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List of works by Dimitris K Grammatopoulos

ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis

scientific article published on 25 March 2021

Activation of protein kinase C by oxytocin inhibits the biological activity of the human myometrial corticotropin-releasing hormone receptor at term

scientific article published on 01 February 1999

Antenatal screening for fetal trisomies using microarray-based cell-free DNA testing: A systematic review and meta-analysis

scientific article published on 21 December 2019

Authors response to Stergiakouli et al.

scientific article published on 5 May 2014

Bacteriophage K1F targets Escherichia coli K1 in cerebral endothelial cells and influences the barrier function

scientific article published on 01 June 2020

CRH Receptor Signalling: Potential Roles in Pathophysiology.

scientific article

CRH-R splicing in estrogen-sensitive breast cancer

scientific article published on 21 January 2014

Characterising the corticotropin-releasing hormone (CRH) receptors mediating CRH and urocortin actions during human pregnancy and labour.

scientific article published on December 2001

Characterization of Structural Determinants of Type 1 Corticotropin Releasing Hormone (CRH) Receptor Signalling Properties ⬇️

scientific article published on January 1, 2010

Corticotropin-Releasing Hormone As the Homeostatic Rheostat of Feto-Maternal Symbiosis and Developmental Programming In Utero and Neonatal Life

scientific article published on 11 July 2017

Corticotropin-releasing hormone interacts with interleukin-1β to regulate prostaglandin H synthase-2 expression in human myometrium during pregnancy and labor.

scientific article published on 10 May 2013

Cyclic AMP enhances progesterone action in human myometrial cells.

scientific article published on 24 October 2013

Cyclic AMP increases COX‐2 expression via mitogen‐activated kinase in human myometrial cells ⬇️

scientific article published on July 1, 2012

Determining the stress biomarker profile in patients undergoing total knee replacement and the relationship with outcome at 12 months

scientific article published on 28 September 2019

Estrogen alters the splicing of type 1 corticotropin-releasing hormone receptor in breast cancer cells.

scientific article published on 2 July 2013

Expression and signalling characteristics of the corticotrophin-releasing hormone receptors during the implantation phase in the human endometrium.

scientific article published in February 2004

Extra-nuclear telomerase reverse transcriptase (TERT) regulates glucose transport in skeletal muscle cells

scientific journal article

Familial Hypercholesterolemia: New Horizons for Diagnosis and Effective Management

scientific article published on 12 July 2018

Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists

scientific article (publication date: December 2002)

Glyoxalase 1 copy number variation in patients with well differentiated gastro-entero-pancreatic neuroendocrine tumours (GEP-NET).

scientific article published on 16 August 2017

Hormonal regulation of placental nitric oxide and pathogenesis of pre-eclampsia

scientific article

Human corticotropin-releasing hormone receptor: differences in subtype expression between pregnant and nonpregnant myometria.

scientific article published in July 1998

Hypertestosteronemia and Infertility from a Mediastinal Extragonadal Germ Cell Tumor.

scientific article published in February 2017

Improved Thyroid Hypoechogenicity Following Bariatric-Induced Weight Loss in Euthyroid Adults With Severe Obesity-a Pilot Study

scientific article published on 24 August 2018

Inhibition of Akt activity and calcium channel function coordinately drive cell-cell fusion in the BeWO choriocarcinoma placental cell line

scientific article

Insights into mechanisms of corticotropin-releasing hormone receptor signal transduction.

scientific article

Interplay of cAMP and MAPK pathways in hCG secretion and fusogenic gene expression in a trophoblast cell line.

scientific article published on 28 October 2010

Intracellular mechanisms regulating corticotropin-releasing hormone receptor-2beta endocytosis and interaction with extracellularly regulated kinase 1/2 and p38 mitogen-activated protein kinase signaling cascades.

