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List of works by Jiajun Zhao

A High Fat Diet Rich in Saturated and Mono-Unsaturated Fatty Acids Induces Disturbance of Thyroid Lipid Profile and Hypothyroxinemia in Male Rats.

scientific article published on 23 January 2018

A case of Klinefelter syndrome with aplastic anemia

scientific article published on 05 February 2011

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.

scientific article published on 12 June 2017

A novel mutation in TPRS1 gene caused tricho-rhino-phalangeal syndrome in a Chinese patient with severe osteoporosis

scientific article published on 01 May 2011

A novel role for thyroid-stimulating hormone: up-regulation of hepatic 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase expression through the cyclic adenosine monophosphate/protein kinase A/cyclic adenosine monophosphate-responsive element binding

scientific article published on 01 October 2010

A predictive model of thyroid malignancy using clinical, biochemical and sonographic parameters for patients in a multi-center setting.

scientific article published on 7 March 2018

AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver

scientific article published on May 2015

AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cells

scientific journal article

Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice.

scientific article

Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway.

scientific article

Analysis of the correlation between lipotoxicity and pituitary-thyroid axis hormone levels in men and male rats.

scientific article published on 14 June 2016

Appropriate insulin initiation dosage for insulin-naive type 2 diabetes outpatients receiving insulin monotherapy or in combination with metformin and/or pioglitazone

scientific article published on December 1, 2010

Association between Urinary Iodine Concentration and Thyroid Nodules in Adults: A Cross-Sectional Study in China

scientific article published on 17 December 2020

Association between different obesity phenotypes and hypothyroidism: a study based on a longitudinal health management cohort

scientific article published on 05 April 2021

Association between smoking and glycemic control in diabetic patients: Results from the Risk Evaluation of cAncers in Chinese diabeTic Individuals: A lONgitudinal (REACTION) study

scientific article published on 16 November 2017

Association between thyroid hormones and body fat in euthyroid subjects.

scientific article published on 23 September 2013

Association of TERT promoter mutation 1,295,228 C>T with BRAF V600E mutation, older patient age, and distant metastasis in anaplastic thyroid cancer

scientific article

Association of alcohol consumption with the impaired β-cell function independent of body mass index among Chinese men.

scientific article published on 15 March 2012

Association of maternal serum lipids at late gestation with the risk of neonatal macrosomia in women without diabetes mellitus.

scientific article

Benefits of Levothyroxine Replacement Therapy on Nonalcoholic Fatty Liver Disease in Subclinical Hypothyroidism Patients

scientific article

Characterization of a Relatively Malignant Form of Osteopetrosis Caused by a Novel Mutation in the PLEKHM1 Gene

scientific article published on 13 June 2016

Chronic ethanol consumption increases the levels of chemerin in the serum and adipose tissue of humans and rats

scientific article

Chronic ethanol consumption up-regulates protein-tyrosine phosphatase-1B (PTP1B) expression in rat skeletal muscle

scientific article published on November 22, 2010

Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium.

scientific article

Chronic leucine exposure results in reduced but reversible glucose-stimulated insulin secretion in INS-1 cells

scientific article published on 8 April 2014

Chronic palmitate exposure inhibits AMPKalpha and decreases glucose-stimulated insulin secretion from beta-cells: modulation by fenofibrate.

scientific article

Cilostazol protects diabetic rats from vascular inflammation via nuclear factor-kappa B-dependent down-regulation of vascular cell adhesion molecule-1 expression

scientific article published on 04 April 2006

Clinical and molecular characterization of 5α-reductase type 2 deficiency due to mutations (p.Q6X, p.R246Q) in SRD5A2 gene.

scientific article published on 10 April 2018

Cohort profile: risk evaluation of cancers in Chinese diabetic individuals: a longitudinal (REACTION) study

scientific article published on 09 January 2014

Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes

scientific article published on 15 August 2016

Consensus on the Prevention of Type 2 Diabetes in Chinese Adults

scientific article published on January 2017

Deletion of miRNAs in bone marrow prevents streptozotocin-induced murine autoimmune diabetes but deletion of miR-155 does not.

scientific article published on 25 March 2013

Dietary Lycium barbarum polysaccharide induces Nrf2/ARE pathway and ameliorates insulin resistance induced by high-fat via activation of PI3K/AKT signaling.

scientific article

Different Contributions of Dyslipidemia and Obesity to the Natural History of Type 2 Diabetes: 3-Year Cohort Study in China

article

Diosgenin induces apoptosis in IGF-1-stimulated human thyrocytes through two caspase-dependent pathways

scientific article published on 11 January 2012

Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease.

scientific article

Effects of chronic ethanol consumption on levels of adipokines in visceral adipose tissues and sera of rats.

