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List of works by Sonia Colombo

A mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, specifically affects glucose- and acidification-induced cAMP signalling and not the basal cAMP level.

scientific article published on July 1999

Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae.

scientific article

Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).

scientific article

Design and characterization of a new class of inhibitors of ras activation

scientific article

Design, synthesis and biological evaluation of sugar-derived Ras inhibitors

scientific article published on October 2005

Design, synthesis, and biological evaluation of levoglucosenone-derived ras activation inhibitors.

scientific article

Detection of cAMP and of PKA activity in Saccharomyces cerevisiae single cells using Fluorescence Resonance Energy Transfer (FRET) probes.

scientific article published on 19 April 2017

Evidence for adenylate cyclase as a scaffold protein for Ras2-Ira interaction in Saccharomyces cerevisie

scientific article published on 8 February 2014

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

scientific article published on 13 August 2007

Involvement of Aif1 in apoptosis triggered by lack of Hxk2 in the yeast Saccharomyces cerevisiae.

scientific article published on 18 February 2016

Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae.

scientific article

Lack of HXK2 induces localization of active Ras in mitochondria and triggers apoptosis in the yeast Saccharomyces cerevisiae

scientific article published on 5 September 2013

Live-cell imaging of endogenous Ras-GTP shows predominant Ras activation at the plasma membrane and in the nucleus in Saccharomyces cerevisiae.

scientific article

Methods to study the Ras2 protein activation state and the subcellular localization of Ras-GTP in Saccharomyces cerevisiae.

scientific article published in January 2014

Nuclear Ras2-GTP controls invasive growth in Saccharomyces cerevisiae

scientific article published on 14 November 2013

Nutrient-induced signal transduction through the protein kinase A pathway and its role in the control of metabolism, stress resistance, and growth in yeast.

scientific article

Purification and characterization of a thermostable carboxypeptidase from the extreme thermophilic archaebacterium Sulfolobus solfataricus

scientific article published on June 1, 1992

Role of guanine nucleotides in the regulation of the Ras/cAMP pathway in Saccharomyces cerevisiae.

scientific article

Structural features responsible for kinetic thermal stability of a carboxypeptidase from the archaebacterium Sulfolobus solfataricus.

scientific article published on November 1993

Structure-activity studies on arylamides and arysulfonamides Ras inhibitors

scientific article published on March 2010

The large N-terminal domain of Cdc25 protein of the yeast Saccharomyces cerevisiae is required for glucose-induced Ras2 activation.

scientific article published on 29 August 2007

The role of feedback control mechanisms on the establishment of oscillatory regimes in the Ras/cAMP/PKA pathway in S. cerevisiae

scientific article

The transcription factor Swi4 is target for PKA regulation of cell size at the G1 to S transition in Saccharomyces cerevisiae

scientific article published on 5 June 2015

Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast

scientific article