex of C57BL/6J mice.

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Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration.

scientific article published on April 2014

Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.

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Potentiation of amygdala AMPA receptor activity selectively promotes escalated alcohol self-administration in a CaMKII-dependent manner

scientific article published on 6 January 2016

Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms

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Pregnenolone and Ganaxolone Reduce Operant Ethanol Self‐Administration in Alcohol‐Preferring P Rats

scientific article published on October 14, 2010

Reduced 5-HT3 receptor binding and lower baseline plus maze anxiety in the alcohol-preferring inbred fawn-hooded rat.

scientific article published in February 2004

Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats.

scientific article published on 21 December 2007

Specific and nonspecific effects of naltrexone on goal-directed and habitual models of alcohol seeking and drinking.

scientific article published on 7 February 2013

Targeted gene deletion of the 5-HT3A receptor subunit produces an anxiolytic phenotype in mice.

scientific article

The 5-HT3 antagonist Y-25130 blocks cocaine-induced lowering of ICSS reward thresholds in the rat.

scientific article published in January 2003

The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions.

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The discriminative stimulus properties of self-administered ethanol are mediated by GABA(A) and NMDA receptors in rats.

scientific article published in February 2001

The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance

scientific article published on September 1, 1997

The effects of repeated corticosterone exposure on the interoceptive effects of alcohol in rats

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The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats.

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The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice.

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Ventral tegmental microinjections of quinpirole decrease ethanol and sucrose-reinforced responding.

scientific article published in April 1993

mGlu5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in rats

scientific article