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List of works by Xiao-Yan Wen

A Model of Excitotoxic Brain Injury in Larval Zebrafish: Potential Application for High-Throughput Drug Evaluation to Treat Traumatic Brain Injury.

scientific article

A call for rigorous study of statins in resolution of cerebral cavernous malformation pathology.

scientific article published on 06 May 2014

A deficiency in the region homologous to human 17q21.33-q23.2 causes heart defects in mice.

scientific article

Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia

scientific article

Advances in zebrafish high content and high throughput technologies.

scientific article published on August 2012

Characterization of the first knock-out aldh7a1 zebrafish model for pyridoxine-dependent epilepsy using CRISPR-Cas9 technology.

scientific article published on 20 October 2017

Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms

scientific article published on 20 August 2015

Could pharmacological curtailment of the RhoA/Rho-kinase pathway reverse the endothelial barrier dysfunction associated with Ebola virus infection?

scientific article

Development of a zebrafish sepsis model for high-throughput drug discovery.

scientific article published on 7 June 2017

Developmental processes regulated by the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway: highlights from animal studies.

scientific article published on 13 April 2014

Digital image correlation-based optical coherence elastography.

scientific article published on December 2013

Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly.

scientific article published on 06 February 2017

Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?

scientific article published on 8 April 2017

Effect of surfactant concentration on transdermal lidocaine delivery with linker microemulsions.

scientific article published on 2 April 2010

Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects

scientific article

Enhanced adaptive immunity in mice lacking the immunoinhibitory adaptor Hacs1

scientific journal article

Genetic mapping of two mouse homeobox genes Tlx-1 and Tlx-2 to murine chromosomes 19 and 6.

scientific article published in November 1994

Glutaminase Deficiency Caused by Short Tandem Repeat Expansion in

scientific article published on 01 April 2019

Histone acetyltransferase 7 (KAT7)-dependent intragenic histone acetylation regulates endothelial cell gene regulation.

scientific article published on 6 February 2018

Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans

scientific article (publication date: 15 May 2003)

Improved therapeutic outcome following combination immunogene vaccination therapy in murine myeloma

scientific article published on 01 October 2003

Integrating glycomics and genomics uncovers SLC10A7 as essential factor for bone mineralization by regulating post-Golgi protein transport and glycosylation

article published in 2018

Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage

scientific article

Murine phosphatidylserine-specific phospholipase A1 (Ps-pla1) maps to chromosome 16 but is distinct from the lpd (lipid defect) locus.

scientific article

NANS-mediated synthesis of sialic acid is required for brain and skeletal development

scientific article published on 23 May 2016

New Exploration of Chinese Herbal Medicines in Hepatology

scientific article published on 20 July 2016

Non-steric-zipper models for pathogenic α-synuclein conformers

scientific article published on 01 May 2018

Preclinical Models for Investigation of Herbal Medicines in Liver Diseases: Update and Perspective

scientific article

Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma

scientific journal article

Regulatory pathways affecting vascular stabilization via VE-cadherin dynamics: insights from zebrafish (Danio rerio)

scientific article

Remote Ischemic Conditioning Prevents Lung and Liver Injury After Hemorrhagic Shock/Resuscitation: Potential Role of a Humoral Plasma Factor

scientific article published on 01 June 2015

Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus

scientific article published on June 2016

Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer.

scientific article

SRD5A2 V89L polymorphism and prostate cancer risk: a meta-analysis.

scientific article published in February 2010

Simple animal models for amyotrophic lateral sclerosis drug discovery

scientific article published on June 2016

Simultaneous ultra-high frequency photoacoustic microscopy and photoacoustic radiometry of zebrafish larvae

scientific article published on 01 September 2018

Soluble interleukin-13Ralpha2 decoy receptor inhibits Hodgkin's lymphoma growth in vitro and in vivo.

scientific article published on May 2004

The Bcl-2 family protein inhibitor, ABT-737, has substantial antimyeloma activity and shows synergistic effect with dexamethasone and melphalan.

scientific article published on January 2007

The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis.

scientific article published on 10 September 2012

Uterine-derived stem cells reconstitute the bone marrow of irradiated mice.

scientific article

Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types

scientific article published on 28 May 2015

Zebrafish cancer and metastasis models for in vivo drug discovery

scientific article

Zebrafish heart failure models: opportunities and challenges.

scientific article

Zebrafish models of major depressive disorders

scientific article published on 09 October 2015

rbm47, a novel RNA binding protein, regulates zebrafish head development

scientific article published on 30 September 2013

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