List of works - Rajith Kumar Reddy Rajoli

A physiologically based pharmacokinetic model to predict the superparamagnetic iron oxide nanoparticles (SPIONs) accumulation in vivo

Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies.

scientific article published on 15 April 2015

Derivation of CYP3A4 and CYP2B6 degradation rate constants in primary human hepatocytes: A siRNA-silencing-based approach

scientific article published on 16 March 2018

Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis

scientific article published on 06 May 2020

Modelling of Systemic versus Pulmonary Chloroquine Exposure in Man for COVID-19 Dose Selection

scientific article published on 30 April 2020

Modelling the long-acting administration of anti-tuberculosis agents using PBPK: a proof of concept study

scientific article published on 01 August 2018

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes

scientific article

Physiologically Based Pharmacokinetic Modelling to Inform Development of Intramuscular Long-Acting Nanoformulations for HIV.

scientific article published on June 2015

Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug-drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART.

scientific article published on 22 January 2018

Physiologically based pharmacokinetic models for the optimization of antiretroviral therapy: recent progress and future perspective

Predicting Drug-Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling

scientific article published on 01 May 2019

Predicting pharmacokinetics of a tenofovir alafenamide subcutaneous implant using PBPK modelling

scientific article published on 18 May 2020

Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling

scientific article published on 01 March 2020

Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate target site concentrations derived from their established human pharmacokinetics

scientific article published on 22 April 2020

Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate.

scientific article published on 17 April 2017

The in vitro antiviral activity of the anti-hepatitis C virus (HCV) drugs daclatasvir and sofosbuvir against SARS-CoV-2