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List of works by Angeles Almeida

A novel human Cdh1 mutation impairs anaphase promoting complex/cyclosome activity resulting in microcephaly, psychomotor retardation, and epilepsy

scientific article published on 22 August 2019

A rapid method for the isolation of metabolically active mitochondria from rat neurons and astrocytes in primary culture ⬇️

scientific article published on March 1, 1998

A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

scientific article published in April 2001

APC/C-Cdh1 coordinates neurogenesis and cortical size during development

scientific article published on January 2013

APC/CCdh1-Rock2 pathway controls dendritic integrity and memory

scientific article

Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization

scientific article published on 16 November 2018

Antioxidant and bioenergetic coupling between neurons and astrocytes.

scientific article published on April 2012

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.

scientific article

Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.

scientific article published on 10 October 2009

Brain energy metabolism in glutamate-receptor activation and excitotoxicity: role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway.

scientific article published on 12 February 2013

Cdh1/Hct1-APC is essential for the survival of postmitotic neurons.

scientific article published on September 2005

Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

scientific journal article

Cdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons.

scientific article

Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes.

scientific article published on 31 October 2016

D-Glucose prevents glutathione oxidation and mitochondrial damage after glutamate receptor stimulation in rat cortical primary neurons

scientific article published on 01 October 2000

DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1.

scientific article

E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

scientific article

Effect of ethanol consumption on adult rat liver mitochondrial populations analyzed by flow cytometry

scientific article published on 01 October 1995

Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration

scientific article

Expression of glucose transporter GLUT3 by endotoxin in cultured rat astrocytes: the role of nitric oxide.

scientific article

Genetic determinants of neuronal vulnerability to apoptosis.

scientific article published on 14 June 2012

Glutamate excitoxicity is the key molecular mechanism which is influenced by body temperature during the acute phase of brain stroke

scientific article

Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion.

scientific article published in April 1998

Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

scientific article published on 07 August 2018

Hypothyroidism prevents postnatal changes in rat liver mitochondrial populations defined by rhodamine-123 staining

scientific article published on 01 October 1995

Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation.

scientific article published in January 2005

Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway

scientific journal article

Inhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5'-AMP-activated protein kinase

scientific journal article

Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system.

scientific article published on July 1997

Isolation and characterization of tightly coupled mitochondria from neurons and astrocytes in primary culture.

scientific article published in August 1997

Ketogenesis from lactate in rat liver during the perinatal period

scientific article published on 01 April 1992

Linking glycolysis with oxidative stress in neural cells: a regulatory role for nitric oxide.

scientific article published on November 2007

Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications.

scientific article published on 27 August 2009

Mitochondrial Complex I Activity is Conditioned by Supercomplex I-III2-IV Assembly in Brain Cells: Relevance for Parkinson's Disease.

scientific article

Mitochondrial respiratory chain and free radical generation in stroke.

scientific article

Modulation of astroglial energy metabolism by nitric oxide.

scientific article published on May 2006

Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism

scientific article published on 21 October 2016

Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.

scientific article published on 27 November 2007

Nitric oxide mediates brain mitochondrial damage during perinatal anoxia.

scientific article published in March 1998

Nitric oxide mediates brain mitochondrial maturation immediately after birth.

scientific article

Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

scientific article

Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke

scientific article published on 07 October 2020

PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1.

scientific article published on 24 July 2014

Peroxynitrite anion stimulates arginine release from cultured rat astrocytes

scientific article published on 01 October 1999

Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection

scientific journal article

Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress

scientific journal article

Postnatal changes in rhodamine-123 stained mitochondrial populations are sensitive to protein synthesis inhibitors but mimicked in vitro by ATP

scientific article published on 01 May 1994

Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria

scientific article published on 01 January 1994

Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain

scientific article published on 01 January 1995

Provoking neuroprotection by peroxynitrite.

scientific article published on January 2004

Regulation of APC/C-Cdh1 and Its Function in Neuronal Survival ⬇️

scientific article published on July 27, 2012

Regulation of Bcl-xL-ATP Synthase Interaction by Mitochondrial Cyclin B1-Cyclin-Dependent Kinase-1 Determines Neuronal Survival

scientific article

Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia

scientific article

Retinoic acid downregulates Rae1 leading to APC(Cdh1) activation and neuroblastoma SH-SY5Y differentiation

scientific article published on 21 January 2008

Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice

scientific article published on 12 August 2019

The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia.

scientific article

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

scientific article published on 17 May 2009

The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke. ⬇️

scientific article

The pentose-phosphate pathway in neuronal survival against nitrosative stress.

scientific article published on January 2010

Thyroid hormones regulate the onset of osmotic activity of rat liver mitochondria after birth

scientific article published on 01 February 1997

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