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List of works by Gabriella Leonarduzzi

4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis.

scientific article

4-Hydroxynonenal signalling to apoptosis in isolated rat hepatocytes: the role of PKC-delta.

scientific article published on 4 November 2005

4-Hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases.

scientific article

4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest.

scientific article published on July 2008

Activation of the mitochondrial pathway of apoptosis by oxysterols

scientific article published on January 2007

Alternate-day fasting protects the rat heart against age-induced inflammation and fibrosis by inhibiting oxidative damage and NF-kB activation.

scientific article

Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways ⬇️

scientific article published on June 29, 2011

Calorie restriction protects against age-related rat aorta sclerosis

scientific article published on 08 September 2005

Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation

scientific article published on 16 September 2016

Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry.

scientific article published on January 2009

Cholesterol oxidation products in the vascular remodeling due to atherosclerosis.

scientific article published on 25 February 2009

Detection of cytochrome P4503A (CYP3A) in human hepatic stellate cells.

scientific article published on September 1997

Dietary lipids and their oxidized products in Alzheimer's disease.

scientific article published on 31 August 2011

Early involvement of ROS overproduction in apoptosis induced by 7-ketocholesterol.

scientific article published on March 2006

Enrichment with arachidonic acid increases the sensitivity of hepatoma cells to the cytotoxic effects of oxidative stress

scientific article published on 01 February 1995

Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line.

scientific article

Hepatocellular metabolism of 4-hydroxy-2,3-nonenal is impaired in conditions of chronic cholestasis

scientific article published on 01 September 1995

Induction of Procollagen Type I Gene Expression and Synthesis in Human Hepatic Stellate Cells by 4-Hydroxy-2,3-Nonenal and Other 4-Hydroxy-2,3-Alkenals Is Related to Their Molecular Structure

article

Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis.

scientific article published on 02 October 2011

Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets.

scientific article published on March 2013

Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol.

scientific article

Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.

scientific article published on 5 April 2011

Lipid peroxidation and inflammatory molecules as markers of coronary artery disease

scientific article published on 01 January 2007

Lipid peroxidation in hepatoma cell lines and their sensitivity to 4-hydroxynonenal

scientific article published on 01 January 1993

Liver AP-1 activation due to carbon tetrachloride is potentiated by 1,2-dibromoethane but is inhibited by alpha-tocopherol or gadolinium chloride

scientific article published on 01 May 1999

Loading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterols

scientific article (publication date: 2014)

Metalloproteinases and metalloproteinase inhibitors in age-related diseases.

scientific article published on January 2014

Modulation of hepatic fibrogenesis by antioxidants.

scientific article

Molecular signaling involved in oxysterol-induced β₁-integrin over-expression in human macrophages.

scientific article published on 5 November 2012

Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells

scientific article published in May 2010

Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells

scientific article published on 9 December 2015

Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid.

scientific article published on December 1996

On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis

scientific article published on 01 January 1996

Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture.

scientific article published on 10 March 2008

Oxidized cholesterol as the driving force behind the development of Alzheimer's disease

scientific article

Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review).

scientific article

Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells

scientific article published on 11 August 2005

Oxysterols and mechanisms of survival signaling.

scientific article published on 23 March 2016

Oxysterols in the pathogenesis of major chronic diseases

scientific article

Phenolic compounds present in Sardinian wine extracts protect against the production of inflammatory cytokines induced by oxysterols in CaCo-2 human enterocyte-like cells.

scientific article published on 9 April 2013

Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage.

scientific article

Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions ⬇️

scientific article published on May 30, 2011

Polyphenol Supplementation as a Complementary Medicinal Approach to Treating Inflammatory Bowel Disease ⬇️

scientific article published on January 1, 2011

Potentiation of amyloid-β peptide neurotoxicity in human dental-pulp neuron-like cells by the membrane lipid peroxidation product 4-hydroxynonenal.

scientific article published on 3 September 2012

Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate.

scientific article published on 27 October 2010

Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability.

scientific article

Role of aldehyde metabolizing enzymes in mediating effects of aldehyde products of lipid peroxidation in liver cells.

scientific article

Signaling kinases modulated by 4-hydroxynonenal.

scientific article

Studies on the antioxidant and free radical scavenging properties of IdB 1016 a new flavanolignan complex

scientific article published on 01 January 1990

Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation

scientific article published on 7 August 2014

Targeting tissue oxidative damage by means of cell signaling modulators: The antioxidant concept revisited ⬇️

scientific article published on August 21, 2010

The core-aldehyde 9-oxononanoyl cholesterol increases the level of transforming growth factor beta1-specific receptors on promonocytic U937 cell membranes.

scientific article published on April 2009

The link between altered cholesterol metabolism and Alzheimer's disease.

scientific article published on July 2012

The role of oxysterols in vascular ageing.

scientific article

The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics

scientific article published in April 2015

Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver

scientific article published on 01 August 1992

Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis

scientific article published on 01 October 1992

Wine consumption and intestinal redox homeostasis

scientific article

c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa

scientific article published on 22 April 2006

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