List of works by Jeffrey H Miner

A chemotactic peptide from laminin alpha 5 functions as a regulator of inflammatory immune responses via TNF alpha-mediated signaling.

scientific article published on February 2005

A deletion in the N-terminal polymerizing domain of laminin β2 is a new mouse model of chronic nephrotic syndrome

scientific article published on 20 February 2020

A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes

scientific article published on June 2016

A hypomorphic mutation in the mouse laminin alpha5 gene causes polycystic kidney disease

scientific article

A missense LAMB2 mutation causes congenital nephrotic syndrome by impairing laminin secretion

scientific article published on 21 April 2011

A molecular look at the glomerular barrier

scientific article published on 01 January 2003

A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers

scientific article

A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development

scientific article published on August 2002

A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder

scientific article published on 21 May 2020

A new function for parietal epithelial cells: a second glomerular barrier

scientific article

A potent HIV protease inhibitor, darunavir, does not inhibit ZMPSTE24 or lead to an accumulation of farnesyl-prelamin A in cells

scientific article published on 28 January 2008

A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis

scientific article published on 22 February 2016

A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis

scientific article published on March 2016

A simplified laminin nomenclature

scientific article

A site on laminin alpha 5, AQARSAASKVKVSMKF, induces inflammatory cell production of matrix metalloproteinase-9 and chemotaxis

scientific article published in July 2003

Ablation of developing podocytes disrupts cellular interactions and nephrogenesis both inside and outside the glomerulus

scientific article published on 08 October 2008

Abnormalities in neural crest cell migration in laminin alpha5 mutant mice

scientific journal article

Activation of NFAT signaling in podocytes causes glomerulosclerosis

scientific article

Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome

scientific article

Albumin contributes to kidney disease progression in Alport syndrome

scientific article published on 04 May 2016

Albumin-associated free fatty acids induce macropinocytosis in podocytes

scientific article published on 27 April 2015

Albuminuria, wherefore art thou?

scientific article published on 25 February 2009

Alport Syndrome Therapeutics: Ready for Prime-Time Players

scientific article published on 24 August 2019

Alport syndrome and Pierson syndrome: Diseases of the glomerular basement membrane.

scientific article published on 16 April 2018

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy.

scientific article

B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement.

scientific article published on 2 November 2017

Basement membrane ligands initiate distinct signalling networks to direct cell shape

scientific article published on 06 March 2020

Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity

scientific article published on 31 January 2008

Beta1-integrins are critical for cerebellar granule cell precursor proliferation

scientific journal article

Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

scientific article published on 20 April 2006

Biophysical properties of normal and diseased renal glomeruli

scientific article

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

scientific article

Breaking down the barrier: evidence against a role for heparan sulfate in glomerular permselectivity

scientific article published on 14 February 2007

Building the glomerulus: a matricentric view

scientific article

CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility

scientific article (publication date: 23 May 2003)

CNS Neurons Deposit Laminin α5 to Stabilize Synapses

scientific article published in October 2017

Clinical trial recommendations for potential Alport syndrome therapies

scientific article published on 06 April 2020

Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development ⬇️

scientific article published on April 15, 2003

Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation

scientific journal article

Coordinate control of axon defasciculation and myelination by laminin-2 and -8.

scientific article

Coordinate integrin and c-Met signaling regulate Wnt gene expression during epithelial morphogenesis

scientific article published on 28 January 2009

Correction: Nanoscale protein architecture of the kidney glomerular basement membrane.

scientific article published on 11 October 2013

Correction: Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity.

scientific article published on 29 July 2008

Correction: Role of the Polarity Protein Scribble for Podocyte Differentiation and Maintenance.

scientific article published on 3 January 2014

DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis

scientific article

Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

scientific article published on 22 October 2021

Defining kidney biology to understand renal disease

scientific article published on 26 December 2013

Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing.

scientific article published on 23 March 2018

Differential expression of parietal epithelial cell and podocyte extracellular matrix proteins in focal segmental glomerulosclerosis and diabetic nephropathy

scientific article published on 21 October 2019

Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome

scientific article published on 16 December 2020

Discs large 1 controls daughter-cell polarity after cytokinesis in vertebrate morphogenesis

article published in the Proceedings of the National Academy of Sciences of the United States of America

Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter

scientific article

Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity

scientific article published in July 2007

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome ⬇️

scientific article published on October 1, 1995

Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen

scientific article published on 19 October 2005

Domain IV of mouse laminin beta1 and beta2 chains

scientific article published in January 2002

Dual lineage tracing shows that glomerular parietal epithelial cells can transdifferentiate toward the adult podocyte fate

scientific article published on 29 March 2019

Dystroglycan does not contribute significantly to kidney development or function, in health or after injury

scientific article

Endothelial cell-specific collagen type IV-α3 expression does not rescue Alport syndrome in Col4a3-/- mice

scientific article published on 06 February 2019

Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling

scientific article

Epithelial laminin alpha5 is necessary for distal epithelial cell maturation, VEGF production, and alveolization in the developing murine lung.

scientific article published in June 2005

Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques

scientific article published in June 2003

Expression of type IV collagen α1(IV)–α6(IV) polypeptides in normal and developing human kidney and in renal cell carcinomas and oncocytomas

scientific article published on 01 July 1997

Fatty acid transport protein 1 can compensate for fatty acid transport protein 4 in the developing mouse epidermis

scientific article

Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase

scientific article

Fatty acid transport protein 4 is dispensable for intestinal lipid absorption in mice

scientific journal article

Fatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols

scientific article published on 13 September 2019

Fatty acid transport protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fibroblasts

scientific journal article

Feasibility of repairing glomerular basement membrane defects in Alport syndrome

scientific article

Focusing on the glomerular slit diaphragm: podocin enters the picture

scientific article

Forced expression of laminin beta1 in podocytes prevents nephrotic syndrome in mice lacking laminin beta2, a model for Pierson syndrome

scientific article

Functional assessment of a novel COL4A5 splice region variant and immunostaining of plucked hair follicles as an alternative method of diagnosis in X-linked Alport syndrome

scientific article published on 24 December 2016

Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries

scientific article

Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney

scientific journal article

Glomerular Mesangial Cell Recruitment and Function Requires the Co-Receptor Neuropilin-1.

scientific article

Glomerular basement membrane and related glomerular disease

scientific article

Glomerular basement membrane composition and the filtration barrier

scientific article published on 15 February 2011

Glomerular filtration is normal in the absence of both agrin and perlecan-heparan sulfate from the glomerular basement membrane

scientific article published on 14 January 2009

Glomerular filtration: the charge debate charges ahead

scientific article published on 01 August 2008

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

scientific article

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

article published in 2003

Histopathology, ultrastructure, and clinical phenotypes in thin glomerular basement membrane disease variants

scientific article published on 01 August 2002

Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.

scientific article

Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy

scientific article

Identification of the binding site for the Lutheran blood group glycoprotein on laminin alpha 5 through expression of chimeric laminin chains in vivo

scientific article (publication date: 22 November 2002)

Impaired glomerular maturation and lack of VEGF165b in Denys-Drash syndrome

scientific article published on 31 January 2007

Increased progerin expression associated with unusual LMNA mutations causes severe progeroid syndromes.

scientific article

Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy

scientific article published on 17 August 2017

Intravital and Kidney Slice Imaging of Podocyte Membrane Dynamics

scientific article published on April 2016

Keratinocyte-specific expression of fatty acid transport protein 4 rescues the wrinkle-free phenotype in Slc27a4/Fatp4 mutant mice

scientific journal article

Keratinocyte-targeted expression of human laminin γ2 rescues skin blistering and early lethality of laminin γ2 deficient mice

scientific article

Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

scientific article published on 23 December 2019

Knockout of aminopeptidase A in mice causes functional alterations and morphological glomerular basement membrane changes in the kidneys

scientific article published on 11 December 2020

Laminets: laminin- and netrin-related genes expressed in distinct neuronal subsets

scientific article published in March 2002

Laminin alpha 5 influences the architecture of the mouse small intestine mucosa

scientific article published on 15 July 2008

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung

scientific journal article

Laminin alpha5 chain is required for intestinal smooth muscle development

scientific journal article

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling

scientific article

Laminin alpha5 is required for dental epithelium growth and polarity and the development of tooth bud and shape

scientific journal article

Laminin compensation in collagen alpha3(IV) knockout (Alport) glomeruli contributes to permeability defects

scientific article published on 15 August 2007

Laminin functions in tissue morphogenesis.

