List of works - Luis Del Valle

'Signet-ring' cell gastric adenocarcinoma metastatic to a neurogenous hyperplasia of the appendix

scientific article published on 01 April 2007

A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.

scientific article published on 19 August 2016

Activation of PPARalpha inhibits IGF-I-mediated growth and survival responses in medulloblastoma cell lines.

scientific article

Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer

scientific article

Activation of the oxidative stress pathway by HIV-1 Vpr leads to induction of hypoxia-inducible factor 1alpha expression

scientific article

Angiocidin promotes pro-inflammatory cytokine production and antigen presentation in multiple sclerosis.

scientific article published on 22 January 2008

Angiostatic activity of obtustatin as alpha1beta1 integrin inhibitor in experimental melanoma growth.

scientific article

Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia ⬇️

scientific article published on August 28, 2012

Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses

scientific article published on 5 March 2015

BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy

scientific journal article

Bone marrow-derived mesenchymal stem cells undergo JCV T-antigen mediated transformation and generate tumors with neuroectodermal characteristics

scientific article

CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells

scientific article

CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells.

scientific article published on 12 December 2015

CD4+/CD56+ hematodermic neoplasm: presentation of 2 cases and review of the concept of an uncommon tumor originated in plasmacytoid dendritic cells expressing CD123 (IL-3 receptor alpha).

scientific article published on December 2007

Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression.

scientific article

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders

erratum published in September 2013

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders.

scientific article

Detection of JC virus DNA fragments but not proteins in normal brain tissue.

scientific article

Detection of JC virus DNA sequences and expression of viral T antigen and agnoprotein in esophageal carcinoma.

scientific article published in February 2005

Early growth response-1 protein is induced by JC virus infection and binds and regulates the JC virus promoter.

scientific article

Effects of JC virus infection on anti-apoptotic protein survivin in progressive multifocal leukoencephalopathy.

scientific article published on April 2007

Emmprin and KSHV: new partners in viral cancer pathogenesis.

scientific article published on 03 June 2013

Evidence for BAG3 modulation of HIV-1 gene transcription.

scientific article published on March 2007

GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1 ⬇️

scientific article published on January 15, 2002

Growth inhibition of glioblastoma cells by human Purα ⬇️

scientific article published on December 1, 2001

HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction

scientific article published in July 2011

HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.

scientific article published on 28 September 2011

HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.

scientific article published in September 2013

HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.

scientific article

Human polyomaviruses and brain tumors

Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy

scientific article

ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability

scientific article

IGF-IR-dependent expression of Survivin is required for T-antigen-mediated protection from apoptosis and proliferation of neural progenitors.

scientific article published on 16 October 2009

Immunohistochemical characterization of Renaut bodies in superficial digital nerves: further evidence supporting their perineurial cell origin.

scientific article

Importance of interaction between nerve growth factor and 9 1 integrin in glial tumor angiogenesis ⬇️

scientific article published on May 17, 2012

Inhibition of SNAP25 expression by HIV-1 Tat involves the activity of mir-128a

scientific article published on September 2008

Insulin-like growth factor I receptor signaling system in JC virus T antigen-induced primitive neuroectodermal tumors--medulloblastomas.

scientific article

Insulin‐like growth factor‐I–forkhead box O transcription factor 3a counteracts high glucose/tumor necrosis factor‐α‐mediated neuronal damage: Implications for human immunodeficiency virus encephalitis ⬇️

scientific article published on December 8, 2010

Interferon regulatory factor 4 is involved in Epstein-Barr virus-mediated transformation of human B lymphocytes

scientific article

JCPyV T-Antigen Activation of the Anti-Apoptotic Survivin Promoter-Its Role in the Development of Progressive Multifocal Leukoencephalopathy

scientific article published on 03 November 2020

Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin.

scientific article

Neuronal PINCH is regulated by TNF-α and is required for neurite extension.

scientific article published on 6 August 2010

Neurospheres and glial cell cultures: immunocytochemistry for cell phenotyping.

scientific article published on January 2013

Novel expression of PINCH in the central nervous system and its potential as a biomarker for human immunodeficiency virus-associated neurodegeneration.

scientific article published in August 2008

Novel polyomavirus associated with brain tumors in free-ranging raccoons, western United States

scientific article published on January 2013

PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA.

scientific article published on 18 July 2013

Potential mechanisms of the human polyomavirus JC in neural oncogenesis

scientific article published on August 2008

Potential role of gut microbiota, the proto-oncogene PIKE (Agap2) and cytochrome P450 CYP2W1 in promotion of liver cancer by alcoholic and nonalcoholic fatty liver disease and protection by dietary soy protein

scientific article published on 14 May 2020

Primary adamantinoma of the rib. Unusual presentation for a bone neoplasm of uncertain origin

scientific article published on 12 April 2008

ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro

scientific article published on 22 June 2010

Radiation-guided targeting of combretastatin encapsulated immunoliposomes to mammary tumors.

scientific article published on 27 January 2009

Re: Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories by Rollison et al. (published online 21 October 2004)

scientific article published on 01 November 2005

Regulatory effect of nerve growth factor in alpha9beta1 integrin-dependent progression of glioblastoma.

scientific article

Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer

scientific article

Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype.

scientific article published on 22 August 2016

Role for tumor necrosis factor-α in JC virus reactivation and progressive multifocal leukoencephalopathy

scientific article published on 24 December 2010

Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL)

scientific article

T-antigen of the human polyomavirus JC attenuates faithful DNA repair by forcing nuclear interaction between IRS-1 and Rad51

scientific article published on 01 January 2006

Targeted delivery of antibody conjugated liposomal drug carriers to rat myocardial infarction

scientific article

Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma

scientific article

Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.

