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List of works by Charles Craddock

A comparative assessment of the curative potential of reduced intensity allografts in acute myeloid leukaemia

scientific article published on 07 November 2014

A comparison between allogeneic stem cell transplantation from unmanipulated haploidentical and unrelated donors in acute leukemia.

scientific article published on 19 January 2017

A comparison of prophylactic vs pre-emptive ganciclovir to prevent cytomegalovirus disease after T-depleted volunteer unrelated donor bone marrow transplantation

scientific article published on 01 April 1999

ABO incompatibility in mismatched unrelated donor allogeneic hematopoietic cell transplantation for acute myeloid leukemia: A report from the acute leukemia working party of the EBMT.

scientific article published on 25 April 2017

Acquired isodisomy for chromosome 13 is common in AML, and associated with FLT3-itd mutations

scientific article published on 01 December 2005

Acquired isodisomy on chromosome 13 at diagnosis results in impaired overall survival in patients with FLT3-ITD mutant acute myeloid leukaemia.

scientific article

Acute myeloid leukaemia therapeutic innovation and clinical trials: past, present and future

scientific article published on 01 November 2020

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers

scientific article

Allogeneic Stem Cell Transplantation for Myelodysplastic Syndrome Patients with a 5q Deletion.

scientific article

Allogeneic haematopoietic stem cell transplant in patients with lower risk myelodysplastic syndrome: a retrospective analysis on behalf of the Chronic Malignancy Working Party of the EBMT.

scientific article published on 7 November 2016

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia

scientific article

Allogeneic stem cell transplantation benefits for patients ≥ 60 years with acute myeloid leukemia and FLT3 internal tandem duplication: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

scientific article published on 14 December 2017

Allogeneic stem cell transplantation in patients with atypical chronic myeloid leukaemia: a retrospective study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

scientific article published on 28 March 2017

Allogeneic transplantation in primary refractory AML

scientific article published on 24 April 2017

Alternative donors for allogeneic hematopoietic stem cell transplantation in poor-risk AML in CR1

scientific article published on 28 February 2017

An operational definition of primary refractory acute myeloid leukemia allowing early identification of patients who may benefit from allogeneic stem cell transplantation

scientific article published on 18 August 2016

Antilymphocyte Globulin for matched sibling donor transplantation in patients with myelofibrosis

scientific article published on 17 January 2019

Association of Macroeconomic Factors With Nonrelapse Mortality After Allogeneic Hematopoietic Cell Transplantation for Adults With Acute Lymphoblastic Leukemia: An Analysis From the Acute Leukemia Working Party of the EBMT.

scientific article published on 11 February 2016

Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT.

scientific article

Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)

scientific article published on 10 January 2012

Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia

scientific article

BEAM-alemtuzumab reduced-intensity allogeneic stem cell transplantation for lymphoproliferative diseases: GVHD, toxicity, and survival in 65 patients.

scientific article published on 11 September 2003

Biology and management of relapsed acute myeloid leukaemia.

scientific article

Bone marrow transplantation in the United Kingdom - past, present and future

scientific article published on 01 November 2020

Bortezomib, low-dose intravenous melphalan, and dexamethasone for patients with relapsed multiple myeloma

scientific article

CC-486 Maintenance after Stem Cell Transplantation in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndromes

scientific article published on 20 June 2018

CD8(+) T-cell immunity against cancer-testis antigens develops following allogeneic stem cell transplantation and reveals a potential mechanism for the graft-versus-leukemia effect.

scientific article

CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation.

scientific article

Characterization of CMV-specific CD4+ T-cell reconstitution following stem cell transplantation through the use of HLA Class II-peptide tetramers identifies patients at high risk of recurrent CMV reactivation.

scientific article published on 14 May 2015

Chemokine-mediated tissue recruitment of CXCR3+ CD4+ T cells plays a major role in the pathogenesis of chronic GVHD

scientific article published on 25 September 2012

Chromosomal stabilisation by a subtelomeric rearrangement involving two closely related Alu elements.

scientific article published in August 1996

Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells

scientific article published on 06 November 2003

Clinical activity of azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia.

