List of works - Hongchan An

Asymmetric Total Synthesis of (+)-(3E)-Pinnatifidenyne via Abnormally Regioselective Pd(0)-Catalyzed Endocyclization.

scientific article published on 12 January 2018

Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton

scientific article published in December 2017

Asymmetric synthesis of vinylogous β-amino acids and their incorporation into mixed backbone oligomers.

scientific article

Conformationally-Inspired Total Syntheses of Ohmyungsamycins A and B and Structural Revision of Ohmyungsamycin B.

scientific article published on 30 January 2018

DNA-compatible solid-phase combinatorial synthesis of β-cyanoacrylamides and related electrophiles.

scientific article published on 3 January 2018

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity

scientific article published on 08 December 2015

Design and synthesis of a macrosphelide A-biotin chimera

scientific article published on 01 September 2014

Design, synthesis and identification of novel colchicine-derived immunosuppressant.

scientific article

Diastereoselective Total Synthesis of (-)-Galiellalactone

scientific article published on 13 November 2015

Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone

scientific article published on 08 December 2015

Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE)

scientific article

Glucal-conjugated sterols as novel vascular leakage blocker: structure-activity relationship focusing on the C17-side chain.

scientific article published on 25 January 2014

Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors

scientific article

Identification and Structural Analysis of New Nrf2 Activators by Mechanism-Based Chemical Transformation of 15-Deoxy-Δ12, 14 -PGJ2.

scientific article published on 25 July 2016

Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism.

scientific article published on 12 December 2015

Identification of small molecule inhibitors of the STAT3 signaling pathway: Insights into their structural features and mode of action.

scientific article published on 26 July 2015

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

scientific article published on 09 October 2018

Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE)

scientific article (publication date: 22 May 2014)

Stereoselective Synthesis of 1,4,5-Tri-cis-guaiane Sesquiterpene: First Total Synthesis of (-)-Dendroside C Aglycon.

scientific article published on 16 January 2018

Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

scientific article published on 16 June 2015

Total synthesis of (+)-brasilenyne via concise construction of an oxonane framework containing a 1,3-cis,cis-diene

scientific article published on 01 January 2018

Total synthesis of (-)-deguelin via an iterative pyran-ring formation strategy.

scientific article published in May 2015

List of works by Hongchan An

Asymmetric Total Synthesis of (+)-(3E)-Pinnatifidenyne via Abnormally Regioselective Pd(0)-Catalyzed Endocyclization.

Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton

Asymmetric synthesis of vinylogous β-amino acids and their incorporation into mixed backbone oligomers.

Conformationally-Inspired Total Syntheses of Ohmyungsamycins A and B and Structural Revision of Ohmyungsamycin B.

DNA-compatible solid-phase combinatorial synthesis of β-cyanoacrylamides and related electrophiles.

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity

Design and synthesis of a macrosphelide A-biotin chimera

Design, synthesis and identification of novel colchicine-derived immunosuppressant.

Diastereoselective Total Synthesis of (-)-Galiellalactone

Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone

Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE)

Glucal-conjugated sterols as novel vascular leakage blocker: structure-activity relationship focusing on the C17-side chain.

Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors

Identification and Structural Analysis of New Nrf2 Activators by Mechanism-Based Chemical Transformation of 15-Deoxy-Δ12, 14 -PGJ2.

Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism.

Identification of small molecule inhibitors of the STAT3 signaling pathway: Insights into their structural features and mode of action.

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE)

Stereoselective Synthesis of 1,4,5-Tri-cis-guaiane Sesquiterpene: First Total Synthesis of (-)-Dendroside C Aglycon.

Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

Total synthesis of (+)-brasilenyne via concise construction of an oxonane framework containing a 1,3-cis,cis-diene

Total synthesis of (-)-deguelin via an iterative pyran-ring formation strategy.