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List of works by Lucyna Antkiewicz-Michaluk

1,2,3,4-Tetrahydroisoquinoline produces an antidepressant-like effect in the forced swim test and chronic mild stress model of depression in the rat: Neurochemical correlates

scientific article

1-Benzyl-1,2,3,4-tetrahydroisoquinoline, an endogenous neurotoxic compound, disturbs the behavioral and biochemical effects of L-DOPA: in vivo and ex vivo studies in the rat.

scientific article

1-Benzyl-1,2,3,4-tetrahydroisoquinoline, an endogenous parkinsonism-inducing toxin, strongly potentiates MAO-dependent dopamine oxidation and impairs dopamine release: ex vivo and in vivo neurochemical studies

scientific article published on January 2009

1-Methyl-1,2,3,4-tetrahydroisoquinoline - The toxicological research on an exo/endogenous amine with antidepressant-like activity - In vivo, in vitro and in silico studies

scientific article published on 09 July 2019

1-Methyl-1,2,3,4-tetrahydroisoquinoline and established uncompetitive NMDA receptor antagonists induce tolerance to excitotoxicity.

scientific article published on November 2010

1-Methyl-1,2,3,4-tetrahydroisoquinoline antagonizes a rise in brain dopamine metabolism, glutamate release in frontal cortex and locomotor hyperactivity produced by MK-801 but not the disruptions of prepulse inhibition, and impairment of working mem

scientific article published in August 2009

1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model

scientific article

1-Methyl-1,2,3,4-tetrahydroisoquinoline, an endogenous Neuroprotectant and MAO inhibitor with antidepressant-like properties in the rat.

scientific article published on 25 September 2013

1-Methyl-1,2,3,4-tetrahydroisoquinoline, an endogenous amine with unexpected mechanism of action: new vistas of therapeutic application

scientific article published on 30 May 2013

1-methyl-1,2,3,4-tetrahydroisoquinoline protects against rotenone-induced mortality and biochemical changes in rat brain

scientific article published in April 2003

1MeTIQ provides protection against Aβ-induced reduction of surface expression of synaptic proteins and inhibits H₂O₂-induced oxidative stress in primary hippocampal neurons.

scientific article

3-Methoxytyramine, an extraneuronal dopamine metabolite plays a physiological role in the brain as an inhibitory regulator of catecholaminergic activity.

scientific article

3H-dihydromorphine binding sites in subcellular fractions of rat striatum

scientific article published on January 1, 1982

5-Hydroxytryptamine-like properties of m-chlorophenylpiperazine: comparison with quipazine

scientific article published on 01 March 1980

A comparison of locomotor responses to some psychotropic drugs and cerebral receptors in the Acomys cahirinus and the laboratory mouse.

scientific article

A possible physiological role for cerebral tetrahydroisoquinolines

scientific article

Action of antidepressant neuroleptics, chlorprothixene and levomepromazine, on the central noradrenergic system: comparison with other antidepressants

scientific article published on 01 September 1985

Acute treatment with doxorubicin induced neurochemical impairment of the function of dopamine system in rat brain structures

scientific article

Alpha up-beta down adrenergic regulation: a possible mechanism of action of antidepressant treatments

scientific article published on 01 March 1984

Alpha-adrenergic receptor changes during antidepressant treatment.

scientific article published in January 1985

An endogenous neuroprotectant substance, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), prevents the behavioral and neurochemical effects of cocaine reinstatement in drug-dependent rats

scientific article published on 10 August 2006

Anticonvulsant activity of some xanthone derivatives.

scientific article published on 25 June 2008

Anticonvulsant evaluation of aminoalkanol derivatives of 2- and 4-methylxanthone.

scientific article

Antidepressant profile of 9-methyl-2[-3-(4-phenyl-1-piperazinylpropyl)]-1,2,3,4-tetrahydro-beta- carbolin-1-one (B-193)

scientific article published on 01 July 1989

Antidepressant-Like Effect of the Endogenous Neuroprotective Amine, 1MeTIQ in Clonidine-Induced Depression: Behavioral and Neurochemical Studies in Rats

scientific article

Antidepressant-like activity of the endogenous amine, 1-methyl-1,2,3,4-tetrahydroisoquinoline in the behavioral despair test in the rat, and its neurochemical correlates: a comparison with the classical antidepressant, imipramine

scientific article

Antidepressant-like effect of 1,2,3,4-tetrahydroisoquinoline and its methyl derivative in animal models of depression

scientific article

Antidepressant-like effect of tetrahydroisoquinoline amines in the animal model of depressive disorder induced by repeated administration of a low dose of reserpine: behavioral and neurochemical studies in the rat.