scientific article published on 14 April 2016

Clinical evaluation of treatment with ciprofloxacin

scientific article published on 01 April 1986

Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation

scientific article published in June 2005

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

scientific article published on 01 January 2011

Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia

scientific article published on 17 January 2019

Comparable outcomes of haploidentical, 10/10 and 9/10 unrelated donor transplantation in adverse karyotype AML in first complete remission

scientific article published on 03 September 2018

Comparison of Intensive Chemotherapy and Hypomethylating Agents before Allogeneic Stem Cell Transplantation for Advanced Myelodysplastic Syndromes: A Study of the Myelodysplastic Syndrome Subcommittee of the Chronic Malignancies Working Party of the

scientific article

Comparison of unrelated cord blood and peripheral blood stem cell transplantation in adults with myelodysplastic syndrome after reduced-intensity conditioning regimen: a collaborative study from Eurocord (Cord blood Committee of Cellular Therapy & I

scientific article published on 19 December 2014

Conditioning intensity in HCT for AML: the jury is still out

scientific article published on 14 March 2018

Cord Blood Unit Dominance Analysis and Effect of the Winning Unit on Outcomes after Double-Unit Umbilical Cord Blood Transplantation in Adults with Acute Leukemia: A Retrospective Study on Behalf of Eurocord, the Cord Blood Committee of Cellular The

scientific article published on 01 March 2018

Cross-intolerance to imatinib, dasatinib and nilotinib therapy in a patient with chronic myeloid leukaemia

scientific article published on 01 June 2011

Cryopreservation of allogeneic PBSC from related and unrelated donors is associated with delayed platelet engraftment but has no impact on survival.

scientific article published on 25 June 2012

Cytomegalovirus seropositivity adversely influences outcome after T-depleted unrelated donor transplant in patients with chronic myeloid leukaemia: the case for tailored graft-versus-host disease prophylaxis

scientific article published on 01 January 2001

Distinct factors determine the kinetics of disease relapse in adults transplanted for acute myeloid leukaemia.

scientific article published on 7 December 2017

Donor KIR genotype has a major influence on the rate of cytomegalovirus reactivation following T-cell replete stem cell transplantation

scientific article published on 20 October 2005

Dose Transition Pathways: The Missing Link Between Complex Dose-Finding Designs and Simple Decision-Making

scientific article published on 21 July 2017

EBV-associated post-transplant lymphoproliferative disorder following in vivo T-cell-depleted allogeneic transplantation: clinical features, viral load correlates and prognostic factors in the rituximab era.

scientific article published on 11 November 2013

Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia

scientific article published on 01 March 2001

Embracing model-based designs for dose-finding trials. ⬇️

scientific article

Enshrining donor rights and optimizing patient outcome in unrelated donor transplantation

scientific article published on 01 November 2010

Epigenetic manipulation of the immune response: a novel treatment strategy in hematologic malignancies ⬇️

scientific article published on 07 March 2011

Estimation of current leukaemia-free survival following donor lymphocyte infusion therapy for patients with leukaemia who relapse after allografting: application of a multistate model

scientific article published on 01 November 2000

Evidence for a GVL effect following reduced-intensity allo-SCT in ALL: a British Society of Blood and Marrow Transplantation study ⬇️

scientific article published on January 14, 2013

Evidence for different mechanisms of 'unhooking' for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples.

scientific article

Exacerbation of IgA nephropathy following G-CSF administration for PBSC collection: suggestions for better donor screening

scientific article published on 05 October 2015

Expanding transplant options to patients over 50 years. Improved outcome after reduced intensity conditioning mismatched-unrelated donor transplantation for patients with acute myeloid leukemia: a report from the Acute Leukemia Working Party of the

scientific article published on 11 March 2016

Facial flushing and localized Castleman's disease: an extension of the POEMS syndrome phenotype

scientific article published on 01 February 2003

Factors predicting long-term survival after T-cell depleted reduced intensity allogeneic stem cell transplantation for acute myeloid leukemia

scientific article

Factors predicting outcome after unrelated donor stem cell transplantation in primary refractory acute myeloid leukaemia

scientific article published on 22 February 2011

Fasting: starving cancer

scientific article published in April 2017

Favorable outcomes with alemtuzumab-conditioned unrelated donor stem cell transplantation in adults with high-risk Philadelphia chromosome-negative acute lymphoblastic leukemia in first complete remission

scientific article published on 31 July 2009

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

scientific article published on March 2011

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

scientific article published on 04 July 2016

Greatly reduced risk of EBV reactivation in rituximab-experienced recipients of alemtuzumab-conditioned allogeneic HSCT. ⬇️

scientific article

Guidelines for the diagnosis and management of acute myeloid leukaemia in pregnancy

scientific article published on 17 June 2015

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution

scientific article published on 01 June 2002

High-dose busulphan alone as cytoreduction before allogeneic or autologous stem cell transplantation for chronic myeloid leukaemia: a single-centre experience

scientific article published on 01 March 2000

High-dose etoposide with granulocyte colony-stimulating factor for mobilization of peripheral blood progenitor cells: efficacy and toxicity at three dose levels ⬇️

scientific article published on October 1, 1998

High-hyperdiploidy in Philadelphia positive adult acute lymphoblastic leukaemia: case-series and review of literature.

