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List of works by Uwe Völker

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells

scientific article published in January 2007

2-DE proteome analysis of a proliferating and differentiating human neuronal stem cell line (ReNcell VM).

scientific article published in March 2006

2-DE proteomic profiling of neuronal stem cells

scientific article published on January 2006

3,5-T2 alters murine genes relevant for xenobiotic, steroid, and thyroid hormone metabolism

scientific article published on 22 February 2016

52 Genetic Loci Influencing Myocardial Mass

scientific article

A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio

scientific article (publication date: February 2013)

A comprehensive proteome map of growing Bacillus subtilis cells

scientific article

A description of large-scale metabolomics studies: increasing value by combining metabolomics with genome-wide SNP genotyping and transcriptional profiling

scientific article published on July 10, 2012

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy

scientific article published on 12 July 2013

A genome-wide association study of aging

scientific article

A genome-wide association study of metabolic traits in human urine

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

A genomewide association study of smoking relapse in four European population-based samples

scientific article published on 01 August 2013

A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions

scientific article published on 8 September 2017

A global proteome approach in uric acid stimulated human aortic endothelial cells revealed regulation of multiple major cellular pathways

scientific article

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

A meta-analysis of gene expression signatures of blood pressure and hypertension

scientific article (publication date: March 2015)

A metabolomics and proteomics study of the adaptation of Staphylococcus aureus to glucose starvation

article published in 2011

A network-based approach to visualize prevalence and progression of metabolic syndrome components

scientific article

A new, accurate predictive model for incident hypertension

scientific article published in November 2013

A novel approach to pathogen reduction in platelet concentrates using short-wave ultraviolet light

scientific article published on 4 August 2009

A novel artificial microRNA expressing AAV vector for phospholamban silencing in cardiomyocytes improves Ca2+ uptake into the sarcoplasmic reticulum.

scientific article

A novel assay to assess the effect of pharmaceutical compounds on the differentiation of podocytes

scientific article published on 14 November 2016

A novel engineering tool in the Bacillus subtilis toolbox: inducer-free activation of gene expression by selection-driven promoter decryptification.

scientific article

A peptide resource for the analysis of Staphylococcus aureus in host-pathogen interaction studies

scientific article published on 30 July 2015

A plasmid RK2-based broad-host-range cloning vector useful for transfer of metagenomic libraries to a variety of bacterial species

scientific article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A proteomic perspective of the interplay of Staphylococcus aureus and human alveolar epithelial cells during infection

scientific article published on 2 August 2015

A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome

scientific article

A proteomics workflow for quantitative and time-resolved analysis of adaptation reactions of internalized bacteria

scientific article published on 30 April 2013

A time resolved metabolomics study: the influence of different carbon sources during growth and starvation of Bacillus subtilis

scientific article published on 01 July 2014

A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking

scientific article

ABO blood type B and fucosyltransferase 2 non-secretor status as genetic risk factors for chronic pancreatitis

article published in 2015

Activation of the alternative sigma factor SigB of Staphylococcus aureus following internalization by epithelial cells - an in vivo proteomics perspective

scientific article published on 7 December 2013

Adaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective

scientific article published on 31 March 2014

Adaptation of Bacillus subtilis to growth at low temperature: a combined transcriptomic and proteomic appraisal

scientific article published on 01 March 2006

Adaptive immune response to lipoproteins of Staphylococcus aureus in healthy subjects

scientific article published on 21 June 2016

Advanced tool for characterization of microbial cultures by combining cytomics and proteomics

scientific article published on 30 July 2010

Altered hepatic mRNA expression of immune response and apoptosis-associated genes after acute and chronic psychological stress in mice

scientific article published on 9 July 2009

Altered immune proteome of Staphylococcus aureus under iron-restricted growth conditions

scientific article

Alternative fluorescent labeling strategies for characterizing gram-positive pathogenic bacteria: Flow cytometry supported counting, sorting, and proteome analysis of Staphylococcus aureus retrieved from infected host cells