scientific article

Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action

scientific article

Antidopaminergic effects of 1,2,3,4-tetrahydroisoquinoline and salsolinol

scientific article published on 01 January 2000

Behavioural and biochemical studies of citalopram and WAY 100635 in rat chronic mild stress model

scientific article published in May 2002

Both stereoselective (R)- and (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline enantiomers protect striatal terminals against rotenone-induced suppression of dopamine release

scientific article

Ca2+ channel blockade prevents lysergic acid diethylamide-induced changes in dopamine and serotonin metabolism

scientific article published in July 1997

Central action of ergometrine

scientific article published in November 1976

Changes in Monoaminergic Neurotransmission in an Animal Model of Osteoarthritis: The Role of Endocannabinoid Signaling

Chronic administration of antidepressant drugs increases the density of cortical [3H]prazosin binding sites in the rat.

scientific article published in September 1984

Chronic electroconvulsive treatment counteracts cortical beta-adrenoceptor upregulation induced by morphine abstinence

scientific article published on March 1, 1991

Chronic electroconvulsive treatment enhances the density of [3H]prazosin binding sites in the central nervous system of the rat.

scientific article

Chronic impairment of the vagus nerve function leads to inhibition of dopamine but not serotonin neurons in rat brain structures.

scientific article

Chronic salsolinol administration prevents the behavioral and neurochemical effects of L-DOPA in rats

scientific article

Chronic treatment with the potential antidepressant drug rolipram: the effect on the behavioural responses to adrenergic and dopaminergic receptor agonists with some biochemical correlates

article

Co-administration of nifedipine with neuroleptics prevents development of activity changes during withdrawal

scientific article published on 01 January 1994

Combined brain Fe, Cu, Zn and neurometabolite analysis - a new methodology for unraveling the efficacy of transcranial direct current stimulation (tDCS) in appetite control.

scientific article published on 31 January 2018

Comparative behavioral and neurochemical studies of R- and S-1-methyl-1,2,3,4-tetrahydroisoquinoline stereoisomers in the rat.

scientific article

Comparison of the Effects of Acute and Chronic Administration of Tetrahydroisoquinoline Amines on the In Vivo Dopamine Release: A Microdialysis Study in the Rat Striatum

scientific article published on 27 August 2016

Comparison of the effects of 1MeTIQ and olanzapine on performance in the elevated plus maze test and monoamine metabolism in the brain after ketamine treatment.

scientific article

Concentration-dependent opposite effects of 1-benzyl-1,2,3,4-tetrahydroisoquinoline on markers of apoptosis: in vitro and ex vivo studies

scientific article

Conditioned rewarding stimulus associated with cocaine self-administration reverses the depression of catecholamine brain systems following cocaine withdrawal in rats

scientific article published on 7 June 2005

Conditions of application of repeated transcranial magnetic stimulation to rats may mask the effects of the treatment.

scientific article published in November 2001

Cortical dihydropyridine binding sites and a behavioral syndrome in morphine-abstinent rats

scientific article published in May 1990

Differences between haloperidol- and pimozide-induced withdrawal syndrome: a role for Ca2+ channels

scientific article published on December 1995

Differences in effects of Ca2+ channel antagonists on dopamine metabolism in the limbic and extrapyramidal dopaminergic structures

scientific article

Different action on dopamine catabolic pathways of two endogenous 1,2,3,4-tetrahydroisoquinolines with similar antidopaminergic properties

scientific article

Different effects of chronic administration of haloperidol and pimozide on dopamine metabolism in the rat brain

scientific article published in October 1996

Different effects of intranigral and intrastriatal administration of the proteasome inhibitor lactacystin on typical neurochemical and histological markers of Parkinson's disease in rats.

