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List of works by Saverio Bettuzzi

A novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR.

scientific article

Anticancer activity of green tea polyphenols in prostate gland

scientific article

Chapter 1: Introduction.

scientific article published in January 2009

Chapter 2: Clusterin (CLU): From one gene and two transcripts to many proteins.

scientific article published on January 2009

Chapter 5: Nuclear CLU (nCLU) and the fate of the cell.

scientific article published on January 2009

Chronic administration of green tea extract to TRAMP mice induces the collapse of Golgi apparatus in prostate secretory cells and results in alterations of protein post-translational processing.

scientific article published on 20 July 2011

Cisplatin-resistance modulates the effect of protein synthesis inhibitors on spermidine/spermine N(1)-acetyltransferase expression.

scientific article published on January 2004

Clusterin (CLU) and lung cancer.

scientific article published on January 2009

Clusterin (CLU) and prostate cancer.

scientific article published on January 2009

Clusterin (SGP-2) transient overexpression decreases proliferation rate of SV40-immortalized human prostate epithelial cells by slowing down cell cycle progression.

scientific article published on June 2002

Clusterin (SGP-2, ApoJ) expression is downregulated in low- and high-grade human prostate cancer.

scientific article published on January 2004

Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism

scientific article published on 06 December 2019

Clusterin is a short half-life, poly-ubiquitinated protein, which controls the fate of prostate cancer cells.

scientific article

Clusterin isoforms differentially affect growth and motility of prostate cells: possible implications in prostate tumorigenesis.

scientific article published on November 2007

Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas

scientific article published on 28 April 2009

Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent.

scientific article

Conclusions and perspectives.

scientific article published on January 2009

Control of autophagy in cancer.

scientific article published on 10 March 2015

Coordinate changes of polyamine metabolism regulatory proteins during the cell cycle of normal human dermal fibroblasts

scientific article published on 01 March 1999

DNA and cell death.

scientific article published on February 1991

Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development.

scientific article

Different localization of spermidine/spermine N1-acetyltransferase and ornithine decarboxylase transcripts in the rat kidney

scientific article published on 01 December 1995

Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1,N12-bis(ethyl)spermine involves transcriptional and post-transcriptional regulation.

scientific article

Distinct promoters, subjected to epigenetic regulation, drive the expression of two clusterin mRNAs in prostate cancer cells.

scientific article

EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism

scientific article

Effet hépatoprotecteur et antiradicalaire d’un extrait butanolique de Rhantherium suaveolens

Establishment of an organotypic in vitro culture system and its relevance to the characterization of human prostate epithelial cancer cells and their stromal interactions

scientific article published on 01 January 2007

Gene relaxation and aging: changes in the abundance of rat ventral prostate SGP-2 (clusterin) and ornithine decarboxylase mRNAs

scientific article published on 01 July 1994

Genetic inactivation of ApoJ/clusterin: effects on prostate tumourigenesis and metastatic spread.

scientific article published in December 2009

Green Tea Catechins for Prostate Cancer Prevention: Present Achievements and Future Challenges.

scientific article

Green tea catechins suppress the DNA synthesis marker MCM7 in the TRAMP model of prostate cancer.

scientific article published on September 2007

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Heparin inhibits phorbol ester‐induced ornithine decarboxylase gene expression in endothelial cells

scientific article published on February 13, 1998

Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis

scientific article published on January 1989

In vivo accumulation of sulfated glycoprotein 2 mRNA in rat thymocytes upon dexamethasone-induced cell death

scientific article published on 01 March 1991

Increased levels of clusterin (SGP-2) mRNA and protein accompany rat ventral prostate involution following finasteride treatment

scientific article published on 01 November 2000

Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia.

scientific article published in April 2004

Inhibition of spontaneous and androgen-induced prostate growth by a nonhypercalcemic calcitriol analog

scientific article

Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells1.

scientific article published on September 2004

Intracellular clusterin negatively regulates ovarian chemoresistance: compromised expression sensitizes ovarian cancer cells to paclitaxel.

scientific article published on 15 July 2011

Molecular classification of green tea catechin-sensitive and green tea catechin-resistant prostate cancer in the TRAMP mice model by quantitative real-time PCR gene profiling.

scientific article published on 28 November 2005

Molecular mechanisms of the antimetastatic activity of nuclear clusterin in prostate cancer cells

scientific article published on May 3, 2011

Polyphenon E(R), a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis.

scientific article published on 16 December 2013

Prognostic role of clusterin in resected adenocarcinomas of the lung.

scientific article published on 28 December 2012

Regional increases in ornithine decarboxylase mRNA levels in the rat brain after partial mesodiencephalic hemitransection as revealed by in situ hybridization histochemistry.

scientific article

Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis.

scientific article

Roles of autophagy induced by natural compounds in prostate cancer

scientific article

SGP-2, apoptosis, and aging

scientific article published on 01 November 1992

Senescence, immortalization, and apoptosis. An intriguing relationship

scientific article published on December 26, 1992

Spermidine/spermine N1-acetyltransferase transient overexpression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin.

scientific article

Studies on the relationship between cell proliferation and cell death: opposite patterns of SGP-2 and ornithine decarboxylase mRNA accumulation in PHA-stimulated human lymphocytes

scientific article published on 01 October 1991

The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression.

scientific article published on 9 September 2004

The gene for SP-40,40, human homolog of rat sulfated glycoprotein 2, rat clusterin, and rat testosterone-repressed prostate message 2, maps to chromosome 8

scientific article published on 01 May 1991

mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer.

scientific article published on May 2012