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List of works by Thomas Haselhorst

A secondary sialic acid binding site on influenza virus neuraminidase: fact or fiction?

scientific article published on 26 January 2012

All major cholesterol-dependent cytolysins use glycans as cellular receptors

scientific article published on 22 May 2020

Avian influenza H5-containing virus-like particles (VLPs): host-cell receptor specificity by STD NMR spectroscopy.

scientific article published in January 2008

C-4 modified sialosides enhance binding to Siglec-2 (CD22): towards potent Siglec inhibitors for immunoglycotherapy

scientific article published on 25 February 2013

CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function

scientific article published on 11 July 2018

Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles.

scientific article published on October 2010

Characterisation of CMP-sialic acid transporter substrate recognition.

scientific article published on 6 September 2013

Conformational analysis of a Chlamydia-specific disaccharide alpha-Kdo-(2-->8)-alpha-Kdo-(2-->O)-allyl in aqueous solution and bound to a monoclonal antibody: observation of intermolecular transfer NOEs.

scientific article

Defining a substrate-binding model of a polysialyltransferase

scientific article published on 05 September 2013

Detection of ligand binding to nucleotide sugar transporters by STD NMR spectroscopy.

scientific article published in November 2008

Direct detection of ligand binding to Sepharose-immobilised protein using saturation transfer double difference (STDD) NMR spectroscopy

scientific article published on 06 June 2007

Direct investigation of the Aspergillus GDP-mannose transporter by STD NMR spectroscopy

scientific article published on 23 September 2011

Endosialidase NF appears to bind polySia DP5 in a helical conformation.

scientific article published in December 2006

Enhancing Vaccine Efficacy by Engineering a Complex Synthetic Peptide To Become a Super Immunogen

scientific article published on 13 September 2017

Exploring human parainfluenza virus type-1 hemagglutinin-neuraminidase as a target for inhibitor discovery

scientific article published on 8 September 2014

Glycobiology of Human Fungal Pathogens: New Avenues for Drug Development

scientific article published on 30 October 2019

Influence of an ER-retention signal on the N-glycosylation of recombinant human α-L-iduronidase generated in seeds of Arabidopsis.

scientific article published on 23 March 2012

Investigation of the binding and cleavage characteristics of N1 neuraminidases from avian, seasonal, and pandemic influenza viruses using saturation transfer difference nuclear magnetic resonance.

scientific article

Leishmania UDP-sugar pyrophosphorylase: the missing link in galactose salvage?

scientific article

Molecular cloning of the Leishmania major UDP-glucose pyrophosphorylase, functional characterization, and ligand binding analyses using NMR spectroscopy.

scientific article published on 12 April 2006

NMR spectroscopic and molecular modeling investigations of the trans-sialidase from Trypanosoma cruzi.

scientific article

Neisseria meningitidis serogroup B polysialyltransferase: insights into substrate binding.

scientific article published in January 2010

Probing a CMP-Kdn synthetase by 1H, 31P, and STD NMR spectroscopy.

scientific article published in February 2005

Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease

scientific article published in Nature Communications

Proteolytic release of the intramolecular chaperone domain confers processivity to endosialidase F.

scientific article published on 3 February 2009

Relative roles of GM1 ganglioside, N-acylneuraminic acids, and α2β1 integrin in mediating rotavirus infection

scientific article published on 05 February 2014

Saturation transfer difference (STD) 1H-NMR experiments and in silico docking experiments to probe the binding of N-acetylneuraminic acid and derivatives to Vibrio cholerae sialidase

scientific article

Saturation transfer difference NMR spectroscopy as a technique to investigate protein-carbohydrate interactions in solution.

scientific article published on January 2009

Self-derived structure-disrupting peptides targeting methionine aminopeptidase in pathogenic bacteria: a new strategy to generate antimicrobial peptides

scientific article published on 27 September 2018

Structure and function of nucleotide sugar transporters: Current progress

scientific article published on 11 June 2014

Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin-neuraminidase inhibitors

scientific article

Unravelling the Role of O-glycans in Influenza A Virus Infection

scientific article published in Scientific Reports