List of works - Man-Fung Yuen

A large case-control study on the predictability of hepatitis B surface antigen levels three years before hepatitis B surface antigen seroclearance.

scientific article published on 10 July 2012

A large real-world cohort study examining the effects of long-term entecavir on hepatocellular carcinoma and HBsAg seroclearance

scientific article published on 09 December 2019

A new model using routinely available clinical parameters to predict significant liver fibrosis in chronic hepatitis B

scientific article (publication date: 2011)

An update on the toxicological considerations for protease inhibitors used for hepatitis C infection.

scientific article

Application of coamplification at lower denaturation temperature-PCR sequencing for early detection of antiviral drug resistance mutations of hepatitis B virus.

scientific article published on 20 June 2014

Artificial neural network accurately predicts hepatitis B surface antigen seroclearance.

scientific article

Association Between Hepatic Steatosis, Measured by Controlled Attenuation Parameter, and Fibrosis Burden in Chronic Hepatitis B.

scientific article published on 29 September 2017

Association of Hepatitis B Core-Related Antigen With Hepatitis B Virus Reactivation in Occult Viral Carriers Undergoing High-Risk Immunosuppressive Therapy.

scientific article published on 20 September 2016

Association of adipokines with hepatic steatosis and fibrosis in chronic hepatitis B patients on long-term nucleoside analogue

scientific article published on 11 April 2019

Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in chronic hepatitis B.

scientific article

Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after 5 years of entecavir treatment

scientific article published on May 2014

Chronic Hepatitis B Virus Infection: Disease Revisit and Management Recommendations

scientific article published on 2 February 2016

Clinical outcome and virologic profiles of severe hepatitis B exacerbation due to YMDD mutations.

scientific article published in November 2003

Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma.

scientific article published on 4 August 2011

Combination of baseline parameters and on-treatment hepatitis B virus DNA levels to start and continue patients with lamivudine therapy.

scientific article published in January 2009

Correlation of liver stiffness and histological features in healthy persons and in patients with occult hepatitis B, chronic active hepatitis B, or hepatitis B cirrhosis.

scientific article published on 17 November 2009

Correlation of serum Mac-2-binding protein glycosylation isomer (M2BPGi) and liver stiffness in chronic hepatitis B infection

scientific article published on 22 January 2019

Corrigendum to “Profiles of HBV DNA in a large population of Chinese patients with chronic hepatitis B: Implications for antiviral therapy” [J Hepatol 2011;54:195–200]

article

Current Antiviral Therapy of Chronic Hepatitis B: Efficacy and Safety

scientific article published on 9 August 2011

DNA polymerase inhibitors for treating hepatitis B: a safety evaluation.

scientific article

Deep sequencing analysis of quasispecies in the HBV pre-S region and its association with hepatocellular carcinoma.

scientific article published on 28 March 2017

Defining normal liver stiffness range in a normal healthy Chinese population without liver disease

scientific article published on 26 December 2013

Development of predisposition, injury, response, organ failure model for predicting acute kidney injury in acute on chronic liver failure.

scientific article

East Asia expert opinion on treatment initiation for chronic hepatitis B

scientific article published on 20 September 2020

Emerging drugs for the treatment of hepatitis B.

scientific article published on 3 March 2016

Entecavir Reduced Serum Hepatitis B Core-Related Antigen in Chronic Hepatitis B Patients with Hepatocellular Carcinoma

scientific article published on 29 May 2020

Epidemiology and natural history of Wilson's disease in the Chinese: A territory-based study in Hong Kong between 2000 and 2016.

scientific article published in November 2017

Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region

scientific article

Estradiol induces apoptosis via activation of miRNA-23a and p53: implication for gender difference in liver cancer development.

scientific article published on 30 September 2015

Evidence of serologic activity in chronic hepatitis B after surface antigen (HBsAg) seroclearance documented by conventional HBsAg assay

scientific article published on 13 March 2012

Evolutionary Changes of Hepatitis B Virus Pre-S Mutations Prior to Development of Hepatocellular Carcinoma

scientific article published on 30 September 2015

Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment.

scientific article published on March 2014

Fibrosis evolution in chronic hepatitis B e antigen-negative patients across a 10-year interval

scientific article published on 16 April 2019

Future prevention and treatment of chronic hepatitis B infection.