scientific article

Analysis of Staphylococcus aureus proteins secreted inside infected human epithelial cells

scientific article published on 18 June 2018

Analysis of the expression and function of the σ B -dependent general stress regulon of Bacillus subtilis during slow growth

scientific article published on 01 May 1999

Analysis of the induction of general stress proteins of Bacillus subtilis

scientific journal article

Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium

scientific article

Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome

scientific article published on 01 November 2011

Antibodies Against Potassium Channel Interacting Protein 2 Induce Necrosis in Isolated Rat Cardiomyocytes

scientific article published on 01 April 2014

Antibody responses in furunculosis patients vaccinated with autologous formalin-killed Staphylococcus aureus.

scientific article

Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis.

scientific article published on June 2012

Assembly and function of a spore coat-associated transglutaminase of Bacillus subtilis

scientific article published on November 2005

Assembly of an oxalate decarboxylase produced under sigmaK control into the Bacillus subtilis spore coat.

scientific article

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of childhood traumatization and neuropsychiatric outcomes with altered plasma micro RNA-levels

scientific article published on 08 July 2019

Associations between Serum Sex Hormone Concentrations and Whole Blood Gene Expression Profiles in the General Population

scientific article published on 22 May 2015

Associations between adipose tissue volume and small molecules in plasma and urine among asymptomatic subjects from the general population

scientific article published on 30 January 2020

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study.

scientific article published on 14 October 2015

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

scientific article

AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community

scientific article

Blood RNA expression profiles undergo major changes during the seventh decade

scientific article published on 17 September 2016

Bone marrow-derived macrophages from BALB/c and C57BL/6 mice fundamentally differ in their respiratory chain complex proteins, lysosomal enzymes and components of antioxidant stress systems

scientific article published on 01 April 2014

Brain derived neurotrophic factor contributes to the cardiogenic potential of adult resident progenitor cells in failing murine heart.

scientific article published on 23 March 2015

CcpA forms complexes with CodY and RpoA in Bacillus subtilis

scientific journal article

Cell Specific eQTL Analysis without Sorting Cells

scientific article published on 8 May 2015

Cell specific eQTL analysis without sorting cells

Cellular concentrations of the transporters DctA, DcuB, and the sensor DcuS of Escherichia coli and the contributions of free and complexed DcuS to transcriptional regulation by DcuR.

scientific article

Cerebral small vessel disease genomics and its implications across the lifespan

scientific article published on 08 December 2020

Changes of DNA topology affect the global transcription landscape and allow rapid growth of a Bacillus subtilis mutant lacking carbon catabolite repression

scientific article published on 11 December 2017

Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

scientific article published on 13 July 2016

Characterization of human and Staphylococcus aureus proteins in respiratory mucosa by in vivo- and immunoproteomics

scientific article published on 15 January 2017

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

scientific article published on October 2013

Characterization of the Genetic Program Linked to the Development of Atrial Fibrillation in CREM-IbΔC-X Mice.

scientific article published on August 2017

Characterization of the Human Myocardial Proteome in Inflammatory Dilated Cardiomyopathy by Label-free Quantitative Shotgun Proteomics of Heart Biopsies

scientific article published on 01 April 2011

Characterization of the human myocardial proteome in dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies

scientific article

Characterization of the human neutrophil alloantigen-3a

scientific article published on 27 December 2009

Chill induction of the SigB-dependent general stress response in Bacillus subtilis and its contribution to low-temperature adaptation

scientific article published on August 2003

Circulating proteomic patterns in AF related left atrial remodeling indicate involvement of coagulation and complement cascade

Cloning, nucleotide sequence, and expression of the Bacillus subtilis lon gene.

scientific article

Cloning, sequencing, mapping, and transcriptional analysis of the groESL operon from Bacillus subtilis

scientific article

ClpP modulates the activity of the Bacillus subtilis stress response transcription factor, sigmaB.