scientific article published in January 2004

Laminin α1 regulates age-related mesangial cell proliferation and mesangial matrix accumulation through the TGF-β pathway

scientific article

Laminin α5 guides tissue patterning and organogenesis

scientific article published on 17 October 2012

Laminin β2 gene missense mutation produces endoplasmic reticulum stress in podocytes

scientific article published on 30 May 2013

Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells

scientific article

Laminin-10 is crucial for hair morphogenesis ⬇️

scientific article published on May 15, 2003

Laminin-521 Protein Therapy for Glomerular Basement Membrane and Podocyte Abnormalities in a Model of Pierson Syndrome.

scientific article published on 22 February 2018

Laminins alpha2 and alpha4 in pancreatic acinar basement membranes are required for basal receptor localization

scientific article published on February 2004

Laminins and their roles in mammals

scientific article published on May 2008

Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction

scientific article published on 15 September 2008

Life without nephrin: it's for the birds

scientific article published on 2 February 2012

Linear ion-trap MSn with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis

scientific article published on 2 February 2017

Loss of Endothelial Laminin α5 Exacerbates Hemorrhagic Brain Injury

scientific article published on 29 January 2019

Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.

scientific article

Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS.

scientific article

Maintenance of glomerular filtration barrier integrity requires laminin alpha5.

scientific article

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues

scientific article published on 08 February 2020

Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions

scientific article published on 10 May 2021

Mesencephalic Astrocyte-Derived Neurotrophic Factor as a Urine Biomarker for Endoplasmic Reticulum Stress-Related Kidney Diseases.

scientific article published on 3 March 2016

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function

scientific article published on 5 May 2006

Mural cell-derived laminin-α5 plays a detrimental role in ischemic stroke

scientific article published on 18 February 2019

Muscular dystrophy meets protein biochemistry, the mother of invention

scientific article published on 20 February 2017

Mutations in LAMB2 Are Associated With Albuminuria and Optic Nerve Hypoplasia With Hypopituitarism

scientific article published on 01 March 2020

Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope

scientific article published on 22 November 2018

Nanoscale protein architecture of the kidney glomerular basement membrane.

scientific article published on 08 October 2013

Neonatal Fc receptor promotes immune complex-mediated glomerular disease

scientific article published on 19 December 2013

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity

scientific article

Of laminins and delamination in Alport syndrome

scientific article published on 01 March 2003

Opposing Roles of Dendritic Cell Subsets in Experimental GN.

scientific article

Organogenesis of the kidney glomerulus: focus on the glomerular basement membrane

scientific article published on April 2011

Parietal epithelial cell differentiation to a podocyte fate in the aged mouse kidney

scientific article published on 28 August 2020

Partial rescue of glomerular laminin alpha5 mutations by wild-type endothelia produce hybrid glomeruli.

scientific article

Pathogenesis of nonimmune glomerulopathies

scientific article

Pathogenicity of a Human Laminin β2 Mutation Revealed in Models of Alport Syndrome.

scientific article published on 20 December 2017

Pathology vs. molecular genetics: (re)defining the spectrum of Alport syndrome

scientific article

Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules

scientific article published on 28 February 2017

Peroxidasin-mediated bromine enrichment of basement membranes

scientific article published on 22 June 2020

Podocyte biology in 2015: New insights into the mechanisms of podocyte health.

scientific article published on 21 December 2015

Podocyte-derived BMP7 is critical for nephron development

scientific article published on 15 October 2008

Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease

scientific article published on 05 September 2008

Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

scientific article

Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases

scientific article published on 2 May 2017

Podocytes use FcRn to clear IgG from the glomerular basement membrane

scholarly article

Preface

Preface

Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier

scientific journal article

Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers

scientific article published on 9 January 2013

Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome

scientific article

Rac1 activation in podocytes induces rapid foot process effacement and proteinuria

scientific article published on 23 September 2013

Re-characterization of the Glomerulopathy in CD2AP Deficient Mice by High-Resolution Helium Ion Scanning Microscopy.