scientific article published on October 2012

Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection.

scientific article

HBV RNA profiles in chronic hepatitis B patients under different disease phases and anti-viral therapy

scientific article published on 06 November 2020

HBsAg seroclearance in chronic hepatitis B in the Chinese: virological, histological, and clinical aspects.

scientific article

Hepatitis B Surface Antigen Seroclearance: Relationship to Hepatitis B e-Antigen Seroclearance and Hepatitis B e-Antigen-Negative Hepatitis

scientific article published on 23 September 2014

Hepatitis B core protein as a therapeutic target.

scientific article

Hepatitis B core-related antigen levels after HBeAg seroconversion is associated with the development of hepatocellular carcinoma

scientific article published on 02 September 2019

Hepatitis B reactivation in occult viral carriers undergoing hematopoietic stem cell transplantation: A prospective study.

scientific article published on 27 December 2016

Hepatitis B reactivation in patients with previous hepatitis B virus exposure undergoing rituximab-containing chemotherapy for lymphoma: a prospective study.

scientific article published on 6 October 2014

Hepatitis B surface antigen levels after hepatitis B e-antigen seroclearance: a longitudinal follow-up study

scientific article published on 4 June 2014

Hepatitis B surface antigen seroclearance during nucleoside analogue therapy: surface antigen kinetics, outcomes, and durability.

scientific article

Hepatitis B virus core-related antigen as a surrogate marker for covalently closed circular DNA.

scientific article published on 19 December 2016

Hepatitis B virus full-length genomic mutations and quasispecies in hepatocellular carcinoma

scientific article

Hepatitis B: treatment choice and monitoring for response and resistance.

scientific article

High hepatitis B surface antigen levels predict insignificant fibrosis in hepatitis B e antigen positive chronic hepatitis B.

scientific article

Interleukin-1β increases the risk of gastric cancer through induction of aberrant DNA methylation in a mouse model

scientific article published on March 2016

Inverse relationship between hepatic steatosis and hepatitis B viremia: Results of a large case-control study.

scientific article published on 3 August 2017

Ketamine-induced cholangiopathy: a case report.

scientific article published on May 2011

Letter: serum HBcrAg is a useful marker for disease monitoring, predicting treatment response and disease outcome of chronic hepatitis B virus infection-authors' reply

scientific article published on 01 June 2018

Long Term Outcomes and Predictive Scores for Hepatocellular Carcinoma and HBsAg Seroclearance after HBeAg Seroclearance.

scientific article

Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease.

scientific article published in January 2007

Long-term outcomes of entecavir monotherapy for chronic hepatitis B after liver transplantation: Results up to 8 years.

scientific article published on 31 March 2017

Longitudinal profiles of highly sensitive hepatitis B surface antigen levels: re-evaluation of HBsAg seroclearance.

scientific article

Longitudinal study of hepatitis activity and viral replication before and after HBeAg seroconversion in chronic hepatitis B patients infected with genotypes B and C.

scientific article

Model for End-stage Liver Disease with additional criteria to predict short-term mortality in severe flares of chronic hepatitis B

scientific article published on 23 December 2019

Mutational analysis for Wilson's disease.

scientific article

New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia

scientific article

No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.

scientific article

Nucleoside/nucleotide analogues in the treatment of chronic hepatitis B

scientific article

Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma.

scientific article

Oral nucleos(t)ide Analogs Alone After Liver Transplantation in Chronic Hepatitis B with Preexisting rt204 Mutation

scientific article published on 21 July 2017

Oral nucleoside/nucleotide analogs without hepatitis B immune globulin after liver transplantation for hepatitis B.

scientific article published on 30 April 2013

Outcomes including liver histology after liver transplantation for chronic hepatitis B using oral antiviral therapy alone

scientific article published on 20 July 2015

Patterns of hepatitis B surface antigen decline and HBV DNA suppression in Asian treatment-experienced chronic hepatitis B patients after three years of tenofovir treatment.

scientific article published on 17 June 2013

Pharmacokinetic evaluation of besifovir for the treatment of HBV infection

scientific article published on 13 December 2017

Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B.

scientific article published on 26 August 2013

Prediction of hepatocellular carcinoma development by aminotransferase to platelet ratio index in primary biliary cholangitis

scientific article published in November 2017

Prevalence of occult hepatitis B infection in a highly endemic area for chronic hepatitis B: a study of a large blood donor population.

scientific article published on 30 July 2010

Prevention and management of hepatitis B virus reactivation in cancer patients

scientific article

Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection.

scientific article published on December 2013

Profile of pre-S deletions in the natural history of chronic hepatitis B infection

scientific article published on 01 November 2010

Quantitative Hepatitis B Surface Antigen Levels in Patients With Chronic Hepatitis B After 2 Years of Entecavir Treatment

article

Real-life efficacy and safety of paritaprevir/ritonavir, ombitasvir, and dasabuvir in chronic hepatitis C patients in Hong Kong

scientific article published on 21 November 2016

Reduction of Hepatitis B Surface Antigen and Covalently Closed Circular DNA by Nucleos(t)ide Analogues of Different Potency

scientific article published on 01 February 2013

Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B.

scientific article published on 14 September 2016

Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy

scientific article published on 24 July 2013

Reduction of liver stiffness following resolution of acute flares of chronic hepatitis B.

scientific article published on 24 July 2010

Relation of Tricuspid Regurgitation to Liver Stiffness Measured by Transient Elastography in Patients With Left-Sided Cardiac Valve Disease.

scientific article published on 7 December 2015

Relationship between HBsAg, HBcrAg and hepatocellular carcinoma in patients with undetectable HBV DNA under nucleos(t)ide therapy

scientific article published on 10 February 2017

Reply to Liao et al.

scientific article published on 3 May 2013

Reversal of Protein-Losing Enteropathy by Liver Transplantation

scientific article published on 01 January 2003

Review article: hepatitis B core-related antigen (HBcrAg): an emerging marker for chronic hepatitis B virus infection.

scientific article published on 16 October 2017

Review article: long-term safety of oral anti-viral treatment for chronic hepatitis B.

scientific article published on 22 January 2018

Risk Factors and Post-Resection Independent Predictive Score for the Recurrence of Hepatitis B-Related Hepatocellular Carcinoma ⬇️

scientific article

Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score.

scientific article published on 14 April 2011

Role of HLA-DP polymorphisms on chronicity and disease activity of hepatitis B infection in Southern Chinese

scientific article

Role of hepatitis B core protein in HBV transcription and recruitment of histone acetyltransferases to cccDNA minichromosome.

scientific article published on 9 May 2017

Role of serum HBV RNA and hepatitis B surface antigen levels in identifying Asian patients with chronic hepatitis B suitable for entecavir cessation

scientific article published on 05 August 2020

Role of serum M2BPGi levels on diagnosing significant liver fibrosis and cirrhosis in treated patients with chronic hepatitis B virus infection.

scientific article published on 19 June 2018

Sequence variations of full-length hepatitis B virus genomes in Chinese patients with HBsAg-negative hepatitis B infection.

scientific article

Serum Mac-2-binding protein glycosylation isomer and risk of hepatocellular carcinoma in entecavir-treated chronic hepatitis B patients.

scientific article published on 20 February 2019

Serum hepatitis B surface antigen (HBsAg) kinetics in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B.

scientific article published on 4 May 2012

Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome

scientific article published on September 2011

Significance of HBV DNA levels in liver histology of HBeAg and Anti-HBe positive patients with chronic hepatitis B.

scientific article published in October 2004

Stability of hepatitis B surface antigen over time: Implications for studies using stored sera

article

T1653 mutation in the box alpha increases the risk of hepatocellular carcinoma in patients with chronic hepatitis B virus genotype C infection

scientific article

Tenofovir disoproxil fumarate for the treatment of chronic hepatitis B monoinfection.

scientific article published on 19 June 2011

Territory-wide population-based study of chronic hepatitis C infection and implications for hepatitis elimination in Hong Kong

scientific article published on 30 July 2018

The Effect of Interferon-Free Regimens on Health-Related Quality of Life in East Asian Patients with Chronic Hepatitis C.

scientific article published on 2 December 2017

The Effects of IL-28B and ITPA polymorphisms on treatment of hepatitis C virus genotype 6.