scientific article

Temporal and geographic clustering of polyomavirus-associated olfactory tumors in 10 free-ranging raccoons (Procyon lotor).

scientific article

The homing receptor CD44 is involved in the progression of precancerous gastric lesions in patients infected with Helicobacter pylori and in development of mucous metaplasia in mice

scientific article

The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors

scientific article

Transcriptional regulation of HIV-1 gene expression by p53.

scientific article

Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network.

scientific article published on 14 January 2013

Tubulin-mediated binding of human immunodeficiency virus-1 Tat to the cytoskeleton causes proteasomal-dependent degradation of microtubule-associated protein 2 and neuronal damage.

scientific article published in April 2006

VEGF-related protein isolated fromVipera palestinaevenom, promotes angiogenesis

scientific article published on 01 April 2007

p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes.

scientific article published on December 2005

List of works by Luis Del Valle

'Signet-ring' cell gastric adenocarcinoma metastatic to a neurogenous hyperplasia of the appendix

A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.

Activation of PPARalpha inhibits IGF-I-mediated growth and survival responses in medulloblastoma cell lines.

Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer

Activation of the oxidative stress pathway by HIV-1 Vpr leads to induction of hypoxia-inducible factor 1alpha expression

Angiocidin promotes pro-inflammatory cytokine production and antigen presentation in multiple sclerosis.

Angiostatic activity of obtustatin as alpha1beta1 integrin inhibitor in experimental melanoma growth.

Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia ⬇️

Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses

BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy

Bone marrow-derived mesenchymal stem cells undergo JCV T-antigen mediated transformation and generate tumors with neuroectodermal characteristics

CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells

CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells.

CD4+/CD56+ hematodermic neoplasm: presentation of 2 cases and review of the concept of an uncommon tumor originated in plasmacytoid dendritic cells expressing CD123 (IL-3 receptor alpha).

Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression.

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders.

Detection of JC virus DNA fragments but not proteins in normal brain tissue.

Detection of JC virus DNA sequences and expression of viral T antigen and agnoprotein in esophageal carcinoma.

Early growth response-1 protein is induced by JC virus infection and binds and regulates the JC virus promoter.

Effects of JC virus infection on anti-apoptotic protein survivin in progressive multifocal leukoencephalopathy.

Emmprin and KSHV: new partners in viral cancer pathogenesis.

Evidence for BAG3 modulation of HIV-1 gene transcription.

GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1 ⬇️

Growth inhibition of glioblastoma cells by human Purα ⬇️

HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction

HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.

HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.

HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.

Human polyomaviruses and brain tumors

Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy

ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability

IGF-IR-dependent expression of Survivin is required for T-antigen-mediated protection from apoptosis and proliferation of neural progenitors.

Immunohistochemical characterization of Renaut bodies in superficial digital nerves: further evidence supporting their perineurial cell origin.

Importance of interaction between nerve growth factor and 9 1 integrin in glial tumor angiogenesis ⬇️

Inhibition of SNAP25 expression by HIV-1 Tat involves the activity of mir-128a

Insulin-like growth factor I receptor signaling system in JC virus T antigen-induced primitive neuroectodermal tumors--medulloblastomas.

Insulin‐like growth factor‐I–forkhead box O transcription factor 3a counteracts high glucose/tumor necrosis factor‐α‐mediated neuronal damage: Implications for human immunodeficiency virus encephalitis ⬇️

Interferon regulatory factor 4 is involved in Epstein-Barr virus-mediated transformation of human B lymphocytes

JCPyV T-Antigen Activation of the Anti-Apoptotic Survivin Promoter-Its Role in the Development of Progressive Multifocal Leukoencephalopathy

Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin.

Neuronal PINCH is regulated by TNF-α and is required for neurite extension.

Neurospheres and glial cell cultures: immunocytochemistry for cell phenotyping.

Novel expression of PINCH in the central nervous system and its potential as a biomarker for human immunodeficiency virus-associated neurodegeneration.

Novel polyomavirus associated with brain tumors in free-ranging raccoons, western United States

PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA.

Potential mechanisms of the human polyomavirus JC in neural oncogenesis

Potential role of gut microbiota, the proto-oncogene PIKE (Agap2) and cytochrome P450 CYP2W1 in promotion of liver cancer by alcoholic and nonalcoholic fatty liver disease and protection by dietary soy protein

Primary adamantinoma of the rib. Unusual presentation for a bone neoplasm of uncertain origin

ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro

Radiation-guided targeting of combretastatin encapsulated immunoliposomes to mammary tumors.

Re: Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories by Rollison et al. (published online 21 October 2004)

Regulatory effect of nerve growth factor in alpha9beta1 integrin-dependent progression of glioblastoma.

Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer

Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype.

Role for tumor necrosis factor-α in JC virus reactivation and progressive multifocal leukoencephalopathy

Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL)

T-antigen of the human polyomavirus JC attenuates faithful DNA repair by forcing nuclear interaction between IRS-1 and Rad51

Targeted delivery of antibody conjugated liposomal drug carriers to rat myocardial infarction

Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma

Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.

Temporal and geographic clustering of polyomavirus-associated olfactory tumors in 10 free-ranging raccoons (Procyon lotor).

The homing receptor CD44 is involved in the progression of precancerous gastric lesions in patients infected with Helicobacter pylori and in development of mucous metaplasia in mice

The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors

Transcriptional regulation of HIV-1 gene expression by p53.

Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network.

Tubulin-mediated binding of human immunodeficiency virus-1 Tat to the cytoskeleton causes proteasomal-dependent degradation of microtubule-associated protein 2 and neuronal damage.

VEGF-related protein isolated fromVipera palestinaevenom, promotes angiogenesis

p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes.