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List of works by Micheline Piquette-Miller

99mTc-Sestamibi, a sensitive probe for in vivo imaging of P-glycoprotein inhibition by modulators and mdr1 antisense oligodeoxynucleotides.

scientific article published on November 2006

An injectable depot system for sustained intraperitoneal chemotherapy of ovarian cancer results in favorable drug distribution at the whole body, peritoneal and intratumoral levels.

scientific article

Animal models of acute moderate hypoxia are associated with a down-regulation of CYP1A1, 1A2, 2B4, 2C5, and 2C16 and up-regulation of CYP3A6 and P-glycoprotein in liver

scientific article published on 15 February 2007

Aprepitant and fosaprepitant drug interactions: a systematic review.

scientific article published on 4 May 2017

BRCA Status Does Not Predict Synergism of a Carboplatin and Olaparib Combination in High-Grade Serous Ovarian Cancer Cell Lines

scientific article published on 01 June 2018

Battling the HIV/AIDS Epidemic: Triumphs and Barriers

article

Blood-brain barrier: an impediment to neuropharmaceuticals

scientific article published on 24 February 2015

Breast cancer resistance protein (BCRP)-mediated glyburide transport: effect of the C421A/Q141K BCRP single-nucleotide polymorphism.

scientific article

Cellular Uptake and Metabolism of DNA Frayed Wires ⬇️

scientific article published on October 7, 2003

Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures.

scientific article published on May 2004

Characterization of guanidine transport in human renal brush border membranes

scientific article published on July 1, 1997

Chemotherapy dosing schedule influences drug resistance development in ovarian cancer.

scientific article published on 6 May 2011

Chitosan-phospholipid blend for sustained and localized delivery of docetaxel to the peritoneal cavity

scientific article published on 12 May 2009

Clinical Drug-Drug Interaction Evaluations to Inform Drug Use and Enable Drug Access.

scientific article published on 20 April 2017

Combination Drug Delivery Strategy for the Treatment of Multidrug Resistant Ovarian Cancer ⬇️

scientific article published on December 17, 2010

Continuous docetaxel chemotherapy improves therapeutic efficacy in murine models of ovarian cancer

scientific article

Continuous intraperitoneal carboplatin delivery for the treatment of late-stage ovarian cancer.

scientific article published on 21 August 2013

Cytokines Alter the Expression and Activity of the Multidrug Resistance Transporters in Human Hepatoma Cell Lines; Analysis Using RT‐PCR and cDNA Microarrays ⬇️

scientific article published on November 1, 2003

Decreased expression and activity of P-glycoprotein in rat liver during acute inflammation.

scientific article published in May 1998

Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.

scientific article

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

scientific article published on 12 July 2018

Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin.

scientific article

Drug release mechanism of paclitaxel from a chitosan-lipid implant system: effect of swelling, degradation and morphology.

scientific article published on 17 November 2007

Dysregulation of solute carrier transporters in malaria-infected pregnant mice

scientific article published on 20 February 2019

Effect of Chronic Kidney Disease on Nonrenal Elimination Pathways: A Systematic Assessment of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and OATP.

scientific article published on 9 October 2017

Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition

scientific article published on 23 January 2015

Effect of adjuvant arthritis on the disposition of acebutolol enantiomers in rats

scientific article published on 01 November 1992

Effect of aging on the pharmacokinetics of acebutolol enantiomers.

scientific article published in February 1992

Effect of endotoxin on the expression of placental drug transporters and glyburide disposition in pregnant rats

scientific journal article

Effects of sustained and intermittent paclitaxel therapy on tumor repopulation in ovarian cancer.

scientific article

Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging

scientific article

Endotoxin Modulates the Expression of Renal Drug Transporters in HIV-1 Transgenic Rats

scientific article published on 01 January 2018

Endotoxin-Mediated Downregulation of Hepatic Drug Transporters in HIV-1 Transgenic Rats.

scientific article published on 14 March 2016

Epigenetics: a new link toward understanding human disease and drug response

scientific article published on 01 December 2012

Ethnic differences in drug metabolism and toxicity from chemotherapy

article

Expression of ABC Efflux transporters in placenta from women with insulin-managed diabetes

scientific article

Functional and molecular characteristics of Na(+)-dependent nucleoside transporters.

scientific article published in November 1997

Gestational and pregnane X receptor-mediated regulation of placental ATP-binding cassette drug transporters in mice.

scientific article published on 2 December 2010

Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis.

scientific article published on 16 April 2007

High-performance liquid chromatographic determination of diacetolol enantiomers

scientific article published on 01 November 1990

Impact of endotoxin on the expression of drug transporters in the placenta of HIV-1 transgenic (HIV-Tg) rats.