scientific article published in May 2011

The role of interleukin-27 in predicting spontaneous HBeAg seroconversion in chronic hepatitis B infection

scientific article published on 23 January 2017

The use of transient elastography in the management of chronic hepatitis B.

scientific article published on 22 June 2011

Three Years of Continuous Entecavir Therapy in Treatment-Naïve Chronic Hepatitis B Patients: VIRAL Suppression, Viral Resistance and Clinical Safety

article

Treatment cessation of entecavir in Asian patients with hepatitis B e antigen negative chronic hepatitis B: a multicentre prospective study

article

Trends in liver transplantation for chronic hepatitis B in the era of highly potent antiviral therapies over the past two decades

scientific article published on 11 July 2020

Two-year treatment outcome of chronic hepatitis B infection treated with besifovir vs. entecavir: results from a multicentre study.

scientific article published on 25 October 2014

Use of liver stiffness measurement for liver resection surgery: correlation with indocyanine green clearance testing and post-operative outcome.

scientific article

Wisteria floribunda agglutinin-positive human Mac-2 binding protein predicts liver cancer development in chronic hepatitis B patients under antiviral treatment

scientific article published on 7 May 2017

List of works by Man-Fung Yuen

A large case-control study on the predictability of hepatitis B surface antigen levels three years before hepatitis B surface antigen seroclearance.

A large real-world cohort study examining the effects of long-term entecavir on hepatocellular carcinoma and HBsAg seroclearance

A new model using routinely available clinical parameters to predict significant liver fibrosis in chronic hepatitis B

An update on the toxicological considerations for protease inhibitors used for hepatitis C infection.

Application of coamplification at lower denaturation temperature-PCR sequencing for early detection of antiviral drug resistance mutations of hepatitis B virus.

Artificial neural network accurately predicts hepatitis B surface antigen seroclearance.

Association Between Hepatic Steatosis, Measured by Controlled Attenuation Parameter, and Fibrosis Burden in Chronic Hepatitis B.

Association of Hepatitis B Core-Related Antigen With Hepatitis B Virus Reactivation in Occult Viral Carriers Undergoing High-Risk Immunosuppressive Therapy.

Association of adipokines with hepatic steatosis and fibrosis in chronic hepatitis B patients on long-term nucleoside analogue

Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in chronic hepatitis B.

Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after 5 years of entecavir treatment

Chronic Hepatitis B Virus Infection: Disease Revisit and Management Recommendations

Clinical outcome and virologic profiles of severe hepatitis B exacerbation due to YMDD mutations.

Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma.

Combination of baseline parameters and on-treatment hepatitis B virus DNA levels to start and continue patients with lamivudine therapy.

Correlation of liver stiffness and histological features in healthy persons and in patients with occult hepatitis B, chronic active hepatitis B, or hepatitis B cirrhosis.

Correlation of serum Mac-2-binding protein glycosylation isomer (M2BPGi) and liver stiffness in chronic hepatitis B infection

Corrigendum to “Profiles of HBV DNA in a large population of Chinese patients with chronic hepatitis B: Implications for antiviral therapy” [J Hepatol 2011;54:195–200]

Current Antiviral Therapy of Chronic Hepatitis B: Efficacy and Safety

DNA polymerase inhibitors for treating hepatitis B: a safety evaluation.

Deep sequencing analysis of quasispecies in the HBV pre-S region and its association with hepatocellular carcinoma.

Defining normal liver stiffness range in a normal healthy Chinese population without liver disease

Development of predisposition, injury, response, organ failure model for predicting acute kidney injury in acute on chronic liver failure.

East Asia expert opinion on treatment initiation for chronic hepatitis B

Emerging drugs for the treatment of hepatitis B.

Entecavir Reduced Serum Hepatitis B Core-Related Antigen in Chronic Hepatitis B Patients with Hepatocellular Carcinoma

Epidemiology and natural history of Wilson's disease in the Chinese: A territory-based study in Hong Kong between 2000 and 2016.

Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region

Estradiol induces apoptosis via activation of miRNA-23a and p53: implication for gender difference in liver cancer development.

Evidence of serologic activity in chronic hepatitis B after surface antigen (HBsAg) seroclearance documented by conventional HBsAg assay

Evolutionary Changes of Hepatitis B Virus Pre-S Mutations Prior to Development of Hepatocellular Carcinoma

Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment.

