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List of works by Ryszard Bugno

-Skatyltryptamines-Dual 5-HTR/DR Ligands with Antipsychotic and Procognitive Potential

scientific article published on 29 July 2021

2-Aminoimidazole-based antagonists of the 5-HT6 receptor - A new concept in aminergic GPCR ligand design

scientific article published on 05 June 2019

5-HT1A receptor ligands and their therapeutic applications: review of new patents

scientific article published on 07 September 2018

A study on application of impregnated synthetic peptide TLC stationary phases for the screening of 5-HT1A ligands. Part 2.

scientific article

Comparison of an Addictive Potential of μ-Opioid Receptor Agonists with G Protein Bias: Behavioral and Molecular Modeling Studies

scientific article published on 27 December 2021

Conformational restriction in novel NAN-190 and MP3022 analogs and their 5-HT(1A) receptor activity

scientific article published on 01 September 2006

Effects of ketamine optical isomers, psilocybin, psilocin and norpsilocin on time estimation and cognition in rats

scientific article published in June 2022

Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT7 receptor low-basicity agonists, potential neuropathic painkillers

scientific article published on 11 March 2019

Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine

scientific article published on 08 December 2019

Halogen bonding enhances activity in a series of dual 5-HT6/D2 ligands designed in a hybrid bioisostere generation/virtual screening protocol

scholarly article in RSC Advances, vol. 6 no. 60, 2016

Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux

scientific article published on 17 February 2017

Introduction of a new complex imide system into the structure of LCAPs. The synthesis and a 5-HT1A, 5-HT2A and D2 receptor binding study.

scientific article published in November 2004

Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2

scientific article published on 21 January 2021

Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol

scientific article

Modification of the structure of 4, 6-disubstituted 2-(4-alkyl-1-piperazinyl)pyridines: synthesis and their 5-HT2A receptor activity.

scientific article published in April 2003

Molecular Modeling of µ Opioid Receptor Ligands with Various Functional Properties: PZM21, SR-17018, Morphine, and Fentanyl-Simulated Interaction Patterns Confronted with Experimental Data

scientific article published on 12 October 2020

New imide 5-HT1A receptor ligands - modification of terminal fragment geometry

scientific article published on 28 February 2004

Novel N-[omega-[4-(2-methoxyphenyl)piperazin-1-yl]-ethyl]pyrid-2(1H)-ones with diversified 5-HT1A receptor activity

scientific article published in November 2002

Novel, flexible, and conformationally defined analogs of gepirone: synthesis and 5-HT1A, 5-HT2A, and D2 receptor activity.

scientific article published in February 2005

Oncotoxic Properties of Serotonin Transporter Inhibitors and 5-HT Receptor Ligands

scientific article published on 20 October 2018

Pharmaceuticals and personal care products in the urban groundwater – preliminary monitoring (case study: Kraków, Southern Poland)

scientific article published on 3 March 2021

Rationally designed N-phenylsulfonylindoles as a tool for the analysis of the non-basic 5-HT<sub>6</sub>R ligands binding mode

scientific article published on 09 October 2020

SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling

scientific article

Serotonin type 5A receptor antagonists inhibit D-lysergic acid diethylamide discriminatory cue in rats

scientific article published on 27 August 2019

Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT and 5-HT Receptor Antagonist with Antipsychotic and Procognitive Properties

scientific article published on 23 September 2021

Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.

scientific article published on 2 November 2005

Synthesis, in vitro and in vivo 5-HT1A/5-HT2A serotonin receptor activity of new hybrid 1,2,3,4-tetrahydro-gamma-carbolines with 1-(2-methoxyphenyl)piperazine moiety.

scientific article

The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines

scientific article published on 22 August 2007

Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties

scientific article published on 07 November 2019

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