List of works - Lykke Sylow

AMPK and insulin action--responses to ageing and high fat diet

scientific article

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

scientific article

Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle.

scientific article published on 11 January 2015

Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance

scientific article

Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion

scientific article published on 24 January 2020

Circulating Follistatin and Activin A and Their Regulation by Insulin in Obesity and Type 2 Diabetes

scientific article published on 01 May 2020

Contraction-stimulated glucose transport in muscle is controlled by AMPK and mechanical stress but not sarcoplasmatic reticulum Ca(2+) release

scientific article

Current understanding of increased insulin sensitivity after exercise - emerging candidates.

scientific article published on 19 April 2011

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise

scientific article published on 11 October 2019

Decreased spontaneous activity in AMPK α2 muscle specific kinase dead mice is not caused by changes in brain dopamine metabolism.

scientific article published on 12 June 2016

Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity

scientific article

Differential effects of high-fat diet and exercise training on bone and energy metabolism

scientific article published on 20 July 2018

Effects of Roux-en-Y gastric bypass on circulating follistatin, activin A, and peripheral ActRIIB signaling in humans with obesity and type 2 diabetes

scientific article published on 01 September 2020

Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects

scientific article

Exercise Increases Human Skeletal Muscle Insulin Sensitivity via Coordinated Increases in Microvascular Perfusion and Molecular Signaling

scientific article published on 14 March 2017

Exercise-stimulated glucose uptake - regulation and implications for glycaemic control

scientific article

Housing temperature influences exercise training adaptations in mice

scientific article published on 25 March 2020

Insulin-stimulated glucose uptake partly relies on p21-activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle

scientific article published on 26 August 2020

Integrin-associated ILK and PINCH1 protein content are reduced in skeletal muscle of maintenance hemodialysis patients

scientific article published on 24 September 2020

Involvement of the extracellular matrix and integrin signalling proteins in skeletal muscle glucose uptake

scientific article published in 2022

Is contraction-stimulated glucose transport feedforward regulated by Ca2+?

scientific article

LKB1 regulates lipid oxidation during exercise independently of AMPK

scientific article published on 24 January 2013

Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice

scientific article published on 2 May 2017

Mechanisms involved in follistatin-induced hypertrophy and increased insulin action in skeletal muscle

scientific article published on 11 August 2019

Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise

scientific journal article

PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain

scientific article

Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry

scientific article published on 05 August 2019

Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.

scientific article published on 16 July 2018

Rac1 and AMPK Account for the Majority of Muscle Glucose Uptake Stimulated by Ex Vivo Contraction but Not In Vivo Exercise.

scientific article

Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice

scientific article

Rac1 in Muscle Is Dispensable for Improved Insulin Action After Exercise in Mice.

scientific article published on 10 June 2016

Rac1 is a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

scientific article

Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt.

scientific article

Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle

scientific article

Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle.

scientific article published on 13 June 2011

Rac1--a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

scientific article

Reply from Lykke Sylow, Lisbeth L. V. Møller, Maximilian Kleinert, Erik A. Richter and Thomas E. Jensen

scientific article published on 01 May 2015

Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1

scientific article

The Cancer Drug Dasatinib Increases PGC-1α in Adipose Tissue but Has Adverse Effects on Glucose Tolerance in Obese Mice

scientific article

The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport

scientific article published on 01 June 2020

Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells.

scientific article

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

scientific article published on 22 June 2016

β-Actin shows limited mobility and is required only for supraphysiological insulin-stimulated glucose transport in young adult soleus muscle

scientific article published on 13 March 2018

List of works by Lykke Sylow

AMPK and insulin action--responses to ageing and high fat diet

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle.

Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance

Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion

Circulating Follistatin and Activin A and Their Regulation by Insulin in Obesity and Type 2 Diabetes

Contraction-stimulated glucose transport in muscle is controlled by AMPK and mechanical stress but not sarcoplasmatic reticulum Ca(2+) release

Current understanding of increased insulin sensitivity after exercise - emerging candidates.

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise

Decreased spontaneous activity in AMPK α2 muscle specific kinase dead mice is not caused by changes in brain dopamine metabolism.

Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity

Differential effects of high-fat diet and exercise training on bone and energy metabolism

Effects of Roux-en-Y gastric bypass on circulating follistatin, activin A, and peripheral ActRIIB signaling in humans with obesity and type 2 diabetes

Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects

Exercise Increases Human Skeletal Muscle Insulin Sensitivity via Coordinated Increases in Microvascular Perfusion and Molecular Signaling

Exercise-stimulated glucose uptake - regulation and implications for glycaemic control

Housing temperature influences exercise training adaptations in mice

Insulin-stimulated glucose uptake partly relies on p21-activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle

Integrin-associated ILK and PINCH1 protein content are reduced in skeletal muscle of maintenance hemodialysis patients

Involvement of the extracellular matrix and integrin signalling proteins in skeletal muscle glucose uptake

Is contraction-stimulated glucose transport feedforward regulated by Ca2+?

LKB1 regulates lipid oxidation during exercise independently of AMPK

Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice

Mechanisms involved in follistatin-induced hypertrophy and increased insulin action in skeletal muscle

Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise

PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain

Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry

Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.

Rac1 and AMPK Account for the Majority of Muscle Glucose Uptake Stimulated by Ex Vivo Contraction but Not In Vivo Exercise.

Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice

Rac1 in Muscle Is Dispensable for Improved Insulin Action After Exercise in Mice.

Rac1 is a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt.

Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle

Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle.

Rac1--a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

Reply from Lykke Sylow, Lisbeth L. V. Møller, Maximilian Kleinert, Erik A. Richter and Thomas E. Jensen

Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1

The Cancer Drug Dasatinib Increases PGC-1α in Adipose Tissue but Has Adverse Effects on Glucose Tolerance in Obese Mice

The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport

Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells.

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

β-Actin shows limited mobility and is required only for supraphysiological insulin-stimulated glucose transport in young adult soleus muscle