scientific article

Effects of diosgenin on cell proliferation induced by IGF-1 in primary human thyrocytes

scientific article published on 01 June 2011

Effects of pioglitazone on high-fat-diet-induced ventricular remodeling and dysfunction in rats

scientific article published on 26 October 2011

Efficacy and safety of avandamet or uptitrated metformin treatment in patients with type 2 diabetes inadequately controlled with metformin alone: a multicenter, randomized, controlled trial

scientific article published on May 2015

Endoplasmic Reticulum Stress May Play a Pivotal Role in Lipid Metabolic Disorders in a Novel Mouse Model of Subclinical Hypothyroidism

scientific article published on 19 August 2016

Epidemiological characteristics of lower extremity arterial disease in Chinese diabetes patients at high risk: a prospective, multicenter, cross-sectional study.

scientific article

Ethanol feeding impairs insulin-stimulated glucose uptake in isolated rat skeletal muscle: role of Gs alpha and cAMP.

scientific article published in August 2005

Evaluation of a risk factor scoring model in screening for undiagnosed diabetes in China population.

scientific article

Even mildly elevated TSH is associated with an atherogenic lipid profile in postmenopausal women with subclinical hypothyroidism

scientific article published on 28 March 2014

Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification

scientific article published on 05 April 2022

Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes

scientific article published on 10 November 2017

Expression profiles of six circulating microRNAs critical to atherosclerosis in patients with subclinical hypothyroidism: a clinical study.

scientific article

Follicle-Stimulating Hormone Increases the Risk of Postmenopausal Osteoporosis by Stimulating Osteoclast Differentiation

scientific article published on 4 August 2015

Functional thyrotropin receptor expression in the ventricle and the effects on ventricular BNP secretion

scientific article published on 26 September 2013

Glycemic status and chronic kidney disease in Chinese adults: Findings from the REACTION study

scientific article published on 13 October 2016

High glucose induces the release of endothelin-1 through the inhibition of hydrogen sulfide production in HUVECs

scientific article

High-Cholesterol Diet Disrupts the Levels of Hormones Derived from Anterior Pituitary Basophilic Cells

scientific article

Hydrogen sulfide protects against high-glucose-induced apoptosis in endothelial cells

scientific article published on 01 February 2012

Identification and functional characterization of a large deletion of the CYP11B1 gene causing an 11β-Hydroxylase deficiency in a Chinese pedigree.

scientific article

Identification of two novel mutations in SLC12A3 gene in two Chinese pedigrees with Gitelman syndrome and review of literature.

scientific article

Increasing trend of diabetes combined with hypertension or hypercholesterolemia: NHANES data analysis 1999-2012

scientific article

Inhibitory effect of Kangjia Pill on thyrocyte proliferation in rat goiter model.

scientific article published on 18 August 2009

Initiating Characteristics of Early-onset Type 2 Diabetes Mellitus in Chinese Patients

scientific article published on January 2016

Insulin upregulates betatrophin expression via PI3K/Akt pathway

scientific article

Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-kappaB signaling pathway in FRTL thyroid cells.

scientific article

Integrative analysis of mRNA and miRNA array data reveals the suppression of retinoic acid pathway in regulatory T cells of Graves' disease.

scientific article

Intervention with cilostazol attenuates renal inflammation in streptozotocin-induced diabetic rats.

scientific article

Involvement of chronic stresses in rat islet and INS-1 cell glucotoxicity induced by intermittent high glucose.

scientific article published on 22 March 2008

Iodine Status and Prevalence of Thyroid Disorders After Introduction of Mandatory Universal Salt Iodization for 16 Years in China: A Cross-Sectional Study in 10 Cities.

scientific article

KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR GENES AND THEIR HLA-C LIGANDS IN HASHIMOTO THYROIDITIS IN A CHINESE POPULATION.

scientific article published on 4 April 2016

LDL in patients with subclinical hypothyroidism shows increased lipid peroxidation

scientific article

Lipid profiling reveals different therapeutic effects of metformin and glipizide in patients with type 2 diabetes and coronary artery disease.

scientific article published on 10 July 2014

Long-term ethanol exposure inhibits glucose transporter 4 expression via an AMPK-dependent pathway in adipocytes.

scientific article published on 22 February 2010

Long-term high animal protein diet reduces body weight gain and insulin secretion in diet-induced obese rats.

scientific article published on 11 April 2012

Long-term moderate ethanol consumption restores insulin sensitivity in high-fat-fed rats by increasing SLC2A4 (GLUT4) in the adipose tissue by AMP-activated protein kinase activation

scientific article

Mechanism of subclinical hypothyroidism accelerating endothelial dysfunction (Review)

scientific article

MiR-155 inhibits cell migration of human cardiomyocyte progenitor cells (hCMPCs) via targeting of MMP-16.

scientific article published on October 2012

MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1

scientific journal article

Multifactorial Intervention on Type 2 Diabetes (MIDiab) Study: A Multicenter, Open-Label, Randomized, Parallel Controlled, Community Trial

scientific article published on 01 July 2020

New perspectives of physiological and pathological functions of nucleolin (NCL).

scientific article

Nitric oxide synthase gene polymorphisms and nephropathy in Asians with Type 2 diabetes

scientific article published on 01 November 2006

Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?

