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List of works by Sebastian Halbach

Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells

scientific article published on 22 April 2013

Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

scientific article published on 24 February 2016

B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model

scientific article published on 18 January 2019

B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells

scientific article

BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines

scientific article published on 12 January 2018

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

scientific article

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

scientific article published on 01 April 2018

Exometabolom analysis of breast cancer cell lines: Metabolic signature

scientific article

Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia

scientific article published on 22 February 2019

Gab2 is essential for Bcr-Abl-mediated leukemic transformation and hydronephrosis in a chronic myeloid leukemia mouse model.

scientific article published on 29 April 2016

Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors.

scientific article

Metabolic profiling of breast cancer: Differences in central metabolism between subtypes of breast cancer cell lines

scientific article published on 14 July 2015

Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans

scientific article published on 01 October 2020

Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer.

scientific article

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

scientific article published in February 2018

Quantitative Proteomics Analysis of Leukemia Cells.

scientific article published on January 2016

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

scientific article published in 2024

Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface

scientific article

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

scientific article published on 12 February 2018

The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

scientific article published on 12 April 2017

The Versatile Role of Gab1 in the Circulatory System

scientific article published on 11 July 2012

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