scientific article

Cohort Profile Update: The Study of Health in Pomerania (SHIP)

scientific article published in 2022

Cohort Profile: The Study of Health in Pomerania

article

Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

scientific article

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Comparative analysis of Salivette® and paraffin gum preparations for establishment of a metaproteomics analysis pipeline for stimulated human saliva

scientific article published on 24 January 2018

Comparative evaluation of peptide desalting methods for salivary proteome analysis

scientific article published on 18 April 2014

Comparative evaluation of saliva collection methods for proteome analysis

scientific article published on 04 February 2013

Comparative proteome analysis reveals conserved and specific adaptation patterns of Staphylococcus aureus after internalization by different types of human non-professional phagocytic host cells

scientific article

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

scientific article

Comparison of genotyping using pooled DNA samples (allelotyping) and individual genotyping using the affymetrix genome-wide human SNP array 6.0.

scientific article

Comparison of the proteome of Methylobacterium extorquens AM1 grown under methylotrophic and nonmethylotrophic conditions

scientific article

Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis

scientific article

Complete primary structure of a newly characterized galactose-specific lectin from the seeds of Dolichos lablab.

scientific article

Comprehensive Metabolic Profiling Reveals a Lipid-Rich Fingerprint of Free Thyroxine Far Beyond Classic Parameters

scientific article published on 01 May 2018

Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis

scientific article published on April 2005

Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis

scientific article

Copy number variants in lipid metabolism genes are associated with gallstones disease in men

scientific article published on 04 September 2019

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Correlates of adverse outcomes in abdominally obese individuals: findings from the five-year followup of the population-based study of health in Pomerania

scientific article published on 26 September 2013

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

scientific article published on 17 December 2015

Costs of life - Dynamics of the protein inventory of Staphylococcus aureus during anaerobiosis

scientific article

Cross-Sectional Association of Salivary Proteins with Age, Sex, Body Mass Index, Smoking, and Education.

scientific article

Data on the impact of the blood sample collection methods on blood protein profiling studies.

scientific article published on 14 July 2017

Defining the structure of the general stress regulon of Bacillus subtilis using targeted microarray analysis and random forest classification

scientific article published on 15 December 2011

Deletion of membrane-associated Asp23 leads to upregulation of cell wall stress genes in Staphylococcus aureus

article

Differences in the whole saliva baseline proteome profile associated with development of oral mucositis in head and neck cancer patients undergoing radiotherapy

scientific article

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

scientific article published in 2021

Direct mass spectrometric identification of ABCB1 (P-glycoprotein/MDR1) from the apical membrane fraction of human placenta using fourier transform ion cyclotron mass spectrometry.

scientific article published in June 2006

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non-carriers

article

Dynamic adaptation of myocardial proteome during heart failure development

scientific article published on 3 October 2017

Early storage lesions in apheresis platelets are induced by the activation of the integrin αIIbβ3 and focal adhesion signaling pathways

scientific article published on 24 May 2012

Effect of Experimental Thyrotoxicosis onto Blood Coagulation: A Proteomics Study

scientific article published on 28 May 2015

Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells

scientific article published on 15 October 2008

Effects of irbesartan on gene expression revealed by transcriptome analysis of left atrial tissue in a porcine model of acute rapid pacing in vivo

scientific article published on 12 February 2013

Efficient, Global-Scale Quantification of Absolute Protein Amounts by Integration of Targeted Mass Spectrometry and Two-Dimensional Gel-Based Proteomics

scientific article published on 11 March 2011

Endomyocardial proteomic signature corresponding to the response of patients with dilated cardiomyopathy to immunoadsorption therapy

scientific article published on 8 September 2016

Environmental factors affecting the expression of pilAB as well as the proteome and transcriptome of the grass endophyte Azoarcus sp. strain BH72.

scientific article

Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP).

scientific article published on 13 January 2006

Erratum to: Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

scientific article published in July 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

scientific article published in July 2017

Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis

scientific article published on 22 January 2021

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

scientific article

Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives

scientific article published on 26 October 2017

Evidence for synergistic control of glutamate biosynthesis by glutamate dehydrogenases and glutamate in Bacillus subtilis

scientific article published on 27 March 2015

Exercise Training in Patients with Chronic Heart Failure Promotes Restoration of High-Density Lipoprotein Functional Properties

scientific article published on 20 September 2013

Exome Variant Analysis of Chronic Periodontitis in 2 Large Cohort Studies

scientific article

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment

scientific article published on 8 December 2015

Exploring metal availability in the natural niche of Streptococcus pneumoniae to discover potential vaccine antigens

scientific article published on 01 December 2020

Expression of the sigmaB-dependent general stress regulon confers multiple stress resistance in Bacillus subtilis.

scientific article

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

scientific article published on 15 October 2015

Fifteen Genetic Loci Associated With the Electrocardiographic P Wave

scientific article

First steps from a two-dimensional protein index towards a response-regulation map for Bacillus subtilis

scientific article published on 01 August 1997

Fluvastatin mediated breast cancer cell death: a proteomic approach to identify differentially regulated proteins in MDA-MB-231 cells

scientific article

Forespore-specific transcription of the lonB gene during sporulation in Bacillus subtilis

scientific article

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies

scientific article

From genomics via proteomics to cellular physiology of the Gram-positive model organism Bacillus subtilis

scientific article

From the genome sequence via the proteome to cell physiology - Pathoproteomics and pathophysiology of Staphylococcus aureus

scientific article published on 5 January 2018

Fucosyltransferase 2 (FUT2) non-secretor status and blood group B are associated with elevated serum lipase activity in asymptomatic subjects, and an increased risk for chronic pancreatitis: a genetic association study

Functional abdominal pain and discomfort (IBS) is not associated with faecal microbiota composition in the general population

article

Functional and Structural Characterization of RsbU, a Stress Signaling Protein Phosphatase 2C

scientific article published in Journal of Biological Chemistry

Functional genomics of  the initial phase of cold adaptation of Pseudomonas putida KT2440

scientific article published on 01 March 2011

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium

scientific article

Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons

scientific article

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

General stress response of Bacillus subtilis and other bacteria

scientific article (publication date: 2001)

Genetic Variants Associated with Circulating Parathyroid Hormone

scientific article published on 07 December 2016

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

scientific article published on 22 September 2020

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

scientific article

Genetic determinants of serum testosterone concentrations in men.

scientific article

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

scientific article published on 20 January 2020

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

scientific article

Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality

scientific article published on 9 September 2015

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.

scientific article

Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.

scientific article published on 24 June 2019

Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis

article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association and targeted analysis of copy number variants with psoriatic arthritis in German patients

scientific article published on 23 August 2017

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association study for endothelial growth factors

scientific article published on 31 December 2014

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study of chronic periodontitis in a general German population

scientific journal article

Genome-wide association study of kidney function decline in individuals of European descent

scientific article

Genome-wide association study of pathological gambling

scientific article published on 14 June 2016

Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide transcriptional profiling analysis of adaptation of Bacillus subtilis to high salinity

scientific article

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

scientific article published on 21 June 2016

Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis

scientific article

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

scientific article published on 24 April 2017

Global analysis of the impact of linezolid onto virulence factor production in S. aureus USA300.

scientific article published on 17 February 2016

Glycerol-3-phosphate-induced catabolite repression in Escherichia coli

scientific article published on June 2002

Heat-shock and general stress response in Bacillus subtilis.

scientific article published on February 1996

Helicobacter pylori infection associates with fecal microbiota composition and diversity

scientific article published on 27 December 2019

High-Salinity-Induced Iron Limitation in Bacillus subtilis

scientific article published on February 1, 2002

Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells.

scientific article

Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cells

scientific article published on 8 May 2007

Histone deacetylase inhibitors, but not vincristine, cooperate with radiotherapy to induce cell death in medulloblastoma.

scientific article published on January 2007

How mathematical modelling elucidates signalling in Bacillus subtilis

scientific article published on September 2010

Human immune proteome in experimental colonization with Staphylococcus aureus

scientific article published on 16 September 2009

Hypermetabolic syndrome as a consequence of repeated psychological stress in mice

scientific article published on 6 March 2008

Identification of Pseudomonas proteins coordinately induced by acidic amino acids and their amides: a two-dimensional electrophoresis study

scientific article published in October 2003

Identification of genetic loci associated with Helicobacter pylori serologic status

scientific article published in May 2013

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

scientific article

Identification of periodontitis associated changes in the proteome of whole human saliva by mass spectrometric analysis

scientific article published on 23 June 2013

Immune Cell Activation by Enterotoxin Gene Cluster (egc)-Encoded and Non-egc Superantigens from Staphylococcus aureus

article

Immunoadsorption and subsequent immunoglobulin substitution decreases myocardial gene expression of desmin in dilated cardiomyopathy

article

Impact of Storage Conditions on the Breast Milk Peptidome

scientific article published on 08 September 2020

Impact of blood sample collection methods on blood protein profiling studies

scientific article published on 31 May 2017

Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood

scientific article

Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity

article

Impaired HDL function in obese adolescents: impact of lifestyle intervention and bariatric surgery

scientific article published on 13 August 2013

Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis

scientific article

Improved risk stratification in prevention by use of a panel of selected circulating microRNAs

scientific article

Improving Proteome Coverage for Small Sample Amounts: An Advanced Method for Proteomics Approaches with Low Bacterial Cell Numbers

scientific article published on 03 October 2019

In vivo Proteomics Approaches for the Analysis of Bacterial Adaptation Reactions in Host–Pathogen Settings

scientific article published on 01 January 2018

In-depth proteomic analysis of the human cerumen-a potential novel diagnostically relevant biofluid.

scientific article published on 18 March 2013

Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania

scientific article

Increased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation

scientific article

Induction of stress proteins by sodium chloride treatment in Bacillus subtilis

scientific article

Influence of doxorubicin on gene expression and protein pattern in HeLa cells

article

Inhibition of Rho Activity Increases Expression of SaeRS-Dependent Virulence Factor Genes in Staphylococcus aureus, Showing a Link between Transcription Termination, Antibiotic Action, and Virulence

article

Integration of "omics" techniques: Dronedarone affects cardiac remodeling in the infarction border zone

scientific article published on 01 July 2018

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

Kidney protein profiling of Wilms' tumor patients by analysis of formalin-fixed paraffin-embedded tissue samples.

scientific article published on 27 March 2014

Labeling of the pathogenic bacterium Staphylococcus aureus with gold or ferric oxide-core nanoparticles highlights new capabilities for investigation of host-pathogen interactions

scientific article published on 17 December 2013

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

scientific article published on 10 April 2017

Large-scale reduction of the Bacillus subtilis genome: consequences for the transcriptional network, resource allocation, and metabolism

scientific article

Low dose proteasome inhibition affects alternative splicing

scientific article

Mapping the genetic architecture of gene regulation in whole blood

scientific article

Mass spectrometric phosphoproteome analysis of small-sized samples of human neutrophils

scientific article published in October 2015

Mendelian randomization suggests non-causal associations of testosterone with cardiometabolic risk factors and mortality

scientific article published on 26 August 2012

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

scientific article published on 12 September 2016

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

scientific article published on 29 April 2012

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

scientific article

Metabolic Cross-talk Between Human Bronchial Epithelial Cells and Internalized as a Driver for Infection

scientific article published on 26 February 2019

Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study

scientific article

Metabolic adaptation and protein complexes in prokaryotes

scientific article published on 16 November 2012

Metabolic niche adaptation of community- and hospital-associated methicillin-resistant Staphylococcus aureus

scientific article published on 12 October 2018

Metaproteomics analysis of microbial diversity of human saliva and tongue dorsum in young healthy individuals

scientific article published on 26 August 2019

Molecular fingerprint of high fat diet induced urinary bladder metabolic dysfunction in a rat model

scientific article (publication date: 2013)

Monitoring of changes in the membrane proteome during stationary phase adaptation of Bacillus subtilis using in vivo labeling techniques

scientific article published in May 2008

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multidrug resistance-related protein 2 genotype of the donor affects kidney graft function

scientific article published in April 2009

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

Multiple loci are associated with white blood cell phenotypes

scientific article

Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy

scientific article published on 25 October 2012

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

scientific article published on 30 March 2017

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New loci associated with kidney function and chronic kidney disease

scientific article

Nitrogen Starvation-Induced Chlorosis in Synechococcus PCC 7942. Low-Level Photosynthesis As a Mechanism of Long-Term Survival

scientific article published on 01 May 2001

Non-specific, general and multiple stress resistance of growth-restricted Bacillus subtilis cells by the expression of the sigmaB regulon.

scientific article

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing

scientific article (publication date: June 2009)

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

scientific article published on 30 January 2014

OMICS-based exploration of the molecular phenotype of resident cardiac progenitor cells from adult murine heart

scientific article published on 27 June 2012

One of two osmC homologs in Bacillus subtilis is part of the sigmaB-dependent general stress regulon.

scientific article published on August 1998

Osmotic control of opuA expression in Bacillus subtilis and its modulation in response to intracellular glycine betaine and proline pools

scientific article published on 21 November 2012

Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase

scientific article (publication date: December 2002)

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

scientific article published in Nature Communications

PROGRESS - prospective observational study on hospitalized community acquired pneumonia

scientific article published on 28 July 2016

Pathophysiological aldosterone levels modify the secretory activity of cardiac progenitor cells.

scientific article published on 11 October 2016

Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon.

scientific article published on 8 October 2010

Plasma protein profiling of patients with intraductal papillary mucinous neoplasm of the pancreas as potential precursor lesions of pancreatic cancer

scientific article published on 5 December 2017

Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model

scientific article

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Pneumococcal Metabolic Adaptation and Colonization Are Regulated by the Two-Component Regulatory System 08.

scientific article published on 16 May 2018

Pneumococcal metabolic adaptation and colonization is regulated by the two-component regulatory system 08

Post-invasion events after infection with Staphylococcus aureus are strongly dependent on both the host cell type and the infecting S. aureus strain

scientific article published on 5 July 2016

Potential role of antibodies against cardiac Kv channel-interacting protein 2 in dilated cardiomyopathy

scientific article published on 16 May 2008

Predicting brain structure in population-based samples with biologically informed genetic scores for schizophrenia

scientific article published on April 2017

Profiling alterations in platelets induced by Amotosalen/UVA pathogen reduction and gamma irradiation--a LC-ESI-MS/MS-based proteomics approach

scientific article published on May 2012

Profiling and validation of circulating microRNAs for cardiovascular events in patients presenting with ST-segment elevation myocardial infarction

scientific article published on 23 December 2016

Profiling of alterations in platelet proteins during storage of platelet concentrates

scientific article published on 01 July 2007

Prostaglandin receptors mediate effects of substances released from ischaemic rat hearts on non-ischaemic cardiomyocytes

scientific article published in December 2008

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-based stable isotope probing (protein-SIP) in functional metaproteomics

scientific article published on 15 March 2012

Proteolysis of beta-galactosidase following SigmaB activation in Bacillus subtilis

scientific article published on 17 April 2012

Proteome analysis of Bordetella pertussis isolated from human macrophages

scientific article published on 9 February 2016

Proteome analysis of heart biopsies using a TRIzol-based protein extraction

scientific article published on 03 September 2014

Proteome analysis of host–pathogen interactions: Investigation of pathogen responses to the host cell environment

scientific article published on June 28, 2011

Proteome analysis reveals new mechanisms of Bcl11b-loss driven apoptosis

scientific article

Proteome changes in platelets after pathogen inactivation--an interlaboratory consensus

scientific article published on 25 February 2014

Proteome data from a host-pathogen interaction study with Staphylococcus aureus and human lung epithelial cells

scientific article

Proteome data of whole saliva which are associated with development of oral mucositis in head and neck cancer patients undergoing radiotherapy

scientific article

Proteome profiles of HDL particles of patients with chronic heart failure are associated with immune response and also include bacteria proteins

scientific article published on 11 December 2015

Proteomic Changes of Tissue-Tolerable Plasma Treated Airway Epithelial Cells and Their Relation to Wound Healing

scientific article published on 11 October 2015

Proteomic analyses of age related changes in A.BY/SnJ mouse hearts

scientific article published on July 2013

Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches.

scientific article

Proteomic characterization of apilRregulatory mutant ofAzoarcussp. strain BH72 with the aid of gel-based and gel-free approaches

scientific article published on 01 February 2010

Proteomic characterization of freeze-dried human plasma: providing treatment of bleeding disorders without the need for a cold chain

scientific article published on 22 July 2008

Proteomic identification of potential prognostic biomarkers in resectable pancreatic ductal adenocarcinoma.

scientific article

Proteomic profile of platelets during reconstitution of platelet counts after apheresis

scientific article published on 17 May 2016

Proteomics approaches for the analysis of enriched microbial subpopulations and visualization of complex functional information

scientific article

Proteomics as a tool for assessment of therapeutics in transfusion medicine: evaluation of prothrombin complex concentrates

scientific article published in March 2006

Proteomics of blood-based therapeutics: a promising tool for quality assurance in transfusion medicine

scientific article published on January 2007

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Purification and biochemical characterization of a lysosomal α-fucosidase from the deuterostomia Asterias rubens

scientific article published on 17 February 2012

Quantitative analysis of the intra- and inter-subject variability of the whole salivary proteome.

scientific article

Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.

scientific article

Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits

scientific article (publication date: June 2014)

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

scientific article

Rare coding variants and X-linked loci associated with age at menarche

scientific article

Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy

scientific article published on 10 October 2011

Regression of polypoid nasal mucosa after systemic corticosteroid therapy: a proteomics study

scientific article

Regulation of biofilm aging and dispersal in by the alternative sigma factor SigB

scientific article published on 20 December 2018

Regulation of interferon-inducible proteins by doxorubicin via interferon γ-Janus tyrosine kinase-signal transducer and activator of transcription signaling in tumor cells.

scientific article published on 9 February 2012

Repeating structures of the major staphylococcal autolysin are essential for the interaction with human thrombospondin 1 and vitronectin

scientific article published on 26 December 2013

RsbV-independent induction of the SigB-dependent general stress regulon of Bacillus subtilis during growth at high temperature

scientific article

S. aureus alpha-toxin monomer binding and heptamer formation in host cell membranes - Do they determine sensitivity of airway epithelial cells toward the toxin?

scientific article published on 29 May 2020

S. aureus haemolysin A-induced IL-8 and IL-6 release from human airway epithelial cells is mediated by activation of p38- and Erk-MAP kinases and additional, cell type-specific signalling mechanisms

scientific article published on 17 February 2013

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells

scientific article published on 20 October 2016

Shotgun proteome analysis ofBordetella pertussisreveals a distinct influence of iron availability on the bacterial metabolism, virulence, and defense response

scientific article published on 05 June 2015

SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria

scientific article published on January 2007

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections

scientific article (publication date: April 2015)

Signatures of cytoplasmic proteins in the exoproteome distinguish community- and hospital-associated methicillin-resistant Staphylococcus aureus USA300 lineages.

scientific article published on 5 May 2017

Small regulatory RNA-induced growth rate heterogeneity of Bacillus subtilis

scientific article (publication date: March 2015)

Specific serum IgG at diagnosis of Staphylococcus aureus bloodstream invasion is correlated with disease progression

scientific article published on 5 July 2015

Stability of proteins out of service - The GapB case of Bacillus subtilis

scientific article

Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus

scientific article published on 10 May 2016

Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions

scientific article

Staphylococcus aureus controls interleukin-5 release in upper airway inflammation

scientific article published on 13 December 2017

Stress proteins and cross-protection by heat shock and salt stress in Bacillus subtilis

scientific article published on 01 October 1992

Sulfur-36S stable isotope labeling of amino acids for quantification (SULAQ)

scientific article published on 16 December 2011

Synthesis of the compatible solute proline by Bacillus subtilis: point mutations rendering the osmotically controlled proHJ promoter hyperactive

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

Technical report: xMAPr - High-dynamic-range (HDR) quantification of antigen-specific antibody binding

scientific article published on 01 November 2019

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The N-terminal CCHC zinc finger motif mediates homodimerization of the transcription factor BCL11B.

scientific article published on 4 December 2017

The Other Side of the RAAS: Aldosterone Improves Migration of Cardiac Progenitor Cells

scientific article

The Thyroid Hormone Transporter Mct8 Restricts Cathepsin-Mediated Thyroglobulin Processing in Male Mice through Thyroid Auto-Regulatory Mechanisms That Encompass Autophagy

journal article from 'International Journal of Molecular Sciences' published in 2021

The alternative sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host

scientific article

The androgen receptor CAG repeat polymorphism as a risk factor of low serum testosterone and its cardiometabolic effects in men

The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy

scientific article published in November 2007

The inverse link between genetic risk for schizophrenia and migraine through NMDA (N-methyl-D-aspartate) receptor activation via D-serine

scientific article published on 6 July 2016

The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis

scientific article published on 03 October 2011

The quest for bacterial allergens

scientific article published on 26 April 2018

The timing of cotE expression affects Bacillus subtilis spore coat morphology but not lysozyme resistance

scientific article published on 15 December 2006

Thioredoxin is an essential protein induced by multiple stresses in Bacillus subtilis.

scientific article published on April 1998

Thyrotropin serum levels are differentially associated with biochemical markers of bone turnover and stiffness in women and men: results from the SHIP cohorts

scientific article published on 12 August 2015

Time-resolved quantitative proteome profiling of host-pathogen interactions: the response of Staphylococcus aureus RN1HG to internalisation by human airway epithelial cells

scientific article

Towards a comprehensive understanding of Bacillus subtilis cell physiology by physiological proteomics

scientific article

Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure

scientific article published on 07 August 2017

Transfusion medicine and proteomics. Alliance or coexistence?

scientific article published on June 2010

Translating pharmacological findings from hypothyroid rodents to euthyroid humans: is there a functional role of endogenous 3,5-T2?

scientific article

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Urine Metabolomics by (1)H-NMR Spectroscopy Indicates Associations between Serum 3,5-T2 Concentrations and Intermediary Metabolism in Euthyroid Humans

scientific article

Using a Label Free Quantitative Proteomics Approach to Identify Changes in Protein Abundance in Multidrug-Resistant Mycobacterium tuberculosis.

scientific article

Utilising the EGFR interactome to identify mechanisms of drug resistance in non-small cell lung cancer - Proof of concept towards a systems pharmacology approach

scientific article published on 22 April 2016

Viral myocarditis induced by Coxsackievirus B3 in A.BY/SnJ mice: Analysis of changes in the myocardial proteome

scientific article published on 01 May 2010

Virus-induced dilated cardiomyopathy is characterized by increased levels of fibrotic extracellular matrix proteins and reduced amounts of energy-producing enzymes

scientific article

Zyxin is important for the stability and function of podocytes, especially during mechanical stretch

scientific article published in 2024

σB-dependent regulation ofgsiB in response to multiple stimuli inBacillus subtilis

scientific article published on 01 July 1995