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List of works by Paolo Cappella

1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.

scientific article published on November 2006

5-(2-Amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors

scientific article published on November 23, 2011

A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds

scientific article published on 28 October 2015

Application of click chemistry conditions for 5-bromo-2'-deoxyuridine determination through Fenton and related reactions.

scientific article

Cell Proliferation Method: Click Chemistry Based on BrdU Coupling for Multiplex Antibody Staining.

scientific article published in April 2015

Cell proliferation method: click chemistry based on BrdU coupling for multiplex antibody staining.

scientific article

Characterization of cyclin B1 expression in human cancer cell lines by a new three-parameter BrdUrd/cyclin B1/DNA analysis

scientific article published on 01 January 1998

CyTOF Mass Cytometry for Click Proliferation Assays.

scientific article published on 5 July 2017

FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients

scientific article

Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors

scientific article

In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.

scientific article published on February 2011

Interpreting cell cycle effects of drugs: the case of melphalan.

scientific article published on 30 September 2005

Measuring the complexity of cell cycle arrest and killing of drugs: kinetics of phase-specific effects induced by taxol

scientific article published on 01 October 1999

Miniaturizing bromodeoxyuridine incorporation enables the usage of flow cytometry for cell cycle analysis of adherent tissue culture cells for high throughput screening.

scientific article published on 8 September 2010

Multiparametric cell cycle analysis by automated microscopy

scientific article published on 14 July 2006

NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies.

scientific article published on 7 February 2012

PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.

scientific article published on July 2006

PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer.

scientific article published on December 2007

Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase

scientific article

Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity

scientific article

Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells

scientific article published on 2 September 2011