scientific article

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

scientific article published in October 2005

Imatinib mesylate (STI571) in the treatment of relapse of chronic myeloid leukemia after allogeneic stem cell transplantation

scientific article published in May 2002

Imatinib or transplant for chronic myeloid leukaemia?

scientific article

Immune haemolytic anaemia following T cell-depleted allogeneic bone marrow transplantation for chronic myeloid leukaemia: association with leukaemic relapse and treatment with donor lymphocyte infusions.

scientific article

Impact of Alemtuzumab Scheduling on Graft-versus-Host Disease after Unrelated Donor Fludarabine and Melphalan Allografts

scientific article published on 14 February 2017

Impact of in vivo T-cell depletion on outcome of AML patients in first CR given peripheral blood stem cells and reduced-intensity conditioning allo-SCT from a HLA-identical sibling donor: a report from the Acute Leukemia Working Party of the Europea

scientific article

Impact of patient: donor HLA disparity on reduced-intensity-conditioned allogeneic stem cell transplants from HLA mismatched unrelated donors for AML: from the ALWP of the EBMT

scientific article published on 02 October 2020

Improving Outcomes in High-Risk Myelodysplasia: Festina Lente

scientific article published on 26 May 2017

Incidence, Risk Factors and Long-Term Outcome of Acute Leukemia Patients with Early Candidemia after Allogeneic Stem Cell Transplantation. A Study by the Acute Leukemia and Infectious Diseases Working Parties of EBMT.

scientific article published on 22 February 2018

Increased acute GvHD and higher transplant-related mortality in non-caucasians undergoing standard sibling allogeneic stem cell transplantation

scientific article published on 01 February 2006

Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses

scientific article published on 01 November 1988

Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

scientific article

Influence of pre-existing invasive aspergillosis on allo-HSCT outcome: a retrospective EBMT analysis by the Infectious Diseases and Acute Leukemia Working Parties

scientific article published on 26 October 2015

Integrating pharmacogenetics and therapeutic drug monitoring: optimal dosing of imatinib as a case-example.

scientific article published on 29 January 2010

Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen

scientific article published in February 2002

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

scientific article

Matched and mismatched unrelated donor compared to autologous stem cell transplantation for acute myeloid leukemia in first complete remission: a retrospective, propensity score-weighted analysis from the ALWP of the EBMT

scientific article

Matched unrelated donor allogeneic transplantation provides comparable long-term outcome to HLA-identical sibling transplantation in relapsed diffuse large B-cell lymphoma.

scientific article

Memory B-cell reconstitution following allogeneic hematopoietic stem cell transplantation is an EBV-associated transformation event

scientific article published on 8 October 2015

Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse

article

Molecularly targeted therapy in myeloid leukaemias.

scientific article published on December 2007

Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia

scientific article published on 14 December 2016

Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia.

scientific article published on 05 October 2014

NK cells produce high levels of IL-10 early after allogeneic stem cell transplantation and suppress development of acute GVHD.

scientific article

Origin and subset distribution of peripheral blood dendritic cells in patients with chronic graft-versus-host disease1

scientific article published on 01 January 2003

Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature.

scientific article published in August 2017

Outcome of second allogeneic transplants using reduced-intensity conditioning following relapse of haematological malignancy after an initial allogeneic transplant.

scientific article published on 25 August 2008

Outcomes following 50 mg versus 100 mg alemtuzumab in reduced-intensity conditioning stem cell transplants for acute myeloid leukaemia and poor risk myelodysplasia

scientific article published on 19 May 2008

Pertussis: should we vaccinate post transplant?

scientific article published on 01 April 2006

Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant

scientific article published on 05 February 2013

Posttransplantation imatinib as a strategy to postpone the requirement for immunotherapy in patients undergoing reduced-intensity allografts for chronic myeloid leukemia

scientific article published on 19 September 2007

Prediction of Allogeneic Hematopoietic Stem-Cell Transplantation Mortality 100 Days After Transplantation Using a Machine Learning Algorithm: A European Group for Blood and Marrow Transplantation Acute Leukemia Working Party Retrospective Data [...]