scientific article

Impact of endotoxin-induced changes in P-glycoprotein expression on disposition of doxorubicin in mice.

scientific article

Impact of intraperitoneal, sustained delivery of paclitaxel on the expression of P-glycoprotein in ovarian tumors.

scientific article published on 7 October 2006

Impact of polyinosinic/polycytidylic acid on placental and hepatobiliary drug transporters in pregnant rats.

scientific article

In vitro and in vivo characterization of a novel biocompatible polymer-lipid implant system for the sustained delivery of paclitaxel.

scientific article

In vivo disposition and stability of DNA frayed wires in mice.

scientific article published on 12 May 2006

Inflammation: extinguishing the fires within.

scientific article

Inflammation: the dynamic force of health and disease

scientific article published on 01 October 2014

Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

scientific article published in October 2002

Involvement of Nuclear Factor κB, not Pregnane X Receptor, in Inflammation-Mediated Regulation of Hepatic Transporters.

scientific article

Malaria infection alters the expression of hepatobiliary and placental drug transporters in pregnant mice

scientific article published on 26 November 2013

Maternal bacterial infections impact expression of drug transporters in human placenta.

scientific article published on 21 April 2015

Mechanisms of reduced maternal and fetal lopinavir exposure in a rat model of gestational diabetes.

scientific article

Network medicine: finding the links to personalized therapy.

scientific article

Neurobiological Mechanisms of Chemotherapy-induced Cognitive Impairment in a Transgenic Model of Breast Cancer

scientific article published on 4 November 2017

Novel biocompatible intraperitoneal drug delivery system increases tolerability and therapeutic efficacy of paclitaxel in a human ovarian cancer xenograft model.

scientific article published on 21 March 2007

Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties.

scientific article published on 25 April 2006

Optimizing cancer care: is the future bright?

scientific article published in September 2011

Pharmacogenetics of pharmacoecology: which route to personalized medicine?

scientific article published in April 2009

Pharmacokinetic studies in pregnant women.

scientific article

Pharmacokinetics and multiple peaking of acebutolol enantiomers in rats ⬇️

scientific article published on August 1, 1997

Pharmacokinetics of acebutolol enantiomers in humans

scientific article published on 01 April 1991

Poly(I:C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation

scientific article published on 15 April 2019

Polyinosinic/Polycytidylic Acid-mediated changes in maternal and fetal disposition of lopinavir in rats

scientific article published on 17 April 2015

Ratio-Dependent Synergism of a Doxorubicin and Olaparib Combination in 2D and Spheroid Models of Ovarian Cancer

scientific article published on 28 December 2017

Recent advances in drug delivery strategies for treatment of ovarian cancer ⬇️

scientific article published on March 27, 2012

Regulation of drug transporters during infection and inflammation.

scientific article published on April 2007

Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer

scientific article published on 01 February 2008

Regulation of multidrug resistance by pro-inflammatory cytokines.

scientific article published on June 2006

Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice.

scientific article

Regulation of transporters by nuclear hormone receptors: implications during inflammation.

scientific article published on 12 December 2007

Response to 'Aprepitant and fosaprepitant decrease the effectiveness of hormonal contraceptives'.

scientific article published on 6 January 2018

SLC Neurotransmitter Transporters as Therapeutic Targets for Alcohol Use Disorder: A Narrative Review

scientific article published on 30 August 2020

Selective effect of adjuvant arthritis on the disposition of propranolol enantiomers in rats detected using a stereospecific HPLC assay

scientific article published on 01 February 1993

Synthesis and physicochemical and dynamic mechanical properties of a water-soluble chitosan derivative as a biomaterial

scientific article published on 01 October 2006

Synthesis and physicochemical and dynamic mechanical properties of a water-soluble chitosan derivative as a biomaterial

scientific article published on 01 December 2006

The Bugs Within Our Body: The Human Microbiota

scientific article published in June 2016

The Role of PXR Genotype and Transporter Expression in the Placental Transport of Lopinavir in Mice

scientific article published on 24 October 2017

The art and science of personalized medicine

scientific article published on 01 March 2007

The effects of lipiodol and cyclosporin A on the hepatobiliary disposition of doxorubicin in pigs

scientific article published on 07 March 2014

The impact of sustained and intermittent docetaxel chemotherapy regimens on cognition and neural morphology in healthy mice

scientific article published on 8 October 2013

The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and -metabolizing enzymes in mice.

scientific article published on 28 December 2005

Translational pharmacology: harnessing increased specialization of research within the basic biological sciences

scientific article published on 01 June 2008

Transport of glyburide by placental ABC transporters: implications in fetal drug exposure.

scientific article

User considerations in assessing pharmacogenomic tests and their clinical support tools

scientific article published on 11 September 2018

Within Our Skin

scientific article published on 01 July 2017

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