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List of works by Alfred Fahr

A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs

scientific article

A new strategy to prepare temperature-sensitive poly(N-isopropylacrylamide) microgels

A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types

scientific article published on 11 October 2007

A remarkable self-organization process as the origin of primitive functional cells.

scientific article

Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously

scientific article published on 24 March 2017

Adaptive neuro-fuzzy modeling of poorly soluble drug formulations

scientific article published on 25 May 2006

Analysis of immobilized artificial membrane retention factors for both neutral and ionic species ⬇️

scientific article published on May 10, 2013

Analysis of liposomes using asymmetrical flow field-flow fractionation: separation conditions and drug/lipid recovery

scientific article

Antimicrobial peptide-modified liposomes for bacteria targeted delivery of temoporfin in photodynamic antimicrobial chemotherapy ⬇️

scientific article published on July 20, 2011

Assessment of fluidity of different invasomes by electron spin resonance and differential scanning calorimetry ⬇️

scientific article published on April 16, 2011

Asymmetric flow field-flow fractionation in the field of nanomedicine

scientific article published on 20 May 2014

Bispecific single-chain diabody-immunoliposomes targeting endoglin (CD105) and fibroblast activation protein (FAP) simultaneously

scientific article

Cellular uptake and degradation behaviour of biodegradable poly(ethylene glycol-graft-methyl methacrylate) nanoparticles crosslinked with dimethacryloyl hydroxylamine ⬇️

scientific article published on October 20, 2010

Cholesterol anchored arabinogalactan for asialoglycoprotein receptor targeting: synthesis, characterization, and proof of concept of hepatospecific delivery

scientific article published on 13 March 2015

Comparative SAXS and DSC study on stratum corneum structural organization in an epidermal cell culture model (ROC): impact of cultivation time

scientific article

Comparison of lipid membrane-water partitioning with various organic solvent-water partitions of neutral species and ionic species: Uniqueness of cerasome as a model for the stratum corneum in partition processes

scientific article

DHPC Strongly Affects the Structure and Oligomerization Propensity of Alzheimer's Aβ(1–40) Peptide ⬇️

scientific article published on September 17, 2010

Dataset on FAP-induced emergence of spontaneous metastases and on the preparation of activatable FAP-targeting immunoliposomes to detect the metastases

scientific article

Dataset on the role of endoglin expression on melanin production in murine melanoma and on the influence of melanin on optical imaging

Degradation kinetics of an aspartyl-tripeptide-derived diketopiperazine under forced conditions

scientific article published on 16 August 2012

Design of cholesterol arabinogalactan anchored liposomes for asialoglycoprotein receptor mediated targeting to hepatocellular carcinoma: In silico modeling, in vitro and in vivo evaluation

scientific article published on 23 May 2016

Development of different temoporfin-loaded invasomes-novel nanocarriers of temoporfin: characterization, stability and in vitro skin penetration studies

scientific article published on 27 December 2008

Development of hydrophilic gels containing coenzyme Q10-loaded liposomes: characterization, stability and rheology measurements

article

Development of liposomes containing ethanol for skin delivery of temoporfin: characterization and in vitro penetration studies

scientific article

Drug delivery strategies for poorly water-soluble drugs

scientific article published on July 2007

Drug delivery strategies for poorly water-soluble drugs: the industrial perspective ⬇️

scientific article published on 06 September 2011

Efficacy of temoporfin-loaded invasomes in the photodynamic therapy in human epidermoid and colorectal tumour cell lines ⬇️

scientific article published on July 27, 2010

Efficiency of cytoplasmic delivery by non-cationic liposomes to cells in vitro: a confocal laser scanning microscopy study

scientific article

Efficient gene delivery with serum into human cancer cells using targeted anionic liposomes

scientific article published on January 2004

Elastic vesicles for transdermal drug delivery of hydrophilic drugs: a comparison of important physicochemical characteristics of different vesicle types.

scientific article published on August 2012

Electron microscopy and theoretical modeling of cochleates

scientific article published on 28 October 2014

Electrostatic model for mixed cationic-zwitterionic lipid bilayers

scientific article published in May 2006

Encapsulation of Ferritin, Ribosomes, and Ribo-Peptidic Complexes Inside Liposomes: Insights Into the Origin of Metabolism

scientific article published on 19 October 2012

Encapsulation of gadobutrol in AVE-based liposomal carriers for MR detectability

scientific article published in May 2004

Endoglin based in vivo near-infrared fluorescence imaging of tumor models in mice using activatable liposomes

scientific article published on 13 March 2018

Fast high-throughput screening of temoporfin-loaded liposomal formulations prepared by ethanol injection method

