Search filters

List of works by Franciszek Sączewski

1-[(Imidazolidin-2-yl)imino]-1H-indoles as new hypotensive agents: synthesis and in vitro and in vivo biological studies

scientific article published on 27 August 2016

1-[(Imidazolidin-2-yl)imino]indazole. Highly alpha 2/I1 selective agonist: synthesis, X-ray structure, and biological activity

scientific article published on 3 June 2008

1H-Benzimidazole-2-carboxylic acid monohydrate

2-(4,5-Dihydro-1H-imidazol-2-yl)indazole (indazim) derivatives as selective I2 imidazoline receptor ligands ⬇️

scientific article published on October 1, 2003

2-Amino-4,5-dihydro-1H-imidazol-3-ium 7,8-dihydroimidazo[1,2-c][1,3,5]thiadiazine-2,4(6H)-dithione(1−) dimethylformamide disolvate

2-Amino-6-(1-imidazolylmethyl)-4-(3,5,5-trimethyl-2-pyrazolin-1-yl)-1,3,5-triazine and 2-amino-6-(1-benzimidazolylmethyl)-4-(3,5,5-trimethyl-2-pyrazolin-1-yl)-1,3,5-triazine hemihydrate

scientific article published on 14 November 2003

2-Chloro-4,5-dihydroimidazole. Part VII. Reactions with carbon disulfide and potassium O-alkyl dithiocarbonates. Synthesis and transformations of 2,3,7,8-tetrahydro-5H-diimidazo[2,1-b : 1′,2′-e][1,3,5]thiadiazine-5-thione

3-[(Imidazolidin-2-yl)imino]indazole ligands with selectivity for the α2-adrenoceptor compared to the imidazoline I1 receptor

scientific article published on 11 November 2010

5-Methyl-3,6,7,8a-tetra-hydro-2H-diimidazo[1,2-c:1',2'-e]pyrido[1,2-a][1,3,5]triazin-5-ium iodide

scientific article published on 29 May 2010

A new imidazoline-containing Bunte salt: synthesis, molecular and electronic structure

A new type of mixed anhydride and its applications to the synthesis of 7-substituted 8-chloro-5,5-dioxoimidazo[1,2-b][1,4,2]benzodithiazines with in vitro antitumor activity

scientific article published on January 2002

A search for new antihypertensive agents. II. Circulatory activity and selection of structures among 2-methylbenzimidazole derivatives

scientific article published on 01 July 1987

Anion-pi interactions in cyanuric acids: a combined crystallographic and computational study

scientific article published in November 2005

Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors

scientific article

Are Alpha-2D Adrenoceptor Subtypes Involved in Rat Mydriasis Evoked by New Imidazoline Derivatives: Marsanidine and 7-Methylmarsanidine?

scientific article

Biological activities of guanidine compounds

scientific article published on October 2009

Biological activities of guanidine compounds, 2008 - 2012 update

scientific article published on 25 April 2013

COMPARISON OF THE EFFECTS OF MARSANIDINE DERIVATIVES ON RAT CARDIOVASCULAR SYSTEM

Carbon disulfide promoted reactions of 2-chloro-4,5-dihydro-imidazole with some N-nucleophiles

scientific article

Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors

scientific article published on 30 June 2006

Carbonic anhydrase inhibitors. Selective inhibition of human tumor-associated isozymes IX and XII and cytosolic isozymes I and II with some substituted-2-mercapto-benzenesulfonamides

Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.

scientific article

Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides

scientific article published on 12 February 2010

Circulatory effect of TCS-80, a new imidazoline compound, in rats.

scientific article

Comparative pharmacodynamic analysis of imidazoline compounds using rat model of ocular mydriasis with a test of quantitative structure-activity relationships.

scientific article published on 6 April 2017

Copper(II)-assisted hydrolysis of cyclic ureas: Transformation of 1-(pyridin-2-yl)-2,3,7,8-tetrahydro-1 H -imidazo[2,1- b ][1,3,5]triazepin-5(6 H )-ones into N 1 -[1-(pyridin-2-yl)imidazolidin-2-ylidene]-ethane-1,2-diamine ligands

Crystal and molecular structure of 3-(4-chlorobenzoylimino)-5,6-dihydro-3H-imidazo[2,1-c]-1,2,4-dithiazole

Experimental and theoretical studies on the tautomerism and reactivity of isoxazolo[3,4-b]quinolin-3(1H)-ones