scientific article published on 16 March 2011

Differential involvement of voltage-dependent calcium channels in apomorphine-induced hypermotility and stereotypy

scientific article published on 01 January 1994

Dopamine receptors in the striatum and limbic system of various strains of mice: relation to differences in responses to apomorphine

scientific article

Dopaminergic and serotonergic effects of ergometrine

scientific article published on May 1, 1977

Effect of 1,2,3,4,-tetrahydroisoquinoline administration under conditions of CYP2D inhibition on dopamine metabolism, level of tyrosine hydroxylase protein and the binding of [3H]GBR 12,935 to dopamine transporter in the rat nigrostriatal, dopaminer

scientific article published in May 2004

Effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the protective action of various antiepileptic drugs in the maximal electroshock-induced seizure model: a type II isobolographic analysis.

scientific article published on 07 June 2013

Effect of NOS inhibitor on forced swim test and neurotransmitters turnover in the mouse brain.

scientific article published in November 2001

Effect of acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline on muscle tone, metabolism of dopamine in the striatum and tyrosine hydroxylase immunocytochemistry in the substantia nigra, in rats

scientific article

Effect of electroconvulsive treatment on cerebral opioid receptors in the rat: changes in delta but not mu receptors

scientific article published in November 1984

Effect of repetitive electroconvulsive treatment on sensitivity to pain and on [3H]nitrendipine binding sites in cortical and hippocampal membranes

scientific article published on 01 January 1990

Effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the behavioral effects of cocaine in rats

scientific article

Effects of chronically administered antidepressants and electroconvulsive treatment on cerebral neurotransmitter receptors in rodents with 'model depression'.

scientific article published in January 1986

Effects of the noradrenergic neurotoxin DSP-4 on the expression of α1-adrenoceptor subtypes after antidepressant treatment

scientific article published on January 1, 2011

Effects of various Ca2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat.

scientific article published in July 1998

Endogenous risk factors in Parkinson's disease: dopamine and tetrahydroisoquinolines

scientific article

Erratum to: Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson's Disease

scientific article published on 01 August 2016

High doses of morphine do not change characteristics of the cerebral catecholamine receptors in the rat.

scientific article published on July 1988

Immediate and "day-after" effects of morphine on dopamine and serotonin metabolism in various structures of the rat brain

scientific article published on 01 July 1995

Important role of 3-methoxytyramine in the inhibition of cocaine sensitization by 1-methyl-1,2,3,4-tetrahydroisoquinoline: an in vivo microdialysis study

scientific article published on November 2010

Increase in rat cortical [3H]naloxone binding site density after chronic administration of antidepressant agents

scientific article published in June 1984

Increase in salsolinol level in the cerebrospinal fluid of parkinsonian patients is related to dementia: advantage of a new high-performance liquid chromatography methodology

scientific article published in September 1997

Increased low-affinity 3H-spiroperidol binding to rat cortical membranes after chronic antidepressant treatments

scientific article published in May 1985

Increased striatal neuropeptide Y immunoreactivity and its modulation by deprenyl, clonidine and L-dopa in MPTP-treated mice

scientific article

Influence of benzodiazepines on turnover of serotonin in cerebral structures in normal and aggressive rats

scientific article published on January 1, 1975

Inhibition of rodent brain monoamine oxidase and tyrosine hydroxylase by endogenous compounds - 1,2,3,4-tetrahydro-isoquinoline alkaloids.

scientific article published in November 2004

Interactions of 1-methyl-1,2,3,4-tetrahydroisoquinoline with lamotrigine, oxcarbazepine, pregabalin, and topiramate in the mouse maximal electroshock-induced seizure model: a type I isobolographic analysis

scientific article published in February 2010

Isobolographic analysis of interactions between 1-methyl-1,2,3,4-tetrahydroisoquinoline and four conventional antiepileptic drugs in the mouse maximal electroshock-induced seizure model

scientific article

Modification of effects of chronic electroconvulsive shock by voltage-dependent Ca2+ channel blockade with nifedipine

scientific article

Molecular characterization and mitochondrial density of a recognition site for peripheral-type benzodiazepine ligands

