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List of works by Jacques A Nunes

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28.

scientific article published on 14 March 2018

ADAPted secretion of cytokines in NK cells.

scientific article published in November 2013

An Emerging Role for PI5P in T Cell Biology.

scientific article published on 2 April 2013

Analysis of signaling events by dynamic phosphoflow cytometry.

scientific article published in September 2009

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

scientific article

CD28 costimulation promotes an antitumor CD8+ T cell response in myeloid antigen-presenting cell niches

scientific article published in 2021

CD28 deletion improves obesity-induced liver steatosis but increases adiposity in mice

scientific article published on 16 March 2015

Cholera toxin inhibits the increase in cytoplasmic free calcium induced via the CD2 pathway of human T-lymphocyte activation

scientific article published on 01 April 1989

Chronic IL-15 Stimulation and Impaired mTOR Signaling and Metabolism in Natural Killer Cells During Acute Myeloid Leukemia

scientific article published on 17 December 2021

Constitutive AKT activation in follicular lymphoma

scientific article

Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.

scientific article published on 15 June 2015

Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells.

scientific article

Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA.

scientific article

Differential role for CD277 as a co-regulator of the immune signal in T and NK cells

scientific article

Dok-4 is a novel negative regulator of T cell activation.

scientific article

Dok1 and Dok2 Proteins Regulate Cell Cycle in Hematopoietic Stem and Progenitor Cells.

scientific article published on 18 April 2016

Dok1 and Dok2 proteins regulate natural killer cell development and function

scientific article

Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells

scientific article

Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways.

scientific article published on 24 April 2010

Evolutionary and expression analyses reveal a pattern of ancient duplications and functional specializations in the diversification of the Downstream of Kinase (DOK) genes.

scientific article published on 14 February 2018

Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes

scientific article published on 22 March 2018

Flow cytometric analysis of intracellular phosphoproteins in human monocytes.

scientific article

Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase

scientific article (publication date: 26 February 2004)

Hepatitis C virus fails to activate NF-κB signaling in plasmacytoid dendritic cells

scientific article published on 16 November 2011

In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation.

scientific article published on March 2015

Modulation of T Cell Activation in Obesity

scientific article published on 25 May 2016

Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML)

article

Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus

scientific article published in July 2001

PD-L2 is expressed on activated human T cells and regulates their function

scientific article published on 12 July 2011

Regions of the CD8 molecule involved in the regulation of CD2-mediated activation.

scientific article published on September 1994

Regulation of CD2-mediated human T cell activation: anti-CD8 monoclonal antibodies inhibit CD2-mediated rise in intracellular calcium

scientific article published on 01 November 1993

T Cells on Engineered Substrates: The Impact of TCR Clustering Is Enhanced by LFA-1 Engagement

scientific article published on 18 September 2018

T cell activation via the CD2 molecule is associated with protein kinase C translocation from the cytosol to the plasma membrane

scientific article published on 01 May 1989

TCR and CD28 Concomitant Stimulation Elicits a Distinctive Calcium Response in Naive T Cells

scientific article published on 04 December 2018

The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule.

scientific article

Travel informations on the Tec kinases during lymphocyte activation.

scientific article published on January 2006

Triggering CD 28 molecules synergize with CD 2 (T 11.1 and T 11.2)-mediated T cell activation.

scientific article

Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer.

scientific article published on 6 June 2019

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