First StableO-Amidinylhydroxylamines and Their Transformations into Sulfenamides by Intramolecular 1,5-O→S Amine Migration

Fluorinated analogues of marsanidine, a highly α2-AR/imidazoline I1 binding site-selective hypotensive agent. Synthesis and biological activities

scientific article published on 28 September 2014

Hybrid Molecules Composed of 2,4-Diamino-1,3,5-triazines and 2-Imino-Coumarins and Coumarins. Synthesis and Cytotoxic Properties

scientific article published on 03 July 2018

Imidazoline scaffold in medicinal chemistry: a patent review (2012-2015).

scientific article

Marsanidine and 7-Me-marsanidine, the new hypotensive imidazolines augment sodium and urine excretion in rats.

scientific article published in January 2013

N-Amidinio-3,5,5-trimethyl-2-pyrazoline-1-carboxamidine chloride (BPC-151), an oral hypoglycaemic agent

Polymeric (anion-π)n interactions in crystals of 2-(2,4,6-trioxo-[1,3,5]triazinan-1-yl)ethylammonium iodide

Preparation, structure and affinity for imidazoline I2 receptors and alpha2-adrenoceptors of 1-[(4,5-dihydroimidazolidin-2-yl)imino]indan-2-ols

scientific article published in November 2005

Radiosynthesis and Preclinical Evaluation of an α2A-Adrenoceptor Tracer Candidate, 6-[18F]Fluoro-marsanidine

scientific article published on 01 October 2019

Structural diversity of copper(II) complexes with N-(2-pyridyl)imidazolidin-2-ones(thiones) and their in vitro antitumor activity.

scientific article

Structure of New Imidazoline Derivatives and Their Cardiovascular Effect in Ratsa

scientific article published on 01 June 1999

Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.

scientific article published on 5 December 2007

Studies of benzimidazole derivatives. XIII. Synthesis of various 2-alpha-hydroxy- and 2-beta-hydroxyalkyl-benzimidazoles

scientific article

Syntheses and biological activities of 2-(adamantylmethyl)benzimidazoles and -imidazolines

scientific article published on 01 September 1986

Synthesis and Fluorescent Properties of Novel Isoquinoline Derivatives

scientific article published on 10 November 2019

Synthesis and Preliminary Cytotoxicity Studies of 1-[1-(4,5-Dihydrooxazol-2-yl)-1H-indazol-3-yl]-3-phenylurea and 3-phenylthiourea Derivatives

scientific article published on 6 March 2017

Synthesis and anti-HIV-1 activity of a novel series of 1,4,2-benzodithiazine-dioxides

scientific article published on 14 August 2006

Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines

scientific article published on 4 March 2008

Synthesis and antitumor activity of novel 2-amino-4-(3,5,5-trimethyl-2-pyrazolino)-1,3,5-triazine derivatives

scientific article published in September 2002

Synthesis and biological activities of 2-[(heteroaryl)methyl]imidazolines

scientific article published on 25 November 2011

Synthesis and biological activities of some 7,8-dihydroimidazo[1,2-a]-1,3,5-triazine derivatives

scientific article published on 01 May 1995

Synthesis and cytotoxic activity of imidazo[1,2-a]-1,3,5-triazine analogues of 6-mercaptopurine

scientific article

Synthesis and in vitro anti-tumor activity of N-{1-[(3-thioxo-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-ylthio)thiocarbonyl]-2-imidazolidene}arylsulfonamides

scientific article published on 8 May 2006

Synthesis and structure of novel 2,3, 5,6-tetrahydro-1H-imidazo[2,1-b][1,3,5]benzotriazepines with vasocontractile activity in rabbit aortic rings

scientific article published in November 2003

Synthesis of 2,3,5,6-tetrahydro-3H-imidazo[2,1-b] [1,3,5]benzotriazepines and their oxidative ring contraction into 1-(4,5-dihydro-1H-imidazol-2-yl)-1H-benzimidazoles

scientific article

Synthesis of HBB analogs with potential antiviral activity

scientific article published on 01 January 1978

Synthesis of N-(2-pyridyl)imidazolidin-2-ones and 1-(2-pyridyl)-2,3,7,8-tetrahydro-1H-imidazo[2,1-b][1,3,5]triazepin-5(6H)-ones with potential biological activities

