List of works - Stefan K Siwko

A betulinic acid derivative SH479 inhibits collagen-induced arthritis by modulating T cell differentiation and cytokine balance.

scientific article published on 10 December 2016

Correction to: Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants

scientific article published on 01 September 2019

Dual Targeting of Bile Acid Receptor-1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen-Dependent Bone Loss in Mice

scientific article published on 07 January 2019

Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer

scientific article published on 11 September 2008

Exploring Rak tyrosine kinase function in breast cancer.

scientific article published on 15 August 2009

G-protein coupled receptor 124 (GPR124) in endothelial cells regulates vascular endothelial growth factor (VEGF)-induced tumor angiogenesis.

scientific article published on May 2014

GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.

scientific article published on 5 September 2013

Genome-wide transcriptome profiling of homologous recombination DNA repair

scientific article

Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants.

scientific article

Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization

scientific article published on 02 July 2018

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis ⬇️

scientific article published on December 1, 2012

KiSS1-induced GPR54 signaling inhibits breast cancer cell migration and epithelial-mesenchymal transition via protein kinase D1.

scientific article

Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity

scientific article published on 08 August 2018

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.

scientific article

LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.

scientific article published on 21 December 2017

LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.

scientific article published on 11 February 2014

Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors.

scientific article published on July 2008

Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.

scientific article published on 2 August 2017

Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.

scientific article

Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.

scientific article

Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.

scientific article published on September 2013

Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells

scientific article published on 07 December 2018

Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses

article

PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB.

scientific article

Prostate-Specific G-Protein Coupled Receptor, an Emerging Biomarker Regulating Inflammation and Prostate Cancer Invasion.

scientific article

Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression

scientific article published in June 2015

Regulation of body length and bone mass by Gpr126/Adgrg6

scientific article published on 20 March 2020

Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models

scientific article published on 29 May 2015

The role of GPCRs in bone diseases and dysfunctions

scientific article published on 08 July 2019

List of works by Stefan K Siwko

A betulinic acid derivative SH479 inhibits collagen-induced arthritis by modulating T cell differentiation and cytokine balance.

Correction to: Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants

Dual Targeting of Bile Acid Receptor-1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen-Dependent Bone Loss in Mice

Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer

Exploring Rak tyrosine kinase function in breast cancer.

G-protein coupled receptor 124 (GPR124) in endothelial cells regulates vascular endothelial growth factor (VEGF)-induced tumor angiogenesis.

GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.

Genome-wide transcriptome profiling of homologous recombination DNA repair

Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants.

Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis ⬇️

KiSS1-induced GPR54 signaling inhibits breast cancer cell migration and epithelial-mesenchymal transition via protein kinase D1.

Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.

LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.

LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.

Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors.

Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.

Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.

Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.

Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.

Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells

Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses

PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB.

Prostate-Specific G-Protein Coupled Receptor, an Emerging Biomarker Regulating Inflammation and Prostate Cancer Invasion.

Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression

Regulation of body length and bone mass by Gpr126/Adgrg6

Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models

The role of GPCRs in bone diseases and dysfunctions