scientific article published on 17 October 2018

Peroxisome proliferator-activated receptor α activation induces hepatic steatosis, suggesting an adverse effect

scientific article

Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate

scientific journal article

Phosphatidylinositol 3-kinase/nuclear factor-kappa B signaling pathway is involved in the regulation of IGF-I on Fas-associated death domain-like interleukin-1-converting enzyme-inhibitory protein expression in cultured FRTL thyroid cells

scientific article published on June 2007

Plasma glucose and hemoglobin A1c for the detection of diabetes in Chinese adults

scientific article published on 5 May 2015

Polymorphisms in the NLRP3 gene and risk of primary gouty arthritis.

scientific article published on 12 April 2013

Prevalence and control of diabetes in Chinese adults

scientific article published on September 2013

Reduced Kidney Function Is Associated With Cardiometabolic Risk Factors, Prevalent and Predicted Risk of Cardiovascular Disease in Chinese Adults: Results From the REACTION Study

scientific article published on 22 July 2016

Regression to normoglycaemia by fenofibrate in pre-diabetic subjects complicated with hypertriglyceridaemia: a prospective randomized controlled trial.

scientific article published on November 2010

Relative variations of gut microbiota in disordered cholesterol metabolism caused by high-cholesterol diet and host genetics.

scientific article

Role of exosome-associated microRNA in diagnostic and therapeutic applications to metabolic disorders

scientific article published in March 2018

Role of extrathyroidal TSHR expression in adipocyte differentiation and its association with obesity

scientific article published on 30 January 2012

SIMVASTATIN DECREASES SEX HORMONE LEVELS IN MALE RATS.

scientific article published on 16 November 2016

Subclinical hyperthyroidism and the risk of cardiovascular events and all-cause mortality: an updated meta-analysis of cohort studies.

scientific article

Suppression effects of AICAR on insulin secretion involved in peroxisome proliferator-activated receptor gamma changes in INS-1 cells.

scientific article

Swimming improves high-fat induced insulin resistance by regulating lipid and energy metabolism and the insulin pathway in rats

scientific article published on 9 April 2014

THYROID-STIMULATING HORMONE LEVELS ARE INVERSELY ASSOCIATED WITH SERUM TOTAL BILE ACID LEVELS: A CROSS-SECTIONAL STUDY.

scientific article published on 25 November 2015

The Prognostic Value of Tumor Multifocality in Clinical Outcomes of Papillary Thyroid Cancer

scientific article published on 05 June 2017

The correlation between serum free thyroxine and regression of dyslipidemia in adult males: A 4.5-year prospective study

scientific article published on September 2017

The effects of high-protein, low-carbohydrate diet on body weight and the expression of gastrointestinal hormones in diet-induced obesity rat

scientific article published on February 1, 2011

The frequency of daily ethanol consumption influences the effect of ethanol on insulin sensitivity in rats fed a high-fat diet.

scientific article published on 6 September 2011

The lipid-lowering effect of levothyroxine in patients with subclinical hypothyroidism: A systematic review and meta-analysis of randomized controlled trials

scientific article

The presence of adenosine A2a receptor in thyrocytes and its involvement in Graves' IgG-induced VEGF expression.

scientific article published on 30 September 2013

The regulation and function of the NUAK family.

scientific article published on 10 September 2013

The relationship between endogenous testosterone and lipid profile in middle-aged and elderly Chinese men.

scientific article published on 8 March 2014

The relationship between obesity indices and serum vitamin D levels in Chinese adults from urban settings

scientific article

Thyroid Stimulating Hormone Triggers Hepatic Mitochondrial Stress through Cyclophilin D Acetylation

scientific article published on 06 January 2020

Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.

scientific article published on 14 February 2017

Thyroid stimulating hormone, independent of thyroid hormone, can elevate the serum total cholesterol level in patients with coronary heart disease: a cross-sectional design

scientific article

Thyroid-stimulating hormone decreases HMG-CoA reductase phosphorylation via AMP-activated protein kinase in the liver.

scientific article published on 23 February 2015

Thyroid-stimulating hormone inhibits adipose triglyceride lipase in 3T3-L1 adipocytes through the PKA pathway

scientific article published on 15 January 2015

Thyroid-stimulating hormone maintains bone mass and strength by suppressing osteoclast differentiation.

scientific article published on 19 February 2014

Thyroid-stimulating hormone regulates hepatic bile acid homeostasis via SREBP-2/HNF-4α/CYP7A1 axis

scientific article published on 19 December 2014

Thyrotropin and obesity: increased adipose triglyceride content through glycerol-3-phosphate acyltransferase 3.

scientific article

Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity.

scientific article

Tissue-specific expression of PPAR mRNAs in diabetic rats and divergent effects of cilostazol.

scientific article published in July 2008

Urocortin ameliorates diabetic cardiomyopathy in rats via the Akt/GSK-3β signaling pathway

scientific article published on 23 January 2015

Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1.

scientific article published on January 2013