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List of works by Dorota Łażewska

(2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H4 receptor ligands

scientific article published on 10 August 2015

4-tert-Pentylphenoxyalkyl derivatives - Histamine H receptor ligands and monoamine oxidase B inhibitors

scientific article published on 31 October 2018

Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands

scientific article published on 12 February 2019

Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats

scientific article published on 30 March 2020

Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats.

scientific article published on 22 October 2015

Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats

scientific article published on 03 May 2018

Antinociceptive effects of novel histamine H3 R and H4 R receptor antagonists and their influence on morphine analgesia of neuropathic pain in the mouse.

scientific article published on 27 February 2018

Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro

scientific article published on 06 December 2019

Aryl-1,3,5-triazine derivatives as histamine H4 receptor ligands.

scientific article

Aryl-1,3,5-triazine ligands of histamine H4 receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide

scientific article published on 20 October 2016

Azines as histamine H4 receptor antagonists ⬇️

scientific article published on January 1, 2012

Biphenylalkoxyamine Derivatives-Histamine H Receptor Ligands with Butyrylcholinesterase Inhibitory Activity

scientific article published on 11 June 2021

Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H3 receptor ligands

scientific article published on 29 July 2017

Chlorophenoxy aminoalkyl derivatives as histamine H(3)R ligands and antiseizure agents.

scientific article published on 2 December 2015

Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands.

scientific article published on 20 April 2016

Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT₆ Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo

scientific article published on 03 October 2018

Convenient way of synthesis and crystal structure of 1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine, a histamine H4 receptor antagonist

Corrigendum to "Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands" [Eur. J. Med. Chem. 185 (2020) 111785]

scientific article published on 10 August 2020

Cunninghamella as a microbiological model for metabolism of histamine H(3) receptor antagonist 1-[3-(4-tert-butylphenoxy)propyl]piperidine.

scientific article published on 16 September 2012

Determination of in vitro metabolism of new non-imidazole histamine H3 receptor antagonist 1-[3-(4-tert-butylphenoxy)propyl]piperidine

scientific article published on 30 October 2019

Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H3 Receptor Antagonists and Monoamine Oxidase B Inhibitors ⬇️

scientific article published on 12 May 2020

Eosinophils adhesion assay as a tool for phenotypic drug screening - The pharmacology of 1,3,5 - Triazine and 1h-indole like derivatives against the human histamine H4 receptor

scientific article published on 02 October 2020

Filozofia dla pracujących ⬇️

book published in 2011

Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats

scientific article published on 20 February 2019

Histamine H3R Antagonists: From Scaffold Hopping to Clinical Candidates

scientific article published in 2016

In silico and in vitro studies on interaction of novel non-imidazole histamine H3R antagonists with CYP3A4

scientific article published on 29 March 2020

LC-MS-MS Method for the Analysis of New Non-Imidazole Histamine H(3) Receptor Antagonist 1-[3-(4-tert-Butylphenoxy)propyl]piperidine in Rat Serum-Application to Pharmacokinetic Studies

scientific article published on 25 February 2011

New developments around histamine H3receptor antagonists/inverse agonists: a patent review (2010 – present) ⬇️

scientific article published on October 17, 2013

Novel naphthyloxy derivatives - Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation.

scientific article published on 11 April 2018

Pharmacokinetics and tissue distribution of the new non-imidazole histamine H3 receptor antagonist 1-[3-(4-tert-butylphenoxy) propyl]piperidine in rats.

scientific article

Progress in the development of histamine H3 receptor antagonists/inverse agonists: a patent review (2013-2017).

scientific article published on 15 January 2018

Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease

scientific article published on 21 August 2020

Role of Histamine H₃ Receptor Antagonists on Intraocular Pressure Reduction in Rabbit Models of Transient Ocular Hypertension and Glaucoma

scientific article published on 24 February 2019

Search for histamine H4 receptor ligands in the group of 4-methylpiperazino amide derivatives.

scientific article

Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands

scientific article published on 17 October 2019

Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism

scientific article published on 28 August 2020

Structure-activity relationships of imidazothiazinones and analogs as antagonists of the cannabinoid-activated orphan G protein-coupled receptor GPR18

scientific article published on 01 June 2018

Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats

scientific article published on 29 October 2018

Synthesis and biological activity of novel tert-amylphenoxyalkyl (homo)piperidine derivatives as histamine H3R ligands.

scientific article

Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT6

scientific article published on 10 June 2019

Synthesis and computer-aided analysis of the role of linker for novel ligands of the 5-HT6 serotonin receptor among substituted 1,3,5-triazinylpiperazines

scientific article published on 26 November 2018

The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice

scientific article published on 03 June 2020

The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats

scientific article published on 12 October 2017

The Neuroprotective Effects of Histamine H3 Receptor Antagonist E177 on Pilocarpine-Induced Status Epilepticus in Rats

scientific article published on 14 November 2019

The Search for Histamine H 4 Receptor Ligands with Anticancer Activity among Novel (Thio)urea Derivatives

scientific article published on 29 September 2019

The Synthesis of 1,3,5-triazine Derivatives and JNJ7777120 Analogues with Histamine H4 Receptor Affinity and Their Interaction with PTEN Promoter

The computer-aided discovery of novel family of the 5-HT6 serotonin receptor ligands among derivatives of 4-benzyl-1,3,5-triazine

scientific article published on 13 April 2017

The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammmation in sodium valproate induced autism in mice

scientific article published on 30 July 2019

The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism.

scientific article published on 30 August 2018

The lipophilicity estimation of 5-arylidene derivatives of (2-thio)hydantoin with antimycobacterial activity

scientific article published in March 2007

The novel non-imidazole histamine H3 receptor antagonist DL77 reduces voluntary alcohol intake and ethanol-induced conditioned place preference in mice

scientific article published on 10 July 2015

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