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List of works by Yoko Hirata

(Arylthio)cyclopentenones derivatives prevent glutamate-induced HT22 cell death through a PPAR gamma-dependent pathway.

scientific article

A Comparative Analysis of the Molecular Features of MANF and CDNF

scientific article published on 28 January 2016

A highly sensitive assay of IRE1 activity using the small luciferase NanoLuc: Evaluation of ALS-related genetic and pathological factors.

scientific article published on 06 June 2015

A rapid assay for glial cell line-derived neurotrophic factor and neurturin based on transfection of cells with tyrosine hydroxylase promoter-luciferase construct.

scientific article published on May 2003

A sensitive assay for the biosynthesis and secretion of MANF using NanoLuc activity.

scientific article

Acidification of the Golgi apparatus is indispensable for maturation but not for cell surface delivery of Ret.

scientific article

Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.

scientific article published in January 2005

Allele distribution and effect on reporter gene expression of vasopressin receptor gene (AVPR1a)-linked VNTR in primates

scientific article

Anti-apoptotic and pro-apoptotic effect of NEPP11 on manganese-induced apoptosis and JNK pathway activation in PC12 cells.

scientific article published in September 2004

Application of NanoBiT for Monitoring Dimerization of the Null Hong Kong Variant of α-1-Antitrypsin, NHK, in Living Cells

scientific article published on 01 August 2018

Application of NanoLuc to monitor the intrinsic promoter activity of GRP78 using the CRISPR/Cas9 system

scientific article published on 12 August 2016

Application of a novel HiBiT peptide tag for monitoring ATF4 protein expression in Neuro2a cells.

scientific article published on 15 August 2017

Azepine derivative T4FAT, a new copper chelator, inhibits tyrosinase

scientific article published on 19 December 2018

Biosynthesis, processing, and secretion of glial cell line-derived neurotrophic factor in astroglial cells.

scientific article

Characterization of 3'-untranslated region of the mouse GDNF gene ⬇️

scientific article published on January 17, 2012

Characterization of IRE1α in Neuro2a cells by pharmacological and CRISPR/Cas9 approaches

scientific article published on 13 December 2019

Characterization of V-ATPase inhibitor-induced secretion of cysteine-rich with EGF-like domains 2.

scientific article published on April 2014

Characterization of the 5'-flanking region of the mouse asparagine-linked glycosylation 12 homolog gene.

scientific article published on July 2013

Characterization of the Role of MANF in Regulating the Secretion of CRELD2.

scientific article published on January 2015

Characterization of the expression and cell-surface localization of transmembrane protein 132A.

scientific article published on 22 July 2012

Chloroquine inhibits glutamate‐induced death of a neuronal cell line by reducing reactive oxygen species through sigma‐1 receptor ⬇️

scientific article published on October 3, 2011

Degradation of caspase-activated DNase by the ubiquitin-proteasome system.

scientific article published on 15 December 2007

Determination of hypoxic effect on neprilysin activity in human neuroblastoma SH-SY5Y cells using a novel HPLC method

scientific article published on August 2005

Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis.

scientific article published in October 2006

Differential regulation of the transcriptional activity of the orphan nuclear receptor NGFI-B by membrane depolarization and nerve growth factor

scientific article published on 01 December 1997

Distribution ofRGS4mRNA in Mouse Brain Shown byin SituHybridization ⬇️

scientific article published on December 18, 1997

Effects of 2-(2-Chlorophenyl)ethylbiguanide on ERAD Component Expression in HT-29 Cells Under a Serum- and Glucose-Deprived Condition

scientific article published on 16 February 2019

Effects of stress on release of dopamine and serotonin in the striatum of spontaneously hypertensive rats: an in vivo voltammetric study

scientific article published on 01 January 1984

Effects of thyrotropin releasing hormone and its analogue, DN 1417, on biopterin concentration and tryptophan hydroxylation in rat raphe slices.

scientific article published on December 1987

Elucidating post-translational regulation of mouse CREB3 in Neuro2a cells.

scientific article published on 17 February 2018

Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells.

scientific article published on 8 July 2016

Elucidation of the Molecular Characteristics of Wild-Type and ALS-Linked Mutant SOD1 Using the NanoLuc Complementation Reporter System

scientific article published on 17 August 2019

Expression analysis and functional characterization of the mouse cysteine-rich with EGF-like domains 2

scientific article published in Scientific Reports

Functional validation of ATF4 and GADD34 in Neuro2a cells by CRISPR/Cas9-mediated genome editing.

scientific article

GRP78-binding protein regulates cAMP-induced glial fibrillary acidic protein expression in rat C6 glioblastoma cells.

scientific article published on 21 June 2006

Glial cell line-derived neurotrophic factor up-regulates the expression of tyrosine hydroxylase gene in human neuroblastoma cell lines

scientific article

Hormetic Effects of Binaphthyl Phosphonothioates as Pro-oxidants and Antioxidants

scientific article published on 29 October 2020

Identification of a novel GDNF mRNA induced by LPS in immune cell lines.

scientific article

Inhibition of double-stranded RNA-dependent protein kinase prevents oxytosis and ferroptosis in mouse hippocampal HT22 cells

scientific article published on 25 February 2019

Inhibition of monoamine oxidase by N-methylisoquinolinium ion

scientific article published on 01 March 1987

Inhibition of tyrosine hydroxylation in tissue slices of the rat striatum by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

scientific article published in June 1985

Intracellular trafficking and secretion of mouse mesencephalic astrocyte-derived neurotrophic factor.

scientific article

Knockdown of transmembrane protein 132A by RNA interference facilitates serum starvation-induced cell death in Neuro2a cells.

scientific article published on 09 May 2010

Localization of cyclooxygenase-2 induced following traumatic spinal cord injury

scientific article published on 01 January 2005

Manganese regulates caspase-3 gene promoter activity by inducing Sp1 phosphorylation in PC12 cells.

scientific article

Manganese-induced apoptosis in PC12 cells.

scientific article

Mitogenic effect of glial cell line-derived neurotrophic factor is dependent on the activation of p70S6 kinase, but independent of the activation of ERK and up-regulation of Ret in SH-SY5Y cells

scientific article published in September 2003

N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor

scientific article published on May 2004

N-methylisoquinolinium ion as an inhibitor of tyrosine hydroxylase, aromatic l-amino acid decarboxylase and monoamine oxidase.

scientific article

Neuroprotective cyclopentenone prostaglandins up-regulate neurotrophic factors in C6 glioma cells.

scientific article

Neuroprotective effects of Brazilian green propolis on oxytosis/ferroptosis in mouse hippocampal HT22 cells

scientific article published on 10 July 2019

Novel Oxindole-Curcumin Hybrid Compound for Antioxidative Stress and Neuroprotection

scientific article published on 18 December 2019

Novel oxindole derivatives prevent oxidative stress-induced cell death in mouse hippocampal HT22 cells.

scientific article published on 15 March 2018

Oxidation of N-methyl-1,2,3,4-tetrahydroisoquinoline into the N-methyl-isoquinolinium ion by monoamine oxidase

scientific article published on 01 February 1989

Phosphorylation and activation of p70 S6 kinase by manganese in PC12 cells

scientific article published on 01 September 1998

Prevention of oxytosis-induced c-Raf down-regulation by (arylthio)cyclopentenone prostaglandins is neuroprotective.

scientific article

RNAi knockdown of caspase-activated DNase inhibits rotenone-induced DNA fragmentation in HeLa cells.

scientific article published on 18 January 2007

Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins.

scientific article published on 7 June 2007

Reduced Sulfation Enhanced Oxytosis and Ferroptosis in Mouse Hippocampal HT22 Cells

scientific article published on 06 January 2020

Regulation of the ER-bound transcription factor Luman/CREB3 in HEK293 cells

scientific article published on 21 July 2019

Rehmannia glutinosa induces glial cell line-derived neurotrophic factor gene expression in astroglial cells via cPKC and ERK1/2 pathways independently.

scientific article published on 4 April 2006

Role of an ER stress response element in regulating the bidirectional promoter of the mouse CRELD2 - ALG12 gene pair.

scientific article

Rotenone and CCCP inhibit tyrosine hydroxylation in rat striatal tissue slices.

scientific article

Royal jelly reduces depression-like behavior through possible effects on adrenal steroidogenesis in a murine model of unpredictable chronic mild stress

scientific article published on 20 November 2019

SOD1 dimerization monitoring using a novel split NanoLuc, NanoBit

scientific article published on 29 September 2016

Studies on the uptake of N-methylisoquinolinium ion into rat striatal slices using high-performance liquid chromatography with fluorimetric detection

scientific article published on 01 March 1990

Studies on tyrosine hydroxylase system in rat brain slices using high-performance liquid chromatography with electrochemical detection

scientific article published on 01 June 1983

Synthesis of 3-Arylmethyl-2-oxindole Derivatives and Their Effects on Neuronal Cell Death.

scientific article published in January 2017

Synthesis of 3-[4-(dimethylamino)phenyl]alkyl-2-oxindole derivatives and their effects on neuronal cell death.

scientific article

Synthesis of neuroprotective cyclopentenone prostaglandin analogs: suppression of manganese-induced apoptosis of PC12 cells

scientific article published on 15 December 2006

The role of dopamine transporter in selective toxicity of manganese and rotenone.

scientific article

Transcriptional and post-transcriptional regulation of transmembrane protein 132A.

scientific article published on 30 April 2015

Transcriptional and post-translational regulation of mouse cation transport regulator homolog 1.

scientific article published on 25 April 2013

Transcriptional regulation of mouse mesencephalic astrocyte-derived neurotrophic factor in Neuro2a cells.

scientific article published on 17 July 2013

Translational and post-translational regulation of mouse cation transport regulator homolog 1

scientific article published on 15 June 2016

Tyrosine hydroxylase activity in caudate nucleus from Parkinson's disease: effects of iron and phosphorylating agents.

scientific article

Tyrosine hydroxylase and tryptophan hydroxylase activities and its cofactor biopterin level in brain regions of the rolling mouse: The influence of thyrotropin releasing hormone.

scientific article published in January 1982

Tyrosine hydroxylase, tryptophan hydroxylase, biopterin, and neopterin in the brains of normal controls and patients with senile dementia of Alzheimer type

scientific article

p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.

scientific article published on 19 June 2006

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