scientific article published on 01 September 1988

Multiple Administration of Endogenous Amines TIQ and 1MeTIQ Protects Against a 6-OHDA-Induced Essential Fall of Dopamine Release in the Rat Striatum: In Vivo Microdialysis Study

scientific article published on 26 October 2017

Neurochemical changes induced by acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline and salsolinol in dopaminergic structures of rat brain

scientific article published on 01 January 2000

Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson's Disease

scientific article published on 25 August 2015

Nicotine potentiates imipramine-induced effects on catecholamine metabolism: possible relation to antidepressant activity

scientific article

Nicotine produces antidepressant-like actions: Behavioral and neurochemical evidence.

scientific article published in May 2005

Novel antagonists of 5-HT and/or 5-HT receptors affect the brain monoamines metabolism and enhance the anti-immobility activity of different antidepressants in rats

scientific article published on 09 October 2018

Opiate and alpha 1-adrenergic receptors in mice responding to morphine with sedation or with running fit.

scientific article

Opioid-specific recognition sites of the mu- and the delta-type in rat striatum after lesions with kainic acid

scientific article published on July 1984

Opposite effect of simple tetrahydroisoquinolines on amphetamine- and morphine-stimulated locomotor activity in mice

scientific article published in January 2001

Postmortem instability of dopamine and its metabolites in rat striatum and limbic forebrain.

scientific article

Preliminary studies of the adrenergic receptors in the human right atrium

scientific article published on 01 January 1984

Pro-cognitive effect of 1MeTIQ on recognition memory in the ketamine model of schizophrenia in rats: the behavioural and neurochemical effects

scientific article published on 20 February 2020

Prolactin and its receptors in the chronic mild stress rat model of depression

scientific article

Protective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline against dopaminergic neurodegeneration in the extrapyramidal structures produced by intracerebral injection of rotenone

scientific article published on 23 January 2004

Purification and characterization of a protein associated with peripheral-type benzodiazepine binding sites

scientific article published on 01 November 1988

Purification of a novel DBI processing product, DBI39-75, and characterization of its binding site in rat brain

scientific article

Purification, cloning, and expression of a peripheral-type benzodiazepine receptor.

scientific article published on January 1990

Receptor and voltage-operated ion channels in the central nervous system

scientific article published on 01 May 1995

Reduction of morphine dependence and potentiation of analgesia by chronic co-administration of nifedipine

scientific article published in January 1993

Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat.

scientific article published on 30 April 2018

Repeated Transcranial Direct Current Stimulation Induces Behavioral, Metabolic and Neurochemical Effects in Rats on High-Calorie Diet

scientific article published in January 2017

Resilient Phenotype in Chronic Mild Stress Paradigm Is Associated with Altered Expression Levels of miR-18a-5p and Serotonin 5-HT1a Receptor in Dorsal Part of the Hippocampus

scientific article published on 16 May 2019

Role of calcium channels in effects of antidepressant drugs on responsiveness to pain

scientific article published in January 1991

Role of noradrenergic system in the mechanism of action of endogenous neurotoxin 1,2,3,4-tetrahydroisoquinoline: biochemical and functional studies.

scientific article published in January 2002

Salsolinol, 3-O-methyl-dopa and homovanillic acid in the cerebrospinal fluid of Parkinson patients

scientific article published on 01 September 1997

Salsolinol, an endogenous compound triggers a two-phase opposing action in the central nervous system

scientific article

Search for new antiarrhythmic and hypotensive compounds. Synthesis, antiarrhythmic, antihypertensive, and alpha-adrenoceptor blocking activity of novel 1-[(2-hydroxy-3-amino)]-propylpyrrolidin-2-one derivatives

scientific article published on 01 July 1997

Serotonin, dopamine, noradrenaline and their metabolites: levels in the brain of the house cricket (Acheta domesticus L.) during a 24-hour period and after administration of quipazine--a 5-HT2 receptor agonist

scientific article

Stability and variability of locomotor responses of laboratory rodents. I. Native exploratory and basal locomotor activity of Albino-Swiss mice

scientific article published in May 1987

Stability and variability of locomotor responses of laboratory rodents. II. Native exploratory and basal locomotor activity of Wistar rats

scientific article published in May 1987

Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats

scientific article

Synthesis and anticonvulsant activity of 1,2-aminoalkanol derivatives

scientific article published on 01 November 1998

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 1. Synthesis and pharmacological activity of chain derivatives of 1-aryl-2-iminoimidazolidine containing urea moiety.