Synthesis of novel 3-amino-2-(4-chloro-2-mercaptobenzenesulfonyl)-guanidine derivatives as potential antitumor agents

scientific article

Synthesis of novel aryl(heteroaryl)sulfonyl ureas of possible biological interest

scientific article published on 26 February 2010

Synthesis, Structure and Cytotoxicity Testing of Novel 7-(4,5-dihydro-1<i>H</i>-imidazol-2-yl)-2-aryl-6,7-dihydro-2<i>H</i>-imidazo[2,1-<i>c</i>][1,2,4]triazol-3(5<i>H</i>)-Imine Derivatives

scientific article published on 14 December 2020

Synthesis, Structure and Transformations of 2-Iminoimidazolidines into Novel Fused Heterocyclic Ring Systems

Synthesis, Structure, Chemical Stability, and In Vitro Cytotoxic Properties of Novel Quinoline-3-Carbaldehyde Hydrazones Bearing a 1,2,4-Triazole or Benzotriazole Moiety

scientific article published on 20 June 2018

Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles

scientific article published on June 2004

Synthesis, X-ray structure analysis and computational studies of novel bis(thiocarbamoyl) disulfides with non-covalent S⋯N and S⋯S interactions

Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives

scientific article published on 11 September 2007

Synthesis, antitumor and anti-HIV activities of benzodithiazine-dioxides

scientific article published on 6 January 2006

Synthesis, antiviral, and anti-HIV-1 integrase activities of 3-aroyl-1,1-dioxo-1,4,2-benzodithiazines

scientific article published on July 2004

Synthesis, crystal structure and biological activities of copper(II) complexes with chelating bidentate 2-substituted benzimidazole ligands

scientific article published on 22 April 2006

Synthesis, crystal structure, cytotoxic and superoxide dismutase activities of copper(II) complexes of N-(4,5-dihydroimidazol-2-yl)azoles

scientific article

Synthesis, molecular structure and anticancer activity of 1-allyl-3-amino-2-(4-chloro-2-mercaptobenzenesulphonyl)guanidine derivatives

scientific article published in April 2002

Synthesis, molecular structure and reactivity of 5-methylidene-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolines

scientific article published on 28 February 2004

Synthesis, molecular structure, and applications of 2-hydroxylamino-4,5-dihydroimidazolium-O-sulfonate to the synthesis of novel heterocyclic ring systems

scientific article

Synthesis, structural characterization and antitumor activity of novel 2,4-diamino-1,3,5-triazine derivatives

scientific article published on 01 December 2000

Synthesis, structural characterization and in vitro antitumor activity of 4-dimethylaminopyridinium (6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)methanides

scientific article published on November 2003

Synthesis, structural characterization and in vitro antitumor activity of novel 6-chloro-1,1-dioxo-1,4,2-benzodithiazie derivatives

scientific article published in August 2003

Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides

scientific article published on 2 February 2007

Synthesis, structure and antiaggregatory effects of some N-(4,5-dihydro-1H-imidazol-2-yl)indoles

scientific article

Synthesis, structure and antiaggregatory effects of some α-hydroxy analogues of 2-aryliminoimidazolines in human platelets

Synthesis, structure and anticancer activity of novel 2,4-diamino-1,3,5-triazine derivatives.

scientific article published on 27 December 2005

Synthesis, structure and anticancer activity of novel alkenyl-1,3,5-triazine derivatives

scientific article published on 15 March 2006

Synthesis, structure, and binding of some 2-imidazolines to rat brain alfa-1 and alfa-2-adrenergic receptors

scientific article

Synthesis, structure, and biological activities of some N-(4,5-dihydro-1H-imidazol-2-yl)-1,3-dihydrobenzimidazole derivatives

scientific article published on 01 July 1998

Synthesis, transformations and tuberculostatic activity of 1-(N-aroylthiocarbamoyl)imidiazolidine-2-thiones

scientific article published on 01 January 1993

The effect of 7-fluoro-marsanidine, a novel α2-adrenoceptor agonist, on extracellular noradrenaline in rat frontal cortex: a microdialysis study

scientific article published on 27 January 2015

Transfer of SAR information from hypotensive indazole to indole derivatives acting at α-adrenergic receptors: In vitro and in vivo studies

scientific article published on 14 March 2016

Vagotomy reveals the importance of the imidazoline receptors in the cardiovascular effects of marsanidine and 7-ME-marsanidine in rats

scientific article published on 06 June 2014

α-Iminohydroxylamine-α-aminonitrone tautomerism: a 1∶1 mixture of two tautomeric forms in crystals of N-(4,5-dihydro-1H-imidazol-2-yl)-N-phenyl-hydroxylamine

Paulina is supported by:

About Paulina

Help