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List of works by Xavier Guillonneau

A regulatory domain is required for Foxn4 activity during retinogenesis

scientific article

APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration

scientific article published on October 2015

Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-α.

scientific article published on 22 September 2016

Altered astrocyte morphology and vascular development in dystrophin-Dp71-null mice.

scientific article published on 29 December 2015

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

scientific article

Association of Choroidal Interleukin-17-Producing T Lymphocytes and Macrophages with Geographic Atrophy.

scientific article published on 10 June 2016

Both FGF1 and bcl-x synthesis are necessary for the reduction of apoptosis in retinal pigmented epithelial cells by FGF2: role of the extracellular signal-regulated kinase 2.

scientific article

CC5 and CC8, two homologous disintegrins from Cerastes cerastes venom, inhibit in vitro and ex vivo angiogenesis

scientific article published on 4 February 2016

CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration

scientific article published on 02 December 2010

CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice

scientific article published on 21 October 2013

CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents

scientific article (publication date: February 2008)

Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation.

scientific article published on 16 March 2018

Comment on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration" by Luhmann et al. (Exp. Eye Res. 2013; 107: 80.doi: 10.1016).

scientific article published on 10 February 2013

Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation.

scientific article published on February 2017

Complement factor H and related proteins in age-related macular degeneration

scientific article published on 25 February 2014

Control of the intracellular signaling induced by fibroblast growth factors (FGF) over the proliferation and survival of retinal pigment epithelium cells: example of the signaling regulation of growth factors endogenous to the retina

scientific article published in January 2001

Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization

scientific article published on 22 May 2020

Dystrophin Dp71 gene deletion induces retinal vascular inflammation and capillary degeneration

scientific article

Endogenous FGF1-induced activation and synthesis of extracellular signal-regulated kinase 2 reduce cell apoptosis in retinal-pigmented epithelial cells

scientific article published on 01 August 1998

Erratum to: Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.

scientific article published on 19 December 2012

Experimental Branch Retinal Vein Occlusion Induces Upstream Pericyte Loss and Vascular Destabilization

scientific article published on 24 July 2015

Expression and localization of dystrophins and β-dystroglycan in the hypothalamic supraoptic nuclei of rat from birth to adulthood

scientific article published on 28 December 2018

FGF2-stimulated release of endogenous FGF1 is associated with reduced apoptosis in retinal pigmented epithelial cells

scientific article published on 01 May 1997

Fibroblast growth factor (FGF) soluble receptor 1 acts as a natural inhibitor of FGF2 neurotrophic activity during retinal degeneration

scientific journal article

Glucagon-like Peptide 1 Receptor Agonists, Diabetic Retinopathy and Angiogenesis: The AngioSafe Type 2 Diabetes Study

scientific article published on 01 April 2020

IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis

scientific article published on 03 January 2020

In vitro changes in plasma membrane heparan sulfate proteoglycans and in perlecan expression participate in the regulation of fibroblast growth factor 2 mitogenic activity

scientific article published on 01 January 1996

Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration.

scientific article published on May 2011

Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells.

scientific article

Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells

scientific journal article

Iron, ferritin, transferrin, and transferrin receptor in the adult rat retina

scientific article published on 01 July 2000

Lebecetin, a C-type lectin, inhibits choroidal and retinal neovascularization.

scientific article published on 14 December 2016

MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.

scientific article

Mo-derived perivascular macrophage recruitment protects against endothelial cell death in retinal vein occlusion

scientific article published on 27 July 2019

Modifications to the classical rat aortic ring model to allow vascular degeneration studies

scientific article published on 21 January 2021

Neonatal hyperglycemia inhibits angiogenesis and induces inflammation and neuronal degeneration in the retina

scientific article

On phagocytes and macular degeneration

scientific article published on 7 June 2017

Paracrine effects of phosphorylated and excreted FGF1 by retinal pigmented epithelial cells

scientific article published on 01 January 1998

Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retina.

scientific article published on 31 July 2011

Regulation of proliferation-survival decisions is controlled by FGF1 secretion in retinal pigmented epithelial cells.

scientific article published in October 2000

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β.

scientific article published on 20 July 2016

TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness

scientific article

The familial dementia gene revisited: a missense mutation revealed by whole-exome sequencing identifies ITM2B as a candidate gene underlying a novel autosomal dominant retinal dystrophy in a large family.

scientific article

Thinning of the RPE and choroid associated with T lymphocyte recruitment in aged and light-challenged mice.

scientific article published on 2 September 2015

Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration.

scientific article published on May 2015

Use of suppression subtractive hybridization to identify genes regulated by ciliary neurotrophic factor in postnatal retinal explants.

scientific article

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