scientific article

Flow cytometry as a new approach to investigate drug transfer between lipid particles

scientific article published in April 2010

Fluorescence-quenching of a liposomal-encapsulated near-infrared fluorophore as a tool for in vivo optical imaging

scientific article published on 5 January 2015

Fluorescent liposomes as contrast agents for in vivo optical imaging of edemas in mice

scientific article

Generation of immunoliposomes using recombinant single-chain Fv fragments bound to Ni-NTA-liposomes

scientific article published in August 2005

Human Skin Permeation of Neutral Species and Ionic Species: Extended Linear Free Energy Relationship Analyses ⬇️

scientific article published on March 13, 2012

In vitro characterization of binding and stability of single-chain Fv Ni-NTA-liposomes

scientific article published on September 2006

In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes

scientific article published on 5 May 2014

Influence of massage and occlusion on the ex vivo skin penetration of rigid liposomes and invasomes

scientific article

Interaction of lipid nanoparticles with human epidermis and an organotypic cell culture model

scientific article published on 25 August 2007

Interactions of cyclosporines with lipid membranes as studied by solid-state nuclear magnetic resonance spectroscopy and high-sensitivity titration calorimetry

scientific article published in March 2002

Interfacial concentrations of chloride and bromide in zwitterionic micelles with opposite dipoles: experimental determination by chemical trapping and a theoretical description

scientific article published on 21 January 2012

Investigations of the influence of liposome composition on vesicle stability and drug transfer in human plasma: a transfer study.

scientific article published on 18 October 2016

Kinetics of Aspartic Acid Isomerization and Enantiomerization in Model Aspartyl Tripeptides under Forced Conditions ⬇️

scientific article published on October 1, 2010

LeciPlex, invasomes, and liposomes: A skin penetration study

scientific article published on 19 May 2015

Lecithin and PLGA-based self-assembled nanocomposite, Lecithmer: preparation, characterization, and pharmacokinetic/pharmacodynamic evaluation

scientific article published on July 2016

Lecithin-based novel cationic nanocarriers (LeciPlex) I: fabrication, characterization and evaluation

scientific article

Lecithin-based novel cationic nanocarriers (Leciplex) II: improving therapeutic efficacy of quercetin on oral administration

scientific article published on 20 April 2011

Linear Free Energy Relationship Analysis of Retention Factors in Cerasome Electrokinetic Chromatography Intended for Predicting Drug Skin Permeation ⬇️

scientific article published on March 31, 2011

Lipid Architectonics for Superior Oral Bioavailability of Nelfinavir Mesylate: Comparative in vitro and in vivo Assessment

scientific article published on 12 September 2018

Lipid Colloidal Carriers for Improvement of Anticancer Activity of Orally Delivered Quercetin: Formulation, Characterization and Establishing <I>In Vitro–In Vivo</I> Advantage

scientific article published on July 1, 2013

Lipophilic drug transfer between liposomal and biological membranes: what does it mean for parenteral and oral drug delivery?

scientific article published on January 2006

Lipophilicity and Its Relationship with Passive Drug Permeation ⬇️

scientific article published on October 30, 2010

Lipophilicity measurement of drugs by reversed phase HPLC over Wide pH range using an alkaline-resistant silica-based stationary phase, XBridge Shield RP(18).

scientific article published in October 2008

Liposomal Encapsulation of a Near‐Infrared Fluorophore Enhances Fluorescence Quenching and Reliable Whole Body Optical Imaging Upon Activation In Vivo ⬇️

scientific article published on May 6, 2013

Liposomes in topical photodynamic therapy ⬇️

scientific article published on June 25, 2012

Micro-spherical cochleate composites: method development for monodispersed cochleate system

scientific article published on 12 May 2016

Micro-structured smart hydrogels with enhanced protein loading and release efficiency.

scientific article published on 12 November 2009

Modeling the Release Kinetics of Poorly Water-Soluble Drug Molecules from Liposomal Nanocarriers ⬇️

scientific article published on 07 June 2011

New Insights into the Growth and Transformation of Vesicles: A Free-Flow Electrophoresis Study

scientific article published on 04 September 2015

Non-invasive depth profile imaging of the stratum corneum using confocal Raman microscopy: first insights into the method

scientific article published on 10 June 2013

Novel Lipid Nanotubes in Dispersions of DMPC

Novel insights into appropriate encapsulation methods for bioactive compounds into polymers: a study with peptides and HDAC inhibitors

scientific article published on 21 August 2013

Permeability changes in response to NONOate and NONOate prodrug derived nitric oxide in a blood-brain barrier model formed by primary porcine endothelial cells

scientific article published on 2 February 2008

Pharmacokinetics of temoporfin-loaded liposome formulations: Correlation of liposome and temoporfin blood concentration ⬇️

scientific article published on January 11, 2013

Photodynamic killing of Enterococcus faecalis in dentinal tubules using mTHPC incorporated in liposomes and invasomes

scientific article published on 21 June 2014

Physical Routes to Primitive Cells: An Experimental Model Based on the Spontaneous Entrapment of Enzymes inside Micrometer-Sized Liposomes.

