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List of works by David J Clarke

An affinity purification procedure to isolate oxidized p53

scientific article published on 01 September 2011

Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3.

scientific article published on 7 January 2008

Autopiquer - a Robust and Reliable Peak Detection Algorithm for Mass Spectrometry

scientific article published on 6 December 2016

Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements

scientific article published on 06 March 2010

Biotinylation in the hyperthermophile Aquifex aeolicus

scientific article published in March 2003

Cellular redox potential and the biomolecular electrochemical series: a systems hypothesis

scientific article published on 17 May 2012

Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei

scientific article

Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei

scientific article

Chemical Diversity and Complexity of Scotch Whisky as Revealed by High-Resolution Mass Spectrometry

scientific article (publication date: 2017)

Cloning, expression, purification, crystallization and preliminary X-ray characterization of the full-length single-stranded DNA-binding protein from the hyperthermophilic bacterium Aquifex aeolicus.

scientific article

Complementary Ionization Techniques for the Analysis of Scotch Whisky by High Resolution Mass Spectrometry

scientific article published on 18 September 2018

Conformational preferences of linear beta-defensins are revealed by ion mobility-mass spectrometry

scientific article

Conservation of the structural and functional architecture of encapsulated ferritins in bacteria and archaea

scientific article published on 22 March 2019

Covalent dimer species of beta-defensin Defr1 display potent antimicrobial activity against multidrug-resistant bacterial pathogens

scientific article published on 12 March 2007

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6.

scientific article

Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution.

scientific article

Determination of Protein Thiol Reduction Potential by Isotope Labeling and Intact Mass Measurement

scientific article

Dissecting the dynamic conformations of the metamorphic protein lymphotactin

scientific article published on 20 October 2014

Dissection of the DNA mimicry of the bacteriophage T7 Ocr protein using chemical modification

scientific article

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

scientific article

Efficient production of human beta-defensin 2 (HBD2) in Escherichia coli

scientific article

Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex

scientific article

IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2.

scientific article published on 09 September 2016

Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry

scientific article

Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation

scientific article

Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans

scientific article published on 22 February 2016

Insights into the conformations of three structurally diverse proteins: cytochrome c, p53, and MDM2, provided by variable-temperature ion mobility mass spectrometry

scientific article published on 25 February 2015

Interactive van Krevelen diagrams - Advanced visualisation of mass spectrometry data of complex mixtures

scientific article published on 7 January 2017

Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry

scientific article published on 19 August 2020

Interrogating the molecular details of the peroxiredoxin activity of the Escherichia coli bacterioferritin comigratory protein using high-resolution mass spectrometry

scientific article published in May 2009

Isotope Depletion Mass Spectrometry (ID-MS) for Accurate Mass Determination and Improved Top-Down Sequence Coverage of Intact Proteins

scientific article published on 11 February 2020

Isotope Depletion Mass Spectrometry (ID-MS) for Enhanced Top-Down Protein Fragmentation

MALDI Matrix Application Utilizing a Modified 3D Printer for Accessible High Resolution Mass Spectrometry Imaging

scientific article published on 27 July 2018

Mapping a noncovalent protein-peptide interface by top-down FTICR mass spectrometry using electron capture dissociation

scientific article published on 11 May 2011

Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond

scientific article

Mass spectrometry reveals the assembly pathway of encapsulated ferritins and highlights a dynamic ferroxidase interface

scientific article published on 24 February 2020

Maturation of McjA precursor peptide into active microcin MccJ25.

scientific article published in August 2007

Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone

scientific article

Native ion mobility mass spectrometry reveals that small organic acid fragments impart gas-phase stability to carbonic anhydrase II

scientific article published on 01 January 2020

New cytotoxic callipeltins from the Solomon Island marine sponge Asteropus sp

Online quench-flow electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for elucidating kinetic and chemical enzymatic reaction mechanisms

scientific article published in March 2010

Plant host and sugar alcohol induced exopolysaccharide biosynthesis in the Burkholderia cepacia complex

scientific article published in August 2008

Preparation of isotopically labelled recombinant beta-defensin for NMR studies

scientific article

Probing the Conformational Diversity of Cancer-Associated Mutations in p53 with Ion-Mobility Mass Spectrometry

scientific article published on 14 March 2013

Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis

scientific article published in August 2013

Restriction endonuclease TseI cleaves A:A and T:T mismatches in CAG and CTG repeats

scientific article published on 23 March 2013

S-nitrosylation of the zinc finger protein SRG1 regulates plant immunity

scientific article published in Nature Communications

Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity

scientific article

Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments

scientific article published on 16 August 2016

Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments

Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity

scientific article

Subdivision of the bacterioferritin comigratory protein family of bacterial peroxiredoxins based on catalytic activity

scientific article

The chemical basis of serine palmitoyltransferase inhibition by myriocin

scientific article

The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein

scientific article

Untargeted Metabolite Mapping in 3D Cell Culture Models Using High Spectral Resolution FT-ICR Mass Spectrometry Imaging

scientific article published on 16 July 2019

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