scientific article published in October 2001

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 3. Synthesis and pharmacological activity of 1-aryl-5,6(1H)dioxo-2,3-dihydroimidazo[1,2-a]imidazoles

scientific article

Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine: part 2. Synthesis and pharmacological activity of 1,6-diaryl-5,7(1H)dioxo-2,3-dihydroimidazo[1,2-a][1,3,5]triazines.

scientific article published in September 2002

Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activity.

scientific article published in March 2002

Synthesis, physicochemical properties, anticonvulsant activities and voltage-sensitive calcium channels affinity of N-substituted amides of alpha-(4-phenylpiperazino)-GABA. Part 3: Search for new anticonvulsant compounds

scientific article published in April 1999

Synthesis, physicochemical properties, anticonvulsant activities, and GABA-ergic and voltage-sensitive calcium channel receptor affinities of alpha-substituted N-benzylamides of gamma-hydroxybutyric acid. Part 4: Search for new anticonvulsant compou

scientific article

The Ca2+ channel blockade changes the behavioral and biochemical effects of immobilization stress

scientific article published in March 1999

The Effect of Chronic Mild Stress and Imipramine on the Markers of Oxidative Stress and Antioxidant System in Rat Liver

scientific article published on 10 March 2016

The Protective Effect of Repeated 1MeTIQ Administration on the Lactacystin-Induced Impairment of Dopamine Release and Decline in TH Level in the Rat Brain

scholarly article by Agnieszka Wąsik et al published October 2018 in Neurotoxicity Research

The adenosinergic system is involved in sensitization to morphine withdrawal signs in rats-neurochemical and molecular basis in dopaminergic system

scientific article published on 18 April 2016

The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells.

scientific article published on 6 October 2007

The effect of an endogenous compound 1-methyl-1,2,3,4,-tetrahydroisoquinoline on morphine-induced analgesia, dependence and neurochemical changes in dopamine metabolism in rat brain structures

scientific article

The effect of calcium channel blockade during electroconvulsive treatment on cerebral cortical adrenoceptor subpopulations in the rat.

scientific article published in March 1993

The effect of chronic imipramine and electroconvulsive shock treatment on [3H]DADLE binding to cortical membranes of rats pretreated with chronic reserpine or 6-hydroxydopamine

scientific article published on February 1987

The effect of morphine dependence and abstinence on opioid receptors in the cerebral cortex and spinal cord of the rat.

scientific article

The effect of multiple imipramine administration on monoaminergic systems of the rat brain

scientific article published on 01 July 1980

The effect of neuroleptics of serotonergic system of the rat brain

scientific article published in March 1978

The impact of 1MeTIQ on the dopaminergic system function in the 6-OHDA model of Parkinson's disease

scientific article published on 13 August 2016

The influence of acute and chronic administration of 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline on the function of the nigrostriatal dopaminergic system in rats

scientific article

The influence of chronic treatment with antidepressant neuroleptics on the central serotonin system

scientific article

The influence of naloxone on the effects of adenosine receptor agonists in analgesic tests and binding studies.

scientific article published in January 1994

The lack of effect of chronic administration of imipramine and electroconvulsive shock on opioid mu, delta and kappa receptors in the spinal cord

scientific article

The mechanism of 1,2,3,4-tetrahydroisoquinolines neuroprotection: the importance of free radicals scavenging properties and inhibition of glutamate-induced excitotoxicity

scientific article

The mechanism of neuroprotective action of natural compounds

scientific article published on 30 April 2017

The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA.

scientific article published on 5 November 2016

Voltage-operated calcium channels: characteristics and their role in the mechanism of action of psychotropic drugs

scientific article

Withdrawal from repeated administration of a low dose of reserpine induced opposing adaptive changes in the noradrenaline and serotonin system function: a behavioral and neurochemical ex vivo and in vivo studies in the rat.

scientific article