scientific article

Mapping Structural Determinants within Third Intracellular Loop That Direct Signaling Specificity of Type 1 Corticotropin-releasing Hormone Receptor ⬇️

scientific article published on January 13, 2012

Metabolic phenotype of male obesity-related secondary hypogonadism pre-replacement and post-replacement therapy with intra-muscular testosterone undecanoate therapy

scientific article published on 2 February 2018

Modelling of psychosocial and lifestyle predictors of peripartum depressive symptoms associated with distinct risk trajectories: a prospective cohort study

scientific article published in Scientific Reports

Molecular determinants and feedback circuits regulating type 2 CRH receptor signal integration

scientific article published on 19 February 2011

Molecular testing for familial hypercholesterolaemia-associated mutations in a UK-based cohort: development of an NGS-based method and comparison with multiplex polymerase chain reaction and oligonucleotide arrays

scientific article published on 28 September 2016

Pathological interactions with the timing of birth and uterine activation.

scientific article published on December 2007

Potential signalling pathways underlying corticotrophin-releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus.

scientific article published in February 2002

Preeclampsia is associated with impaired regulation of the placental nitric oxide-cyclic guanosine monophosphate pathway by corticotropin-releasing hormone (CRH) and CRH-related peptides

scientific article published on 22 March 2005

Protein kinase A-induced negative regulation of the corticotropin-releasing hormone R1alpha receptor-extracellularly regulated kinase signal transduction pathway: the critical role of Ser301 for signaling switch and selectivity.

scientific article

Reduced expression of corticotropin-releasing hormone receptor type-1 alpha in human preeclamptic and growth-restricted placentas.

scientific article

Regulation of G-protein coupled receptor signalling underpinning neurobiology of mood disorders and depression.

scientific article published on 13 February 2017

Role of corticotropin-releasing hormone in onset of labour

scientific article published on 01 October 1999

Severe paraneoplastic hypoglycemia secondary to a gastrointestinal stromal tumour masquerading as a stroke

scientific article

Signal transduction characteristics of the corticotropin-releasing hormone receptors in the feto-placental unit

scientific article published on 01 May 2000

Solubilization and biochemical characterization of the human myometrial corticotrophin-releasing hormone receptor ⬇️

scientific article published on March 16, 1998

Structural domains determining signalling characteristics of the CRH-receptor type 1 variant R1beta and response to PKC phosphorylation.

scientific article

The Onset of Labor Alters Corticotropin-Releasing Hormone Type 1 Receptor Variant Expression in Human Myometrium: Putative Role of Interleukin-1β

scientific article published on 12 April 2007

The biological activity of the corticotropin-releasing hormone receptor-adenylate cyclase complex in human myometrium is reduced at the end of pregnancy

scientific article published on 01 February 1996

The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms

scientific article published on 5 September 2014

The human myometrial CRH receptor: G proteins and second messengers

scientific article published on 01 March 1994

The human myometrium expresses multiple isoforms of the corticotropin-releasing hormone receptor

scientific article published on 01 August 1995

The human placenta and fetal membranes express the corticotropin-releasing hormone receptor 1alpha (CRH-1alpha) and the CRH-C variant receptor

scientific article published on 01 April 1998

The identification of a human myometrial corticotropin-releasing hormone receptor that increases in affinity during pregnancy.

scientific article published in March 1993

The identification of mitochondrial DNA variants in glioblastoma multiforme

scientific article published on 02 January 2014

The molecular mechanisms underlying the regulation of the biological activity of corticotropin-releasing hormone receptors: implications for physiology and pathophysiology.

scientific article

The role of corticotropin-releasing hormone receptors in placenta and fetal membranes during human pregnancy.

scientific article

Up-regulation of nitric oxide synthase and modulation of the guanylate cyclase activity by corticotropin-releasing hormone but not urocortin II or urocortin III in cultured human pregnant myometrial cells

scientific article

Urocortin II is expressed in human pregnant myometrial cells and regulates myosin light chain phosphorylation: potential role of the type-2 corticotropin-releasing hormone receptor in the control of myometrial contractility

scientific article (publication date: February 2004)

Urocortin, but not corticotropin-releasing hormone (CRH), activates the mitogen-activated protein kinase signal transduction pathway in human pregnant myometrium: an effect mediated via R1alpha and R2beta CRH receptor subtypes and stimulation of Gq-

scientific article

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