scientific article published on 16 August 2017

Red cell traverse through thin glomerular basement membrane

scientific article published on 01 February 2002

Requirement for basement membrane laminin α5 during urethral and external genital development

scientific article published on 18 May 2016

Requirement of fatty acid transport protein 4 for development, maturation, and function of sebaceous glands in a mouse model of ichthyosis prematurity syndrome

scientific article published on 27 December 2012

Restrictive dermopathy and ZMPSTE24 mutations in Mennonites: Evidence for allelic heterogeneity.

scientific article published in August 2010

Review: Lutheran/B-CAM: a laminin receptor on red blood cells and in various tissues

scientific article

Revisiting the glomerular charge barrier in the molecular era.

scientific article published on July 2008

Role of COL4A1 in small-vessel disease and hemorrhagic stroke

scientific article published in April 2006

Role of fatty acid transporters in epidermis: Implications for health and disease

scientific article published on April 2011

Role of the polarity protein Scribble for podocyte differentiation and maintenance

scientific article

Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development

scientific article published on 09 May 2013

Stem cell therapy for Alport syndrome: the hope beyond the hype

scientific article published on 25 December 2008

Super-resolution Imaging of the Kidney Glomerulus in Health and Disease Conditions

article

Synaptopodin Is Dispensable for Normal Podocyte Homeostasis but Is Protective in the Context of Acute Podocyte Injury

scientific article published on 16 September 2020

Systematic Analysis of Splice-Site-Creating Mutations in Cancer.

scientific article published in April 2018

TGF-beta1 induces aberrant laminin chain and collagen type IV isotype expression in the glomerular basement membrane

scientific article published on 01 January 2003

The 2014 International Workshop on Alport Syndrome.

scientific article published on 2 July 2014

The LG1-3 tandem of laminin alpha5 harbors the binding sites of Lutheran/basal cell adhesion molecule and alpha3beta1/alpha6beta1 integrins

scientific article

The Pax3-Cre transgene exhibits a rostrocaudal gradient of expression in the skeletal muscle lineage

scientific article published on January 2009

The amphibian kidney's filtration barrier: where is the glomerular basement membrane?

scientific article published in August 2009

The biodistribution of [153Gd]Gd-labeled magnetic resonance contrast agents in a transgenic mouse model of renal failure differs greatly from control mice.

scientific article

The enigmatic parietal epithelial cell is finally getting noticed: a review

scientific article published on 21 October 2009

The expression and function of fatty acid transport protein-2 and -4 in the murine placenta

scientific article

The glomerular basement membrane

scientific article published on 05 March 2012

The glomerular basement membrane as a barrier to albumin

scientific article

The importance of clinician, patient and researcher collaborations in Alport syndrome

scientific article published on 01 May 2019

The lutheran/basal cell adhesion molecule promotes tumor cell migration by modulating integrin-mediated cell attachment to laminin-511 protein.

scientific article published on 13 September 2013

Three-dimensional electron microscopy reveals the evolution of glomerular barrier injury.

scientific article

Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation

scientific article

Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

scientific article

Transgenic isolation of skeletal muscle and kidney defects in laminin beta2 mutant mice: implications for Pierson syndrome

scientific article

Transient expression of laminin alpha1 chain in regenerating murine liver: restricted localization of laminin chains and nidogen-1.

scientific article published on April 2005

Type IV collagen and diabetic kidney disease

scientific article published on 01 January 2020

Ultrastructural Characterization of the Glomerulopathy in Alport Mice by Helium Ion Scanning Microscopy (HIM).

scientific article published on 15 September 2017

Update on the glomerular filtration barrier

scientific article (publication date: May 2009)

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.

scientific article published on 25 January 2006

What Is the Glomerular Ultrafiltration Barrier?

scientific article

Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival

scientific article

trans-Activation and repression properties of the novel nonsteroid glucocorticoid receptor ligand 2,5-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and its four stereoisomers

scientific article (publication date: August 2002)

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