scientific article

Professor David Grimwade (1962-2016)

scientific article published on 16 January 2017

Prognostic value of monitoring a candidate immunophenotypic leukaemic stem/progenitor cell population in patients allografted for acute myeloid leukaemia

scientific article

Realising the potential of targeted therapies in oncology

scientific article published on 01 August 2002

Recommendations for a standard UK approach to incorporating umbilical cord blood into clinical transplantation practice: an update on cord blood unit selection, donor selection algorithms and conditioning protocols.

scientific article

Recommendations for a standard UK approach to incorporating umbilical cord blood into clinical transplantation practice: conditioning protocols and donor selection algorithms.

scientific article published on 12 January 2009

Reduced CD38 expression on CD34+ cells as a diagnostic test in myelodysplastic syndromes

scientific article published on August 2009

Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma.

scientific article

Reprint of: Allogeneic hematopoietic cell transplantation for acute myeloid leukemia

scientific article

Rituximab is effective in the management of refractory autoimmune cytopenias occurring after allogeneic stem cell transplantation.

scientific article

Role of HCT-comorbidity index, age and disease status at transplantation in predicting survival and non-relapse mortality in patients with myelodysplasia and leukemia undergoing reduced-intensity-conditioning hemopoeitic progenitor cell transplantat

scientific article published on 11 July 2011

Role of Nonmyeloablative Allogeneic Stem-Cell Transplantation After Failure of Autologous Transplantation in Patients With Lymphoproliferative Malignancies

scientific article published on 01 October 2002

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.

scientific article

Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity ⬇️

scientific article published on August 1, 1995

Stem cell transplantation after salvage therapy with high-dose cytarabine and amsacrine in adults with high-risk leukaemia.

scientific article published on August 2003

Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers

scientific article

Stratified medicine in practice: review of predictive biomarkers in European Medicines Agency (EMA) indications.

scientific article

Subsequent donation requests among 2472 unrelated hematopoietic progenitor cell donors are associated with bone marrow harvest ⬇️

scientific article published on June 28, 2013

Successful use of Campath-1H in the treatment of steroid refractory liver GvHD.

scientific article published in August 2004

Survival after bone-marrow transplantation

scientific article published on 01 March 2002

T-cell depletion does not necessarily compromise donor stem cell engraftment in patients receiving reduced-intensity conditioning regimens

scientific article published on 01 June 2003

Targeting the arginine metabolic brake enhances immunotherapy for leukaemia

scientific article published on 11 January 2019

The number of CD56dim NK cells in the graft has a major impact on risk of disease relapse following allo-HSCT

scientific article published on 21 August 2017

The role of CS1 moiety of fibronectin in VLA mediated haemopoietic progenitor trafficking

scientific article published on 01 April 1997

The role of allogeneic SCT in primary myelofibrosis: a British Society for Blood and Marrow Transplantation study.

scientific article published on 15 February 2010

The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience

scientific article published on 10 December 2019

The use of a national transplant registry to benchmark transplant outcome for patients undergoing autologous and allogeneic stem cell transplantation in the United Kingdom and Ireland

scientific article published on 01 February 2004

Tolerability and Clinical Activity of Post-Transplantation Azacitidine in Patients Allografted for Acute Myeloid Leukemia Treated on the RICAZA Trial

scientific article published on 9 September 2015

Topical issues in unrelated donor haematopoietic stem cell transplants: a report from a workshop convened by the Anthony Nolan Trust in London - 2005.

scientific article

Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.

scientific article published in December 2001

Tyrosine kinase inhibitors improve long-term outcome of allogeneic hematopoietic stem cell transplantation for adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia

scientific article

Unique features and clinical importance of acute alloreactive immune responses.

scientific article

Unrelated Cord Blood Transplantation in adults: evolution, experience and long-term outcomes in the UK National Health Service : a retrospective analysis on behalf of the British Society of Blood and Marrow Transplantation and Eurocord

scientific article published on 27 December 2015

Unrelated donor peripheral blood stem cell transplants incorporating pre-transplant in-vivo alemtuzumab are not associated with any increased risk of significant acute or chronic graft-versus-host disease.

scientific article published on 8 March 2011

Who is the best hematopoietic stem-cell donor for a male patient with acute leukemia?

scientific article published in September 2014

Wilms' Tumour 1 (WT1) peptide vaccination in patients with acute myeloid leukaemia induces short-lived WT1-specific immune responses

scientific article

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