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List of works by Daniel D Bikle

1α,25(OH)2-Dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway ⬇️

scientific article published on September 28, 2012

A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting

scientific article published on 8 August 2015

Ablation of Ephrin B2 in Col2 Expressing Cells Delays Fracture Repair

scientific article published on 28 September 2020

Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair

scientific article

Ablation of the Calcium-Sensing Receptor in Keratinocytes Impairs Epidermal Differentiation and Barrier Function ⬇️

scientific article published on May 24, 2012

Anabolic effects of IGF-1 signaling on the skeleton ⬇️

scientific article published on 04 February 2013

Anticancer activity of VDR-coregulator inhibitor PS121912.

scientific article

Antitumor Activity of 3-Indolylmethanamines 31B and PS121912.

scientific article

Autocrine and Paracrine Actions of IGF-I Signaling in Skeletal Development

scientific article published on 25 September 2013

Calcium regulation of keratinocyte differentiation ⬇️

scientific article published on July 1, 2012

Calcium, Orai1, and epidermal proliferation

scientific article published on June 2014

Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1

scientific article

Claude D Arnaud, Jr, MD (1929-2016): ASBMR Loses a Founding Father

scientific article published on 27 August 2016

Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations ⬇️

scientific article published on December 22, 2011

Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-epithelialization

scientific article published on 22 March 2017

Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration

scientific article published on 28 August 2020

Development and progression of alopecia in the vitamin D receptor null mouse

scientific article published on May 2006

Development of novel Vitamin D Receptor-Coactivator Inhibitors

scientific article published on February 2014

Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators

scientific article published on 16 May 2012

Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer

scientific article

Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice

scientific article published on November 2010

Do sunscreens block vitamin D production? A critical review by an international panel of experts

scientific article published on 01 July 2019

Editorial: Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions

scientific article published on 11 February 2020

Ephrin B2/EphB4 mediates the actions of IGF-I signaling in regulating endochondral bone formation

scientific article published on August 2014

Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation

scientific article

Evaluation of fetal bone structure and mineralization in IGF-I deficient mice using synchrotron radiation microtomography and Fourier transform infrared spectroscopy.

scientific article published on 14 August 2006

Expression and functional assessment of an alternatively spliced extracellular Ca2+-sensing receptor in growth plate chondrocytes

scientific article published on 15 September 2005

Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-I.

scientific article published in May 2006

Gender-Specific Differences in the Skeletal Response to Continuous PTH in Mice Lacking the IGF1 Receptor in Mature Osteoblasts

scientific article

Hairless suppresses vitamin D receptor transactivation in human keratinocytes

scientific article

Highlights from the 17th workshop on vitamin D, Chicago, IL, June 17-21, 2014.

scientific article

Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3.

scientific article

Hypercalcemia and overexpression of CYP27B1 in a patient with nephrogenic systemic fibrosis: clinical vignette and literature review.

scientific article published on June 2009

IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENING

scientific article published on January 2014

IGF-I Signaling in Osterix-Expressing Cells Regulates Secondary Ossification Center Formation, Growth Plate Maturation, and Metaphyseal Formation During Postnatal Bone Development

scientific article

IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone

scientific article published in September 2007

Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes

scientific article published on 7 December 2007

Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone

scientific article published in September 2002

Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading

scientific article

Insulin-like growth factor-I is essential for embryonic bone development

scientific article published on 20 July 2006

Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth

scientific article published in January 2002

LncRNA profiling reveals new mechanism for VDR protection against skin cancer formation

scientific article published on 14 December 2013

LncRNA: a new player in 1α, 25(OH)(2) vitamin D(3) /VDR protection against skin cancer formation

scientific article published on March 2014

Mammary-Specific Ablation of the Calcium-Sensing Receptor During Lactation Alters Maternal Calcium Metabolism, Milk Calcium Transport, and Neonatal Calcium Accrual ⬇️

scientific article published on June 19, 2013

Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene

scientific article

Myosin 1a Regulates Osteoblast Differentiation Independent of Intestinal Calcium Transport

scientific article published on 12 August 2019

Negative cross-talk between calcium-sensing receptor and β-catenin signaling systems in colonic epithelium

scientific article published on 17 November 2011

New aspects of vitamin D metabolism and action - addressing the skin as source and target

scientific article published on 06 February 2020

Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer

scientific article

Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing

scientific article published on 19 March 2015

Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice ⬇️

scientific article published on August 4, 2011

PTH differentially regulates expression of RANKL and OPG.

scientific article published on 16 December 2003

Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor

scientific article published on 10 June 2013

Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation

scientific article published on 21 January 2009

Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes

scientific article published in January 2005

Phosphoprotein Phosphatase 1 Is Required for Extracellular Calcium-Induced Keratinocyte Differentiation

scientific article published on 2 June 2016

Physiologic and pathophysiologic roles of extra renal CYP27b1: Case report and review.

scientific article published on 26 February 2018

Protective role of vitamin D signaling in skin cancer formation ⬇️

scientific article published on October 8, 2012

Quantification of the vitamin D receptor-coregulator interaction

scientific article

Rapid onset of hypercalcemia from high-grade lymphoma in the setting of HIV-related immune reconstitution inflammatory syndrome

article

Reciprocal role of vitamin D receptor on β-catenin regulated keratinocyte proliferation and differentiation

scientific article

Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway.

scientific article published on 10 February 2016

Role of IGF-I signaling in regulating osteoclastogenesis

scientific article published in September 2006

Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma

scientific article published in May 2003

SERCA2-Controlled Ca2+-Dependent Keratinocyte Adhesion and Differentiation Is Mediated via the Sphingolipid Pathway: A Therapeutic Target for Darier's Disease ⬇️

scientific article published on January 26, 2012

Selective Hyaluronan-CD44 Signaling Promotes miRNA-21 Expression and Interacts with Vitamin D Function during Cutaneous Squamous Cell Carcinomas Progression Following UV Irradiation

scientific article published on 13 May 2015

Sex and age modify biochemical and skeletal manifestations of chronic hyperparathyroidism by altering target organ responses to Ca2+ and parathyroid hormone in mice ⬇️

scientific article published on May 1, 2013

Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways

scientific article published on 22 December 2003

Squamous cell carcinomas fail to respond to the prodifferentiating actions of 1,25(OH)2D: why?

scientific article

Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites

scientific article published on 6 January 2016

The Calcium-Sensing Receptor-Dependent Regulation of Cell–Cell Adhesion and Keratinocyte Differentiation Requires Rho and Filamin A ⬇️

scientific article published on January 6, 2011

The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle.

scientific article

The effect of LXR activators on AP-1 proteins in keratinocytes

scientific article

The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes

scientific article published on 15 April 2002

The protective role of vitamin d signaling in non-melanoma skin cancer

scientific article

The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation.

scientific article published on 22 January 2007

The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes

scientific article published on 23 November 2006

The role of the calcium-sensing receptor in epidermal differentiation

scientific article published on March 2004

The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3.

scientific article published on November 2002

Transcriptional Regulation of Dental Epithelial Cell Fate

scientific article published on 25 November 2020

Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in VDR transactivation during keratinocyte differentiation.

scientific article

UVB induces epidermal 11β-hydroxysteroid dehydrogenase type 1 activity in vivo.

scientific article published in May 2015

VITAMIN D BINDING PROTEIN AND 25-HYDROXYVITAMIN D LEVELS: EMERGING CLINICAL APPLICATIONS.

scientific article published on 17 January 2017

Variability in free 25(OH) vitamin D levels in clinical populations

scientific article

Vitamin D Metabolism Revised: Fall of Dogmas

scientific article published on 29 October 2019

Vitamin D Prevents Sunburn: Tips for the Summer?

scientific article

Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair

scientific article published on 19 May 2018

Vitamin D and calcium regulation of epidermal wound healing

scientific article published on 14 August 2015

Vitamin D and skin cancer: a problem in gene regulation

scientific article

Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation

scientific article

Vitamin D receptor mediates DNA repair and is UV inducible in intact epidermis but not in cultured keratinocytes

scientific article published on 12 April 2012

Vitamin D3 Inhibits Hedgehog Signaling and Proliferation in Murine Basal Cell Carcinomas ⬇️

scientific article published on March 24, 2011

Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level

scientific article published on 08 February 2020

p120-Catenin Is Required for Dietary Calcium Suppression of Oral Carcinogenesis in Mice.

scientific article published on 28 September 2016

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