Fibrosis evolution in chronic hepatitis B e antigen-negative patients across a 10-year interval

Future prevention and treatment of chronic hepatitis B infection.

Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection.

HBV RNA profiles in chronic hepatitis B patients under different disease phases and anti-viral therapy

HBsAg seroclearance in chronic hepatitis B in the Chinese: virological, histological, and clinical aspects.

Hepatitis B Surface Antigen Seroclearance: Relationship to Hepatitis B e-Antigen Seroclearance and Hepatitis B e-Antigen-Negative Hepatitis

Hepatitis B core protein as a therapeutic target.

Hepatitis B core-related antigen levels after HBeAg seroconversion is associated with the development of hepatocellular carcinoma

Hepatitis B reactivation in occult viral carriers undergoing hematopoietic stem cell transplantation: A prospective study.

Hepatitis B reactivation in patients with previous hepatitis B virus exposure undergoing rituximab-containing chemotherapy for lymphoma: a prospective study.

Hepatitis B surface antigen levels after hepatitis B e-antigen seroclearance: a longitudinal follow-up study

Hepatitis B surface antigen seroclearance during nucleoside analogue therapy: surface antigen kinetics, outcomes, and durability.

Hepatitis B virus core-related antigen as a surrogate marker for covalently closed circular DNA.

Hepatitis B virus full-length genomic mutations and quasispecies in hepatocellular carcinoma

Hepatitis B: treatment choice and monitoring for response and resistance.

High hepatitis B surface antigen levels predict insignificant fibrosis in hepatitis B e antigen positive chronic hepatitis B.

Interleukin-1β increases the risk of gastric cancer through induction of aberrant DNA methylation in a mouse model

Inverse relationship between hepatic steatosis and hepatitis B viremia: Results of a large case-control study.

Ketamine-induced cholangiopathy: a case report.

Letter: serum HBcrAg is a useful marker for disease monitoring, predicting treatment response and disease outcome of chronic hepatitis B virus infection-authors' reply

Long Term Outcomes and Predictive Scores for Hepatocellular Carcinoma and HBsAg Seroclearance after HBeAg Seroclearance.

Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease.

Long-term outcomes of entecavir monotherapy for chronic hepatitis B after liver transplantation: Results up to 8 years.

Longitudinal profiles of highly sensitive hepatitis B surface antigen levels: re-evaluation of HBsAg seroclearance.

Longitudinal study of hepatitis activity and viral replication before and after HBeAg seroconversion in chronic hepatitis B patients infected with genotypes B and C.

Model for End-stage Liver Disease with additional criteria to predict short-term mortality in severe flares of chronic hepatitis B

Mutational analysis for Wilson's disease.

New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia

No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.

Nucleoside/nucleotide analogues in the treatment of chronic hepatitis B

Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma.

Oral nucleos(t)ide Analogs Alone After Liver Transplantation in Chronic Hepatitis B with Preexisting rt204 Mutation

Oral nucleoside/nucleotide analogs without hepatitis B immune globulin after liver transplantation for hepatitis B.

Outcomes including liver histology after liver transplantation for chronic hepatitis B using oral antiviral therapy alone

Patterns of hepatitis B surface antigen decline and HBV DNA suppression in Asian treatment-experienced chronic hepatitis B patients after three years of tenofovir treatment.

Pharmacokinetic evaluation of besifovir for the treatment of HBV infection

Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B.

Prediction of hepatocellular carcinoma development by aminotransferase to platelet ratio index in primary biliary cholangitis

Prevalence of occult hepatitis B infection in a highly endemic area for chronic hepatitis B: a study of a large blood donor population.

Prevention and management of hepatitis B virus reactivation in cancer patients

Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection.

Profile of pre-S deletions in the natural history of chronic hepatitis B infection

Quantitative Hepatitis B Surface Antigen Levels in Patients With Chronic Hepatitis B After 2 Years of Entecavir Treatment

Real-life efficacy and safety of paritaprevir/ritonavir, ombitasvir, and dasabuvir in chronic hepatitis C patients in Hong Kong

Reduction of Hepatitis B Surface Antigen and Covalently Closed Circular DNA by Nucleos(t)ide Analogues of Different Potency

Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B.

Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy