List of works - Darren M Griffith

A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity.

scientific article published on 12 October 2009

A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity

scientific article published on 29 March 2013

A novel ruthenium nitrosyl complex which also contains a free NO-donor moiety

Au(III) and Pt(II) Complexes of a Novel and Versatile 1,4-Disubstituted 1,2,3-Triazole-Based Ligand Possessing Diverse Secondary and Tertiary Coordinating Groups

scientific article published on 07 September 2018

Current and potential applications of bismuth-based drugs.

scientific article published on 23 September 2014

Development of a novel carboplatin like cytoplasmic trackable near infrared fluorophore conjugate via strain-promoted azide alkyne cycloaddition.

scientific article published on 21 February 2018

Ground and excited state communication within a ruthenium containing benzimidazole metallopolymer

scientific article published on 14 March 2011

Hydroxamic Acids − An Intriguing Family of Enzyme Inhibitors and Biomedical Ligands

Hydroxamic Acids: Chemistry, Bioactivity, and Solutionand Solid-Phase Synthesis

Monohydroxamic acids and bridging dihydroxamic acids as chelators to ruthenium(III) and as nitric oxide donors: syntheses, speciation studies and nitric oxide releasing investigations

scientific article published in January 2008

Ni(II), Pd(II), and Pt(II) Complexes of the Hedgehog Pathway Inhibitor GANT61-D

scientific article published on 15 November 2019

Novel Improved Synthesis of HSP70 Inhibitor, Pifithrin-μ. In Vitro Synergy Quantification of Pifithrin-μ Combined with Pt Drugs in Prostate and Colorectal Cancer Cells.

scientific article published on 21 July 2016

Novel antimony(iii) hydroxamic acid complexes as potential anti-leishmanial agents

scientific article published on 01 May 2018

Novel class of Bi(iii) hydroxamato complexes: synthesis, urease inhibitory activity and activity against H. pylori.

scientific article published on 17 June 2016

Novel platinum(II) ammine hydroxamate and hydroximate complexes and the platinum-assisted hydrolysis of hydroxamic acids

scientific article

Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity

scientific article published on 14 March 2011

Platinum(iv) oxaliplatin-peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells.

scientific article

Ruthenium(III) dimethyl sulfoxide pyridinehydroxamic acid complexes as potential antimetastatic agents: synthesis, characterisation and in vitro pharmacological evaluation

scientific article published on May 2008

Suberoylanilide hydroxamic acid, a potent histone deacetylase inhibitor; its X-ray crystal structure and solid state and solution studies of its Zn(II), Ni(II), Cu(II) and Fe(III) complexes

scientific article published on 22 March 2011

Synthesis and characterisation of Co(iii) complexes of N-formyl hydroxylamines and antibacterial activity of a Co(iii) peptide deformylase inhibitor complex

scientific article published on 29 April 2020

Synthesis, characterisation and speciation studies of heterobimetallic pyridinehydroxamate-bridged Pt(II)/M(II) complexes (M = Cu, Ni, Zn). Crystal structure of a novel heterobimetallic 3-pyridinehydroxamate-bridged Pt(II)/Cu(II) wave-like coordinat

scientific article published on 4 May 2005

The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum

scientific article published on 01 November 2012

The reduction of platinum(IV) and palladium(IV) ions by 2,6-pyridinedihydroxamic acid

scientific article

Valuable insight into the anticancer activity of the platinum-histone deacetylase inhibitor conjugate, cis-[Pt(NH3)2malSAHA-2H)].

scientific article published on 25 May 2012

List of works by Darren M Griffith

A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity.

A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity

A novel ruthenium nitrosyl complex which also contains a free NO-donor moiety

Au(III) and Pt(II) Complexes of a Novel and Versatile 1,4-Disubstituted 1,2,3-Triazole-Based Ligand Possessing Diverse Secondary and Tertiary Coordinating Groups

Current and potential applications of bismuth-based drugs.

Development of a novel carboplatin like cytoplasmic trackable near infrared fluorophore conjugate via strain-promoted azide alkyne cycloaddition.

Ground and excited state communication within a ruthenium containing benzimidazole metallopolymer

Hydroxamic Acids − An Intriguing Family of Enzyme Inhibitors and Biomedical Ligands

Hydroxamic Acids: Chemistry, Bioactivity, and Solutionand Solid-Phase Synthesis

Monohydroxamic acids and bridging dihydroxamic acids as chelators to ruthenium(III) and as nitric oxide donors: syntheses, speciation studies and nitric oxide releasing investigations

Ni(II), Pd(II), and Pt(II) Complexes of the Hedgehog Pathway Inhibitor GANT61-D

Novel Improved Synthesis of HSP70 Inhibitor, Pifithrin-μ. In Vitro Synergy Quantification of Pifithrin-μ Combined with Pt Drugs in Prostate and Colorectal Cancer Cells.

Novel antimony(iii) hydroxamic acid complexes as potential anti-leishmanial agents

Novel class of Bi(iii) hydroxamato complexes: synthesis, urease inhibitory activity and activity against H. pylori.

Novel platinum(II) ammine hydroxamate and hydroximate complexes and the platinum-assisted hydrolysis of hydroxamic acids

Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity

Platinum(iv) oxaliplatin-peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells.

Ruthenium(III) dimethyl sulfoxide pyridinehydroxamic acid complexes as potential antimetastatic agents: synthesis, characterisation and in vitro pharmacological evaluation

Suberoylanilide hydroxamic acid, a potent histone deacetylase inhibitor; its X-ray crystal structure and solid state and solution studies of its Zn(II), Ni(II), Cu(II) and Fe(III) complexes

Synthesis and characterisation of Co(iii) complexes of N-formyl hydroxylamines and antibacterial activity of a Co(iii) peptide deformylase inhibitor complex

Synthesis, characterisation and speciation studies of heterobimetallic pyridinehydroxamate-bridged Pt(II)/M(II) complexes (M = Cu, Ni, Zn). Crystal structure of a novel heterobimetallic 3-pyridinehydroxamate-bridged Pt(II)/Cu(II) wave-like coordinat

The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum

The reduction of platinum(IV) and palladium(IV) ions by 2,6-pyridinedihydroxamic acid

Valuable insight into the anticancer activity of the platinum-histone deacetylase inhibitor conjugate, cis-[Pt(NH3)2malSAHA-2H)].