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List of works by Miguel Diaz-Hernandez

Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

scientific article published in March 2010

Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration.

scientific article published on 26 January 2009

Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain.

scientific article published in October 2004

Cloning and characterization of two novel zebrafish P2X receptor subunits.

scientific article

Co-localisation of functional nicotinic and ionotropic nucleotide receptors in isolated cholinergic synaptic terminals ⬇️

scientific article published on January 1, 2002

Diadenosine polyphosphate receptors. from rat and guinea-pig brain to human nervous system.

scientific article

Diadenosine tetraphosphate contributes to carbachol-induced tear secretion.

scientific article published on 15 November 2014

Enhanced induction of the immunoproteasome by interferon gamma in neurons expressing mutant Huntingtin.

scientific article published in January 2004

Extracellular tau is toxic to neuronal cells.

scientific article published on 8 August 2006

Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells

scientific journal article

Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease.

scientific article

Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.

scientific article published on 28 June 2013

Independent receptors for diadenosine pentaphosphate and ATP in rat midbrain single synaptic terminals.

scientific article

Interaction between dinucleotide and nicotinic receptors in individual cholinergic terminals.

scientific article published on 13 July 2004

Is the ubiquitin-proteasome system impaired in Huntington's disease?

scientific article published on September 2007

Looking for novel functions of tau.

scientific article published on August 2012

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.

scientific article published on 7 October 2010

Modulation of the rat hippocampal dinucleotide receptor by adenosine receptor activation.

scientific article published in May 2002

Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology.

scientific article published in July 2017

P2X receptors as targets for the treatment of status epilepticus

scientific article

P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage

scientific article published on 21 April 2014

P2X7 receptors in rat brain: presence in synaptic terminals and granule cells.

scientific article published in October 2003

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.

scientific article

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

scientific article published on 4 September 2009

Role of CaCMKII in the cross talk between ionotropic nucleotide and nicotinic receptors in individual cholinergic terminals.

scientific article published in January 2006

Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice.

scientific article published on 23 December 2011

Sources of extracellular tau and its signaling.

scientific article published on January 2014

TNAP Plays a Key Role in Neural Differentiation as well as in Neurodegenerative Disorders.

scientific article published on January 2015

Tau Overexpression Results in Its Secretion via Membrane Vesicles

scientific article published on 21 January 2012

Tau triggers tear secretion by interacting with muscarinic acetylcholine receptors in New Zealand white rabbits

scientific article published in January 2014

Testing the ubiquitin-proteasome hypothesis of neurodegeneration in vivo.

scientific article published on February 2004

The ubiquitin-proteasome system in Huntington's disease.

scientific article

Tissue-nonspecific Alkaline Phosphatase Regulates Purinergic Transmission in the Central Nervous System During Development and Disease.

scientific article

Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy.

scientific article published in June 2016

microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus

scientific article

α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease.

scientific article

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