scientific article

Physicochemical characterization of solid dispersions of three antiepileptic drugs prepared by solvent evaporation method

scientific article published on 01 May 2007

Polymersomes containing iron sulfide (FeS) as primordial cell model : for the investigation of energy providing redox reactions.

scientific article published on 10 August 2010

Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases

scientific article published on 23 February 2016

Preservation of liquid drug preparations for oral administration.

scientific article published in January 2010

Quantitative In Vitro Assessment of Liposome Stability and Drug Transfer Employing Asymmetrical Flow Field-Flow Fractionation (AF4).

scientific article published on 23 November 2015

Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors

scientific article published on 15 October 2020

Selective partitioning of cholesterol and a model drug into liposomes of varying size

scientific article published on 16 April 2012

Skin delivery of ferulic acid from different vesicular systems

scientific article published on October 1, 2010

Skin penetration and deposition of carboxyfluorescein and temoporfin from different lipid vesicular systems: In vitro study with finite and infinite dosage application ⬇️

scientific article published on February 21, 2011

Spontaneous Protein Crowding in Liposomes: A New Vista for the Origin of Cellular Metabolism

scientific article published on 01 September 2010

Spontaneous crowding of ribosomes and proteins inside vesicles: a possible mechanism for the origin of cell metabolism.

scientific article published on 9 August 2011

Spontaneous encapsulation and concentration of biological macromolecules in liposomes: an intriguing phenomenon and its relevance in origins of life

scientific article

Stability evaluation of temoporfin-loaded liposomal gels for topical application.

scientific article published in March 2010

Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons

scientific article published on 12 May 2006

Study of pK values and effective dielectric constants of ionizable residues in pentapeptides and in staphylococcal nuclease (SNase) using a mean-field approach

scientific article published on 7 April 2014

Supercooled smectic nanoparticles: influence of the matrix composition and in vitro cytotoxicity

scientific article

Surface charged temoporfin-loaded flexible vesicles: in vitro skin penetration studies and stability

scientific article

Sustained-release injectables formed in situ and their potential use for veterinary products

scientific article

Targeting the Tumor Microenvironment with Fluorescence-Activatable Bispecific Endoglin/Fibroblast Activation Protein Targeting Liposomes

scientific article published on 17 April 2020

Temoporfin-loaded invasomes: development, characterization and in vitro skin penetration studies

scientific article

Temoporfin-loaded liposomal gels: viscoelastic properties and in vitro skin penetration.

scientific article published on 24 February 2009

Temoporfin-loaded liposomes: physicochemical characterization

scientific article

The physical state of lipid nanoparticles influences their effect on in vitro cell viability ⬇️

scientific article published on March 31, 2011

Tip-enhanced Raman scattering for tracking of invasomes in the stratum corneum

scientific article

Topical application of temoporfin-loaded invasomes for photodynamic therapy of subcutaneously implanted tumours in mice: a pilot study

scientific article

Transdermal delivery from liposomal formulations - Evolution of the technology over the last three decades

scientific article published on 10 September 2016

Transfer mechanism of temoporfin between liposomal membranes ⬇️

scientific article published on March 30, 2011

Transfer of a lipophilic drug (temoporfin) between small unilamellar liposomes and human plasma proteins: influence of membrane composition on vesicle integrity and release characteristics ⬇️

scientific article published on April 16, 2013

Transfer of lipophilic drugs between liposomal membranes and biological interfaces: consequences for drug delivery

scientific article

Understanding cochleate formation: insights into structural development

scientific article

Using a modified shepards method for optimization of a nanoparticulate cyclosporine a formulation prepared by a static mixer technique

scientific article published on 01 February 2008

Utilization of liposomes for studying drug transfer and uptake

scientific article published on 01 January 2010

Vesicle aggregates as a model for primitive cellular assemblies.

scientific article published on 20 July 2017

Wheat Germ Agglutinin Modified Liposomes for the Photodynamic Inactivation of Bacteria† ⬇️

scientific article published on September 16, 2011

[FeFe]-hydrogenase models assembled into vesicular structures.

scientific article published on 5 September 2013

[Non-viral gene transfer medicinal products. Therapy with synthetic vectors]

scientific article published on 01 May 2011

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